8SM1
 
 | | CRYSTAL STRUCTURE OF HUMAN ANTIBODY 769A9 IN COMPLEX WITH EPSTEIN-BARR VIRUS MAJOR GLYCOPROTEIN GP350 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 769A9 Fab heavy chain, 769A9 Fab light chain, ... | | 著者 | Chen, W.-H, Bu, W, Cohen, J.I, Kanekiyo, M, Joyce, M.G. | | 登録日 | 2023-04-25 | | 公開日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (3.29 Å) | | 主引用文献 | Structural Basis For Receptor Engagement And Virus Neutralization Through Epstein-Barr Virus Gp350
To Be Published
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8SM0
 | | Crystal structure of human complement receptor 2 (CD21) in complex with Epstein-Barr virus major glycoprotein gp350 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement receptor type 2, Envelope glycoprotein gp350, ... | | 著者 | Chen, W.-H, Bu, W, Cohen, J.I, Kanekiyo, M, Joyce, M.G. | | 登録日 | 2023-04-25 | | 公開日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Structural Basis For Receptor Engagement And Virus Neutralization Through Epstein-Barr Virus Gp350
To Be Published
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7S83
 | | Crystal structure of SARS CoV-2 Spike Receptor Binding Domain in complex with shark neutralizing VNARs ShAb01 and ShAb02 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ShAb01 VNAR, ... | | 著者 | Chen, W.-H, Hajduczki, A, Dooley, H.M, Joyce, M.G. | | 登録日 | 2021-09-17 | | 公開日 | 2022-11-23 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | | 主引用文献 | Shark nanobodies with potent SARS-CoV-2 neutralizing activity and broad sarbecovirus reactivity.
Nat Commun, 14, 2023
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6U6O
 | | Crystal structure of a vaccine-elicited anti-HIV-1 rhesus macaque antibody DH846 | | 分子名称: | DH846 Fab heavy chain, DH846 Fab light chain | | 著者 | Chen, W.-H, Choe, M, Saunders, K.O, Joyce, M.G. | | 登録日 | 2019-08-30 | | 公開日 | 2021-03-24 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.806 Å) | | 主引用文献 | Structural and genetic convergence of HIV-1 neutralizing antibodies in vaccinated non-human primates.
Plos Pathog., 17, 2021
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6U6M
 | | Crystal structure of a vaccine-elicited anti-HIV-1 rhesus macaque antibody DH840.1 | | 分子名称: | DH840.1 Fab heavy chain, DH840.1 Fab light chain | | 著者 | Chen, W.-H, Choe, M, Saunders, K.O, Joyce, M.G. | | 登録日 | 2019-08-30 | | 公開日 | 2021-03-24 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.683 Å) | | 主引用文献 | Structural and genetic convergence of HIV-1 neutralizing antibodies in vaccinated non-human primates.
Plos Pathog., 17, 2021
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7S0J
 | | Crystal structure of Epstein-Barr virus gH/gL targeting antibody 769B10 | | 分子名称: | 769B10 Fab Heavy chain, 769B10 Fab Light chain, GLYCEROL | | 著者 | Chen, W.-H, Kanekiyo, M, Cohen, J.I, Joyce, M.G. | | 登録日 | 2021-08-30 | | 公開日 | 2022-11-09 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Epstein-Barr virus gH/gL has multiple sites of vulnerability for virus neutralization and fusion inhibition.
Immunity, 55, 2022
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7S08
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7S1B
 | | Crystal structure of Epstein-Barr virus glycoproteins gH/gL/gp42-peptide in complex with human neutralizing antibodies 769C2 and 770F7 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 769C2 Fab heavy chain, 769C2 Fab light chain, ... | | 著者 | Chen, W.-H, Cohen, J.I, Kanekiyo, M, Joyce, M.G. | | 登録日 | 2021-09-02 | | 公開日 | 2022-11-09 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | | 主引用文献 | Epstein-Barr virus gH/gL has multiple sites of vulnerability for virus neutralization and fusion inhibition.
Immunity, 55, 2022
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7S07
 | | Crystal structure of Epstein-Barr virus glycoprotein gH/gL/gp42-peptide in complex with human neutralizing antibodies 769B10 and 769C2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 769B10 Fab heavy chain, 769B10 Fab light chain, ... | | 著者 | Chen, W.-H, Kanekiyo, M, Cohen, J.I, Joyce, M.G. | | 登録日 | 2021-08-30 | | 公開日 | 2022-11-09 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.29 Å) | | 主引用文献 | Epstein-Barr virus gH/gL has multiple sites of vulnerability for virus neutralization and fusion inhibition.
Immunity, 55, 2022
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5ISX
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5ISW
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2ZYD
 | | Dimeric 6-phosphogluconate dehydrogenase complexed with glucose | | 分子名称: | 6-phosphogluconate dehydrogenase, decarboxylating, D-glucose | | 著者 | Chen, Y.-Y, Ko, T.-P, Lo, L.-P, Lin, C.-H, Wang, A.H.-J. | | 登録日 | 2009-01-19 | | 公開日 | 2009-09-01 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Conformational changes associated with cofactor/substrate binding of 6-phosphogluconate dehydrogenase from Escherichia coli and Klebsiella pneumoniae: Implications for enzyme mechanism
J.Struct.Biol., 169, 2010
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2ZYG
 | | Apo-form of dimeric 6-phosphogluconate dehydrogenase | | 分子名称: | 6-phosphogluconate dehydrogenase, decarboxylating | | 著者 | Chen, Y.-Y, Ko, T.-P, Lo, L.-P, Lin, C.-H, Wang, A.H.-J. | | 登録日 | 2009-01-21 | | 公開日 | 2009-09-01 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Conformational changes associated with cofactor/substrate binding of 6-phosphogluconate dehydrogenase from Escherichia coli and Klebsiella pneumoniae: Implications for enzyme mechanism
J.Struct.Biol., 169, 2010
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2ZYA
 | | Dimeric 6-phosphogluconate dehydrogenase complexed with 6-phosphogluconate | | 分子名称: | 6-PHOSPHOGLUCONIC ACID, 6-phosphogluconate dehydrogenase, decarboxylating | | 著者 | Chen, Y.-Y, Ko, T.-P, Lo, L.-P, Lin, C.-H, Wang, A.H.-J. | | 登録日 | 2009-01-19 | | 公開日 | 2009-09-01 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Conformational changes associated with cofactor/substrate binding of 6-phosphogluconate dehydrogenase from Escherichia coli and Klebsiella pneumoniae: Implications for enzyme mechanism
J.Struct.Biol., 169, 2010
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3FWN
 | | Dimeric 6-phosphogluconate dehydrogenase complexed with 6-phosphogluconate and 2'-monophosphoadenosine-5'-diphosphate | | 分子名称: | 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, 6-PHOSPHOGLUCONIC ACID, 6-phosphogluconate dehydrogenase, ... | | 著者 | Chen, Y.-Y, Ko, T.-P, Lo, L.-P, Lin, C.-H, Wang, A.H.-J. | | 登録日 | 2009-01-19 | | 公開日 | 2009-09-01 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Conformational changes associated with cofactor/substrate binding of 6-phosphogluconate dehydrogenase from Escherichia coli and Klebsiella pneumoniae: Implications for enzyme mechanism
J.Struct.Biol., 169, 2010
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3PID
 | | The apo-form UDP-glucose 6-dehydrogenase with a C-terminal six-histidine tag | | 分子名称: | UDP-glucose 6-dehydrogenase | | 著者 | Chen, Y.-Y, Ko, T.-P, Lin, C.-H, Chen, W.-H, Wang, A.H.-J. | | 登録日 | 2010-11-06 | | 公開日 | 2011-09-28 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Conformational change upon product binding to Klebsiella pneumoniae UDP-glucose dehydrogenase: a possible inhibition mechanism for the key enzyme in polymyxin resistance.
J.Struct.Biol., 175, 2011
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3PJG
 | | Crystal structure of UDP-glucose dehydrogenase from Klebsiella pneumoniae complexed with product UDP-glucuronic acid | | 分子名称: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, UDP-glucose 6-dehydrogenase, URIDINE-5'-DIPHOSPHATE-GLUCURONIC ACID | | 著者 | Chen, Y.-Y, Ko, T.-P, Lin, C.-H, Chen, W.-H, Wang, A.H.-J. | | 登録日 | 2010-11-10 | | 公開日 | 2011-09-28 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Conformational change upon product binding to Klebsiella pneumoniae UDP-glucose dehydrogenase: a possible inhibition mechanism for the key enzyme in polymyxin resistance.
J.Struct.Biol., 175, 2011
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3PLR
 | | Crystal structure of Klebsiella pneumoniae UDP-glucose 6-dehydrogenase complexed with NADH and UDP-glucose | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, UDP-glucose 6-dehydrogenase, URIDINE-5'-MONOPHOSPHATE | | 著者 | Chen, Y.-Y, Ko, T.-P, Lin, C.-H, Chen, W.-H, Wang, A.H.-J. | | 登録日 | 2010-11-15 | | 公開日 | 2011-09-28 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Conformational change upon product binding to Klebsiella pneumoniae UDP-glucose dehydrogenase: a possible inhibition mechanism for the key enzyme in polymyxin resistance.
J.Struct.Biol., 175, 2011
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3PLN
 | | Crystal structure of Klebsiella pneumoniae UDP-glucose 6-dehydrogenase complexed with UDP-glucose | | 分子名称: | UDP-glucose 6-dehydrogenase, URIDINE-5'-MONOPHOSPHATE | | 著者 | Chen, Y.-Y, Ko, T.-P, Lin, C.-H, Chen, W.-H, Wang, A.H.-J. | | 登録日 | 2010-11-15 | | 公開日 | 2011-09-28 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Conformational change upon product binding to Klebsiella pneumoniae UDP-glucose dehydrogenase: a possible inhibition mechanism for the key enzyme in polymyxin resistance.
J.Struct.Biol., 175, 2011
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