6UPH
| Structure of a Yeast Centromeric Nucleosome at 2.7 Angstrom resolution | 分子名称: | DNA (119-MER), Histone H2A, Histone H2B.1, ... | 著者 | Migl, D, Kschonsak, M, Arthur, C.P, Khin, Y, Harrison, S.C, Ciferri, C, Dimitrova, Y.N. | 登録日 | 2019-10-17 | 公開日 | 2019-11-06 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Cryoelectron Microscopy Structure of a Yeast Centromeric Nucleosome at 2.7 angstrom Resolution. Structure, 28, 2020
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7RSJ
| Structure of the VPS34 kinase domain with compound 14 | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, N-{4-[(7R,8R)-4-oxo-7-(propan-2-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-yl]pyridin-2-yl}cyclopropanecarboxamide, ... | 著者 | Hu, D.X, Patel, S, Chen, H, Wang, S, Staben, S, Dimitrova, Y.N, Wallweber, H.A, Lee, J.Y, Chan, G.K.Y, Sneeringer, C.J, Prangley, M.S, Moffat, J.G, Wu, C, Schutt, L.K, Salphati, L, Pang, J, McNamara, E, Huang, H, Chen, Y, Wang, Y, Zhao, W, Lim, J, Murthy, A, Siu, M. | 登録日 | 2021-08-11 | 公開日 | 2021-11-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.881 Å) | 主引用文献 | Structure-Based Design of Potent, Selective, and Orally Bioavailable VPS34 Kinase Inhibitors. J.Med.Chem., 65, 2022
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7RSP
| Structure of the VPS34 kinase domain with compound 14 | 分子名称: | (7R,8R)-2-[(3R)-3-methylmorpholin-4-yl]-7-(propan-2-yl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one, GLYCEROL, Phosphatidylinositol 3-kinase catalytic subunit type 3 | 著者 | Hu, D.X, Patel, S, Chen, H, Wang, S, Staben, S, Dimitrova, Y.N, Wallweber, H.A, Lee, J.Y, Chan, G.K.Y, Sneeringer, C.J, Prangley, M.S, Moffat, J.G, Wu, C, Schutt, L.K, Salphati, L, Pang, J, McNamara, E, Huang, H, Chen, Y, Wang, Y, Zhao, W, Lim, J, Murthy, A, Siu, M. | 登録日 | 2021-08-11 | 公開日 | 2021-11-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Structure-Based Design of Potent, Selective, and Orally Bioavailable VPS34 Kinase Inhibitors. J.Med.Chem., 65, 2022
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7RSV
| Structure of the VPS34 kinase domain with compound 5 | 分子名称: | (5aS,8aR,9S)-2-[(3R)-3-methylmorpholin-4-yl]-5,5a,6,7,8,8a-hexahydro-4H-cyclopenta[e]pyrazolo[1,5-a]pyrazin-4-one, GLYCEROL, Phosphatidylinositol 3-kinase catalytic subunit type 3, ... | 著者 | Hu, D.X, Patel, S, Chen, H, Wang, S, Staben, S, Dimitrova, Y.N, Wallweber, H.A, Lee, J.Y, Chan, G.K.Y, Sneeringer, C.J, Prangley, M.S, Moffat, J.G, Wu, C, Schutt, L.K, Salphati, L, Pang, J, McNamara, E, Huang, H, Chen, Y, Wang, Y, Zhao, W, Lim, J, Murthy, A, Siu, M. | 登録日 | 2021-08-11 | 公開日 | 2021-11-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Structure-Based Design of Potent, Selective, and Orally Bioavailable VPS34 Kinase Inhibitors. J.Med.Chem., 65, 2022
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5T58
| Structure of the MIND Complex Shows a Regulatory Focus of Yeast Kinetochore Assembly | 分子名称: | KLLA0C15939p, KLLA0D15741p, KLLA0E05809p, ... | 著者 | Dimitrova, Y, Jenni, S, Valverde, R, Khin, Y, Harrison, S.C. | 登録日 | 2016-08-30 | 公開日 | 2016-11-09 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.2131 Å) | 主引用文献 | Structure of the MIND Complex Defines a Regulatory Focus for Yeast Kinetochore Assembly. Cell, 167, 2016
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5T51
| Structure of the MIND Complex Shows a Regulatory Focus of Yeast Kinetochore Assembly | 分子名称: | KLLA0E05809p, KLLA0F02343p, SULFATE ION | 著者 | Dimitrova, Y, Jenni, S, Valverde, R, Khin, Y, Harrison, S.C. | 登録日 | 2016-08-30 | 公開日 | 2016-11-09 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.2007 Å) | 主引用文献 | Structure of the MIND Complex Defines a Regulatory Focus for Yeast Kinetochore Assembly. Cell, 167, 2016
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5T59
| Structure of the MIND Complex Shows a Regulatory Focus of Yeast Kinetochore Assembly | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, KLLA0B13629p, KLLA0E05809p, ... | 著者 | Dimitrova, Y, Jenni, S, Valverde, R, Khin, Y, Harrison, S.C. | 登録日 | 2016-08-30 | 公開日 | 2016-11-09 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.405 Å) | 主引用文献 | Structure of the MIND Complex Defines a Regulatory Focus for Yeast Kinetochore Assembly. Cell, 167, 2016
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5T6J
| Structure of the MIND Complex Shows a Regulatory Focus of Yeast Kinetochore Assembly | 分子名称: | Kinetochore protein SPC24, Kinetochore protein SPC25, Kinetochore-associated protein DSN1 | 著者 | Valverde, R, Jenni, S, Dimitrova, Y, Khin, Y, Harrison, S.C. | 登録日 | 2016-09-01 | 公開日 | 2016-11-09 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.752 Å) | 主引用文献 | Structure of the MIND Complex Defines a Regulatory Focus for Yeast Kinetochore Assembly. Cell, 167, 2016
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5LSK
| CRYSTAL STRUCTURE OF THE HUMAN KINETOCHORE MIS12-CENP-C COMPLEX | 分子名称: | Centromere protein C, Kinetochore-associated protein DSN1 homolog, Kinetochore-associated protein NSL1 homolog, ... | 著者 | Vetter, I.R, Petrovic, A, Keller, J, Liu, Y. | 登録日 | 2016-09-02 | 公開日 | 2016-11-16 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (3.502 Å) | 主引用文献 | Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores. Cell, 167, 2016
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6OXB
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5LSJ
| CRYSTAL STRUCTURE OF THE HUMAN KINETOCHORE MIS12-CENP-C delta-HEAD2 COMPLEX | 分子名称: | Centromere protein C, Kinetochore-associated protein DSN1 homolog, Kinetochore-associated protein NSL1 homolog, ... | 著者 | Vetter, I.R, Petrovic, A, Keller, J, Liu, Y. | 登録日 | 2016-09-02 | 公開日 | 2016-11-16 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores. Cell, 167, 2016
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5LSI
| CRYSTAL STRUCTURE OF THE KINETOCHORE MIS12 COMPLEX HEAD2 SUBDOMAIN CONTAINING DSN1 AND NSL1 FRAGMENTS | 分子名称: | Kinetochore-associated protein DSN1 homolog, Kinetochore-associated protein NSL1 homolog, SULFATE ION | 著者 | Vetter, I.R, Petrovic, A, Keller, J, Liu, Y. | 登録日 | 2016-09-02 | 公開日 | 2016-11-16 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.002 Å) | 主引用文献 | Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores. Cell, 167, 2016
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2JTT
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2KR4
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