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4IKF
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BU of 4ikf by Molmil
PFV intasome with inhibitor MB-76
分子名称: 5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3', 5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3', AMMONIUM ION, ...
著者Taltynov, O, Demeulemeester, J, Desimmie, B.A, Suchaud, V, Billamboz, M, Lion, C, Bailly, F, Debyser, Z, Cotelle, P, Christ, F, Strelkov, S.V.
登録日2012-12-26
公開日2013-04-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献2-Hydroxyisoquinoline-1,3(2H,4H)-diones (HIDs), novel inhibitors of HIV integrase with a high barrier to resistance.
Acs Chem.Biol., 8, 2013
6NIL
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BU of 6nil by Molmil
cryoEM structure of the truncated HIV-1 Vif/CBFbeta/A3F complex
分子名称: Core-binding factor subunit beta, DNA dC->dU-editing enzyme APOBEC-3F, Virion infectivity factor, ...
著者Hu, Y, Xiong, Y.
登録日2018-12-29
公開日2019-12-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis of antagonism of human APOBEC3F by HIV-1 Vif.
Nat.Struct.Mol.Biol., 26, 2019
6BWY
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BU of 6bwy by Molmil
DNA substrate selection by APOBEC3G
分子名称: DNA (30-MER), PHOSPHATE ION, Protection of telomeres protein 1, ...
著者Ziegler, S.J, Buzovetsky, O.
登録日2017-12-15
公開日2018-04-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Insights into DNA substrate selection by APOBEC3G from structural, biochemical, and functional studies.
PLoS ONE, 13, 2018
3LPU
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BU of 3lpu by Molmil
HIV integrase
分子名称: (2S)-2-(6-chloro-2-methyl-4-phenylquinolin-3-yl)pentanoic acid, 2-[3-[3-(2-hydroxyethoxy)propoxy]propoxy]ethanol, CALCIUM ION, ...
著者Nicolet, S, Christ, F, Voet, A, Marchand, A, Strelkov, S.V, de Maeyer, M, Chaltin, P, Debyzer, Z.
登録日2010-02-06
公開日2010-05-12
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication.
Nat.Chem.Biol., 6, 2010
3LPT
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BU of 3lpt by Molmil
HIV integrase
分子名称: (6-chloro-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)acetic acid, 2-[3-[3-(2-hydroxyethoxy)propoxy]propoxy]ethanol, CALCIUM ION, ...
著者Nicolet, S, Christ, F, Voet, A, Marchand, A, Strelkov, S.V, de Maeyer, M, Chaltin, P, Debyzer, Z.
登録日2010-02-05
公開日2010-05-12
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication.
Nat.Chem.Biol., 6, 2010

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件を2024-07-17に公開中

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