2X79
| Inward facing conformation of Mhp1 | 分子名称: | HYDANTOIN TRANSPORT PROTEIN | 著者 | Shimamura, T, Weyand, S, Beckstein, O, Rutherford, N.G, Hadden, J.M, Sharples, D, Sansom, M.S.P, Iwata, S, Henderson, P.J.F, Cameron, A.D. | 登録日 | 2010-02-25 | 公開日 | 2010-05-05 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Molecular Basis of Alternating Access Membrane Transport by the Sodium-Hydantoin Transporter Mhp1. Science, 328, 2010
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5SV9
| Structure of the SLC4 transporter Bor1p in an inward-facing conformation | 分子名称: | Bor1p boron transporter | 著者 | Coudray, N, Seyler, S, Lasala, R, Zhang, Z, Clark, K.M, Dumont, M.E, Rohou, A, Beckstein, O, Stokes, D.L, Transcontinental EM Initiative for Membrane Protein Structure (TEMIMPS) | 登録日 | 2016-08-05 | 公開日 | 2016-08-17 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (5.9 Å) | 主引用文献 | Structure of the SLC4 transporter Bor1p in an inward-facing conformation. Protein Sci., 26, 2017
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7KZX
| Cryo-EM structure of YiiP-Fab complex in Apo state | 分子名称: | Cadmium and zinc efflux pump FieF, Fab2R heavy chain, Fab2R light chain | 著者 | Lopez-Redondo, M.L, Fan, S, Koide, A, Koide, S, Beckstein, O, Stokes, D.L. | 登録日 | 2020-12-10 | 公開日 | 2021-01-06 | 最終更新日 | 2021-07-28 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Zinc binding alters the conformational dynamics and drives the transport cycle of the cation diffusion facilitator YiiP. J.Gen.Physiol., 153, 2021
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7KZZ
| Cryo-EM structure of YiiP-Fab complex in Holo state | 分子名称: | Cadmium and zinc efflux pump FieF, Fab2R heavy chain, Fab2R light chain, ... | 著者 | Lopez-Redondo, M.L, Fan, S, Koide, A, Koide, S, Beckstein, O, Stokes, D.L. | 登録日 | 2020-12-10 | 公開日 | 2021-01-06 | 最終更新日 | 2021-07-28 | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | 主引用文献 | Zinc binding alters the conformational dynamics and drives the transport cycle of the cation diffusion facilitator YiiP. J.Gen.Physiol., 153, 2021
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7S24
| Crystal structure of the Na+/H+ antiporter NhaA at pH 6.5 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Na(+)/H(+) antiporter NhaA, PENTAETHYLENE GLYCOL | 著者 | Drew, D, Brock, J, Uzdavinys, P, Matsuoka, R. | 登録日 | 2021-09-03 | 公開日 | 2022-08-10 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of the Na + /H + antiporter NhaA at active pH reveals the mechanistic basis for pH sensing. Nat Commun, 13, 2022
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8OYG
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8OYF
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6HOO
| Crystal Structure of Rationally Designed OXA-48loop18 beta-lactamase | 分子名称: | Beta-lactamase,OXA-48loop18,Beta-lactamase, FLUORIDE ION, GLYCEROL, ... | 著者 | Zavala, A, Retailleau, P, Dabos, L, Naas, T, Iorga, B. | 登録日 | 2018-09-17 | 公開日 | 2019-10-09 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Substrate Specificity of OXA-48 after beta 5-beta 6 Loop Replacement. Acs Infect Dis., 6, 2020
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6I5D
| Crystal structure of an OXA-48 beta-lactamase synthetic mutant | 分子名称: | 1,2-ETHANEDIOL, Beta-lactamase, CHLORIDE ION, ... | 著者 | Zavala, A, Retailleau, P, Dabos, L, Naas, T, Iorga, B. | 登録日 | 2018-11-13 | 公開日 | 2020-03-04 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Substrate specificity of an OXA-48 beta-lactamase synthetic mutant To be published
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6Z3Y
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6Z3Z
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5BZ3
| CRYSTAL STRUCTURE OF SODIUM PROTON ANTIPORTER NAPA IN OUTWARD-FACING CONFORMATION. | 分子名称: | (2R)-2,3-DIHYDROXYPROPYL (7Z)-TETRADEC-7-ENOATE, Na(+)/H(+) antiporter | 著者 | Coincon, M, Uzdavinys, P, Emmanuel, N, Cameron, A, Drew, D. | 登録日 | 2015-06-11 | 公開日 | 2016-01-20 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structures reveal the molecular basis of ion translocation in sodium/proton antiporters. Nat.Struct.Mol.Biol., 23, 2016
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5BZ2
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7P1J
| Cryo EM structure of bison NHA2 in detergent structure | 分子名称: | mitochondrial sodium/hydrogen exchanger 9B2 | 著者 | Matsuoka, R, Fudim, R, Jung, S, Drew, D. | 登録日 | 2021-07-01 | 公開日 | 2022-01-26 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | 主引用文献 | Structure, mechanism and lipid-mediated remodeling of the mammalian Na + /H + exchanger NHA2. Nat.Struct.Mol.Biol., 29, 2022
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7P1I
| Cryo EM structure of bison NHA2 in detergent and N-terminal extension helix | 分子名称: | mitochondrial sodium/hydrogen exchanger 9B2 | 著者 | Matsuoka, R, Fudim, R, Jung, S, Drew, D. | 登録日 | 2021-07-01 | 公開日 | 2022-01-26 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | 主引用文献 | Structure, mechanism and lipid-mediated remodeling of the mammalian Na + /H + exchanger NHA2. Nat.Struct.Mol.Biol., 29, 2022
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7P1K
| Cryo EM structure of bison NHA2 in nano disc structure | 分子名称: | CHOLESTEROL HEMISUCCINATE, Phosphatidylinositol, mitochondrial sodium/hydrogen exchanger 9B2 | 著者 | Matsuoka, R, Fudim, R, Jung, S, Drew, D. | 登録日 | 2021-07-01 | 公開日 | 2022-01-26 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.64 Å) | 主引用文献 | Structure, mechanism and lipid-mediated remodeling of the mammalian Na + /H + exchanger NHA2. Nat.Struct.Mol.Biol., 29, 2022
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4ATV
| STRUCTURE OF A TRIPLE MUTANT OF THE NHAA DIMER, CRYSTALLISED AT LOW PH | 分子名称: | DODECYL-ALPHA-D-MALTOSIDE, NA(+)/H(+) ANTIPORTER NHAA, SULFATE ION | 著者 | Drew, D, Lee, C, Iwata, S, Cameron, A.D. | 登録日 | 2012-05-10 | 公開日 | 2013-07-10 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Crystal structure of the sodium-proton antiporter NhaA dimer and new mechanistic insights. J. Gen. Physiol., 144, 2014
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4AU5
| Structure of the NhaA dimer, crystallised at low pH | 分子名称: | DODECYL-ALPHA-D-MALTOSIDE, NA(+)/H(+) ANTIPORTER NHAA, SULFATE ION | 著者 | Drew, D, Lee, C, Iwata, S, Cameron, A.D. | 登録日 | 2012-05-14 | 公開日 | 2013-07-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.696 Å) | 主引用文献 | Crystal structure of the sodium-proton antiporter NhaA dimer and new mechanistic insights. J. Gen. Physiol., 144, 2014
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4D1C
| STRUCTURE OF MHP1, A NUCLEOBASE-CATION-SYMPORT-1 FAMILY TRANSPORTER, IN A CLOSED CONFORMATION WITH bromovinylhydantoin bound. | 分子名称: | (5Z)-5-[(3-bromophenyl)methylidene]imidazolidine-2,4-dione, HYDANTOIN TRANSPORT PROTEIN, SODIUM ION | 著者 | Weyand, S, Brueckner, F, Geng, T, Drew, D, Iwata, S, Henderson, P.J.F, Cameron, A.D. | 登録日 | 2014-05-01 | 公開日 | 2014-07-02 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Molecular Mechanism of Ligand Recognition by Membrane Transport Protein, Mhp1. Embo J., 33, 2014
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4D1D
| STRUCTURE OF MHP1, A NUCLEOBASE-CATION-SYMPORT-1 FAMILY TRANSPORTER with the inhibitor 5-(2-naphthylmethyl)-L-hydantoin. | 分子名称: | 5-(2-NAPHTHYLMETHYL)-D-HYDANTOIN, 5-(2-NAPHTHYLMETHYL)-L-HYDANTOIN, HYDANTOIN TRANSPORT PROTEIN, ... | 著者 | Weyand, S, Brueckner, F, Geng, T, Drew, D, Iwata, S, Henderson, P.J.F, Cameron, A.D. | 登録日 | 2014-05-01 | 公開日 | 2014-07-02 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Molecular Mechanism of Ligand Recognition by Membrane Transport Protein, Mhp1. Embo J., 33, 2014
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4D1A
| STRUCTURE OF MHP1, A NUCLEOBASE-CATION-SYMPORT-1 FAMILY TRANSPORTER, IN A CLOSED CONFORMATION WITH INDOLYLMETHYL-HYDANTOIN | 分子名称: | (5S)-5-(1H-indol-3-ylmethyl)imidazolidine-2,4-dione, HYDANTOIN TRANSPORT PROTEIN, SODIUM ION | 著者 | Weyand, S, Brueckner, F, Geng, T, Drew, D, Iwata, S, Henderson, P.J.F, Cameron, A.D. | 登録日 | 2014-05-01 | 公開日 | 2014-07-02 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Molecular Mechanism of Ligand Recognition by Membrane Transport Protein, Mhp1. Embo J., 33, 2014
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4D1B
| STRUCTURE OF MHP1, A NUCLEOBASE-CATION-SYMPORT-1 FAMILY TRANSPORTER, IN A CLOSED CONFORMATION WITH BENZYL-HYDANTOIN | 分子名称: | (5S)-5-benzylimidazolidine-2,4-dione, HYDANTOIN TRANSPORT PROTEIN, SODIUM ION | 著者 | Brueckner, F, Geng, T, Weyand, S, Drew, D, Iwata, S, Henderson, P.J.F, Cameron, A.D. | 登録日 | 2014-05-01 | 公開日 | 2014-07-02 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Molecular Mechanism of Ligand Recognition by Membrane Transport Protein, Mhp1. Embo J., 33, 2014
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4BWZ
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