8PRK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8prk by Molmil](/molmil-images/mine/8prk) | THE R78K AND D117E ACTIVE SITE VARIANTS OF SACCHAROMYCES CEREVISIAE SOLUBLE INORGANIC PYROPHOSPHATASE: STRUCTURAL STUDIES AND MECHANISTIC IMPLICATIONS | 分子名称: | MANGANESE (II) ION, PHOSPHATE ION, PROTEIN (INORGANIC PYROPHOSPHATASE) | 著者 | Tuominen, V, Heikinheimo, P, Kajander, T, Torkkel, T, Hyytia, T, Kapyla, J, Lahti, R, Cooperman, B.S, Goldman, A. | 登録日 | 1998-09-16 | 公開日 | 1998-12-23 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | The R78K and D117E active-site variants of Saccharomyces cerevisiae soluble inorganic pyrophosphatase: structural studies and mechanistic implications. J.Mol.Biol., 284, 1998
|
|
117E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 117e by Molmil](/molmil-images/mine/117e) | THE R78K AND D117E ACTIVE SITE VARIANTS OF SACCHAROMYCES CEREVISIAE SOLUBLE INORGANIC PYROPHOSPHATASE: STRUCTURAL STUDIES AND MECHANISTIC IMPLICATIONS | 分子名称: | MANGANESE (II) ION, PHOSPHATE ION, PROTEIN (INORGANIC PYROPHOSPHATASE) | 著者 | Tuominen, V, Heikinheimo, P, Kajander, T, Torkkel, T, Hyytia, T, Kapyla, J, Lahti, R, Cooperman, B.S, Goldman, A. | 登録日 | 1998-09-15 | 公開日 | 1998-12-23 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | The R78K and D117E active-site variants of Saccharomyces cerevisiae soluble inorganic pyrophosphatase: structural studies and mechanistic implications. J.Mol.Biol., 284, 1998
|
|
1AFT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1aft by Molmil](/molmil-images/mine/1aft) | SMALL SUBUNIT C-TERMINAL INHIBITORY PEPTIDE OF MOUSE RIBONUCLEOTIDE REDUCTASE AS BOUND TO THE LARGE SUBUNIT, NMR, 26 STRUCTURES | 分子名称: | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE | 著者 | Laub, P.B, Fisher, A.L, Furst, G.T, Barwis, B.A, Hamann, C.S, Cooperman, B.S. | 登録日 | 1997-03-13 | 公開日 | 1997-05-15 | 最終更新日 | 2017-11-29 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure of an inhibitory R2 C-terminal peptide bound to mouse ribonucleotide reductase R1 subunit. Nat.Struct.Biol., 2, 1995
|
|
2ZLF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zlf by Molmil](/molmil-images/mine/2zlf) | The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase | 分子名称: | FTLDADF, Ribonucleoside-diphosphate reductase large chain 1 | 著者 | Xu, H, Fairman, J.W, Wijerathna, S.R, LaMacchia, J, Kreischer, N.R, Helmbrecht, E, Cooperman, B.S, Dealwis, C. | 登録日 | 2008-04-09 | 公開日 | 2008-08-19 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase: A Conformationally Flexible Pharmacophore J.Med.Chem., 51, 2008
|
|
2ZLG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zlg by Molmil](/molmil-images/mine/2zlg) | The Structual Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase | 分子名称: | (5R,9S,12S,15S,18S,21S)-21-benzyl-12,18-bis(carboxymethyl)-15-cyclohexyl-1-(9H-fluoren-9-yl)-4-methyl-9-(2-methylpropyl)-3,6,10,13,16,19-hexaoxo-5-phenyl-2-oxa-4,8,11,14,17,20-hexaazadocosan-22-oic acid, GLYCEROL, Ribonucleoside-diphosphate reductase large chain 1 | 著者 | Xu, H, Fairman, J.W, Wijerathna, S.R, LaMacchia, J, Kreischer, N.R, Helmbrecht, E, Cooperman, B.S, Dealwis, C. | 登録日 | 2008-04-09 | 公開日 | 2008-08-19 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase: A Conformationally Flexible Pharmacophore J.Med.Chem., 51, 2008
|
|
1HUJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1huj by Molmil](/molmil-images/mine/1huj) | |
1HUK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1huk by Molmil](/molmil-images/mine/1huk) | |
1E9G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1e9g by Molmil](/molmil-images/mine/1e9g) | STRUCTURE OF INORGANIC PYROPHOSPHATASE | 分子名称: | INORGANIC PYROPHOSPHATASE, MANGANESE (II) ION, PHOSPHATE ION | 著者 | Heikinheimo, P, Tuominen, V, Ahonen, A.-K, Teplyakov, A, Cooperman, B.S, Baykov, A.A, Lahti, R, Goldman, A. | 登録日 | 2000-10-12 | 公開日 | 2001-03-19 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Toward a Quantum-Mechanical Description of Metal-Assisted Phosphoryl Transfer in Pyrophosphatase Proc.Natl.Acad.Sci.USA, 98, 2001
|
|
1E6A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1e6a by Molmil](/molmil-images/mine/1e6a) | Fluoride-inhibited substrate complex of Saccharomyces cerevisiae inorganic pyrophosphatase | 分子名称: | FLUORIDE ION, INORGANIC PYROPHOSPHATASE, MANGANESE (II) ION, ... | 著者 | Heikinheimo, P, Tuominen, V, Ahonen, A.-K, Teplyakov, A, Cooperman, B.S, Baykov, A.A, Lahti, R, Goldman, A. | 登録日 | 2000-08-09 | 公開日 | 2001-03-19 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Toward a quantum-mechanical description of metal-assisted phosphoryl transfer in pyrophosphatase. Proc. Natl. Acad. Sci. U.S.A., 98, 2001
|
|
1FOZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1foz by Molmil](/molmil-images/mine/1foz) | STRUCTURE OF CYCLIC PEPTIDE INHIBITORS OF MAMMALIAN RIBONUCLEOTIDE REDUCTASE | 分子名称: | SYNTHETIC CYCLIC PEPTIDE | 著者 | Pellegrini, M, Liehr, S, Fisher, A.L, Cooperman, B.S, Mierke, D.F. | 登録日 | 2000-08-29 | 公開日 | 2000-11-22 | 最終更新日 | 2011-07-13 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure-based optimization of peptide inhibitors of mammalian ribonucleotide reductase. Biochemistry, 39, 2000
|
|
1IPW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ipw by Molmil](/molmil-images/mine/1ipw) | |
2EIP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2eip by Molmil](/molmil-images/mine/2eip) | |
1FAJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1faj by Molmil](/molmil-images/mine/1faj) | |
1YPP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ypp by Molmil](/molmil-images/mine/1ypp) | ACID ANHYDRIDE HYDROLASE | 分子名称: | INORGANIC PYROPHOSPHATASE, MANGANESE (II) ION, PHOSPHATE ION | 著者 | Harutyunyan, E.H, Kuranova, I.P, Lamzin, V.S, Dauter, Z, Wilson, K.S. | 登録日 | 1996-05-29 | 公開日 | 1996-12-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | X-ray structure of yeast inorganic pyrophosphatase complexed with manganese and phosphate. Eur.J.Biochem., 239, 1996
|
|
1WGI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1wgi by Molmil](/molmil-images/mine/1wgi) | |
1WGJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1wgj by Molmil](/molmil-images/mine/1wgj) | |
6EZE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6eze by Molmil](/molmil-images/mine/6eze) | The open conformation of E.coli Elongation Factor Tu in complex with GDPNP. | 分子名称: | DI(HYDROXYETHYL)ETHER, Elongation factor Tu 2, GLYCEROL, ... | 著者 | Johansen, J.S, Blaise, M, Thirup, S.S. | 登録日 | 2017-11-15 | 公開日 | 2018-08-22 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | E. coli elongation factor Tu bound to a GTP analogue displays an open conformation equivalent to the GDP-bound form. Nucleic Acids Res., 46, 2018
|
|
1AS4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1as4 by Molmil](/molmil-images/mine/1as4) | CLEAVED ANTICHYMOTRYPSIN A349R | 分子名称: | ACETATE ION, ANTICHYMOTRYPSIN | 著者 | Lukacs, C.M, Christianson, D.W. | 登録日 | 1997-08-12 | 公開日 | 1998-02-25 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Engineering an anion-binding cavity in antichymotrypsin modulates the "spring-loaded" serpin-protease interaction. Biochemistry, 37, 1998
|
|