5T3E
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5DUA
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5DU9
| First condensation domain of the calcium-dependent antibiotic synthetase in complex with substrate analogue 2a | 分子名称: | (2S)-2-amino-N-butyl-propanamide, CDA peptide synthetase I, CHLORIDE ION, ... | 著者 | Bloudoff, K, Alonzo, D.A, Schmeing, T.M. | 登録日 | 2015-09-18 | 公開日 | 2016-03-30 | 最終更新日 | 2020-01-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Chemical Probes Allow Structural Insight into the Condensation Reaction of Nonribosomal Peptide Synthetases. Cell Chem Biol, 23, 2016
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4JN3
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4JN5
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5JI0
| PPARgamma-RXRalpha(S427F) heterodimer in complex with SRC-1, rosiglitazone, and 9-cis-retanoic acid | 分子名称: | (9cis)-retinoic acid, 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), ... | 著者 | Bloudoff, K, Larsen, N.A. | 登録日 | 2016-04-21 | 公開日 | 2017-04-26 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | PPARgamma-RXRalpha(S427F) heterodimer in complex with SRC-1, rosiglitazone, and 9-cis-retanoic acid To Be Published
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5HZE
| Mek1 adopts DFG-out conformation when bound to an analog of E6201. | 分子名称: | (3S,4R,8S,9S,11E)-8,9,16-trihydroxy-3,4-dimethyl-14-(methylamino)-3,4,5,6,9,10-hexahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione, Dual specificity mitogen-activated protein kinase kinase 1, MAGNESIUM ION | 著者 | Larsen, N.A, Bloudoff, K. | 登録日 | 2016-02-02 | 公開日 | 2017-05-03 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Mek1 adopts DFG-out conformation when bound to an analog of E6201. To Be Published
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7LY6
| Structure of a trans-acting NRPS oxidase, BmdC, involved in bacillamide biosynthesis | 分子名称: | BmdC, NRPS oxidase, FLAVIN MONONUCLEOTIDE, ... | 著者 | Fortinez, C.M, Bloudoff, K, Schmeing, T.M. | 登録日 | 2021-03-05 | 公開日 | 2022-02-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | 主引用文献 | Structures and function of a tailoring oxidase in complex with a nonribosomal peptide synthetase module. Nat Commun, 13, 2022
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6N8G
| IRAK4 bound to benzoxazole compound | 分子名称: | Interleukin-1 receptor-associated kinase 4, N-[2-(morpholin-4-yl)-6-(piperidin-1-yl)-1,3-benzoxazol-5-yl]-6-(1H-pyrrolo[2,3-b]pyridin-5-yl)pyridine-2-carboxamide | 著者 | Larsen, N.A, Bloudoff, K, Subramanian, V, Dobrzanska, M, Gluza, K. | 登録日 | 2018-11-29 | 公開日 | 2018-12-12 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | To be published To Be Published
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7LY5
| Proteolyzed crystal structure of the bacillamide NRPS, BmdB, in complex with the oxidase BmdC | 分子名称: | BmdB, Bacillamide NRPS, BmdC, ... | 著者 | Fortinez, C.M, Schmeing, T.M. | 登録日 | 2021-03-05 | 公開日 | 2022-02-02 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structures and function of a tailoring oxidase in complex with a nonribosomal peptide synthetase module. Nat Commun, 13, 2022
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7LY4
| Cryo-EM structure of the elongation module of the bacillamide NRPS, BmdB, in complex with the oxidase, BmdC | 分子名称: | BmdB, bacillamide NRPS, BmdC, ... | 著者 | Sharon, I, Fortinez, C.M, Schmeing, T.M. | 登録日 | 2021-03-05 | 公開日 | 2022-02-02 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structures and function of a tailoring oxidase in complex with a nonribosomal peptide synthetase module. Nat Commun, 13, 2022
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7LY7
| Crystal structure of the elongation module of the bacillamide NRPS, BmdB, in complex with the oxidase BmdC | 分子名称: | 5'-{[(2R,3S)-3-amino-2-({2-[(N-{(2R)-4-[(dihydroxyphosphanyl)oxy]-2-hydroxy-3,3-dimethylbutanoyl}-beta-alanyl)amino]ethyl}sulfanyl)-4-sulfanylbutane-1-sulfonyl]amino}-5'-deoxyadenosine, BmdB, Bacillamide NRPS, ... | 著者 | Fortinez, C.M, Sharon, I, Schmeing, T.M. | 登録日 | 2021-03-05 | 公開日 | 2022-02-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Structures and function of a tailoring oxidase in complex with a nonribosomal peptide synthetase module. Nat Commun, 13, 2022
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