6F9N
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![BU of 6f9n by Molmil](/molmil-images/mine/6f9n) | CRYSTAL STRUCTURE OF THE HUMAN CPSF160-WDR33 COMPLEX | 分子名称: | Cleavage and polyadenylation specificity factor subunit 1, pre-mRNA 3' end processing protein WDR33 | 著者 | Clerici, M, Jinek, M. | 登録日 | 2017-12-14 | 公開日 | 2018-01-03 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural insights into the assembly and polyA signal recognition mechanism of the human CPSF complex. Elife, 6, 2017
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6FUW
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![BU of 6fuw by Molmil](/molmil-images/mine/6fuw) | Cryo-EM structure of the human CPSF160-WDR33-CPSF30 complex bound to the PAS AAUAAA motif at 3.1 Angstrom resolution | 分子名称: | Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 4, RNA (5'-R(P*AP*AP*UP*AP*AP*AP*GP*G)-3'), ... | 著者 | Clerici, M, Faini, M, Jinek, M. | 登録日 | 2018-02-28 | 公開日 | 2018-03-21 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | 主引用文献 | Structural basis of AAUAAA polyadenylation signal recognition by the human CPSF complex. Nat. Struct. Mol. Biol., 25, 2018
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4CEM
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![BU of 4cem by Molmil](/molmil-images/mine/4cem) | Crystal structure of the first MIF4G domain of human nonsense mediated decay factor UPF2 | 分子名称: | REGULATOR OF NONSENSE TRANSCRIPTS 2 | 著者 | Clerici, M, Deniaud, A, Boehm, V, Gehring, N.H, Schaffitzel, C, Cusack, S. | 登録日 | 2013-11-11 | 公開日 | 2013-12-11 | 最終更新日 | 2014-03-12 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural and Functional Analysis of the Three Mif4G Domains of Nonsense-Mediated Decay Factor Upf2. Nucleic Acids Res., 42, 2014
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4CEK
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![BU of 4cek by Molmil](/molmil-images/mine/4cek) | Crystal structure of the second MIF4G domain of human nonsense mediated decay factor UPF2 | 分子名称: | REGULATOR OF NONSENSE TRANSCRIPTS 2 | 著者 | Clerici, M, Deniaud, A, Boehm, V, Gehring, N.H, Schaffitzel, C, Cusack, S. | 登録日 | 2013-11-11 | 公開日 | 2013-12-11 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural and Functional Analysis of the Three Mif4G Domains of Nonsense-Mediated Decay Factor Upf2. Nucleic Acids Res., 42, 2014
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2WJY
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![BU of 2wjy by Molmil](/molmil-images/mine/2wjy) | Crystal structure of the complex between human nonsense mediated decay factors UPF1 and UPF2 Orthorhombic form | 分子名称: | REGULATOR OF NONSENSE TRANSCRIPTS 1, SULFATE ION, ZINC ION | 著者 | Clerici, M, Mourao, A, Gutsche, I, Gehring, N.H, Hentze, M.W, Kulozik, A, Kadlec, J, Sattler, M, Cusack, S. | 登録日 | 2009-06-01 | 公開日 | 2009-07-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Unusual Bipartite Mode of Interaction between the Nonsense-Mediated Decay Factors, Upf1 and Upf2. Embo J., 28, 2009
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2WJV
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![BU of 2wjv by Molmil](/molmil-images/mine/2wjv) | Crystal structure of the complex between human nonsense mediated decay factors UPF1 and UPF2 | 分子名称: | REGULATOR OF NONSENSE TRANSCRIPTS 1, REGULATOR OF NONSENSE TRANSCRIPTS 2, SULFATE ION, ... | 著者 | Clerici, M, Mourao, A, Gutsche, I, Gehring, N.H, Hentze, M.W, Kulozik, A, Kadlec, J, Sattler, M, Cusack, S. | 登録日 | 2009-06-01 | 公開日 | 2009-07-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Unusual Bipartite Mode of Interaction between the Nonsense-Mediated Decay Factors, Upf1 and Upf2. Embo J., 28, 2009
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5L8H
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![BU of 5l8h by Molmil](/molmil-images/mine/5l8h) | Structure of USP46-UbVME | 分子名称: | Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 46, ZINC ION | 著者 | Clerici, M, Sixma, T, Dharadhar, S. | 登録日 | 2016-06-07 | 公開日 | 2016-09-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | A conserved two-step binding for the UAF1 regulator to the USP12 deubiquitinating enzyme. J.Struct.Biol., 196, 2016
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7ZYH
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![BU of 7zyh by Molmil](/molmil-images/mine/7zyh) | Crystal structure of human CPSF30 in complex with hFip1 | 分子名称: | Cleavage and polyadenylation specificity factor subunit 4, Isoform 4 of Pre-mRNA 3'-end-processing factor FIP1, ZINC ION | 著者 | Muckenfuss, L.M, Jinek, M, Migenda Herranz, A.C, Clerici, M. | 登録日 | 2022-05-24 | 公開日 | 2022-09-14 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Fip1 is a multivalent interaction scaffold for processing factors in human mRNA 3' end biogenesis. Elife, 11, 2022
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2Y6E
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![BU of 2y6e by Molmil](/molmil-images/mine/2y6e) | Structure of the D1D2 domain of USP4, the conserved catalytic domain | 分子名称: | SULFATE ION, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 4, ZINC ION | 著者 | Luna-Vargas, M.P.A, Faesen, A.C, van Dijk, W.J, Rape, M, Fish, A, Sixma, T.K. | 登録日 | 2011-01-20 | 公開日 | 2011-04-06 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The Dusp-Ubl Domain of Usp4 Enhances its Catalytic Efficiency by Promoting Ubiquitin Exchange. Nat.Commun., 5, 2014
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6AQR
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![BU of 6aqr by Molmil](/molmil-images/mine/6aqr) | SAGA DUB module Ubp8(C146A)/Sgf11/Sus1/Sgf73 bound to monoubiquitin | 分子名称: | Polyubiquitin-C, SAGA-associated factor 11, SAGA-associated factor 73, ... | 著者 | Morrow, M.E, Morgan, M.T, Wolberger, C. | 登録日 | 2017-08-21 | 公開日 | 2018-07-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Active site alanine mutations convert deubiquitinases into high-affinity ubiquitin-binding proteins. EMBO Rep., 19, 2018
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7ZY4
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![BU of 7zy4 by Molmil](/molmil-images/mine/7zy4) | |
5L8W
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![BU of 5l8w by Molmil](/molmil-images/mine/5l8w) | Structure of USP12-UB-PRG/UAF1 | 分子名称: | GLYCEROL, Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 12, ... | 著者 | Dharadhar, S, Sixma, T. | 登録日 | 2016-06-08 | 公開日 | 2016-09-28 | 最終更新日 | 2016-11-30 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | A conserved two-step binding for the UAF1 regulator to the USP12 deubiquitinating enzyme. J.Struct.Biol., 196, 2016
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5L8E
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![BU of 5l8e by Molmil](/molmil-images/mine/5l8e) | Structure of UAF1 | 分子名称: | GLYCEROL, Unknown, WD repeat-containing protein 48 | 著者 | Dharadhar, S, Sixma, T. | 登録日 | 2016-06-07 | 公開日 | 2016-09-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A conserved two-step binding for the UAF1 regulator to the USP12 deubiquitinating enzyme. J.Struct.Biol., 196, 2016
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2XR6
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![BU of 2xr6 by Molmil](/molmil-images/mine/2xr6) | Crystal structure of the complex of the carbohydrate recognition domain of human DC-SIGN with pseudo trimannoside mimic. | 分子名称: | 2-AZIDOETHANOL, CALCIUM ION, CD209 ANTIGEN, ... | 著者 | Thepaut, M, Suitkeviciute, I, Sattin, S, Reina, J, Bernardi, A, Fieschi, F. | 登録日 | 2010-09-10 | 公開日 | 2011-10-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Unique Dc-Sign Clustering Activity of a Small Glycomimetic: A Lesson for Ligand Design. Acs Chem.Biol., 9, 2014
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