3HPL
 
 | | KcsA E71H-F103A mutant in the closed state | | 分子名称: | Antibody Fab heavy chain, Antibody fab light chain, POTASSIUM ION, ... | | 著者 | Cuello, L.G, Jogini, V, Cortes, D.M, Perozo, E. | | 登録日 | 2009-06-04 | | 公開日 | 2010-06-23 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for the coupling between activation and inactivation gates in K(+) channels.
Nature, 466, 2010
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5VKH
 | | Closed conformation of KcsA Y82A-F103A mutant | | 分子名称: | (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, Antibody Heavy Chain, Antibody Light Chain, ... | | 著者 | Cuello, L.G, Perozo, E, Cortes, D.M. | | 登録日 | 2017-04-21 | | 公開日 | 2017-12-06 | | 最終更新日 | 2020-01-01 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | The gating cycle of a K+ channel at atomic resolution.
Elife, 6, 2017
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5VK6
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5VKE
 | | Open conformation of KcsA deep-inactivated | | 分子名称: | (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, Antibody Heavy Chain, Antibody Light Chain, ... | | 著者 | Cuello, L.G, Perozo, E, Cortes, D.M. | | 登録日 | 2017-04-21 | | 公開日 | 2017-12-06 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | The gating cycle of a K+ channel at atomic resolution.
Elife, 6, 2017
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3FB5
 | | KcsA potassium channel in the partially open state with 14.5 A opening at T112 | | 分子名称: | POTASSIUM ION, Voltage-gated potassium channel, antibody Fab fragment heavy chain, ... | | 著者 | Cuello, L.G, Jogini, V, Cortes, D.M, Perozo, E. | | 登録日 | 2008-11-18 | | 公開日 | 2010-05-19 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | KcsA potassium channel in the partially open state with 14.5 A opening at T112
TO BE PUBLISHED
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3FB6
 | | KcsA Potassium channel in the partially open state with 16 A opening at T112 | | 分子名称: | POTASSIUM ION, Voltage-gated potassium channel, antibody fab fragment heavy chain, ... | | 著者 | Cuello, L.G, Jogini, V, Cortes, D.M, Perozo, E. | | 登録日 | 2008-11-18 | | 公開日 | 2010-05-19 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | KcsA Potassium channel in the partially open state with 16 A opening at T112
TO BE PUBLISHED
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3FB7
 | | Open KcsA potassium channel in the presence of Rb+ ion | | 分子名称: | RUBIDIUM ION, Voltage-gated potassium channel, antibody fab fragment heavy chain, ... | | 著者 | Cuello, L.G, Jogini, V, Cortes, D.M, Pan, A.C, Gagnon, D.H, Cordero-Morales, J.F, Chakrapani, S, Roux, B, Perozo, E. | | 登録日 | 2008-11-18 | | 公開日 | 2010-07-14 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Open KcsA potassium channel in the presence of Rb+ ion
TO BE PUBLISHED
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3F7Y
 | | KcsA Potassium channel in the partially open state with 17 A opening at T112 | | 分子名称: | POTASSIUM ION, Voltage-gated potassium channel, antibody fab fragment heavy chain, ... | | 著者 | Cuello, L.G, Jogini, V, Cortes, D.M, Perozo, E. | | 登録日 | 2008-11-10 | | 公開日 | 2010-05-19 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | KcsA Potassium channel in the partially open state with 17 A opening at T112
TO BE PUBLISHED
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3F5W
 | | KcsA Potassium channel in the open-inactivated state with 32 A opening at T112 | | 分子名称: | Antibody heavy chain, Antibody light chain, POTASSIUM ION, ... | | 著者 | Cuello, L.G, Jogini, V, Cortes, D.M, Perozo, E. | | 登録日 | 2008-11-04 | | 公開日 | 2010-05-19 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | KcsA Potassium channel in the open-inactivated state with 32 A opening at T112
TO BE PUBLISHED
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3FB8
 | | KcsA Potassium channel in the open-conductive state with 20 A opening at T112 in the presence of Rb+ ion | | 分子名称: | RUBIDIUM ION, Voltage-gated potassium channel, antibody fab fragment heavy chain, ... | | 著者 | Cuello, L.G, Jogini, V, Cortes, D.M, Perozo, E. | | 登録日 | 2008-11-18 | | 公開日 | 2010-05-19 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | KcsA Potassium channel in the open-conductive state
with 20 A opening at T112 in the presence of Rb+ ion
TO BE PUBLISHED
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3F7V
 | | KcsA Potassium channel in the open-inactivated state with 23 A opening at T112 | | 分子名称: | POTASSIUM ION, Voltage-gated potassium channel, antibody fab fragment Heavy chain, ... | | 著者 | Cuello, L.G, Jogini, V, Cortes, D.M, Perozo, E. | | 登録日 | 2008-11-10 | | 公開日 | 2010-05-19 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | KcsA Potassium channel in the open-inactivated state with 23 A opening at T112
TO BE PUBLISHED
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6PA0
 | | Structure of the G77A mutant in Sodium Chloride | | 分子名称: | Antibody HEAVY fragment, Antibody LIGHT fragment, DIACYL GLYCEROL, ... | | 著者 | Cuello, L.G, Guan, L. | | 登録日 | 2019-06-11 | | 公開日 | 2019-08-07 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structure, function, and ion-binding properties of a K+channel stabilized in the 2,4-ion-bound configuration.
Proc.Natl.Acad.Sci.USA, 116, 2019
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7SQW
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2ATK
 | | Structure of a mutant KcsA K+ channel | | 分子名称: | ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, NONAN-1-OL, ... | | 著者 | Cordero-Morales, J.F, Cuello, L.G, Zhao, Y, Jogini, V, Chakrapani, S, Roux, B, Perozo, E. | | 登録日 | 2005-08-25 | | 公開日 | 2006-03-07 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Molecular determinants of gating at the potassium-channel selectivity filter.
Nat.Struct.Mol.Biol., 13, 2006
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1ZWI
 | | Structure of mutant KcsA potassium channel | | 分子名称: | DIACYL GLYCEROL, NONAN-1-OL, POTASSIUM ION, ... | | 著者 | Cordero-Morales, J.F, Cuello, L.G, Zhao, Y, Jogini, V, Cortes, D.M, Roux, B, Perozo, E. | | 登録日 | 2005-06-03 | | 公開日 | 2006-03-07 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Molecular determinants of gating at the potassium-channel selectivity filter.
Nat.Struct.Mol.Biol., 13, 2006
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3PJS
 | | Mechanism of Activation Gating in the Full-Length KcsA K+ Channel | | 分子名称: | FAB heavy chain, FAB light chain, Voltage-gated potassium channel | | 著者 | Uysal, S, Cuello, L.G, Kossiakoff, A, Perozo, E. | | 登録日 | 2010-11-10 | | 公開日 | 2011-07-06 | | 最終更新日 | 2011-08-03 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Mechanism of activation gating in the full-length KcsA K+ channel.
Proc.Natl.Acad.Sci.USA, 108, 2011
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6BY3
 | | Open and conductive conformation of KcsA-T75A mutant | | 分子名称: | Antibody Heavy Chain, Antibody Light Chain, DIACYL GLYCEROL, ... | | 著者 | Labro, A.J, Cortes, D.M, Tilegenova, C, Cuello, L.G. | | 登録日 | 2017-12-19 | | 公開日 | 2018-05-09 | | 最終更新日 | 2020-01-01 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | Inverted allosteric coupling between activation and inactivation gates in K+channels.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6BY2
 | | Closed and deep-inactivated conformation of KcsA-T75A mutant | | 分子名称: | Antibody Heavy Chain, Antibody Light Chain, DIACYL GLYCEROL, ... | | 著者 | Labro, A.J, Cortes, D.M, Tilegenova, C, Cuello, L.G. | | 登録日 | 2017-12-19 | | 公開日 | 2018-05-09 | | 最終更新日 | 2020-01-01 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Inverted allosteric coupling between activation and inactivation gates in K+channels.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6NFV
 | | Structure of the KcsA-G77C mutant or the 2,4-ion bound configuration of a K+ channel selectivity filter. | | 分子名称: | (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, NONAN-1-OL, POTASSIUM ION, ... | | 著者 | Tilegenova, C, Cortes, D.M, Jahovic, N, Hardy, E, Parameswaran, H, Guan, L, Cuello, L.G. | | 登録日 | 2018-12-20 | | 公開日 | 2019-08-07 | | 最終更新日 | 2019-12-18 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | Structure, function, and ion-binding properties of a K+channel stabilized in the 2,4-ion-bound configuration.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6NFU
 | | Structure of the KcsA-G77A mutant or the 2,4-ion bound configuration of a K+ channel selectivity filter. | | 分子名称: | (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, NONAN-1-OL, POTASSIUM ION, ... | | 著者 | Tilegenova, C, Cortes, D.M, Jahovic, N, Hardy, E, Parameswaran, H, Guan, L, Cuello, L.G. | | 登録日 | 2018-12-20 | | 公開日 | 2019-08-07 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Structure, function, and ion-binding properties of a K+channel stabilized in the 2,4-ion-bound configuration.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6HJY
 | | X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) Delta8 truncation mutant in complex with nanobody 72 | | 分子名称: | Cys-loop ligand-gated ion channel, nanobody 72 | | 著者 | Spurny, R, Govaerts, C, Evans, G.L, Pardon, E, Steyaert, J, Ulens, C. | | 登録日 | 2018-09-04 | | 公開日 | 2019-10-09 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | | 主引用文献 | A lipid site shapes the agonist response of a pentameric ligand-gated ion channel.
Nat.Chem.Biol., 15, 2019
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1F6G
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6HK0
 | | X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) F16'S pore mutant (F247S) with alternate M4 conformation. | | 分子名称: | Cys-loop ligand-gated ion channel, DODECYL-BETA-D-MALTOSIDE | | 著者 | Nury, H, Spurny, R, Govaerts, C, Evans, G.L, Pardon, E, Steyaert, J, Ulens, C. | | 登録日 | 2018-09-04 | | 公開日 | 2019-10-09 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | | 主引用文献 | A lipid site shapes the agonist response of a pentameric ligand-gated ion channel.
Nat.Chem.Biol., 15, 2019
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6HJX
 | | X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) 7'C pore mutant (L238C) in complex with nanobody 72 | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cys-loop ligand-gated ion channel, DODECYL-BETA-D-MALTOSIDE, ... | | 著者 | Spurny, R, Govaerts, C, Evans, G.L, Pardon, E, Steyaert, J, Ulens, C. | | 登録日 | 2018-09-04 | | 公開日 | 2019-10-09 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A lipid site shapes the agonist response of a pentameric ligand-gated ion channel.
Nat.Chem.Biol., 15, 2019
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4LMK
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