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5N4B
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BU of 5n4b by Molmil
Prolyl oligopeptidase B from Galerina marginata bound to 25mer macrocyclization substrate - S577A mutant
分子名称: Alpha-amanitin proprotein, Prolyl oligopeptidase
著者Czekster, C.M, McMahon, S.A, Ludewig, H, Naismith, J.H.
登録日2017-02-10
公開日2017-11-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Characterization of a dual function macrocyclase enables design and use of efficient macrocyclization substrates.
Nat Commun, 8, 2017
5N4E
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BU of 5n4e by Molmil
Prolyl oligopeptidase B from Galerina marginata bound to 35mer hydrolysis and macrocyclization substrate - H698A mutant
分子名称: Alpha-amanitin proprotein, GLYCEROL, Prolyl oligopeptidase
著者Czekster, C.M, McMahon, S.A, Ludewig, H, Naismith, J.H.
登録日2017-02-10
公開日2017-11-01
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Characterization of a dual function macrocyclase enables design and use of efficient macrocyclization substrates.
Nat Commun, 8, 2017
5N4C
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BU of 5n4c by Molmil
Prolyl oligopeptidase B from Galerina marginata bound to 35mer hydrolysis and macrocyclization substrate - S577A mutant
分子名称: Alpha-amanitin proprotein, GLYCEROL, Prolyl oligopeptidase
著者Czekster, C.M, McMahon, S.A, Ludewig, H, Naismith, J.H.
登録日2017-02-10
公開日2017-11-01
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Characterization of a dual function macrocyclase enables design and use of efficient macrocyclization substrates.
Nat Commun, 8, 2017
5N4D
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BU of 5n4d by Molmil
Prolyl oligopeptidase B from Galerina marginata bound to 25mer macrocyclization substrate - D661A mutant
分子名称: Alpha-amanitin proprotein, GLYCEROL, Prolyl oligopeptidase
著者Czekster, C.M, McMahon, S.A, Ludewig, H, Naismith, J.H.
登録日2017-02-10
公開日2017-11-01
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Characterization of a dual function macrocyclase enables design and use of efficient macrocyclization substrates.
Nat Commun, 8, 2017
5N4F
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BU of 5n4f by Molmil
Prolyl oligopeptidase B from Galerina marginata - apo protein
分子名称: GLYCEROL, Prolyl oligopeptidase
著者Czekster, C.M, McMahon, S.A, Ludewig, H, Naismith, J.H.
登録日2017-02-10
公開日2017-11-01
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Characterization of a dual function macrocyclase enables design and use of efficient macrocyclization substrates.
Nat Commun, 8, 2017
7AZU
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BU of 7azu by Molmil
Crystal structure of a cyclodipeptide synthase from Bacillus thermoamylovorans
分子名称: (2S)-hexane-1,2-diol, Cyclodipeptide synthase, BtCDPS
著者Harding, C.J, Czekster, C.M.
登録日2020-11-17
公開日2021-01-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献Bypassing the requirement for aminoacyl-tRNA by a cyclodipeptide synthase enzyme.
Rsc Chem Biol, 2, 2021
6ZU3
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BU of 6zu3 by Molmil
Crystal structure of a cyclodipeptide synthase from Bacillus thermoamylovorans
分子名称: Cyclodipeptide synthase, BtCDPS
著者Harding, C.J, Czekster, C.M.
登録日2020-07-21
公開日2021-01-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Bypassing the requirement for aminoacyl-tRNA by a cyclodipeptide synthase enzyme.
Rsc Chem Biol, 2, 2021
6ZTU
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BU of 6ztu by Molmil
Crystal structure of a cyclodipeptide synthase from Bacillus thermoamylovorans
分子名称: (2S)-hexane-1,2-diol, Cyclodipeptide synthase, BtCDPS
著者Harding, C.J, Czekster, C.M.
登録日2020-07-20
公開日2021-01-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Bypassing the requirement for aminoacyl-tRNA by a cyclodipeptide synthase enzyme.
Rsc Chem Biol, 2, 2021
8PZ0
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BU of 8pz0 by Molmil
Intracellular leucine aminopeptidase of Pseudomonas aeruginosa PA14.
分子名称: 1,2-ETHANEDIOL, BICARBONATE ION, CHLORIDE ION, ...
著者Simpson, M.C, Czekster, C.M, Harding, C.J.
登録日2023-07-26
公開日2023-11-15
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Unveiling the Catalytic Mechanism of a Processive Metalloaminopeptidase.
Biochemistry, 62, 2023
8PZM
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BU of 8pzm by Molmil
Intracellular leucine aminopeptidase of Pseudomonas aeruginosa PA14 bound to bestatin inhibitor and manganese
分子名称: 1,2-ETHANEDIOL, 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, BICARBONATE ION, ...
著者Simpson, M.C, Czekster, C.M, Harding, C.J.
登録日2023-07-27
公開日2023-11-15
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Unveiling the Catalytic Mechanism of a Processive Metalloaminopeptidase.
Biochemistry, 62, 2023
8PZY
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BU of 8pzy by Molmil
Intracellular leucine aminopeptidase of Pseudomonas aeruginosa PA14 - hexameric assembly with manganese bound
分子名称: 1,2-ETHANEDIOL, 2-[3-[3-(2-hydroxyethoxy)propoxy]propoxy]ethanol, AMMONIUM ION, ...
著者Simpson, M.C, Czekster, C.M, Harding, C.J.
登録日2023-07-27
公開日2023-11-15
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Unveiling the Catalytic Mechanism of a Processive Metalloaminopeptidase.
Biochemistry, 62, 2023
8ACK
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BU of 8ack by Molmil
Structure of Pseudomonas aeruginosa aminopeptidase, PaAP
分子名称: CACODYLATE ION, Keratinase KP1, PCP, ...
著者Harding, C.J, Czekster, C.M.
登録日2022-07-05
公開日2023-07-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.784 Å)
主引用文献An anti-biofilm cyclic peptide targets a secreted aminopeptidase from P. aeruginosa.
Nat.Chem.Biol., 19, 2023
8ACR
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BU of 8acr by Molmil
Structure of Pseudomonas aeruginosa aminopeptidase, PaAP
分子名称: Keratinase KP1, SODIUM ION, ZINC ION
著者Harding, C.J, Czekster, C.M.
登録日2022-07-06
公開日2023-07-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献An anti-biofilm cyclic peptide targets a secreted aminopeptidase from P. aeruginosa.
Nat.Chem.Biol., 19, 2023
8AC9
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BU of 8ac9 by Molmil
Structure of Pseudomonas aeruginosa aminopeptidase, PaAP_T
分子名称: Keratinase KP1, ZINC ION
著者Harding, C.J, Czekster, C.M.
登録日2022-07-05
公開日2023-07-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.351 Å)
主引用文献An anti-biofilm cyclic peptide targets a secreted aminopeptidase from P. aeruginosa.
Nat.Chem.Biol., 19, 2023
8ACG
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BU of 8acg by Molmil
Structure of Pseudomonas aeruginosa aminopeptidase, PaAP_T E340A mutant
分子名称: Keratinase KP1, MAGNESIUM ION, ZINC ION
著者Harding, C.J, Czekster, C.M.
登録日2022-07-05
公開日2023-07-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献An anti-biofilm cyclic peptide targets a secreted aminopeptidase from P. aeruginosa.
Nat.Chem.Biol., 19, 2023
8AC7
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BU of 8ac7 by Molmil
Structure of Pseudomonas aeruginosa aminopeptidase, PaAP
分子名称: ACETATE ION, ISOPROPYL ALCOHOL, Keratinase KP1, ...
著者Harding, C.J, Czekster, C.M.
登録日2022-07-05
公開日2023-07-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献An anti-biofilm cyclic peptide targets a secreted aminopeptidase from P. aeruginosa.
Nat.Chem.Biol., 19, 2023
7QAT
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BU of 7qat by Molmil
Crystal structure of a cyclodipeptide synthase from Parcubacteria bacterium RAAC4_OD1_1, E174L
分子名称: Cyclodipeptide synthase
著者Sutherland, E, Harding, C.J, Czekster, C.M.
登録日2021-11-17
公開日2022-09-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.402 Å)
主引用文献Active site remodelling of a cyclodipeptide synthase redefines substrate scope.
Commun Chem, 5, 2022
7QAW
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BU of 7qaw by Molmil
Crystal structure of a cyclodipeptide synthase from Parcubacteria bacterium RAAC4_OD1_1, Y189F mutant
分子名称: Cyclodipeptide synthase
著者Sutherland, E, Harding, C.J, Czekster, C.M.
登録日2021-11-17
公開日2022-09-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.285 Å)
主引用文献Active site remodelling of a cyclodipeptide synthase redefines substrate scope.
Commun Chem, 5, 2022
7QAX
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BU of 7qax by Molmil
Crystal structure of a cyclodipeptide synthase from Parcubacteria bacterium RAAC4_OD1_1, E171Q mutant
分子名称: Cyclodipeptide synthase
著者Sutherland, E, Harding, C.J, Czekster, C.M.
登録日2021-11-17
公開日2022-09-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.089 Å)
主引用文献Active site remodelling of a cyclodipeptide synthase redefines substrate scope.
Commun Chem, 5, 2022
7QAU
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BU of 7qau by Molmil
Crystal structure of a cyclodipeptide synthase from Parcubacteria bacterium RAAC4_OD1_1, D58N mutant
分子名称: Cyclodipeptide synthase
著者Sutherland, E, Harding, C.J, Czekster, C.M.
登録日2021-11-17
公開日2022-09-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Active site remodelling of a cyclodipeptide synthase redefines substrate scope.
Commun Chem, 5, 2022
7QAQ
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BU of 7qaq by Molmil
Crystal structure of a cyclodipeptide synthase from Parcubacteria bacterium RAAC4_OD1_1, E174A mutant
分子名称: Cyclodipeptide synthase
著者Sutherland, E, Harding, C.J, Czekster, C.M.
登録日2021-11-17
公開日2022-09-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Active site remodelling of a cyclodipeptide synthase redefines substrate scope.
Commun Chem, 5, 2022
7QB8
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BU of 7qb8 by Molmil
Crystal structure of a cyclodipeptide synthase from Parcubacteria bacterium RAAC4_OD1_1, WT form
分子名称: Cyclodipeptide synthase
著者Sutherland, E, Harding, C.J, Czekster, C.M.
登録日2021-11-18
公開日2022-09-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Active site remodelling of a cyclodipeptide synthase redefines substrate scope.
Commun Chem, 5, 2022
7QAY
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BU of 7qay by Molmil
Crystal structure of a cyclodipeptide synthase from Parcubacteria bacterium RAAC4_OD1_1, Y55F mutant
分子名称: Cyclodipeptide synthase
著者Sutherland, E, Harding, C.J, Czekster, C.M.
登録日2021-11-17
公開日2022-09-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.093 Å)
主引用文献Active site remodelling of a cyclodipeptide synthase redefines substrate scope.
Commun Chem, 5, 2022
5O3X
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BU of 5o3x by Molmil
Structural characterization of the fast and promiscuous macrocyclase from plant - apo PCY1
分子名称: CACODYLATE ION, Peptide cyclase 1
著者Ludewig, H, Czekster, C.M, Bent, A.F, Naismith, J.H.
登録日2017-05-25
公開日2018-02-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Characterization of the Fast and Promiscuous Macrocyclase from Plant PCY1 Enables the Use of Simple Substrates.
ACS Chem. Biol., 13, 2018
8PQR
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BU of 8pqr by Molmil
Nucleoside 2'deoxyribosyltransferase from Chroococcidiopsis thermalis PCC 7203 WT bound to DAD_Immucillin-H
分子名称: 7-[[(3R,4R)-3-(hydroxymethyl)-4-oxidanyl-pyrrolidin-1-ium-1-yl]methyl]-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one, Nucleoside 2-deoxyribosyltransferase
著者Tang, P, Harding, C.J, Czekster, C.M.
登録日2023-07-11
公開日2024-02-21
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.586 Å)
主引用文献Snapshots of the Reaction Coordinate of a Thermophilic 2'-Deoxyribonucleoside/ribonucleoside Transferase.
Acs Catalysis, 14, 2024

 

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