2K31
| Solution Structure of cGMP-binding GAF domain of Phosphodiesterase 5 | 分子名称: | GUANOSINE-3',5'-MONOPHOSPHATE, Phosphodiesterase 5A, cGMP-specific | 著者 | Heikaus, C.C, Stout, J.R, Sekharan, M.R, Eakin, C.M, Rajagopal, P, Brzovic, P.S, Beavo, J.A, Klevit, R.E. | 登録日 | 2008-04-16 | 公開日 | 2008-06-03 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of the cGMP Binding GAF Domain from Phosphodiesterase 5: Insights into Nucleotide Selectivity, Dimerization, and cGMP-Dependent Conformational Change. J.Biol.Chem., 283, 2008
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3DBA
| Crystal structure of the cGMP-bound GAF a domain from the photoreceptor phosphodiesterase 6C | 分子名称: | Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha', GLYCEROL, GUANOSINE-3',5'-MONOPHOSPHATE | 著者 | Martinez, S.E, Heikaus, C.C, Klevit, R.E, Beavo, J.A. | 登録日 | 2008-05-30 | 公開日 | 2008-07-01 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | 主引用文献 | The Structure of the GAF A Domain from Phosphodiesterase 6C Reveals Determinants of cGMP Binding, a Conserved Binding Surface, and a Large cGMP-dependent Conformational Change. J.Biol.Chem., 283, 2008
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1YKD
| Crystal Structure of the Tandem GAF Domains from a Cyanobacterial Adenylyl Cyclase: Novel Modes of Ligand-Binding and Dimerization | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, adenylate cyclase | 著者 | Martinez, S.E, Bruder, S, Schultz, A, Zheng, N, Schultz, J.E, Beavo, J.A, Linder, J.U. | 登録日 | 2005-01-17 | 公開日 | 2005-02-22 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of the tandem GAF domains from a cyanobacterial adenylyl cyclase: Modes of ligand binding and dimerization Proc.Natl.Acad.Sci.USA, 102, 2005
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1MC0
| Regulatory Segment of Mouse 3',5'-Cyclic Nucleotide Phosphodiesterase 2A, Containing the GAF A and GAF B Domains | 分子名称: | 3',5'-cyclic nucleotide phosphodiesterase 2A, CYCLIC GUANOSINE MONOPHOSPHATE | 著者 | Martinez, S, Wu, A, Glavas, N, Tang, X, Turley, S, Hol, W, Beavo, J. | 登録日 | 2002-08-04 | 公開日 | 2002-10-02 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | 主引用文献 | The two GAF domains in phosphodiesterase 2A have distinct roles in dimerization and in cGMP binding. Proc.Natl.Acad.Sci.USA, 99, 2002
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