7TZJ
 
 | | SARS CoV-2 PLpro in complex with inhibitor 3k | | 分子名称: | DIMETHYL SULFOXIDE, N-[(3-fluorophenyl)methyl]-1-[(1R)-1-naphthalen-1-ylethyl]piperidine-4-carboxamide, Papain-like protease, ... | | 著者 | Calleja, D.J, Klemm, T, Lechtenberg, B.C, Kuchel, N.W, Lessene, G, Komander, D. | | 登録日 | 2022-02-15 | | 公開日 | 2022-03-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | | 主引用文献 | Insights Into Drug Repurposing, as Well as Specificity and Compound Properties of Piperidine-Based SARS-CoV-2 PLpro Inhibitors.
Front Chem, 10, 2022
|
|
6XA9
 | | SARS CoV-2 PLpro in complex with ISG15 C-terminal domain propargylamide | | 分子名称: | GLYCEROL, ISG15 CTD-propargylamide, Non-structural protein 3, ... | | 著者 | Klemm, T, Calleja, D.J, Richardson, L.W, Lechtenberg, B.C, Komander, D. | | 登録日 | 2020-06-04 | | 公開日 | 2020-06-17 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2.
Embo J., 39, 2020
|
|
6XAA
 | | SARS CoV-2 PLpro in complex with ubiquitin propargylamide | | 分子名称: | Non-structural protein 3, Ubiquitin-propargylamide, ZINC ION | | 著者 | Klemm, T, Calleja, D.J, Richardson, L.W, Lechtenberg, B.C, Komander, D. | | 登録日 | 2020-06-04 | | 公開日 | 2020-06-17 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2.
Embo J., 39, 2020
|
|
8VEC
 | | Deep Mutational Scanning of SARS-CoV-2 PLpro | | 分子名称: | Papain-like protease nsp3, ZINC ION | | 著者 | Wu, X, Nguyen, J.V, Call, M.E, Call, M.J. | | 登録日 | 2023-12-18 | | 公開日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Mutational Profiling of SARS-CoV-2 PLpro in human cells reveals requirements for function, structure, and drug escape
Biorxiv, 2024
|
|
7M6T
 | | Crystal structure of SOCS2/ElonginB/ElonginC bound to a non-canonical peptide that enhances phospho-peptide binding | | 分子名称: | Elongin-B, Elongin-C, Non-canonical peptide F3, ... | | 著者 | Kershaw, N.J, Li, K, Linossi, E.M, Nicholson, S.E. | | 登録日 | 2021-03-26 | | 公開日 | 2021-10-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.194 Å) | | 主引用文献 | Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands.
Nat Commun, 12, 2021
|
|
