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8PNM
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BU of 8pnm by Molmil
Structure of human KCTD15 BTB domain mutant G88D crystal form 2
分子名称: BTB/POZ domain-containing protein KCTD15
著者Cruz Walma, D.A, Cros, J, Bradshaw, W, Richardson, W, Chen, Z, Chalk, R, Wilkie, A, Bullock, A.N.
登録日2023-06-30
公開日2024-03-20
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献BTB domain mutations perturbing KCTD15 oligomerisation cause a distinctive frontonasal dysplasia syndrome.
J Med Genet, 61, 2024
8PNR
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BU of 8pnr by Molmil
Structure of human KCTD15 BTB domain mutant G88D crystal form 1
分子名称: BTB/POZ domain-containing protein KCTD15
著者Cruz Walma, D.A, Cros, J, Bradshaw, W, Richardson, W, Chen, Z, Chalk, R, Wilkie, A, Bullock, A.N.
登録日2023-06-30
公開日2024-03-20
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献BTB domain mutations perturbing KCTD15 oligomerisation cause a distinctive frontonasal dysplasia syndrome.
J Med Genet, 61, 2024
8OTV
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BU of 8otv by Molmil
Crystal structure of NUDT14 complexed with novel compound
分子名称: 1-(1-methylpiperidin-4-yl)-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-4-amine, DIMETHYL SULFOXIDE, MAGNESIUM ION, ...
著者Balikci, E, Feyerherm, C, Bradshaw, W, Seupel, R, Brennan, P.E, Bountra, C, von Delft, F, Huber, K, Structural Genomics Consortium (SGC)
登録日2023-04-21
公開日2024-05-01
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Unexpected Noncovalent Off-Target Activity of Clinical BTK Inhibitors Leads to Discovery of a Dual NUDT5/14 Antagonist.
J.Med.Chem., 67, 2024

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件を2024-06-26に公開中

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