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5EMV
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BU of 5emv by Molmil
Crystal structure of the palmitoylated human TEAD2 transcription factor
分子名称: Transcriptional enhancer factor TEF-4
著者Noland, C.L, Gierke, S, Schnier, P.D, Murray, J, Sandoval, W.N, Sagolla, M, Dey, A, Hannoush, R.N, Fairbrother, W.J, Cunningham, C.N.
登録日2015-11-06
公開日2015-12-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Palmitoylation of TEAD Transcription Factors Is Required for Their Stability and Function in Hippo Pathway Signaling.
Structure, 24, 2016
5EMW
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BU of 5emw by Molmil
Crystal structure of the palmitoylated human TEAD3 transcription factor
分子名称: CALCIUM ION, Transcriptional enhancer factor TEF-5
著者Noland, C.L, Gierke, S, Schnier, P.D, Murray, J, Sandoval, W.N, Sagolla, M, Dey, A, Hannoush, R.N, Fairbrother, W.J, Cunningham, C.N.
登録日2015-11-06
公開日2015-12-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Palmitoylation of TEAD Transcription Factors Is Required for Their Stability and Function in Hippo Pathway Signaling.
Structure, 24, 2016
6UYC
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BU of 6uyc by Molmil
Crystal structure of TEAD2 bound to Compound 2
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, N-{5-[(E)-2-(4,4-difluorocyclohexyl)ethenyl]-6-methoxypyridin-3-yl}methanesulfonamide, Transcriptional enhancer factor TEF-4
著者Noland, C.L, Holden, J.K, Crawford, J.J, Zbieg, J.R, Cunningham, C.N.
登録日2019-11-12
公開日2020-06-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.658 Å)
主引用文献Small Molecule Dysregulation of TEAD Lipidation Induces a Dominant-Negative Inhibition of Hippo Pathway Signaling.
Cell Rep, 31, 2020
6UYB
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BU of 6uyb by Molmil
Crystal structure of TEAD2 bound to Compound 1
分子名称: (3R,4R)-1-{3-[(E)-2-(4-chlorophenyl)ethenyl]-4-methoxy-5-methylphenyl}-3,4-dihydroxypyrrolidin-2-one, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, ...
著者Noland, C.L, Holden, J.K, Crawford, J.J, Zbieg, J.R, Cunningham, C.N.
登録日2019-11-12
公開日2020-06-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.543 Å)
主引用文献Small Molecule Dysregulation of TEAD Lipidation Induces a Dominant-Negative Inhibition of Hippo Pathway Signaling.
Cell Rep, 31, 2020
5TOF
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BU of 5tof by Molmil
Room temperature structure of ubiquitin variant u7ub25
分子名称: Polyubiquitin-B, SULFATE ION
著者Biel, J.T, Thompson, M.C, Cunningham, C.N, Corn, J.E, Fraser, J.S.
登録日2016-10-17
公開日2017-05-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献Flexibility and Design: Conformational Heterogeneity along the Evolutionary Trajectory of a Redesigned Ubiquitin.
Structure, 25, 2017
5TOG
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BU of 5tog by Molmil
Room temperature structure of ubiquitin variant u7ub25.2540
分子名称: Polyubiquitin-B, SULFATE ION
著者Biel, J.T, Thompson, M.C, Cunningham, C.N, Corn, J.E, Fraser, J.S.
登録日2016-10-17
公開日2017-05-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献Flexibility and Design: Conformational Heterogeneity along the Evolutionary Trajectory of a Redesigned Ubiquitin.
Structure, 25, 2017
2M0X
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BU of 2m0x by Molmil
Solution structure of U14Ub1, an engineered ubiquitin variant with increased affinity for USP14
分子名称: engineered ubiquitin variant
著者Phillips, A.H, Fairbrother, W.J, Corn, J.E.
登録日2012-11-08
公開日2013-06-26
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Conformational dynamics control ubiquitin-deubiquitinase interactions and influence in vivo signaling.
Proc.Natl.Acad.Sci.USA, 110, 2013

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件を2024-10-16に公開中

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