4DLE
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![BU of 4dle by Molmil](/molmil-images/mine/4dle) | Ternary Structure of the large Fragment of Taq DNA Polymerase: 4-Fluoroproline Variant | 分子名称: | 1,2-ETHANEDIOL, 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA polymerase I, ... | 著者 | Holzberger, B, Obeid, S, Welte, W, Diederichs, K, Marx, A. | 登録日 | 2012-02-06 | 公開日 | 2012-11-28 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | Structural insights into the potential of 4-fluoroproline to modulate biophysical properties of protein Chem Sci, 3, 2012
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4DLG
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![BU of 4dlg by Molmil](/molmil-images/mine/4dlg) | Ternary Structure of the large Fragment of Taq DNA polymerase | 分子名称: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, ACETATE ION, DNA polymerase I, ... | 著者 | Marx, A, Diederichs, K, Obeid, S, Holzberger, B. | 登録日 | 2012-02-06 | 公開日 | 2012-11-28 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Structural insights into the potential of 4-fluoroproline to modulate biophysical properties of protein Chem Sci, 3, 2012
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7JU4
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![BU of 7ju4 by Molmil](/molmil-images/mine/7ju4) | Radial spoke 2 stalk, IDAc, and N-DRC attached with doublet microtubule | 分子名称: | 28 kDa inner dynein arm light chain, axonemal, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Gui, M, Ma, M, Sze-Tu, E, Wang, X, Koh, F, Zhong, E, Berger, B, Davis, J, Dutcher, S, Zhang, R, Brown, A. | 登録日 | 2020-08-19 | 公開日 | 2020-12-16 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structures of radial spokes and associated complexes important for ciliary motility. Nat.Struct.Mol.Biol., 28, 2021
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7JTK
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![BU of 7jtk by Molmil](/molmil-images/mine/7jtk) | Radial spoke 1 isolated from Chlamydomonas reinhardtii | 分子名称: | Cytochrome b5 heme-binding domain-containing protein, Dynein 8 kDa light chain, flagellar outer arm, ... | 著者 | Gui, M, Ma, M, Sze-Tu, E, Wang, X, Koh, F, Zhong, E, Berger, B, Davis, J, Dutcher, S, Zhang, R, Brown, A. | 登録日 | 2020-08-17 | 公開日 | 2020-12-16 | 最終更新日 | 2021-01-27 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structures of radial spokes and associated complexes important for ciliary motility. Nat.Struct.Mol.Biol., 28, 2021
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7JTS
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![BU of 7jts by Molmil](/molmil-images/mine/7jts) | Stalk of radial spoke 1 attached with doublet microtubule from Chlamydomonas reinhardtii | 分子名称: | Calmodulin, Dynein 8 kDa light chain, flagellar outer arm, ... | 著者 | Gui, M, Ma, M, Sze-Tu, E, Wang, X, Koh, F, Zhong, E, Berger, B, Davis, J, Dutcher, S, Zhang, R, Brown, A. | 登録日 | 2020-08-18 | 公開日 | 2020-12-16 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (6.1 Å) | 主引用文献 | Structures of radial spokes and associated complexes important for ciliary motility. Nat.Struct.Mol.Biol., 28, 2021
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5C37
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![BU of 5c37 by Molmil](/molmil-images/mine/5c37) | Structure of the beta-ketoacyl reductase domain of human fatty acid synthase bound to a spiro-imidazolone inhibitor | 分子名称: | 6-{[(3R)-1-(cyclopropylcarbonyl)pyrrolidin-3-yl]methyl}-5-[4-(1-methyl-1H-indazol-5-yl)phenyl]-4,6-diazaspiro[2.4]hept-4-en-7-one, CHLORIDE ION, Fatty acid synthase, ... | 著者 | Schubert, C, Milligan, C.M, Vo, K, Grasberger, B. | 登録日 | 2015-06-17 | 公開日 | 2016-06-22 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Design and synthesis of a series of bioavailable fatty acid synthase (FASN) KR domain inhibitors for cancer therapy. Bioorg.Med.Chem.Lett., 28, 2018
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5MUS
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![BU of 5mus by Molmil](/molmil-images/mine/5mus) | Structure of the C-terminal domain of a reptarenavirus L protein | 分子名称: | CHLORIDE ION, GLYCEROL, L protein | 著者 | Rosenthal, M, Gogrefe, N, Reguera, J, Vogel, D, Rauschenberger, B, Cusack, S, Gunther, S, Reindl, S. | 登録日 | 2017-01-14 | 公開日 | 2017-05-17 | 最終更新日 | 2017-05-24 | 実験手法 | X-RAY DIFFRACTION (2.009 Å) | 主引用文献 | Structural insights into reptarenavirus cap-snatching machinery. PLoS Pathog., 13, 2017
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5MUY
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![BU of 5muy by Molmil](/molmil-images/mine/5muy) | Structure of a C-terminal domain of a reptarenavirus L protein with m7GTP | 分子名称: | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, L protein | 著者 | Rosenthal, M, Gogrefe, N, Reguera, J, Vogel, D, Rauschenberger, B, Cusack, S, Gunther, S, Reindl, S. | 登録日 | 2017-01-14 | 公開日 | 2017-05-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Structural insights into reptarenavirus cap-snatching machinery. PLoS Pathog., 13, 2017
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5MV0
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![BU of 5mv0 by Molmil](/molmil-images/mine/5mv0) | Structure of an N-terminal domain of a reptarenavirus L protein | 分子名称: | L protein, PHOSPHATE ION | 著者 | Rosenthal, M, Gogrefe, N, Reguera, J, Vogel, D, Rauschenberger, B, Cusack, S, Gunther, S, Reindl, S. | 登録日 | 2017-01-14 | 公開日 | 2017-05-17 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Structural insights into reptarenavirus cap-snatching machinery. PLoS Pathog., 13, 2017
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5MUZ
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![BU of 5muz by Molmil](/molmil-images/mine/5muz) | Structure of a C-terminal domain of a reptarenavirus L protein | 分子名称: | L protein | 著者 | Rosenthal, M, Gogrefe, N, Reguera, J, Vogel, D, Rauschenberger, B, Cusack, S, Gunther, S, Reindl, S. | 登録日 | 2017-01-14 | 公開日 | 2017-05-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.776 Å) | 主引用文献 | Structural insights into reptarenavirus cap-snatching machinery. PLoS Pathog., 13, 2017
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6X9H
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![BU of 6x9h by Molmil](/molmil-images/mine/6x9h) | Molecular mechanism and structural basis of small-molecule modulation of acid-sensing ion channel 1 (ASIC1) | 分子名称: | 2-[4-(3,4-dimethoxyphenoxy)phenyl]-1H-benzimidazole-6-carboximidamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, ... | 著者 | Liu, Y, Ma, J, DesJarlais, R.L, Hagan, R, Rech, J, Lin, D, Liu, C, Miller, R, Schoellerman, J, Luo, J, Letavic, M, Grasberger, B, Maher, M. | 登録日 | 2020-06-02 | 公開日 | 2020-12-30 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | 主引用文献 | Molecular mechanism and structural basis of small-molecule modulation of the gating of acid-sensing ion channel 1. Commun Biol, 4, 2021
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2LUJ
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![BU of 2luj by Molmil](/molmil-images/mine/2luj) | Solution structure of a parallel-stranded oligoisoguanine DNA pentaplex formed by d(T(iG)4T) in the presence of Cs ions | 分子名称: | DNA (5'-D(*TP*(IGU)P*(IGU)P*(IGU)P*(IGU)P*T)-3') | 著者 | Kang, M, Heuberger, B, Chaput, J.C, Switzer, C, Feigon, J. | 登録日 | 2012-06-14 | 公開日 | 2012-07-25 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of a Parallel-Stranded Oligoisoguanine DNA Pentaplex Formed by d(T(iG)4T) in the Presence of Cs(+) Ions. Angew.Chem.Int.Ed.Engl., 51, 2012
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5ZGG
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![BU of 5zgg by Molmil](/molmil-images/mine/5zgg) | |
6E6B
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![BU of 6e6b by Molmil](/molmil-images/mine/6e6b) | Crystal structure of the Protocadherin GammaB4 extracellular domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Goodman, K.M, Mannepalli, S, Bahna, F, Honig, B, Shapiro, L. | 登録日 | 2018-07-24 | 公開日 | 2019-04-10 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (4.52 Å) | 主引用文献 | Visualization of clustered protocadherin neuronal self-recognition complexes. Nature, 569, 2019
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7AYI
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![BU of 7ayi by Molmil](/molmil-images/mine/7ayi) | Crystal structure of Aurora A in complex with 7-(2-Anilinopyrimidin-4-yl)-1-benzazepin-2-one derivative (compound 2a) | 分子名称: | 7-(2-phenylazanylpyrimidin-4-yl)-1,3,4,5-tetrahydro-1-benzazepin-2-one, Aurora kinase A | 著者 | Chaikuad, A, Karatas, M, Kunick, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2020-11-12 | 公開日 | 2021-01-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | 主引用文献 | 7-(2-Anilinopyrimidin-4-yl)-1-benzazepin-2-ones Designed by a "Cut and Glue" Strategy Are Dual Aurora A/VEGF-R Kinase Inhibitors. Molecules, 26, 2021
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7AYH
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![BU of 7ayh by Molmil](/molmil-images/mine/7ayh) | Crystal structure of Aurora A in complex with 7-(2-Anilinopyrimidin-4-yl)-1-benzazepin-2-one derivative (compound 2c) | 分子名称: | 7-[2-[(4-methoxyphenyl)amino]pyrimidin-4-yl]-1,3,4,5-tetrahydro-1-benzazepin-2-one, Aurora kinase A | 著者 | Chaikuad, A, Karatas, M, Kunick, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2020-11-12 | 公開日 | 2021-01-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | 7-(2-Anilinopyrimidin-4-yl)-1-benzazepin-2-ones Designed by a "Cut and Glue" Strategy Are Dual Aurora A/VEGF-R Kinase Inhibitors. Molecules, 26, 2021
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7ZQY
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![BU of 7zqy by Molmil](/molmil-images/mine/7zqy) | |
7ZR1
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![BU of 7zr1 by Molmil](/molmil-images/mine/7zr1) | Chaetomium thermophilum Mre11-Rad50-Nbs1 complex bound to ATPyS (composite structure) | 分子名称: | DH domain-containing protein, Double-strand break repair protein, FHA domain-containing protein, ... | 著者 | Bartho, J.D, Rotheneder, M, Stakyte, K, Lammens, K, Hopfner, K.P. | 登録日 | 2022-05-03 | 公開日 | 2023-01-11 | 最終更新日 | 2023-12-13 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions. Mol.Cell, 83, 2023
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7P2Q
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![BU of 7p2q by Molmil](/molmil-images/mine/7p2q) | Human Signal Peptidase Complex Paralog C (SPC-C) | 分子名称: | Signal peptidase complex catalytic subunit SEC11C, Signal peptidase complex subunit 1, Signal peptidase complex subunit 2, ... | 著者 | Liaci, A.M, Foerster, F. | 登録日 | 2021-07-06 | 公開日 | 2021-10-06 | 最終更新日 | 2022-12-21 | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | 主引用文献 | Structure of the human signal peptidase complex reveals the determinants for signal peptide cleavage. Mol.Cell, 81, 2021
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7P2P
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![BU of 7p2p by Molmil](/molmil-images/mine/7p2p) | Human Signal Peptidase Complex Paralog A (SPC-A) | 分子名称: | Signal peptidase complex catalytic subunit SEC11A, Signal peptidase complex subunit 1, Signal peptidase complex subunit 2, ... | 著者 | Liaci, A.M, Foerster, F. | 登録日 | 2021-07-06 | 公開日 | 2021-10-06 | 最終更新日 | 2022-12-21 | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | 主引用文献 | Structure of the human signal peptidase complex reveals the determinants for signal peptide cleavage. Mol.Cell, 81, 2021
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4U34
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![BU of 4u34 by Molmil](/molmil-images/mine/4u34) | Crystal Structures of RNA Duplexes Containing 2-thio-Uridine | 分子名称: | RNA (5'-R(*GP*GP*AP*GP*CP*UP*A)-3'), RNA (5'-R(*UP*AP*GP*CP*(SUR)P*CP*C-3') | 著者 | Sheng, J, Larsen, A, Heuberger, B, Blain, J.C, Szostak, J.W. | 登録日 | 2014-07-18 | 公開日 | 2014-08-13 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Crystal Structure Studies of RNA Duplexes Containing s(2)U:A and s(2)U:U Base Pairs. J.Am.Chem.Soc., 136, 2014
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4U38
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![BU of 4u38 by Molmil](/molmil-images/mine/4u38) | RNA duplex containing UU mispair | 分子名称: | RNA (5'-R(*GP*GP*UP*GP*CP*UP*A)-3'), RNA (5'-R(*UP*AP*GP*CP*UP*CP*C)-3') | 著者 | Sheng, J, Larsen, A, Heuberger, B, Blain, J.C, Szostak, J.W. | 登録日 | 2014-07-18 | 公開日 | 2014-08-13 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structure Studies of RNA Duplexes Containing s(2)U:A and s(2)U:U Base Pairs. J.Am.Chem.Soc., 136, 2014
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4U35
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![BU of 4u35 by Molmil](/molmil-images/mine/4u35) | Crystal Structures of RNA Duplexes Containing 2-thio-Uridine | 分子名称: | RNA (5'-R(*GP*GP*UP*GP*CP*UP*A)-3'), RNA (5'-R(*UP*AP*GP*CP*(SUR)P*CP*C-3') | 著者 | Sheng, J, Larsen, A, Heuberger, B, Blain, J.C, Szostak, J.W. | 登録日 | 2014-07-18 | 公開日 | 2014-08-13 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Crystal Structure Studies of RNA Duplexes Containing s(2)U:A and s(2)U:U Base Pairs. J.Am.Chem.Soc., 136, 2014
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4U37
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![BU of 4u37 by Molmil](/molmil-images/mine/4u37) | Native 7mer-RNA duplex | 分子名称: | RNA (5'-R(*GP*GP*AP*GP*CP*UP*A)-3'), RNA (5'-R(*UP*AP*GP*CP*UP*CP*C)-3') | 著者 | Sheng, J, Larsen, A, Heuberger, B, Blain, J.C, Szostak, J.W. | 登録日 | 2014-07-18 | 公開日 | 2014-08-13 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Crystal Structure Studies of RNA Duplexes Containing s(2)U:A and s(2)U:U Base Pairs. J.Am.Chem.Soc., 136, 2014
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8BAH
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![BU of 8bah by Molmil](/molmil-images/mine/8bah) | Human Mre11-Nbs1 complex | 分子名称: | Double-strand break repair protein MRE11, MANGANESE (II) ION, Nibrin | 著者 | Bartho, J.D, Rotheneder, M, Stakyte, K, Lammens, K, Hopfner, K.P. | 登録日 | 2022-10-11 | 公開日 | 2023-01-11 | 最終更新日 | 2023-12-13 | 実験手法 | ELECTRON MICROSCOPY (4.13 Å) | 主引用文献 | Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions. Mol.Cell, 83, 2023
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