5K6K
 
 | | Zika virus non-structural protein 1 (NS1) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, SULFATE ION, ... | | 著者 | Akey, D.L, Brown, W.C, Smith, J.L. | | 登録日 | 2016-05-24 | | 公開日 | 2016-07-06 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Extended surface for membrane association in Zika virus NS1 structure.
Nat.Struct.Mol.Biol., 23, 2016
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5W3V
 | | Crystal Structure of macaque APOBEC3H in complex with RNA | | 分子名称: | Apobec3H, RNA (5'-R(P*AP*AP*CP*CP*CP*CP*GP*GP*GP*C)-3'), RNA (5'-R(P*AP*AP*CP*CP*CP*GP*GP*GP*GP*A)-3'), ... | | 著者 | Bohn, J.A, Thummar, K, York, A, Raymond, A, Brown, W.C, Bieniasz, P.D, Hatziioannou, T, Smith, J.L. | | 登録日 | 2017-06-08 | | 公開日 | 2017-10-25 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.243 Å) | | 主引用文献 | APOBEC3H structure reveals an unusual mechanism of interaction with duplex RNA.
Nat Commun, 8, 2017
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4TPL
 | | West Nile Virus Non-structural protein 1 (NS1) Form 1 crystal | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, OXTOXYNOL-10, ... | | 著者 | Akey, D.L, Smith, J.L. | | 登録日 | 2014-06-08 | | 公開日 | 2014-10-15 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Use of massively multiple merged data for low-resolution S-SAD phasing and refinement of flavivirus NS1.
Acta Crystallogr.,Sect.D, 70, 2014
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6WER
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6WEQ
 | | DENV1 NS1 in complex with neutralizing 2B7 Fab fragment | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2B7 Fab fragment heavy chain, 2B7 Fab fragment light chain, ... | | 著者 | Akey, D.L, Smith, J.L. | | 登録日 | 2020-04-02 | | 公開日 | 2020-12-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for antibody inhibition of flavivirus NS1-triggered endothelial dysfunction.
Science, 371, 2021
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6NKH
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6NKK
 | | Structure of PhqE Reductase/Diels-Alderase from Penicillium fellutanum in complex with NADP+ and premalbrancheamide | | 分子名称: | (5aS,12aS,13aS)-12,12-dimethyl-2,3,11,12,12a,13-hexahydro-1H,5H,6H-5a,13a-(epiminomethano)indolizino[7,6-b]carbazol-14-one, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short chain dehydrogenase | | 著者 | Newmister, S.A, Dan, Q, Smith, J.L, Sherman, D.H. | | 登録日 | 2019-01-07 | | 公開日 | 2019-10-09 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.299 Å) | | 主引用文献 | Fungal indole alkaloid biogenesis through evolution of a bifunctional reductase/Diels-Alderase.
Nat.Chem., 11, 2019
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6NKI
 | | Structure of PhqB Reductase Domain from Penicillium fellutanum | | 分子名称: | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NRPS | | 著者 | Dan, Q, Newmister, S.A, Smith, J.L, Sherman, D.H. | | 登録日 | 2019-01-07 | | 公開日 | 2019-10-09 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Fungal indole alkaloid biogenesis through evolution of a bifunctional reductase/Diels-Alderase.
Nat.Chem., 11, 2019
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6NKM
 | | Structure of PhqE D166N Reductase/Diels-Alderase from Penicillium fellutanum in complex with NADP+ and substrate | | 分子名称: | 3-{[2-(2-methylbut-3-en-2-yl)-1H-indol-3-yl]methyl}-8H-pyrrolo[1,2-a]pyrazin-5-ium-1-olate, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short chain dehydrogenase | | 著者 | Newmister, S.A, Dan, Q, Smith, J.L, Sherman, D.H. | | 登録日 | 2019-01-07 | | 公開日 | 2019-10-09 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.896 Å) | | 主引用文献 | Fungal indole alkaloid biogenesis through evolution of a bifunctional reductase/Diels-Alderase.
Nat.Chem., 11, 2019
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6D7A
 | | Structure of T. gondii PLP1 beta-rich domain | | 分子名称: | Perforin-like protein 1, SODIUM ION | | 著者 | Guerra, A.J, Koropatkin, N.M, Wawrzak, Z, Bahr, C.M.E, Carruthers, V.B. | | 登録日 | 2018-04-24 | | 公開日 | 2018-05-16 | | 最終更新日 | 2019-12-18 | | 実験手法 | X-RAY DIFFRACTION (1.13 Å) | | 主引用文献 | Structural basis of Toxoplasma gondii perforin-like protein 1 membrane interaction and activity during egress.
PLoS Pathog., 14, 2018
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4WXY
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4WY0
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4WXZ
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6MCE
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6MCF
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6MCI
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3U1T
 | | Haloalkane Dehalogenase, DmmA, of marine microbial origin | | 分子名称: | CHLORIDE ION, DmmA Haloalkane Dehalogenase, MALONATE ION | | 著者 | Gehret, J.J, Smith, J.L. | | 登録日 | 2011-09-30 | | 公開日 | 2011-12-28 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure and activity of DmmA, a marine haloalkane dehalogenase.
Protein Sci., 21, 2012
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4O6D
 | | West Nile Virus Non-structural protein 1 (NS1) Form 1 crystal | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, NS1, ... | | 著者 | Akey, D.L, Smith, J.L. | | 登録日 | 2013-12-20 | | 公開日 | 2014-02-19 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.5936 Å) | | 主引用文献 | Flavivirus NS1 structures reveal surfaces for associations with membranes and the immune system.
Science, 343, 2014
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4O6B
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4MZ0
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4MYY
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4MYZ
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4O6C
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7K93
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5TCC
 | | Complement Factor D inhibited with JH4 | | 分子名称: | (2S)-N-(6-bromopyridin-2-yl)-3-[(1H-indazol-1-yl)acetyl]-1,3-thiazolidine-2-carboxamide, Complement factor D | | 著者 | Stuckey, J.A. | | 登録日 | 2016-09-14 | | 公開日 | 2016-10-19 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.37 Å) | | 主引用文献 | Buried Hydrogen Bond Interactions Contribute to the High Potency of Complement Factor D Inhibitors.
ACS Med Chem Lett, 7, 2016
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