5ONO
 
 | | Crystal Structure of Ectoine Synthase from P. lautus | | 分子名称: | (4S)-2-METHYL-1,4,5,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, FE (III) ION, L-ectoine synthase | | 著者 | Bremer, E. | | 登録日 | 2017-08-04 | | 公開日 | 2018-08-22 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Illuminating the catalytic core of ectoine synthase through structural and biochemical analysis.
Sci Rep, 9, 2019
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5ONM
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5ONN
 | | Crystal Structure of Ectoine Synthase from P. lautus | | 分子名称: | (2~{S})-4-acetamido-2-azanyl-butanoic acid, FE (III) ION, L-ectoine synthase | | 著者 | Bremer, E. | | 登録日 | 2017-08-04 | | 公開日 | 2018-08-22 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Illuminating the catalytic core of ectoine synthase through structural and biochemical analysis.
Sci Rep, 9, 2019
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6EYL
 | | Crystal structure of OpuBC in complex with carnitine | | 分子名称: | CARNITINE, Osmotically activated L-carnitine/choline ABC transporter substrate-binding protein OpuCC | | 著者 | Peherstorfer, S, Teichmann, L, Smits, S.H, Sschmitt, L, Bremer, E. | | 登録日 | 2017-11-13 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Reprogramming the substrate specificity of an ABC import system by a single amino acid substitution in its cognate ligand binding protein
To Be Published
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5BXX
 | | Crystal structure of the ectoine synthase from the cold-adapted marine bacterium Sphingopyxis alaskensis | | 分子名称: | L-ectoine synthase | | 著者 | Widderich, N, Kobus, S, Hoeppner, A, Bremer, E, Smits, S.H.J. | | 登録日 | 2015-06-09 | | 公開日 | 2016-04-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Biochemistry and Crystal Structure of Ectoine Synthase: A Metal-Containing Member of the Cupin Superfamily.
Plos One, 11, 2016
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3R6U
 | | Crystal structure of choline binding protein OpuBC from Bacillus subtilis | | 分子名称: | CHOLINE ION, Choline-binding protein | | 著者 | Pittelkow, M, Tschapek, B, Smits, S.H.J, Schmitt, L, Bremer, E. | | 登録日 | 2011-03-22 | | 公開日 | 2011-06-15 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | | 主引用文献 | The Crystal Structure of the Substrate-Binding Protein OpuBC from Bacillus subtilis in Complex with Choline.
J.Mol.Biol., 411, 2011
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3MAM
 | | A molecular switch changes the low to the high affinity state in the substrate binding protein AfProX | | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Osmoprotection protein (ProX), ... | | 著者 | Tschapek, B, Pittelkow, M, Bremer, E, Schmitt, L, Smits, S.H. | | 登録日 | 2010-03-24 | | 公開日 | 2011-04-06 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Arg149 Is Involved in Switching the Low Affinity, Open State of the Binding Protein AfProX into Its High Affinity, Closed State.
J.Mol.Biol., 411, 2011
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5BY5
 | | High resolution structure of the ectoine synthase from the cold-adapted marine bacterium Sphingopyxis alaskensis | | 分子名称: | L-ectoine synthase, S-1,2-PROPANEDIOL | | 著者 | Widderich, N, Kobus, S, Hoeppner, A, Bremer, E, Smits, S.H.J. | | 登録日 | 2015-06-10 | | 公開日 | 2016-04-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Biochemistry and Crystal Structure of Ectoine Synthase: A Metal-Containing Member of the Cupin Superfamily.
Plos One, 11, 2016
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3HCQ
 | | Structural analysis of the choline binding protein ChoX in a semi-closed and ligand-free conformation | | 分子名称: | Putative choline ABC transporter, periplasmic solute-binding component | | 著者 | Oswald, C, Smits, S.H.J, Hoeing, M, Bremer, E, Schmitt, L. | | 登録日 | 2009-05-06 | | 公開日 | 2009-10-13 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Structural analysis of the choline-binding protein ChoX in a semi-closed and ligand-free conformation.
Biol.Chem., 390, 2009
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3FXB
 | | Crystal structure of the ectoine-binding protein UehA | | 分子名称: | (4S)-2-METHYL-1,4,5,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, TRAP dicarboxylate transporter, DctP subunit | | 著者 | Lecher, J, Pittelkow, M, Bursy, J, Smits, S.H.J, Schmitt, L, Bremer, E. | | 登録日 | 2009-01-20 | | 公開日 | 2009-05-26 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | The crystal structure of UehA in complex with ectoine-A comparison with other TRAP-T binding proteins.
J.Mol.Biol., 389, 2009
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6EYG
 | | Structure of a OpuBC mutant with bound Glycine betaine | | 分子名称: | Osmotically activated L-carnitine/choline ABC transporter substrate-binding protein OpuCC, TRIMETHYL GLYCINE | | 著者 | Peherstorfer, S, Teichmann, L, Smits, S.H, Schmitt, L, Bremer, E. | | 登録日 | 2017-11-13 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | | 主引用文献 | Structure of a OpuBC mutant with bound Glycine betaine
To Be Published
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6EYQ
 | | Crystal structure of a mutated OpuBC in complex with choline | | 分子名称: | CHOLINE ION, Choline-binding protein | | 著者 | Peherstorfer, S, Teichmann, L, Smits, S.H, Schmitt, L, Bremer, E. | | 登録日 | 2017-11-13 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal structure of a mutated OpuBC in complex with choline
To Be Published
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6EYH
 | | Structure of a OpuBC mutant with bound Glycine betaine | | 分子名称: | 3-(dimethyl-lambda~4~-sulfanyl)propanoic acid, Choline binding protein OpuBC | | 著者 | Peherstorfer, S, Teichmann, L, Smits, S.H, Schmitt, L, Bremer, E. | | 登録日 | 2017-11-13 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure of a OpuBC mutant with bound DMSP
To Be Published
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5NXY
 | | Crystal structure of OpuAC from B. subtilis in complex with Arsenobetaine | | 分子名称: | 1,2-ETHANEDIOL, 2-(trimethyl-lambda~5~-arsanyl)ethanol, Osmotically activated L-carnitine/choline ABC transporter substrate-binding protein OpuCC | | 著者 | Hofmann, T, Bremer, E, Schmitt, L, Smits, S. | | 登録日 | 2017-05-11 | | 公開日 | 2018-03-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Arsenobetaine: an ecophysiologically important organoarsenical confers cytoprotection against osmotic stress and growth temperature extremes.
Environ. Microbiol., 20, 2018
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5NXX
 | | Crystal structure of OpuAC from B. subtilis in complex with Arsenobetaine | | 分子名称: | (trimethylarsonio)acetate, Glycine betaine ABC transport system glycine betaine-binding protein OpuAC | | 著者 | Hofmann, T, Bremer, E, Schmitt, L, Smits, S. | | 登録日 | 2017-05-11 | | 公開日 | 2018-03-28 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Arsenobetaine: an ecophysiologically important organoarsenical confers cytoprotection against osmotic stress and growth temperature extremes.
Environ. Microbiol., 20, 2018
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3CHG
 | | The compatible solute-binding protein OpuAC from Bacillus subtilis in complex with DMSA | | 分子名称: | (dimethyl-lambda~4~-sulfanyl)acetic acid, Glycine betaine-binding protein | | 著者 | Smits, S.H.J, Hoing, M, Lecher, J, Jebbar, M, Schmitt, L, Bremer, E. | | 登録日 | 2008-03-09 | | 公開日 | 2008-08-12 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The Compatible-Solute-Binding Protein OpuAC from Bacillus subtilis: Ligand Binding, Site-Directed Mutagenesis, and Crystallographic Studies
J.Bacteriol., 190, 2008
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4MHU
 | | Crystal structure of EctD from S. alaskensis with bound Fe | | 分子名称: | Ectoine hydroxylase, FE (III) ION, N-DODECYL-N,N-DIMETHYLGLYCINATE | | 著者 | Widderich, N, Hoeppner, A, Pittelkow, M, Heider, J, Smits, S.H, Bremer, E. | | 登録日 | 2013-08-30 | | 公開日 | 2014-09-03 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | Crystal structure of the ectoine hydroxylase, a snapshot of the active site.
J.Biol.Chem., 289, 2014
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4MHR
 | | Crystal structure of EctD from S. alaskensis in its apoform | | 分子名称: | Ectoine hydroxylase | | 著者 | Widderich, N, Hoeppner, A, Pittelkow, M, Heider, J, Smits, S.H, Bremer, E. | | 登録日 | 2013-08-30 | | 公開日 | 2014-09-03 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of the ectoine hydroxylase, a snapshot of the active site.
J.Biol.Chem., 289, 2014
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4NMI
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4Q5O
 | | Crystal structure of EctD from S. alaskensis with 2-oxoglutarate and 5-hydroxyectoine | | 分子名称: | (4S,5S)-5-HYDROXY-2-METHYL-1,4,5,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, 2-OXOGLUTARIC ACID, Ectoine hydroxylase, ... | | 著者 | Hoeppner, A, Widderich, N, Bremer, E, Smits, S.H. | | 登録日 | 2014-04-17 | | 公開日 | 2014-09-10 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | Crystal structure of the ectoine hydroxylase, a snapshot of the active site.
J.Biol.Chem., 289, 2014
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2Q88
 | | Crystal structure of EhuB in complex with ectoine | | 分子名称: | (4S)-2-METHYL-1,4,5,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CADMIUM ION, Putative ABC transporter amino acid-binding protein | | 著者 | Hanekop, N, Hoeing, M, Sohn-Bosser, L, Jebbar, M, Schmitt, L, Bremer, E. | | 登録日 | 2007-06-09 | | 公開日 | 2008-01-01 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of the ligand-binding protein EhuB from Sinorhizobium meliloti reveals substrate recognition of the compatible solutes ectoine and hydroxyectoine.
J.Mol.Biol., 374, 2007
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2Q89
 | | Crystal structure of EhuB in complex with hydroxyectoine | | 分子名称: | (4S,5S)-5-HYDROXY-2-METHYL-1,4,5,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CADMIUM ION, Putative ABC transporter amino acid-binding protein | | 著者 | Hanekop, N, Hoeing, M, Sohn-Bosser, L, Jebbar, M, Schmitt, L, Bremer, E. | | 登録日 | 2007-06-09 | | 公開日 | 2008-01-01 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of the ligand-binding protein EhuB from Sinorhizobium meliloti reveals substrate recognition of the compatible solutes ectoine and hydroxyectoine.
J.Mol.Biol., 374, 2007
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2REG
 | | ABC-transporter choline binding protein in complex with choline | | 分子名称: | CHOLINE ION, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN | | 著者 | Oswald, C, Schimtt, L, Smits, S.H.J, Hoeing, M, Sohn-Boeser, L, Bremer, E. | | 登録日 | 2007-09-26 | | 公開日 | 2008-09-16 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structures of the choline/acetylcholine substrate-binding protein ChoX from Sinorhizobium meliloti in the liganded and unliganded-closed states.
J.Biol.Chem., 283, 2008
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2REJ
 | | ABC-transporter choline binding protein in unliganded semi-closed conformation | | 分子名称: | PUTATIVE GLYCINE BETAINE ABC TRANSPORTER PROTEIN | | 著者 | Oswald, C, Smits, S.H.J, Hoeing, M, Sohn-Boeser, L, Le Rudulier, D, Schmitt, L, Bremer, E. | | 登録日 | 2007-09-26 | | 公開日 | 2008-09-16 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structures of the choline/acetylcholine substrate-binding protein ChoX from Sinorhizobium meliloti in the liganded and unliganded-closed states.
J.Biol.Chem., 283, 2008
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2RF1
 | | Crystal structure of ChoX in an unliganded closed conformation | | 分子名称: | PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN | | 著者 | Oswald, C, Smits, S.H.J, Hoeing, M, Sohn-Boeser, L, Le Rudulier, D, Schmitt, L, Bremer, E. | | 登録日 | 2007-09-27 | | 公開日 | 2008-09-16 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structures of the choline/acetylcholine substrate-binding protein ChoX from Sinorhizobium meliloti in the liganded and unliganded-closed states.
J.Biol.Chem., 283, 2008
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