1KCQ
 
 | | Human Gelsolin Domain 2 with a Cd2+ bound | | 分子名称: | CADMIUM ION, GELSOLIN | | 著者 | Kazmirski, S.L, Isaacson, R.L, An, C, Buckle, A, Johnson, C.M, Daggett, V, Fersht, A.R. | | 登録日 | 2001-11-09 | | 公開日 | 2002-01-04 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Loss of a metal-binding site in gelsolin leads to familial amyloidosis-Finnish type.
Nat.Struct.Biol., 9, 2002
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1BRK
 | | BARNASE MUTANT WITH ILE 96 REPLACED BY ALA | | 分子名称: | BARNASE, ZINC ION | | 著者 | Cramer, P.C, Buckle, A, Fersht, A. | | 登録日 | 1995-03-09 | | 公開日 | 1995-07-10 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities.
Biochemistry, 35, 1996
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1BRJ
 | | BARNASE MUTANT WITH ILE 88 REPLACED BY ALA | | 分子名称: | BARNASE, ZINC ION | | 著者 | Cramer, P.C, Buckle, A, Fersht, A. | | 登録日 | 1995-03-09 | | 公開日 | 1995-07-10 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities.
Biochemistry, 35, 1996
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1BRH
 | | BARNASE MUTANT WITH LEU 14 REPLACED BY ALA | | 分子名称: | BARNASE, ZINC ION | | 著者 | Cramer, P.C, Buckle, A, Fersht, A. | | 登録日 | 1995-03-09 | | 公開日 | 1995-07-10 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities.
Biochemistry, 35, 1996
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1BRI
 | | BARNASE MUTANT WITH ILE 76 REPLACED BY ALA | | 分子名称: | BARNASE | | 著者 | Cramer, P.C, Buckle, A, Fersht, A. | | 登録日 | 1995-03-09 | | 公開日 | 1995-07-10 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities.
Biochemistry, 35, 1996
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5CZV
 | | Crystal structure of Notch3 NRR in complex with 20350 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fab 20350 heavy chain, ... | | 著者 | Hu, T, Fryer, C, Chopra, R, Clark, K. | | 登録日 | 2015-08-01 | | 公開日 | 2016-06-01 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | | 主引用文献 | Characterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies.
Oncogene, 35, 2016
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8UDZ
 | | The Structure of LTBP-49247 Fab Bound to TGFbeta1 Small Latent Complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, LTBP-49247 Fab Heavy Chain, LTBP-49247 Fab Light Chain, ... | | 著者 | Streich Jr, F.C, Nicholls, S.B, Boston, C.J, Ramachandran, S. | | 登録日 | 2023-09-29 | | 公開日 | 2024-07-17 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | An antibody that inhibits TGF-beta 1 release from latent extracellular matrix complexes attenuates the progression of renal fibrosis.
Sci.Signal., 17, 2024
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5CZX
 | | Crystal structure of Notch3 NRR in complex with 20358 Fab | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 20358 Fab heavy chain, ... | | 著者 | Hu, T, Fryer, C, Chopra, R, Clark, K. | | 登録日 | 2015-08-01 | | 公開日 | 2016-06-01 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Characterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies.
Oncogene, 35, 2016
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