5TGJ
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5TGI
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6E8R
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8TXY
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![BU of 8txy by Molmil](/molmil-images/mine/8txy) | X-ray crystal structure of JRD-SIK1/2i-3 bound to a MARK2-SIK2 chimera | 分子名称: | DI(HYDROXYETHYL)ETHER, N-[(5P,8R)-5-(2-cyano-5-{[(3R)-1-methylpyrrolidin-3-yl]methoxy}pyridin-4-yl)pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide, SULFATE ION, ... | 著者 | Raymond, D.D, Lemke, C.T, Shaffer, P.L, Collins, B, Steele, R, Seierstad, M. | 登録日 | 2023-08-24 | 公開日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Identification of highly selective SIK1/2 inhibitors that modulate innate immune activation and suppress intestinal inflammation. Proc.Natl.Acad.Sci.USA, 121, 2024
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5E7F
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![BU of 5e7f by Molmil](/molmil-images/mine/5e7f) | Complex between lactococcal phage Tuc2009 RBP head domain and a nanobody (L06) | 分子名称: | Major structural protein 1, nanobody L06 | 著者 | Legrand, P, Collins, B, Blangy, S, Murphy, J, Spinelli, S, Gutierrez, C, Richet, N, Kellenberger, C, Desmyter, A, Mahony, J, van Sinderen, D, Cambillau, C. | 登録日 | 2015-10-12 | 公開日 | 2015-12-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The Atomic Structure of the Phage Tuc2009 Baseplate Tripod Suggests that Host Recognition Involves Two Different Carbohydrate Binding Modules. Mbio, 7, 2016
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5E7T
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![BU of 5e7t by Molmil](/molmil-images/mine/5e7t) | Structure of the tripod (BppUct-A-L) from the baseplate of bacteriophage Tuc2009 | 分子名称: | CALCIUM ION, Major structural protein 1, Minor structural protein 4, ... | 著者 | Legrand, P, Collins, B, Blangy, S, Murphy, J, Spinelli, S, Gutierrez, C, Richet, N, Kellenberger, C, Desmyter, A, Mahony, J, van Sinderen, D, Cambillau, C. | 登録日 | 2015-10-13 | 公開日 | 2015-12-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | The Atomic Structure of the Phage Tuc2009 Baseplate Tripod Suggests that Host Recognition Involves Two Different Carbohydrate Binding Modules. Mbio, 7, 2016
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5E7B
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![BU of 5e7b by Molmil](/molmil-images/mine/5e7b) | Structure of a nanobody (vHH) from camel against phage Tuc2009 RBP (BppL, ORF53) | 分子名称: | nanobody nano-L06 | 著者 | Legrand, P, Collins, B, Blangy, S, Murphy, J, Spinelli, S, Gutierrez, C, Richet, N, Kellenberger, C, Desmyter, A, Mahony, J, van Sinderen, D, Cambillau, C. | 登録日 | 2015-10-12 | 公開日 | 2015-12-30 | 最終更新日 | 2016-05-04 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | The Atomic Structure of the Phage Tuc2009 Baseplate Tripod Suggests that Host Recognition Involves Two Different Carbohydrate Binding Modules. Mbio, 7, 2016
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3PSN
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![BU of 3psn by Molmil](/molmil-images/mine/3psn) | Crystal structure of mouse VPS29 complexed with Mn2+ | 分子名称: | MANGANESE (II) ION, Vacuolar protein sorting-associated protein 29 | 著者 | Swarbrick, J, Shaw, D, Chhabra, S, Ghai, R, Valkov, E, Norwood, S, Collins, B. | 登録日 | 2010-12-02 | 公開日 | 2010-12-15 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Conformational dynamics and biomolecular interactions of VPS29 studied by NMR and X-ray crystallography To be Published
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3PSO
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![BU of 3pso by Molmil](/molmil-images/mine/3pso) | Crystal structure of mouse VPS29 complexed with Zn2+ | 分子名称: | Vacuolar protein sorting-associated protein 29, ZINC ION | 著者 | Swarbrick, J, Shaw, D, Chhabra, S, Ghai, R, Valkov, E, Norwood, S, Collins, B. | 登録日 | 2010-12-02 | 公開日 | 2010-12-15 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Conformational dynamics and biomolecular interactions of VPS29 studied by NMR and X-ray crystallography To be Published
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3KEC
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![BU of 3kec by Molmil](/molmil-images/mine/3kec) | Crystal Structure of Human MMP-13 complexed with a phenyl-2H-tetrazole compound | 分子名称: | 4-{[({3-[2-(4-methoxybenzyl)-2H-tetrazol-5-yl]phenyl}carbonyl)amino]methyl}benzoic acid, ACETOHYDROXAMIC ACID, CALCIUM ION, ... | 著者 | Shieh, H.-S, Pavlovsky, A.G, Collins, B, Schnute, M.E. | 登録日 | 2009-10-25 | 公開日 | 2010-11-10 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis. Bioorg.Med.Chem.Lett., 20, 2010
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3KEK
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![BU of 3kek by Molmil](/molmil-images/mine/3kek) | Crystal Structure of Human MMP-13 complexed with a (pyridin-4-yl)-2H-tetrazole compound | 分子名称: | CALCIUM ION, Collagenase 3, ZINC ION, ... | 著者 | Shieh, H.-S, Collins, B, Schnute, M.E. | 登録日 | 2009-10-26 | 公開日 | 2010-11-10 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis. Bioorg.Med.Chem.Lett., 20, 2009
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3KEJ
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![BU of 3kej by Molmil](/molmil-images/mine/3kej) | Crystal Structure of Human MMP-13 complexed with a (pyridin-4-yl)-2H-tetrazole compound | 分子名称: | 4-[(5-{2-[(3-fluorobenzyl)carbamoyl]pyridin-4-yl}-2H-tetrazol-2-yl)methyl]benzoic acid, CALCIUM ION, Collagenase 3, ... | 著者 | Shieh, H.-S, Collins, B, Schnute, M.E. | 登録日 | 2009-10-26 | 公開日 | 2010-11-10 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis. Bioorg.Med.Chem.Lett., 20, 2010
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6N5X
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![BU of 6n5x by Molmil](/molmil-images/mine/6n5x) | Crystal structure of the SNX5 PX domain in complex with the CI-MPR (space group P212121 - Form 1) | 分子名称: | GLYCEROL, O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500), Sorting nexin-5,Cation-independent mannose-6-phosphate receptor | 著者 | Collins, B, Paul, B, Weeratunga, S. | 登録日 | 2018-11-22 | 公開日 | 2019-09-18 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.051 Å) | 主引用文献 | Molecular identification of a BAR domain-containing coat complex for endosomal recycling of transmembrane proteins. Nat.Cell Biol., 21, 2019
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6N5Z
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6N5Y
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5TGH
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4QDH
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3LH9
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3LH8
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3LHA
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5BOT
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5BOY
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8FUD
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4PQP
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![BU of 4pqp by Molmil](/molmil-images/mine/4pqp) | Crystal structure of human SNX14 PX domain in space group P43212 | 分子名称: | GLYCEROL, Sorting nexin-14 | 著者 | Mas, C, Norwood, S, Bugarcic, A, Kinna, G, Leneva, N, Kovtun, O, Teasdale, R, Collins, B. | 登録日 | 2014-03-03 | 公開日 | 2014-09-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling. J.Biol.Chem., 289, 2014
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4P2A
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![BU of 4p2a by Molmil](/molmil-images/mine/4p2a) | Structure of mouse VPS26A bound to rat SNX27 PDZ domain | 分子名称: | MERCURY (II) ION, Sorting nexin-27, Vacuolar protein sorting-associated protein 26A | 著者 | Clairfeuille, T, Gallon, M, Mas, C, Ghai, R, Teasdale, R, Cullen, P, Collins, B. | 登録日 | 2014-03-03 | 公開日 | 2014-09-03 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | A unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer. Proc.Natl.Acad.Sci.USA, 111, 2014
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