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2X79
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BU of 2x79 by Molmil
Inward facing conformation of Mhp1
分子名称: HYDANTOIN TRANSPORT PROTEIN
著者Shimamura, T, Weyand, S, Beckstein, O, Rutherford, N.G, Hadden, J.M, Sharples, D, Sansom, M.S.P, Iwata, S, Henderson, P.J.F, Cameron, A.D.
登録日2010-02-25
公開日2010-05-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Molecular Basis of Alternating Access Membrane Transport by the Sodium-Hydantoin Transporter Mhp1.
Science, 328, 2010
5SV9
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BU of 5sv9 by Molmil
Structure of the SLC4 transporter Bor1p in an inward-facing conformation
分子名称: Bor1p boron transporter
著者Coudray, N, Seyler, S, Lasala, R, Zhang, Z, Clark, K.M, Dumont, M.E, Rohou, A, Beckstein, O, Stokes, D.L, Transcontinental EM Initiative for Membrane Protein Structure (TEMIMPS)
登録日2016-08-05
公開日2016-08-17
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (5.9 Å)
主引用文献Structure of the SLC4 transporter Bor1p in an inward-facing conformation.
Protein Sci., 26, 2017
7KZX
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BU of 7kzx by Molmil
Cryo-EM structure of YiiP-Fab complex in Apo state
分子名称: Cadmium and zinc efflux pump FieF, Fab2R heavy chain, Fab2R light chain
著者Lopez-Redondo, M.L, Fan, S, Koide, A, Koide, S, Beckstein, O, Stokes, D.L.
登録日2020-12-10
公開日2021-01-06
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Zinc binding alters the conformational dynamics and drives the transport cycle of the cation diffusion facilitator YiiP.
J.Gen.Physiol., 153, 2021
7KZZ
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BU of 7kzz by Molmil
Cryo-EM structure of YiiP-Fab complex in Holo state
分子名称: Cadmium and zinc efflux pump FieF, Fab2R heavy chain, Fab2R light chain, ...
著者Lopez-Redondo, M.L, Fan, S, Koide, A, Koide, S, Beckstein, O, Stokes, D.L.
登録日2020-12-10
公開日2021-01-06
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献Zinc binding alters the conformational dynamics and drives the transport cycle of the cation diffusion facilitator YiiP.
J.Gen.Physiol., 153, 2021
7S24
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BU of 7s24 by Molmil
Crystal structure of the Na+/H+ antiporter NhaA at pH 6.5
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Na(+)/H(+) antiporter NhaA, PENTAETHYLENE GLYCOL
著者Drew, D, Brock, J, Uzdavinys, P, Matsuoka, R.
登録日2021-09-03
公開日2022-08-10
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the Na + /H + antiporter NhaA at active pH reveals the mechanistic basis for pH sensing.
Nat Commun, 13, 2022
8OYG
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BU of 8oyg by Molmil
Crystal structure of ASBTNM in complex with pantoate
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CADMIUM ION, PANTOATE, ...
著者Becker, P, Cameron, A.D.
登録日2023-05-04
公開日2023-07-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Mechanism of substrate binding and transport in BASS transporters.
Biorxiv, 2023
8OYF
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BU of 8oyf by Molmil
Crystal structure of ASBTNM in lipidic cubic phase without substrate bound
分子名称: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, NICKEL (II) ION, PHOSPHATIDYLETHANOLAMINE, ...
著者Becker, P, Cameron, A.D.
登録日2023-05-04
公開日2023-07-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Mechanism of substrate binding and transport in BASS transporters.
Biorxiv, 2023
6HOO
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BU of 6hoo by Molmil
Crystal Structure of Rationally Designed OXA-48loop18 beta-lactamase
分子名称: Beta-lactamase,OXA-48loop18,Beta-lactamase, FLUORIDE ION, GLYCEROL, ...
著者Zavala, A, Retailleau, P, Dabos, L, Naas, T, Iorga, B.
登録日2018-09-17
公開日2019-10-09
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Substrate Specificity of OXA-48 after beta 5-beta 6 Loop Replacement.
Acs Infect Dis., 6, 2020
6I5D
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BU of 6i5d by Molmil
Crystal structure of an OXA-48 beta-lactamase synthetic mutant
分子名称: 1,2-ETHANEDIOL, Beta-lactamase, CHLORIDE ION, ...
著者Zavala, A, Retailleau, P, Dabos, L, Naas, T, Iorga, B.
登録日2018-11-13
公開日2020-03-04
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Substrate specificity of an OXA-48 beta-lactamase synthetic mutant
To be published
6Z3Y
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BU of 6z3y by Molmil
CryoEM structure of horse sodium/proton exchanger NHE9 in an inward-facing conformation
分子名称: Sodium/hydrogen exchanger
著者Winkelmannm, I, Matsuoka, R, Meier, P, Drew, D.
登録日2020-05-22
公開日2020-11-04
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.51 Å)
主引用文献Structure and elevator mechanism of the mammalian sodium/proton exchanger NHE9.
Embo J., 39, 2020
6Z3Z
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CryoEM structure of horse sodium/proton exchanger NHE9 without C-terminal regulatory domain in an inward-facing conformation
分子名称: Sodium/hydrogen exchanger
著者Winkelmann, I, Matsuoka, R, Meier, P, Drew, D.
登録日2020-05-22
公開日2020-11-04
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.19 Å)
主引用文献Structure and elevator mechanism of the mammalian sodium/proton exchanger NHE9.
Embo J., 39, 2020
5BZ3
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BU of 5bz3 by Molmil
CRYSTAL STRUCTURE OF SODIUM PROTON ANTIPORTER NAPA IN OUTWARD-FACING CONFORMATION.
分子名称: (2R)-2,3-DIHYDROXYPROPYL (7Z)-TETRADEC-7-ENOATE, Na(+)/H(+) antiporter
著者Coincon, M, Uzdavinys, P, Emmanuel, N, Cameron, A, Drew, D.
登録日2015-06-11
公開日2016-01-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures reveal the molecular basis of ion translocation in sodium/proton antiporters.
Nat.Struct.Mol.Biol., 23, 2016
5BZ2
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BU of 5bz2 by Molmil
CRYSTAL STRUCTURE OF THE SODIUM PROTON ANTIPORTER NAPA IN INWARD-FACING CONFORMATION
分子名称: Na(+)/H(+) antiporter
著者Coincon, M, Uzdavinys, P, Cameron, A, Drew, D.
登録日2015-06-11
公開日2016-01-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Crystal structures reveal the molecular basis of ion translocation in sodium/proton antiporters.
Nat.Struct.Mol.Biol., 23, 2016
7P1J
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BU of 7p1j by Molmil
Cryo EM structure of bison NHA2 in detergent structure
分子名称: mitochondrial sodium/hydrogen exchanger 9B2
著者Matsuoka, R, Fudim, R, Jung, S, Drew, D.
登録日2021-07-01
公開日2022-01-26
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献Structure, mechanism and lipid-mediated remodeling of the mammalian Na + /H + exchanger NHA2.
Nat.Struct.Mol.Biol., 29, 2022
7P1I
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BU of 7p1i by Molmil
Cryo EM structure of bison NHA2 in detergent and N-terminal extension helix
分子名称: mitochondrial sodium/hydrogen exchanger 9B2
著者Matsuoka, R, Fudim, R, Jung, S, Drew, D.
登録日2021-07-01
公開日2022-01-26
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献Structure, mechanism and lipid-mediated remodeling of the mammalian Na + /H + exchanger NHA2.
Nat.Struct.Mol.Biol., 29, 2022
7P1K
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BU of 7p1k by Molmil
Cryo EM structure of bison NHA2 in nano disc structure
分子名称: CHOLESTEROL HEMISUCCINATE, Phosphatidylinositol, mitochondrial sodium/hydrogen exchanger 9B2
著者Matsuoka, R, Fudim, R, Jung, S, Drew, D.
登録日2021-07-01
公開日2022-01-26
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.64 Å)
主引用文献Structure, mechanism and lipid-mediated remodeling of the mammalian Na + /H + exchanger NHA2.
Nat.Struct.Mol.Biol., 29, 2022
4ATV
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BU of 4atv by Molmil
STRUCTURE OF A TRIPLE MUTANT OF THE NHAA DIMER, CRYSTALLISED AT LOW PH
分子名称: DODECYL-ALPHA-D-MALTOSIDE, NA(+)/H(+) ANTIPORTER NHAA, SULFATE ION
著者Drew, D, Lee, C, Iwata, S, Cameron, A.D.
登録日2012-05-10
公開日2013-07-10
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Crystal structure of the sodium-proton antiporter NhaA dimer and new mechanistic insights.
J. Gen. Physiol., 144, 2014
4AU5
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BU of 4au5 by Molmil
Structure of the NhaA dimer, crystallised at low pH
分子名称: DODECYL-ALPHA-D-MALTOSIDE, NA(+)/H(+) ANTIPORTER NHAA, SULFATE ION
著者Drew, D, Lee, C, Iwata, S, Cameron, A.D.
登録日2012-05-14
公開日2013-07-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.696 Å)
主引用文献Crystal structure of the sodium-proton antiporter NhaA dimer and new mechanistic insights.
J. Gen. Physiol., 144, 2014
4D1C
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BU of 4d1c by Molmil
STRUCTURE OF MHP1, A NUCLEOBASE-CATION-SYMPORT-1 FAMILY TRANSPORTER, IN A CLOSED CONFORMATION WITH bromovinylhydantoin bound.
分子名称: (5Z)-5-[(3-bromophenyl)methylidene]imidazolidine-2,4-dione, HYDANTOIN TRANSPORT PROTEIN, SODIUM ION
著者Weyand, S, Brueckner, F, Geng, T, Drew, D, Iwata, S, Henderson, P.J.F, Cameron, A.D.
登録日2014-05-01
公開日2014-07-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Molecular Mechanism of Ligand Recognition by Membrane Transport Protein, Mhp1.
Embo J., 33, 2014
4D1D
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BU of 4d1d by Molmil
STRUCTURE OF MHP1, A NUCLEOBASE-CATION-SYMPORT-1 FAMILY TRANSPORTER with the inhibitor 5-(2-naphthylmethyl)-L-hydantoin.
分子名称: 5-(2-NAPHTHYLMETHYL)-D-HYDANTOIN, 5-(2-NAPHTHYLMETHYL)-L-HYDANTOIN, HYDANTOIN TRANSPORT PROTEIN, ...
著者Weyand, S, Brueckner, F, Geng, T, Drew, D, Iwata, S, Henderson, P.J.F, Cameron, A.D.
登録日2014-05-01
公開日2014-07-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Molecular Mechanism of Ligand Recognition by Membrane Transport Protein, Mhp1.
Embo J., 33, 2014
4D1A
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BU of 4d1a by Molmil
STRUCTURE OF MHP1, A NUCLEOBASE-CATION-SYMPORT-1 FAMILY TRANSPORTER, IN A CLOSED CONFORMATION WITH INDOLYLMETHYL-HYDANTOIN
分子名称: (5S)-5-(1H-indol-3-ylmethyl)imidazolidine-2,4-dione, HYDANTOIN TRANSPORT PROTEIN, SODIUM ION
著者Weyand, S, Brueckner, F, Geng, T, Drew, D, Iwata, S, Henderson, P.J.F, Cameron, A.D.
登録日2014-05-01
公開日2014-07-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Molecular Mechanism of Ligand Recognition by Membrane Transport Protein, Mhp1.
Embo J., 33, 2014
4D1B
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BU of 4d1b by Molmil
STRUCTURE OF MHP1, A NUCLEOBASE-CATION-SYMPORT-1 FAMILY TRANSPORTER, IN A CLOSED CONFORMATION WITH BENZYL-HYDANTOIN
分子名称: (5S)-5-benzylimidazolidine-2,4-dione, HYDANTOIN TRANSPORT PROTEIN, SODIUM ION
著者Brueckner, F, Geng, T, Weyand, S, Drew, D, Iwata, S, Henderson, P.J.F, Cameron, A.D.
登録日2014-05-01
公開日2014-07-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Molecular Mechanism of Ligand Recognition by Membrane Transport Protein, Mhp1.
Embo J., 33, 2014
4BWZ
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Crystal structure of the sodium proton antiporter, NapA
分子名称: NA(+)/H(+) ANTIPORTER, ZINC ION
著者Lee, C, Drew, D, Cameron, A.D.
登録日2013-07-05
公開日2013-08-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.984 Å)
主引用文献A two-domain elevator mechanism for sodium/proton antiport.
Nature, 501, 2013

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