4IKF
 
 | | PFV intasome with inhibitor MB-76 | | 分子名称: | 5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3', 5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3', AMMONIUM ION, ... | | 著者 | Taltynov, O, Demeulemeester, J, Desimmie, B.A, Suchaud, V, Billamboz, M, Lion, C, Bailly, F, Debyser, Z, Cotelle, P, Christ, F, Strelkov, S.V. | | 登録日 | 2012-12-26 | | 公開日 | 2013-04-03 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | 2-Hydroxyisoquinoline-1,3(2H,4H)-diones (HIDs), novel inhibitors of HIV integrase with a high barrier to resistance.
Acs Chem.Biol., 8, 2013
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2MSR
 | | Solution structure of LEDGF/p75 IBD in complex with MLL1 peptide (140-160) | | 分子名称: | Histone-lysine N-methyltransferase 2A, PC4 and SFRS1-interacting protein | | 著者 | Cermakova, K, Tesina, P, Demeulemeester, J, El Ashkar, S, Mereau, H, Schwaller, J, Rezacova, P, Veverka, V, De Rijck, J. | | 登録日 | 2014-08-05 | | 公開日 | 2014-08-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Validation and Structural Characterization of the LEDGF/p75-MLL Interface as a New Target for the Treatment of MLL-Dependent Leukemia.
Cancer Res., 74, 2014
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2N3A
 | | Solution structure of LEDGF/p75 IBD in complex with POGZ peptide (1389-1404) | | 分子名称: | PC4 and SFRS1-interacting protein, Pogo transposable element with ZNF domain | | 著者 | Tesina, P, Cermakova, K, Horejsi, M, Prochazkova, K, Fabry, M, Sharma, S, Christ, F, Demeulemeester, J, Debyser, Z, De Rijck, J, Veverka, V, Rezacova, P. | | 登録日 | 2015-05-26 | | 公開日 | 2015-08-19 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Multiple cellular proteins interact with LEDGF/p75 through a conserved unstructured consensus motif.
Nat Commun, 6, 2015
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5YI9
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4OL0
 | | Crystal structure of transportin-SR2, a karyopherin involved in human disease, in complex with Ran | | 分子名称: | GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Tsirkone, V.G, Strelkov, S.V. | | 登録日 | 2014-01-23 | | 公開日 | 2014-04-09 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structure of transportin SR2, a karyopherin involved in human disease, in complex with Ran.
Acta Crystallogr.,Sect.F, 70, 2014
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6EMR
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6EMP
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6EMO
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6EMQ
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6ZV3
 | | TFIIS N-terminal domain (TND) from human MED26 | | 分子名称: | Mediator of RNA polymerase II transcription subunit 26 | | 著者 | Veverka, V. | | 登録日 | 2020-07-23 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A ubiquitous disordered protein interaction module orchestrates transcription elongation.
Science, 374, 2021
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6ZV1
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6ZV2
 | | TFIIS N-terminal domain (TND) from human PPP1R10 | | 分子名称: | Serine/threonine-protein phosphatase 1 regulatory subunit 10 | | 著者 | Veverka, V. | | 登録日 | 2020-07-23 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A ubiquitous disordered protein interaction module orchestrates transcription elongation.
Science, 374, 2021
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6ZUZ
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6ZV4
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6ZV0
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6ZUY
 | | Human TFIIS N-terminal domain (TND) | | 分子名称: | Transcription elongation factor A protein 1 | | 著者 | Veverka, V. | | 登録日 | 2020-07-23 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A ubiquitous disordered protein interaction module orchestrates transcription elongation.
Science, 374, 2021
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