Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
2LMA
DownloadVisualize
BU of 2lma by Molmil
Solution structure of CD4+ T cell derived peptide Thp5
分子名称: Thp5 peptide
著者Pandey, N.K, Khan, M.M, Chatterjee, S, Dwivedi, V.P, Tousif, S, Das, J, Van Kaer, L.
登録日2011-11-29
公開日2011-12-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献CD4+ T cell derived novel peptide Thp5 induces IL-4 production in CD4+ T cells to direct T helper 2 cell differentiation
J.Biol.Chem., 2011
4FKD
DownloadVisualize
BU of 4fkd by Molmil
Identification of the Activator Binding Residues in the Second Cysteine-Rich Regulatory Domain of Protein Kinase C Theta
分子名称: Protein kinase C theta type, ZINC ION
著者Rahman, G.M, Shanker, S, Lewin, N.E, Prasad, B.V.V, Blumberg, P.M, Das, J.
登録日2012-06-13
公開日2013-01-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.633 Å)
主引用文献Identification of the Activator Binding Residues in the Second Cysteine-Rich Regulatory Domain of Protein Kinase C Theta.
Biochem.J., 451, 2013
7W61
DownloadVisualize
BU of 7w61 by Molmil
Crystal structure of farnesol dehydrogenase from Helicoverpa armigera
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Farnesol dehydrogenase, ...
著者Kumar, R, Das, J, Mahto, J.K, Sharma, M, Kumar, P, Sharma, A.K.
登録日2021-12-01
公開日2022-07-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure and molecular characterization of NADP + -farnesol dehydrogenase from cotton bollworm, Helicoverpaarmigera.
Insect Biochem.Mol.Biol., 147, 2022
3TU7
DownloadVisualize
BU of 3tu7 by Molmil
Human alpha-thrombin complexed with N-(methylsulfonyl)-D-phenylalanyl-N-((1-carbamimidoyl-4-piperidinyl)methyl)-l-prolinamide (BMS-189664)
分子名称: Hirudin variant-2, N-(methylsulfonyl)-D-phenylalanyl-N-[(1-carbamimidoylpiperidin-4-yl)methyl]-L-prolinamide, Prothrombin
著者Malley, M, Sack, J.S.
登録日2011-09-16
公開日2011-10-12
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Molecular design and structure-activity relationships leading to the potent, selective, and orally active thrombin active site inhibitor BMS-189664.
Bioorg.Med.Chem.Lett., 12, 2002
3L8X
DownloadVisualize
BU of 3l8x by Molmil
P38 alpha kinase complexed with a pyrazolo-pyrimidine based inhibitor
分子名称: Mitogen-activated protein kinase 14, N,4-dimethyl-3-[(1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino]benzamide
著者Sack, J.S.
登録日2010-01-04
公開日2010-03-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Pyrazolo-Pyrimidines: A Novel Heterocyclic Scaffold for Potent and Selective P38 Alpha Inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
3OCG
DownloadVisualize
BU of 3ocg by Molmil
P38 Alpha kinase complexed with a 5-amino-pyrazole based inhibitor
分子名称: 5-amino-N-[5-(isoxazol-3-ylcarbamoyl)-2-methylphenyl]-1-phenyl-1H-pyrazole-4-carboxamide, Mitogen-activated protein kinase 14
著者Sack, J.S.
登録日2010-08-10
公開日2010-11-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献5-Amino-pyrazoles as potent and selective p38α inhibitors
Bioorg.Med.Chem.Lett., 20, 2010
5WFJ
DownloadVisualize
BU of 5wfj by Molmil
THE JAK3 KINASE DOMAIN IN COMPLEX WITH A COVALENT INHIBITOR
分子名称: 4-({[3-(propanoylamino)phenyl]methyl}amino)pyrrolo[1,2-b]pyridazine-3-carboxamide, Tyrosine-protein kinase JAK3
著者Sack, J.
登録日2017-07-12
公開日2017-10-04
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Discovery of highly potent, selective, covalent inhibitors of JAK3.
Bioorg. Med. Chem. Lett., 27, 2017
7CT1
DownloadVisualize
BU of 7ct1 by Molmil
Crystal structure of Snx27 FERM domain in complex with a DLF motif
分子名称: Fusion protein Sorting nexin-27 and DLF motif, GLYCEROL
著者Hu, W, Da, J, Sun, Q.
登録日2020-08-17
公開日2021-08-25
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.947 Å)
主引用文献Crystal structure of Snx27 FERM domain in complex with a DLF motif
To Be Published
1BMN
DownloadVisualize
BU of 1bmn by Molmil
HUMAN ALPHA-THROMBIN COMPLEXED WITH [S-(R*,R*)]-1-(AMINOIMINOMETHYL)-N-[[1-[N-[(2-NAPHTHALENYLSULFONYL)-L-SERYL]-PYRROLIDINYL]METHYL]-3-PIPERIDENECARBOXAMIDE (BMS-189090)
分子名称: ALPHA-THROMBIN, HIRUDIN I, [S-(R*,R*)]-1-(AMINOIMINOMETHYL)-N-[[1-[N-[(2-NAPHTHALENYLSULFONYL)-L-SERYL]-3-PYRROLIDINYL]METHYL]-3-PIPERIDENECARBOXAMIDE
著者Malley, M, Sack, J.
登録日1995-11-14
公開日1996-12-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystallographic determination of the structures of human alpha-thrombin complexed with BMS-186282 and BMS-189090.
Protein Sci., 5, 1996
1BMM
DownloadVisualize
BU of 1bmm by Molmil
HUMAN ALPHA-THROMBIN COMPLEXED WITH [S-(R*,R*)]-4-[(AMINOIMINOMETHYL)AMINO]-N-[[1-[3-HYDROXY-2-[(2-NAPHTHALENYLSULFONYL)AMINO]-1-OXOPROPYL]-2-PYRROLIDINYL] METHYL]BUTANAMIDE (BMS-186282)
分子名称: ALPHA-THROMBIN, HIRUDIN I, S-(R*,R*)]-4-[AMINOIMINOMETHYL)AMINO]-N-[[1-[3-HYDROXY -2-[(2-NAPHTHALENYLSULFONYL)AMINO]-1-OXOPROPYL]-2-PYRROLIDINYL] METHYL]BUTANAMIDE
著者Malley, M, Sack, J.
登録日1995-11-14
公開日1996-12-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystallographic determination of the structures of human alpha-thrombin complexed with BMS-186282 and BMS-189090.
Protein Sci., 5, 1996
2BYV
DownloadVisualize
BU of 2byv by Molmil
Structure of the cAMP responsive exchange factor Epac2 in its auto- inhibited state
分子名称: RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 4
著者Rehmann, H, Wittinghofer, A, Bos, J.L.
登録日2005-08-08
公開日2006-02-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of the Cyclic-AMP Responsive Exchange Factor Epac2 in its Auto-Inhibited State
Nature, 439, 2006
3CF6
DownloadVisualize
BU of 3cf6 by Molmil
Structure of Epac2 in complex with cyclic-AMP and Rap
分子名称: 6-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL, Rap guanine nucleotide exchange factor (GEF) 4, Ras-related protein Rap-1b, ...
著者Rehmann, H, Arias-Palomo, E, Hadders, M.A, Schwede, F, Llorca, O, Bos, J.L.
登録日2008-03-02
公開日2008-07-29
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of Epac2 in complex with a cyclic AMP analogue and RAP1B
Nature, 455, 2008
3UEJ
DownloadVisualize
BU of 3uej by Molmil
Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase Cdelta
分子名称: PHOSPHATE ION, Protein kinase C delta type, ZINC ION
著者Shanmugasundararaj, S, Stehle, T, Miller, K.W.
登録日2011-10-30
公開日2012-12-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.301 Å)
主引用文献Structural and Functional Characterization of an Anesthetic Binding Site in the Second Cysteine-Rich Domain of Protein Kinase Cdelta
Biophys.J., 103, 2012
3UGL
DownloadVisualize
BU of 3ugl by Molmil
Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase C delta
分子名称: PHOSPHATE ION, Proteine kinase C delta type, ZINC ION, ...
著者Shanmugasundararaj, S, Stehle, T, Miller, K.W.
登録日2011-11-02
公開日2012-12-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.357 Å)
主引用文献Structural and Functional Characterization of an Anesthetic Binding Site in the Second Cysteine-Rich Domain of Protein Kinase Cdelta
Biophys.J., 103, 2012
3UFF
DownloadVisualize
BU of 3uff by Molmil
Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase Cdelta
分子名称: PHOSPHATE ION, Protein kinase C delta type, ZINC ION
著者Shanmugasundararaj, S, Stehle, T, Miller, K.W.
登録日2011-11-01
公開日2012-12-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase C delta
Biophys.J., 103, 2012
3UGI
DownloadVisualize
BU of 3ugi by Molmil
Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase C delta
分子名称: (methoxymethyl)cyclopropane, PHOSPHATE ION, Protein kinase C delta type, ...
著者Shanmugasundararaj, S, Stehle, T, Miller, K.W.
登録日2011-11-02
公開日2012-12-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.361 Å)
主引用文献Structural and Functional Characterization of an Anesthetic Binding Site in the Second Cysteine-Rich Domain of Protein Kinase Cdelta
Biophys.J., 103, 2012
3UEY
DownloadVisualize
BU of 3uey by Molmil
Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase Cdelta
分子名称: PHOSPHATE ION, Protein kinase C delta type, ZINC ION
著者Shanmugasundararaj, S, Stehle, T, Miller, K.W.
登録日2011-10-31
公開日2012-12-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.301 Å)
主引用文献Structural and Functional Characterization of an Anesthetic Binding Site in the Second Cysteine-Rich Domain of Protein Kinase Cdelta
Biophys.J., 103, 2012
3UGD
DownloadVisualize
BU of 3ugd by Molmil
Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase C delta
分子名称: 1,2-ETHANEDIOL, PHOSPHATE ION, Protein kinase C delta type, ...
著者Shanmugasundararaj, S, Stehle, T, Miller, K.W.
登録日2011-11-02
公開日2012-12-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase C delta
Biophys.J., 103, 2012

225946

件を2024-10-09に公開中

PDB statisticsPDBj update infoContact PDBjnumon