1K98
 
 | | AdoMet complex of MetH C-terminal fragment | | 分子名称: | COBALAMIN, Methionine synthase, SULFATE ION | | 著者 | Bandarian, V, Pattridge, K.A, Lennon, B.W, Huddler, D.P, Matthews, R.G, Ludwig, M.L. | | 登録日 | 2001-10-27 | | 公開日 | 2001-12-21 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3.75 Å) | | 主引用文献 | Domain alternation switches B(12)-dependent methionine synthase to the activation conformation.
Nat.Struct.Biol., 9, 2002
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1K7Y
 | | E. coli MetH C-terminal fragment (649-1227) | | 分子名称: | COBALAMIN, SULFATE ION, methionine synthase | | 著者 | Bandarian, V, Pattridge, K.A, Lennon, B.W, Huddler, D.P, Matthews, R.G, Ludwig, M.L. | | 登録日 | 2001-10-22 | | 公開日 | 2001-12-21 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Domain alternation switches B(12)-dependent methionine synthase to the activation conformation.
Nat.Struct.Biol., 9, 2002
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4NTM
 | | QueD soaked with sepiapterin (selenomethionine substituted protein) | | 分子名称: | (6R)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridine-6-carboxylic acid, 6-carboxy-5,6,7,8-tetrahydropterin synthase, ZINC ION | | 著者 | Bandarian, V, Miles, Z.D, Roberts, S.A. | | 登録日 | 2013-12-02 | | 公開日 | 2014-07-16 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Biochemical and Structural Studies of 6-Carboxy-5,6,7,8-tetrahydropterin Synthase Reveal the Molecular Basis of Catalytic Promiscuity within the Tunnel-fold Superfamily.
J.Biol.Chem., 289, 2014
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4NTN
 | | E.coli QueD, SeMet protein, 2A resolution | | 分子名称: | 6-carboxy-5,6,7,8-tetrahydropterin synthase, FORMIC ACID, ZINC ION | | 著者 | Bandarian, V, Roberts, S.A, Miles, Z.D. | | 登録日 | 2013-12-02 | | 公開日 | 2014-07-16 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Biochemical and Structural Studies of 6-Carboxy-5,6,7,8-tetrahydropterin Synthase Reveal the Molecular Basis of Catalytic Promiscuity within the Tunnel-fold Superfamily.
J.Biol.Chem., 289, 2014
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4NTK
 | | QueD from E. coli | | 分子名称: | 2-amino-6-[(1Z)-1,2-dihydroxyprop-1-en-1-yl]-7,8-dihydropteridin-4(3H)-one, 6-carboxy-5,6,7,8-tetrahydropterin synthase, ACETATE ION, ... | | 著者 | Bandarian, V, Roberts, S.A, Miles, Z.D. | | 登録日 | 2013-12-02 | | 公開日 | 2014-07-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Biochemical and Structural Studies of 6-Carboxy-5,6,7,8-tetrahydropterin Synthase Reveal the Molecular Basis of Catalytic Promiscuity within the Tunnel-fold Superfamily.
J.Biol.Chem., 289, 2014
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2QV6
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4NJI
 | | Crystal Structure of QueE from Burkholderia multivorans in complex with AdoMet, 6-carboxy-5,6,7,8-tetrahydropterin, and Mg2+ | | 分子名称: | (6R)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridine-6-carboxylic acid, 7-carboxy-7-deazaguanine synthase, IRON/SULFUR CLUSTER, ... | | 著者 | Dowling, D.P, Bruender, N.A, Young, A.P, McCarty, R.M, Bandarian, V, Drennan, C.L. | | 登録日 | 2013-11-10 | | 公開日 | 2013-12-25 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.197 Å) | | 主引用文献 | Radical SAM enzyme QueE defines a new minimal core fold and metal-dependent mechanism.
Nat.Chem.Biol., 10, 2014
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4NJH
 | | Crystal Structure of QueE from Burkholderia multivorans in complex with AdoMet and 6-carboxy-5,6,7,8-tetrahydropterin | | 分子名称: | (6R)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridine-6-carboxylic acid, 7-carboxy-7-deazaguanine synthase, IRON/SULFUR CLUSTER, ... | | 著者 | Dowling, D.P, Bruender, N.A, Young, A.P, McCarty, R.M, Bandarian, V, Drennan, C.L. | | 登録日 | 2013-11-10 | | 公開日 | 2013-12-25 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.898 Å) | | 主引用文献 | Radical SAM enzyme QueE defines a new minimal core fold and metal-dependent mechanism.
Nat.Chem.Biol., 10, 2014
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3D7J
 | | SCO6650, a 6-pyruvoyltetrahydropterin synthase homolog from Streptomyces coelicolor | | 分子名称: | CHLORIDE ION, SODIUM ION, Uncharacterized protein SCO6650 | | 著者 | Spoonamore, J.E, Roberts, S.A, Heroux, A, Bandarian, V. | | 登録日 | 2008-05-21 | | 公開日 | 2008-10-21 | | 最終更新日 | 2012-03-28 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structure of a 6-pyruvoyltetrahydropterin synthase homolog from Streptomyces coelicolor.
Acta Crystallogr.,Sect.F, 64, 2008
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5T8Y
 | | Structure of epoxyqueuosine reductase from Bacillus subtilis with the Asp134 catalytic loop swung out of the active site. | | 分子名称: | COBALAMIN, Epoxyqueuosine reductase, IRON/SULFUR CLUSTER, ... | | 著者 | Dowling, D.P, Miles, Z.D, Kohrer, C, Maiocco, S.J, Elliott, S.J, Bandarian, V, Drennan, C.L. | | 登録日 | 2016-09-08 | | 公開日 | 2016-09-28 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.653 Å) | | 主引用文献 | Molecular basis of cobalamin-dependent RNA modification.
Nucleic Acids Res., 44, 2016
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5D08
 | | Crystal structure of selenomethionine-labeled epoxyqueuosine reductase | | 分子名称: | CHLORIDE ION, COBALAMIN, Epoxyqueuosine reductase, ... | | 著者 | Dowling, D.P, Miles, Z.D, Kohrer, C, Bandarian, V, Drennan, C.L. | | 登録日 | 2015-08-02 | | 公開日 | 2016-09-28 | | 最終更新日 | 2019-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.747 Å) | | 主引用文献 | Molecular basis of cobalamin-dependent RNA modification.
Nucleic Acids Res., 44, 2016
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5D0A
 | | Crystal structure of epoxyqueuosine reductase with cleaved RNA stem loop | | 分子名称: | COBALAMIN, Epoxyqueuosine reductase, GLYCEROL, ... | | 著者 | Dowling, D.P, Miles, Z.D, Kohrer, C, Bandarian, V, Drennan, C.L. | | 登録日 | 2015-08-03 | | 公開日 | 2016-09-28 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Molecular basis of cobalamin-dependent RNA modification.
Nucleic Acids Res., 44, 2016
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5D0B
 | | Crystal structure of epoxyqueuosine reductase with a tRNA-TYR epoxyqueuosine-modified tRNA stem loop | | 分子名称: | COBALAMIN, Epoxyqueuosine reductase, GLYCEROL, ... | | 著者 | Dowling, D.P, Miles, Z.D, Kohrer, C, Bandarian, V, Drennan, C.L. | | 登録日 | 2015-08-03 | | 公開日 | 2016-09-28 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.645 Å) | | 主引用文献 | Molecular basis of cobalamin-dependent RNA modification.
Nucleic Acids Res., 44, 2016
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4NJK
 | | Crystal Structure of QueE from Burkholderia multivorans in complex with AdoMet, 7-carboxy-7-deazaguanine, and Mg2+ | | 分子名称: | 2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carboxylic acid, 7-carboxy-7-deazaguanine synthase, IRON/SULFUR CLUSTER, ... | | 著者 | Dowling, D.P, Bruender, N.A, Young, A.P, McCarty, R.M, Bandarian, V, Drennan, C.L. | | 登録日 | 2013-11-10 | | 公開日 | 2013-12-25 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.911 Å) | | 主引用文献 | Radical SAM enzyme QueE defines a new minimal core fold and metal-dependent mechanism.
Nat.Chem.Biol., 10, 2014
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4NJJ
 | | Crystal Structure of QueE from Burkholderia multivorans in complex with AdoMet, 6-carboxy-5,6,7,8-tetrahydropterin, and Manganese(II) | | 分子名称: | (6R)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridine-6-carboxylic acid, 7-carboxy-7-deazaguanine synthase, IRON/SULFUR CLUSTER, ... | | 著者 | Dowling, D.P, Bruender, N.A, Young, A.P, McCarty, R.M, Bandarian, V, Drennan, C.L. | | 登録日 | 2013-11-10 | | 公開日 | 2013-12-25 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Radical SAM enzyme QueE defines a new minimal core fold and metal-dependent mechanism.
Nat.Chem.Biol., 10, 2014
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4NJG
 | | Crystal Structure of QueE from Burkholderia multivorans in complex with AdoMet and 6-carboxypterin | | 分子名称: | 6-CARBOXYPTERIN, 7-carboxy-7-deazaguanine synthase, IRON/SULFUR CLUSTER, ... | | 著者 | Dowling, D.P, Bruender, N.A, Young, A.P, McCarty, R.M, Bandarian, V, Drennan, C.L. | | 登録日 | 2013-11-10 | | 公開日 | 2013-12-25 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.598 Å) | | 主引用文献 | Radical SAM enzyme QueE defines a new minimal core fold and metal-dependent mechanism.
Nat.Chem.Biol., 10, 2014
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6DJT
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6NHL
 | | Crystal structure of QueE from Escherichia coli | | 分子名称: | 7-carboxy-7-deazaguanine synthase, DI(HYDROXYETHYL)ETHER, FE (III) ION, ... | | 著者 | Grell, T.A.J, Bell, B.N, Nguyen, C, Dowling, D.P, Drennan, C.L. | | 登録日 | 2018-12-23 | | 公開日 | 2019-01-16 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | | 主引用文献 | Crystal structure of AdoMet radical enzyme 7-carboxy-7-deazaguanine synthase from Escherichia coli suggests how modifications near [4Fe-4S] cluster engender flavodoxin specificity.
Protein Sci., 28, 2019
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3Q51
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3Q50
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3GCA
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6EFN
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5TGS
 | | Crystal Structure of QueE from Bacillus subtilis with methionine bound | | 分子名称: | 7-carboxy-7-deazaguanine synthase, DI(HYDROXYETHYL)ETHER, IRON/SULFUR CLUSTER, ... | | 著者 | Grell, T.A.J, Dowling, D.P, Drennan, C.L. | | 登録日 | 2016-09-28 | | 公開日 | 2017-01-18 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.548 Å) | | 主引用文献 | 7-Carboxy-7-deazaguanine Synthase: A Radical S-Adenosyl-l-methionine Enzyme with Polar Tendencies.
J. Am. Chem. Soc., 139, 2017
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5TH5
 | | Crystal Structure of QueE from Bacillus subtilis with 6-carboxypterin-5'-deoxyadenosyl ester bound | | 分子名称: | 5'-O-(2-amino-4-oxo-1,4-dihydropteridine-6-carbonyl)adenosine, 7-carboxy-7-deazaguanine synthase, IRON/SULFUR CLUSTER, ... | | 著者 | Grell, T.A.J, Dowling, D.P, Drennan, C.L. | | 登録日 | 2016-09-29 | | 公開日 | 2017-01-18 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.407 Å) | | 主引用文献 | 7-Carboxy-7-deazaguanine Synthase: A Radical S-Adenosyl-l-methionine Enzyme with Polar Tendencies.
J. Am. Chem. Soc., 139, 2017
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4Q6X
 | | Structure of phospholipase D Beta1B1i from Sicarius terrosus venom at 2.14 A resolution | | 分子名称: | MAGNESIUM ION, Phospholipase D StSicTox-betaIC1 | | 著者 | Lajoie, D.M, Roberts, S.A, Zobel-Thropp, P.A, Binford, G.J, Cordes, M.H. | | 登録日 | 2014-04-23 | | 公開日 | 2015-03-18 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Variable Substrate Preference among Phospholipase D Toxins from Sicariid Spiders.
J.Biol.Chem., 290, 2015
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