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3O5X
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BU of 3o5x by Molmil
Crystal structure of the oncogenic tyrosine phosphatase SHP2 complexed with a salicylic acid-based small molecule inhibitor
分子名称: 3-{1-[3-(biphenyl-4-ylamino)-3-oxopropyl]-1H-1,2,3-triazol-4-yl}-6-hydroxy-1-methyl-2-phenyl-1H-indole-5-carboxylic acid, Tyrosine-protein phosphatase non-receptor type 11
著者Zhang, Z.-Y, Zhang, X, He, Y, Liu, S, Yu, Z, Jiang, Z, Yang, Z, Dong, Y, Nabinger, S.C, Wu, L, Gunawan, A.M, Wang, L, Chan, R.J.
登録日2010-07-28
公開日2010-08-11
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Salicylic acid based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2).
J.Med.Chem., 53, 2010
1HNA
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BU of 1hna by Molmil
CRYSTAL STRUCTURE OF HUMAN CLASS MU GLUTATHIONE TRANSFERASE GSTM2-2: EFFECTS OF LATTICE PACKING ON CONFORMATIONAL HETEROGENEITY
分子名称: GLUTATHIONE S-(2,4 DINITROBENZENE), GLUTATHIONE S-TRANSFERASE
著者Raghunathan, S, Chandross, R.J, Kretsinger, R.H, Allison, T.J, Penington, C.J, Rule, G.S.
登録日1993-10-15
公開日1994-01-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of human class mu glutathione transferase GSTM2-2. Effects of lattice packing on conformational heterogeneity.
J.Mol.Biol., 238, 1994
1HNB
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BU of 1hnb by Molmil
CRYSTAL STRUCTURE OF HUMAN CLASS MU GLUTATHIONE TRANSFERASE GSTM2-2: EFFECTS OF LATTICE PACKING ON CONFORMATIONAL HETEROGENEITY
分子名称: GLUTATHIONE S-(2,4 DINITROBENZENE), GLUTATHIONE S-TRANSFERASE
著者Raghunathan, S, Chandross, R.J, Kretsinger, R.H, Allison, T.J, Penington, C.J, Rule, G.S.
登録日1993-10-15
公開日1994-01-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Crystal structure of human class mu glutathione transferase GSTM2-2. Effects of lattice packing on conformational heterogeneity.
J.Mol.Biol., 238, 1994
1HNC
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CRYSTAL STRUCTURE OF HUMAN CLASS MU GLUTATHIONE TRANSFERASE GSTM2-2: EFFECTS OF LATTICE PACKING ON CONFORMATIONAL HETEROGENEITY
分子名称: GLUTATHIONE S-(2,4 DINITROBENZENE), GLUTATHIONE S-TRANSFERASE
著者Raghunathan, S, Chandross, R.J, Kretsinger, R.H, Allison, T.J, Penington, C.J, Rule, G.S.
登録日1993-10-15
公開日1994-01-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of human class mu glutathione transferase GSTM2-2. Effects of lattice packing on conformational heterogeneity.
J.Mol.Biol., 238, 1994
3MOW
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BU of 3mow by Molmil
Crystal structure of SHP2 in complex with a tautomycetin analog TTN D-1
分子名称: (2Z)-2-[(1R)-3-{[(1R,2S,3R,6S,7S,10S,12S,15E,17E)-18-carboxy-16-ethyl-3,7-dihydroxy-1,2,6,10,12-pentamethyl-5-oxooctade ca-15,17-dien-1-yl]oxy}-1-hydroxy-3-oxopropyl]-3-methylbut-2-enedioic acid, Tyrosine-protein phosphatase non-receptor type 11
著者Zhang, Z.-Y, Liu, S, Yu, Z, Yu, X.
登録日2010-04-23
公開日2011-05-04
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of SHP2 in complex with a tautomycetin analog TTN D-1
To be Published
1AHR
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BU of 1ahr by Molmil
CALMODULIN MUTANT WITH A TWO RESIDUE DELETION IN THE CENTRAL HELIX
分子名称: CALCIUM ION, CALMODULIN
著者Tabernero, L, Sack, J.
登録日1997-04-10
公開日1997-06-16
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structure of a calmodulin mutant with a deletion in the central helix: implications for molecular recognition and protein binding.
Structure, 5, 1997
3GTU
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LIGAND-FREE HETERODIMERIC HUMAN GLUTATHIONE S-TRANSFERASE M2-3 (EC 2.5.1.18), MONOCLINIC CRYSTAL FORM
分子名称: GLUTATHIONE S-TRANSFERASE
著者Patskovsky, Y.V, Patskovska, L.N, Listowsky, I.
登録日1998-07-29
公開日1999-07-29
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献An asparagine-phenylalanine substitution accounts for catalytic differences between hGSTM3-3 and other human class mu glutathione S-transferases.
Biochemistry, 38, 1999
1DEG
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BU of 1deg by Molmil
THE LINKER OF DES-GLU84 CALMODULIN IS BENT AS SEEN IN THE CRYSTAL STRUCTURE
分子名称: CALCIUM ION, CALMODULIN
著者Raghunathan, S, Chandross, R, Cheng, B.P, Persechini, A, Sobottk, S.E, Kretsinger, R.H.
登録日1993-06-07
公開日1994-05-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The linker of des-Glu84-calmodulin is bent.
Proc.Natl.Acad.Sci.Usa, 90, 1993
2AB6
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HUMAN GLUTATHIONE S-TRANSFERASE M2-2 (E.C.2.5.1.18) complexed with S-METHYLGLUTATHIONE
分子名称: Glutathione S-transferase Mu 2, L-GAMMA-GLUTAMYL-S-METHYLCYSTEINYLGLYCINE
著者Patskovsky, Y, Almo, S.C, Listowsky, I.
登録日2005-07-14
公開日2005-08-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Perturbations in the Active Site of Human Glutathione-S-Transferase M2-2 Upon Ligand Binding
To be Published
1YKC
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BU of 1ykc by Molmil
human glutathione S-transferase m2-2 (E.C.2.5.1.18) complexed with glutathione-disulfide
分子名称: Glutathione S-transferase Mu 2, OXIDIZED GLUTATHIONE DISULFIDE
著者Patskovsky, Y.V, Patskovska, L.N, Listowsky, I, Almo, S.C.
登録日2005-01-17
公開日2005-01-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Selective Inhibitors of Prostaglandin Synthase activity of human glutathione S-transferase M2-2
To be Published
1XW5
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Human glutathione s-transferase M2-2 (E.C.2.5.1.18)complexed with glutathione, monoclinic crystal form
分子名称: GLUTATHIONE, Glutathione S-transferase Mu 2
著者Patskovska, L.N, Patskovsky, Y.V, Almo, S.C, Listowsky, I.
登録日2004-10-29
公開日2004-11-30
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Perturbation of the Active Site of Human Glutathione-S-Transferase M2-2 Upon Ligand Binding
To be Published
2GTU
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LIGAND-FREE HUMAN GLUTATHIONE S-TRANSFERASE M2-2 (E.C.2.5.1.18), MONOCLINIC CRYSTAL FORM
分子名称: GLUTATHIONE S-TRANSFERASE
著者Patskovska, L.N, Fedorov, A.A, Patskovsky, Y.V, Almo, S.C, Listowsky, I.
登録日1998-05-26
公開日1999-03-02
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献The enhanced affinity for thiolate anion and activation of enzyme-bound glutathione is governed by an arginine residue of human Mu class glutathione S-transferases.
J.Biol.Chem., 275, 2000
1GSU
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AN AVIAN CLASS-MU GLUTATHIONE S-TRANSFERASE, CGSTM1-1 AT 1.94 ANGSTROM RESOLUTION
分子名称: CLASS-MU GLUTATHIONE S-TRANSFERASE, S-HEXYLGLUTATHIONE
著者Sun, Y.-J, Kuan, C, Tam, M.F, Hsiao, C.-D.
登録日1997-09-02
公開日1998-03-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献The three-dimensional structure of an avian class-mu glutathione S-transferase, cGSTM1-1 at 1.94 A resolution.
J.Mol.Biol., 278, 1998

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件を2024-07-31に公開中

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