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6PNL
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BU of 6pnl by Molmil
Structure of Epimerase Mth375 from the thermophilic pseudomurein-containing methanogen Methanothermobacter thermautotrophicus
分子名称: 1,2-ETHANEDIOL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ...
著者Carbone, V, Schofield, L.R, Sutherland-Smith, A.J, Ronimus, R.S.
登録日2019-07-02
公開日2020-07-08
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Structure of a UDP-GALE 4-epimerase (Mth375) from the thermophilic pseudomurein-containing methanogen Methanothermobacter thermautotrophicus
To Be Published
6PLJ
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BU of 6plj by Molmil
A nucleotidyl transferase from Methanothermobacter thermautotroptrophicus (Mth528)
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, SODIUM ION, ...
著者Carbone, V, Schofield, L, Sutherland-Smith, A, Ronimus, R.
登録日2019-07-01
公開日2020-07-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献A nucleotidyl transferase from Methanothermobacter thermautotroptrophicus (Mth528)
To Be Published
6PMH
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BU of 6pmh by Molmil
Structure of Epimerase Mth375 from the thermophilic pseudomurein-containing methanogen Methanothermobacter thermautotrophicus
分子名称: ADENOSINE MONOPHOSPHATE, CHLORIDE ION, GLYCEROL, ...
著者Carbone, V, Schofield, L.R, Sutherland-Smith, A.J, Ronimus, R.S.
登録日2019-07-01
公開日2020-07-08
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of a UDP-GALE 4-epimerase (Mth375) from the thermophilic pseudomurein-containing methanogen Methanothermobacter thermautotrophicus
To Be Published
4RGQ
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BU of 4rgq by Molmil
Crystal structure of the Methanocaldococcus jannaschii G1PDH with NADPH and DHAP
分子名称: 1,2-ETHANEDIOL, 1,3-DIHYDROXYACETONEPHOSPHATE, Glycerol-1-phosphate dehydrogenase, ...
著者Carbone, V, Ronimus, R.S, Schofield, L.R, Sutherland-Smith, A.J.
登録日2014-09-30
公開日2015-07-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Structure and Evolution of the Archaeal Lipid Synthesis Enzyme sn-Glycerol-1-phosphate Dehydrogenase.
J.Biol.Chem., 290, 2015
4RGV
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BU of 4rgv by Molmil
Crystal structure of the Methanocaldococcus jannaschii G1PDH
分子名称: Glycerol-1-phosphate dehydrogenase, MAGNESIUM ION, ZINC ION
著者Carbone, V, Ronimus, R.S, Schofield, L.R, Sutherland-Smith, A.J.
登録日2014-09-30
公開日2015-07-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structure and Evolution of the Archaeal Lipid Synthesis Enzyme sn-Glycerol-1-phosphate Dehydrogenase.
J.Biol.Chem., 290, 2015
4RFL
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BU of 4rfl by Molmil
Crystal structure of G1PDH with NADPH from Methanocaldococcus jannaschii
分子名称: 1,2-ETHANEDIOL, Glycerol-1-phosphate dehydrogenase [NAD(P)+], NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Carbone, V, Ronimus, R.S, Schofield, L.R, Sutherland-Smith, A.J.
登録日2014-09-26
公開日2015-07-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure and Evolution of the Archaeal Lipid Synthesis Enzyme sn-Glycerol-1-phosphate Dehydrogenase.
J.Biol.Chem., 290, 2015
6P8C
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BU of 6p8c by Molmil
2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase (MthRED) from Methanothermobacter thermautotrophicus
分子名称: 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase, CHLORIDE ION, GLYCEROL, ...
著者Carbone, V, Schofield, L.R, Hannus, I, Sutherland-Smith, A.J, Ronimus, R.S.
登録日2019-06-06
公開日2020-06-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献The Crystal Structure of 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase (MthRED) from Methanothermobacter thermautotrophicus
To Be Published
6DNT
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BU of 6dnt by Molmil
UDP-N-acetylglucosamine 4-epimerase from Methanobrevibacter ruminantium M1 in complex with UDP-N-acetylmuramic acid
分子名称: (2R)-2-{[(2R,3R,4R,5S,6R)-3-(acetylamino)-2-{[(S)-{[(R)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoic acid, 1,2-ETHANEDIOL, NAD-dependent epimerase/dehydratase, ...
著者Carbone, V, Schofield, L.R, Sang, C, Sutherland-Smith, A.J, Ronimus, R.S.
登録日2018-06-07
公開日2018-10-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Structural determination of archaeal UDP-N-acetylglucosamine 4-epimerase from Methanobrevibacter ruminantium M1 in complex with the bacterial cell wall intermediate UDP-N-acetylmuramic acid.
Proteins, 86, 2018
8TMS
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BU of 8tms by Molmil
Crystal structure of bacterial pectin methylesterase PmeC2 from rumen Butyrivibrio
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Pectinesterase
著者Carbone, V, Reilly, K, Sang, C, Schofield, L, Ronimus, R, Kelly, W.J, Attwood, G.T, Palevich, N.
登録日2023-07-30
公開日2023-08-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structures of Bacterial Pectin Methylesterases Pme8A and PmeC2 from Rumen Butyrivibrio .
Int J Mol Sci, 24, 2023
8TNE
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BU of 8tne by Molmil
Crystal structure of bacterial pectin methylesterase Pme8A from rumen Butyrivibrio
分子名称: 1,2-ETHANEDIOL, Pectinesterase
著者Carbone, V, Reilly, K, Sang, C, Schofield, L, Ronimus, R, Kelly, W.J, Attwood, G.T, Palevich, N.
登録日2023-08-01
公開日2023-08-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structures of Bacterial Pectin Methylesterases Pme8A and PmeC2 from Rumen Butyrivibrio .
Int J Mol Sci, 24, 2023
4FIO
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BU of 4fio by Molmil
Crystal Structure of Methenyltetrahydromethanopterin Cyclohydrolase from Methanobrevibacter ruminantium
分子名称: ETHYL ACETATE, ISOPROPYL ALCOHOL, Methenyltetrahydromethanopterin cyclohydrolase
著者Carbone, V, Schofield, L.R, Beattie, A.K, Sutherland-Smith, A.J, Ronimus, R.S.
登録日2012-06-10
公開日2013-07-24
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献The crystal structure of methenyltetrahydromethanopterin cyclohydrolase from Methanobrevibacter ruminantium.
Proteins, 81, 2013
2O4U
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BU of 2o4u by Molmil
Crystal structure of Mammalian Dimeric Dihydrodiol Dehydrogenase
分子名称: BETA-MERCAPTOETHANOL, Dimeric dihydrodiol dehydrogenase, GLYCEROL, ...
著者Carbone, V, El-Kabbani, O.
登録日2006-12-04
公開日2007-07-31
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of dimeric dihydrodiol dehydrogenase apoenzyme and inhibitor complex: probing the subunit interface with site-directed mutagenesis.
Proteins, 70, 2008
3FX4
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BU of 3fx4 by Molmil
Porcine aldehyde reductase in ternary complex with inhibitor
分子名称: Alcohol dehydrogenase [NADP+], NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION, ...
著者Carbone, V, El-Kabbani, O.
登録日2009-01-20
公開日2009-12-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structure of aldehyde reductase in ternary complex with a 5-arylidene-2,4-thiazolidinedione aldose reductase inhibitor.
Eur.J.Med.Chem., 45, 2010
3CV7
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BU of 3cv7 by Molmil
Crystal structure of porcine aldehyde reductase ternary complex
分子名称: 3,5-dichloro-2-hydroxybenzoic acid, Alcohol dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Carbone, V, El-Kabbani, O.
登録日2008-04-18
公開日2008-10-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.412 Å)
主引用文献Structure of aldehyde reductase in ternary complex with coenzyme and the potent 20alpha-hydroxysteroid dehydrogenase inhibitor 3,5-dichlorosalicylic acid: Implications for inhibitor binding and selectivity
Arch.Biochem.Biophys., 479, 2008
2POQ
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BU of 2poq by Molmil
Dimeric Dihydrodiol Dehydrogenase complexed with inhibitor, Isoascorbic acid
分子名称: BETA-MERCAPTOETHANOL, Dimeric dihydrodiol dehydrogenase, ISOASCORBIC ACID, ...
著者Carbone, V, El-Kabbani, O.
登録日2007-04-27
公開日2007-07-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Structure of monkey dimeric dihydrodiol dehydrogenase in complex with isoascorbic acid.
Acta Crystallogr.,Sect.D, 64, 2008
2O48
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BU of 2o48 by Molmil
Crystal structure of Mammalian Dimeric Dihydrodiol Dehydrogenase
分子名称: BETA-MERCAPTOETHANOL, Dimeric dihydrodiol dehydrogenase, P-HYDROXYACETOPHENONE, ...
著者Carbone, V, El-Kabbani, O.
登録日2006-12-04
公開日2007-07-31
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Structures of dimeric dihydrodiol dehydrogenase apoenzyme and inhibitor complex: probing the subunit interface with site-directed mutagenesis.
Proteins, 70, 2008
6VR7
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BU of 6vr7 by Molmil
Structure of a pseudomurein peptide ligase type C from Methanothermus fervidus
分子名称: ACETOACETIC ACID, GLYCEROL, Mur ligase middle domain protein, ...
著者Carbone, V, Schofield, L.R, Sutherland-Smith, A.J, Ronimus, R.S, Subedi, B.P.
登録日2020-02-06
公開日2021-02-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Archaeal pseudomurein and bacterial murein cell wall biosynthesis share a common evolutionary ancestry
FEMS Microbes, 2, 2021
6VR8
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BU of 6vr8 by Molmil
Structure of a pseudomurein peptide ligase type E from Methanothermus fervidus
分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, Mur ligase middle domain protein, ...
著者Carbone, V, Schofield, L.R, Sutherland-Smith, A.J, Ronimus, R.S, Subedi, B.P.
登録日2020-02-06
公開日2021-08-11
最終更新日2023-02-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural characterisation of methanogen pseudomurein cell wall peptide ligases homologous to bacterial MurE/F murein peptide ligases.
Microbiology (Reading, Engl.), 168, 2022
7UFP
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BU of 7ufp by Molmil
Structure of a pseudomurein peptide ligase type E from Methanothermus fervidus
分子名称: Mur ligase middle domain protein, SULFATE ION, URIDINE-5'-DIPHOSPHATE
著者Carbone, V, Schofield, L.R, Sutherland-Smith, A.J, Ronimus, R.S, Subedi, B.P.
登録日2022-03-23
公開日2022-10-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural characterisation of methanogen pseudomurein cell wall peptide ligases homologous to bacterial MurE/F murein peptide ligases.
Microbiology (Reading, Engl.), 168, 2022
7TZI
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BU of 7tzi by Molmil
Structure of a pseudomurein peptide ligase type E from Methanothermobacter thermautotrophicus
分子名称: Mur ligase family protein
著者Carbone, V, Schofield, L.R, Sutherland-Smith, A.J, Ronimus, R.S, Subedi, B.P.
登録日2022-02-15
公開日2022-10-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.911 Å)
主引用文献Structural characterisation of methanogen pseudomurein cell wall peptide ligases homologous to bacterial MurE/F murein peptide ligases.
Microbiology (Reading, Engl.), 168, 2022
3H4G
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BU of 3h4g by Molmil
Structure of aldehyde reductase holoenzyme in complex with potent aldose reductase inhibitor Fidarestat: Implications for inhibitor binding and selectivity
分子名称: (2S,4S)-2-AMINOFORMYL-6-FLUORO-SPIRO[CHROMAN-4,4'-IMIDAZOLIDINE]-2',5'-DIONE, Alcohol dehydrogenase [NADP+], NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Carbone, V, El-Kabbani, O.
登録日2009-04-20
公開日2009-05-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of aldehyde reductase holoenzyme in complex with the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity
J.Med.Chem., 48, 2005
7JT8
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BU of 7jt8 by Molmil
Apo structure of a pseudomurein peptide ligase type E from Methanothermus fervidus
分子名称: MAGNESIUM ION, Mur ligase middle domain protein, SULFATE ION
著者Carbone, V, Schofield, L.R, Sutherland-Smith, A.J, Ronimus, R.S, Subedi, B.P.
登録日2020-08-17
公開日2021-09-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Structural characterisation of methanogen pseudomurein cell wall peptide ligases homologous to bacterial MurE/F murein peptide ligases.
Microbiology (Reading, Engl.), 168, 2022
8W33
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BU of 8w33 by Molmil
Structure of McrD (methyl-coenzyme M reductase operon protein D) from Methanomassiliicoccus luminyensis
分子名称: GLYCEROL, McrD (methyl-coenzyme M reductase operon protein D)
著者Sutherland-Smith, A.J, Carbone, V, Schofield, L.R, Ronimus, R.S.
登録日2024-02-21
公開日2024-07-03
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The crystal structure of methanogen McrD, a methyl-coenzyme M reductase-associated protein.
Febs Open Bio, 2024
1WNT
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BU of 1wnt by Molmil
Structure of the tetrameric form of Human L-Xylulose Reductase
分子名称: L-xylulose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者El-Kabbani, O, Carbone, V, Darmanin, C, Ishikura, S, Hara, A.
登録日2004-08-09
公開日2005-07-19
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the tetrameric form of human L-Xylulose reductase: Probing the inhibitor-binding site with molecular modeling and site-directed mutagenesis
Proteins, 60, 2005
1PR9
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BU of 1pr9 by Molmil
Human L-Xylulose Reductase Holoenzyme
分子名称: DIHYDROGENPHOSPHATE ION, L-XYLULOSE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者El-Kabbani, O, Ishikura, S, Darmanin, C, Carbone, V, Chung, R.P.-T, Usami, N, Hara, A.
登録日2003-06-20
公開日2004-02-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Crystal structure of human L-xylulose reductase holoenzyme: probing the role of Asn107 with site-directed mutagenesis
Proteins, 55, 2004

 

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