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Plasmepsin V from Plasmodium vivax bound to a transition state mimetic (WEHI-601)
分子名称:	1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者	Czabotar, P.E, Hodder, A.N, Nguyen, W, Sleebs, B.E, Boddey, J.A, Cowman, A.F.
登録日	2018-01-11
公開日	2018-06-13
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2.39 Å)
主引用文献	Enhanced antimalarial activity of plasmepsin V inhibitors by modification of the P2position of PEXEL peptidomimetics. Eur J Med Chem, 154, 2018

Plasmepsin V from Plasmodium vivax bound to a transition state mimetic (WEHI-842)
分子名称:	(2R)-1-[(2R)-2-(2-methoxyethoxy)propoxy]propan-2-amine, 1,2-ETHANEDIOL, Aspartic protease PM5, ...
著者	Czabotar, P.E, Hodder, A.N, Smith, B.J, Sleebs, B.E, Gazdic, M, Boddey, J.A, Cowman, A.F.
登録日	2015-05-01
公開日	2015-07-15
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (2.37 Å)
主引用文献	Structural basis for plasmepsin V inhibition that blocks export of malaria proteins to human erythrocytes. Nat.Struct.Mol.Biol., 22, 2015

Crystal structure of the Plasmodium vivax Apical membrane antigen (AMA1) in complex with single domain i-body WD34
分子名称:	Apical merozoite antigen 1, single domain i-body WD34
著者	Maddumage, J.C, Kvansakul, M.
登録日	2023-10-17
公開日	2024-07-03
最終更新日	2024-09-04
実験手法	X-RAY DIFFRACTION (3 Å)
主引用文献	A broadly cross-reactive i-body to AMA1 potently inhibits blood and liver stages of Plasmodium parasites. Nat Commun, 15, 2024

Crystal structure of the Plasmodium falciparum Apical membrane antigen (AMA1) in complex with single domain i-body WD34
分子名称:	(4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Apical membrane antigen 1, ...
著者	Maddumage, J.C, Kvansakul, M.
登録日	2023-10-14
公開日	2024-07-03
最終更新日	2024-09-04
実験手法	X-RAY DIFFRACTION (2.6 Å)
主引用文献	A broadly cross-reactive i-body to AMA1 potently inhibits blood and liver stages of Plasmodium parasites. Nat Commun, 15, 2024