2H6R
 
 | | Crystal Structure of triosephosphate isomerase (TIM) from Methanocaldococcus jannaschii | | 分子名称: | Triosephosphate isomerase | | 著者 | Gayathri, P, Banerjee, M, Vijayalakshmi, A, Balaram, H, Balaram, P, Murthy, M.R.N. | | 登録日 | 2006-06-01 | | 公開日 | 2007-02-06 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of triosephosphate isomerase (TIM) from Methanocaldococcus jannaschii
Acta Crystallogr.,Sect.D, 63, 2007
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1M7O
 | | Plasmodium Falciparum Triosephosphate isomerase (PfTIM) compled to substrate analog 3-phosphoglycerate (3PG) | | 分子名称: | 3-PHOSPHOGLYCERIC ACID, Triosephosphate Isomerase | | 著者 | Parthasarathy, S, Balaram, H, Balaram, P, Murthy, M.R.N. | | 登録日 | 2002-07-22 | | 公開日 | 2002-11-29 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structures of Plasmodium falciparum triosephosphate isomerase complexed to substrate analogues: observation of the catalytic loop in the open conformation in the ligand-bound state.
Acta Crystallogr.,Sect.D, 58, 2002
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1M7P
 | | Plasmodium Falciparum Triosephosphate isomerase (PfTIM) compled to substrate analog glycerol-3-phosphate (G3P). | | 分子名称: | GLYCERALDEHYDE-3-PHOSPHATE, Triosephosphate Isomerase | | 著者 | Parthasarathy, S, Balaram, H, Balaram, P, Murthy, M.R.N. | | 登録日 | 2002-07-22 | | 公開日 | 2002-11-29 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structures of Plasmodium falciparum triosephosphate isomerase complexed to substrate analogues: observation of the catalytic loop in the open conformation in the ligand-bound state.
Acta Crystallogr.,Sect.D, 58, 2002
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1LYX
 | | Plasmodium Falciparum Triosephosphate Isomerase (PfTIM)-Phosphoglycolate complex | | 分子名称: | 2-PHOSPHOGLYCOLIC ACID, Triosephosphate Isomerase | | 著者 | Parthasarathy, S, Balaram, H, Balaram, P, Murthy, M.R. | | 登録日 | 2002-06-10 | | 公開日 | 2003-01-28 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of the Plasmodium falciparum triosephosphate isomerase-phosphoglycolate complex in two crystal forms: characterization of catalytic loop open and closed conformations in the ligand-bound state
Biochemistry, 41, 2002
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1LZO
 | | Plasmodium Falciparum Triosephosphate Isomerase-Phosphoglycolate Complex | | 分子名称: | 2-PHOSPHOGLYCOLIC ACID, Triosephosphate Isomerase | | 著者 | Parthasarathy, S, Balaram, H, Balaram, P, Murthy, M.R. | | 登録日 | 2002-06-11 | | 公開日 | 2003-01-28 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of the Plasmodium falciparum triosephosphate isomerase-phosphoglycolate complex in two crystal forms: characterization of catalytic loop open and closed conformations in the ligand-bound state
Biochemistry, 41, 2002
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5BNK
 | | Crystal structure of T75C mutant of Triosephosphate isomerase from Plasmodium falciparum | | 分子名称: | 1,2-ETHANEDIOL, SODIUM ION, Triosephosphate isomerase | | 著者 | Bandyopadhyay, D, Murthy, M.R.N, Balaram, H, Balaram, P. | | 登録日 | 2015-05-26 | | 公開日 | 2015-07-29 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Probing the role of highly conserved residues in triosephosphate isomerase - analysis of site specific mutants at positions 64 and 75 in the Plasmodial enzyme
Febs J., 282, 2015
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5BMX
 | | Crystal structure of T75N mutant of Triosephosphate isomerase from Plasmodium falciparum | | 分子名称: | 1,2-ETHANEDIOL, SODIUM ION, SULFATE ION, ... | | 著者 | Bandyopadhyay, D, Murthy, M.R.N, Balaram, H, Balaram, P. | | 登録日 | 2015-05-24 | | 公開日 | 2015-07-29 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Probing the role of highly conserved residues in triosephosphate isomerase - analysis of site specific mutants at positions 64 and 75 in the Plasmodial enzyme
Febs J., 282, 2015
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5BMW
 | | Crystal structure of T75V mutant of Triosephosphate isomerase from Plasmodium falciparum | | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Bandyopadhyay, D, Murthy, M.R.N, Balaram, H, Balaram, P. | | 登録日 | 2015-05-23 | | 公開日 | 2015-07-29 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Probing the role of highly conserved residues in triosephosphate isomerase - analysis of site specific mutants at positions 64 and 75 in the Plasmodial enzyme
Febs J., 282, 2015
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5BRB
 | | Crystal structure of Q64E mutant of Triosephosphate isomerase from Plasmodium falciparum | | 分子名称: | SODIUM ION, Triosephosphate isomerase | | 著者 | Bandyopadhyay, D, Murthy, M.R.N, Balaram, H, Balaram, P. | | 登録日 | 2015-05-30 | | 公開日 | 2015-07-29 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | | 主引用文献 | Probing the role of highly conserved residues in triosephosphate isomerase - analysis of site specific mutants at positions 64 and 75 in the Plasmodial enzyme
Febs J., 282, 2015
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1WOB
 | | Structure of a loop6 hinge mutant of Plasmodium falciparum Triosephosphate Isomerase, W168F, complexed to sulfate | | 分子名称: | SULFATE ION, Triosephosphate isomerase | | 著者 | Eaazhisai, K, Balaram, H, Balaram, P, Murthy, M.R.N. | | 登録日 | 2004-08-12 | | 公開日 | 2004-10-26 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structures of Unliganded and Inhibitor Complexes of W168F, a Loop6 Hinge Mutant of Plasmodium falciparum Triosephosphate Isomerase: Observation of an Intermediate Position of Loop6
J.Mol.Biol., 343, 2004
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1WOA
 | | Structure of the loop6 hinge mutant of Plasmodium falciparum Triosephosphate Isomerase, W168F, complexed with Glycerol-2-phosphate | | 分子名称: | 2-HYDROXY-1-(HYDROXYMETHYL)ETHYL DIHYDROGEN PHOSPHATE, Triosephosphate isomerase | | 著者 | Eaazhisai, K, Balaram, H, Balaram, P, Murthy, M.R.N. | | 登録日 | 2004-08-12 | | 公開日 | 2004-10-26 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structures of Unliganded and Inhibitor Complexes of W168F, a Loop6 Hinge Mutant of Plasmodium falciparum Triosephosphate Isomerase: Observation of an Intermediate Position of Loop6
J.Mol.Biol., 343, 2004
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1VGA
 | | Structures of unligated and inhibitor complexes of W168F mutant of Triosephosphate Isomerase from Plasmodium falciparum | | 分子名称: | Triosephosphate isomerase | | 著者 | Eaazhisai, K, Balaram, H, Balaram, P, Murthy, M.R.N. | | 登録日 | 2004-04-23 | | 公開日 | 2004-10-26 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structures of Unliganded and Inhibitor Complexes of W168F, a Loop6 Hinge Mutant of Plasmodium falciparum Triosephosphate Isomerase: Observation of an Intermediate Position of Loop6
J.Mol.Biol., 343, 2004
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1O5X
 | | Plasmodium falciparum TIM complexed to 2-phosphoglycerate | | 分子名称: | 2-PHOSPHOGLYCERIC ACID, 3-HYDROXYPYRUVIC ACID, PHOSPHITE ION, ... | | 著者 | Parthasarathy, S, Eaazhisai, K, Balaram, H, Balaram, P, Murthy, M.R. | | 登録日 | 2003-10-06 | | 公開日 | 2004-01-13 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Structure of Plasmodium falciparum Triose-phosphate Isomerase-2-Phosphoglycerate Complex at 1.1-A Resolution
J.Biol.Chem., 278, 2003
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4X22
 | | Crystal structure of Leptospira Interrogans Triosephosphate Isomerase (LiTIM) | | 分子名称: | 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, Triosephosphate isomerase | | 著者 | Pareek, V, Balaram, P, Murthy, M.R.N. | | 登録日 | 2014-11-25 | | 公開日 | 2016-02-10 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.084 Å) | | 主引用文献 | Connecting Active-Site Loop Conformations and Catalysis in Triosephosphate Isomerase: Insights from a Rare Variation at Residue 96 in the Plasmodial Enzyme
Chembiochem, 17, 2016
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2VFG
 | | Crystal structure of the F96H mutant of Plasmodium falciparum triosephosphate isomerase with 3-phosphoglycerate bound at the dimer interface | | 分子名称: | 3-PHOSPHOGLYCERIC ACID, TRIOSEPHOSPHATE ISOMERASE | | 著者 | Gayathri, P, Banerjee, M, Vijayalakshmi, A, Balaram, H, Balaram, P, Murthy, M.R.N. | | 登録日 | 2007-11-04 | | 公開日 | 2008-12-09 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Biochemical and Structural Characterization of Residue 96 Mutants of Plasmodium Falciparum Triosephosphate Isomerase: Active-Site Loop Conformation, Hydration and Identification of a Dimer-Interface Ligand-Binding Site.
Acta Crystallogr.,Sect.D, 65, 2009
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2VFD
 | | Crystal structure of the F96S mutant of Plasmodium falciparum triosephosphate isomerase | | 分子名称: | SULFATE ION, TRIOSEPHOSPHATE ISOMERASE | | 著者 | Gayathri, P, Banerjee, M, Vijayalakshmi, A, Balaram, H, Balaram, P, Murthy, M.R.N. | | 登録日 | 2007-11-03 | | 公開日 | 2008-12-09 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Biochemical and Structural Characterization of Residue 96 Mutants of Plasmodium Falciparum Triosephosphate Isomerase: Active-Site Loop Conformation, Hydration and Identification of a Dimer-Interface Ligand-Binding Site.
Acta Crystallogr.,Sect.D, 65, 2009
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2VFH
 | | Crystal structure of the F96W mutant of Plasmodium falciparum triosephosphate isomerase complexed with 3-phosphoglycerate | | 分子名称: | 3-PHOSPHOGLYCERIC ACID, TRIOSEPHOSPHATE ISOMERASE | | 著者 | Gayathri, P, Banerjee, M, Vijayalakshmi, A, Balaram, H, Balaram, P, Murthy, M.R.N. | | 登録日 | 2007-11-04 | | 公開日 | 2008-12-09 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Biochemical and Structural Characterization of Residue 96 Mutants of Plasmodium Falciparum Triosephosphate Isomerase: Active-Site Loop Conformation, Hydration and Identification of a Dimer-Interface Ligand-Binding Site.
Acta Crystallogr.,Sect.D, 65, 2009
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2VFF
 | | Crystal structure of the F96H mutant of Plasmodium falciparum triosephosphate isomerase | | 分子名称: | TRIOSEPHOSPHATE ISOMERASE | | 著者 | Gayathri, P, Banerjee, M, Vijayalakshmi, A, Balaram, H, Balaram, P, Murthy, M.R.N. | | 登録日 | 2007-11-04 | | 公開日 | 2008-12-09 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Biochemical and Structural Characterization of Residue 96 Mutants of Plasmodium Falciparum Triosephosphate Isomerase: Active-Site Loop Conformation, Hydration and Identification of a Dimer-Interface Ligand-Binding Site.
Acta Crystallogr.,Sect.D, 65, 2009
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2VFE
 | | Crystal structure of F96S mutant of Plasmodium falciparum triosephosphate isomerase with 3- phosphoglycerate bound at the dimer interface | | 分子名称: | 3-PHOSPHOGLYCERIC ACID, GLYCEROL, TRIOSEPHOSPHATE ISOMERASE | | 著者 | Gayathri, P, Banerjee, M, Vijayalakshmi, A, Balaram, H, Balaram, P, Murthy, M.R.N. | | 登録日 | 2007-11-03 | | 公開日 | 2008-12-09 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Biochemical and Structural Characterization of Residue 96 Mutants of Plasmodium Falciparum Triosephosphate Isomerase: Active-Site Loop Conformation, Hydration and Identification of a Dimer-Interface Ligand-Binding Site.
Acta Crystallogr.,Sect.D, 65, 2009
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2VFI
 | | Crystal structure of the Plasmodium falciparum triosephosphate isomerase in the loop closed state with 3-phosphoglycerate bound at the active site and interface | | 分子名称: | 3-PHOSPHOGLYCERIC ACID, TRIOSEPHOSPHATE ISOMERASE | | 著者 | Gayathri, P, Banerjee, M, Vijayalakshmi, A, Balaram, H, Balaram, P, Murthy, M.R.N. | | 登録日 | 2007-11-04 | | 公開日 | 2008-12-09 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Biochemical and Structural Characterization of Residue 96 Mutants of Plasmodium Falciparum Triosephosphate Isomerase: Active-Site Loop Conformation, Hydration and Identification of a Dimer-Interface Ligand-Binding Site.
Acta Crystallogr.,Sect.D, 65, 2009
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3PSW
 | | Structure of E97Q mutant of TIM from Plasmodium falciparum | | 分子名称: | 1,2-ETHANEDIOL, SULFATE ION, Triosephosphate isomerase | | 著者 | Samanta, M, Murthy, M.R.N, Balaram, H, Balaram, P. | | 登録日 | 2010-12-02 | | 公開日 | 2011-10-19 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Revisiting the mechanism of the triosephosphate isomerase reaction: the role of the fully conserved glutamic acid 97 residue
Chembiochem, 12, 2011
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3PVF
 | | Structure of C126S mutant of Plasmodium falciparum triosephosphate isomerase complexed with PGA | | 分子名称: | 2-PHOSPHOGLYCOLIC ACID, Triosephosphate isomerase | | 著者 | Samanta, M, Banerjee, M, Murthy, M.R.N, Balaram, H, Balaram, P. | | 登録日 | 2010-12-07 | | 公開日 | 2011-04-27 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Probing the role of the fully conserved Cys126 in triosephosphate isomerase by site-specific mutagenesis--distal effects on dimer stability.
Febs J., 278, 2011
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3PSV
 | | Structure of E97D mutant of TIM from Plasmodium falciparum | | 分子名称: | 1,2-ETHANEDIOL, SULFATE ION, Triosephosphate isomerase | | 著者 | Samanta, M, Murthy, M.R.N, Balaram, H, Balaram, P. | | 登録日 | 2010-12-02 | | 公開日 | 2011-10-19 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Revisiting the mechanism of the triosephosphate isomerase reaction: the role of the fully conserved glutamic acid 97 residue
Chembiochem, 12, 2011
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3PWA
 | | Structure of C126A mutant of Plasmodium falciparum triosephosphate isomerase | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, SULFATE ION, ... | | 著者 | Samanta, M, Banerjee, M, Murthy, M.R.N, Balaram, H, Balaram, P. | | 登録日 | 2010-12-08 | | 公開日 | 2011-04-27 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Probing the role of the fully conserved Cys126 in triosephosphate isomerase by site-specific mutagenesis--distal effects on dimer stability.
Febs J., 278, 2011
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3PY2
 | | Structure of C126S mutant of Plasmodium falciparum triosephosphate isomerase | | 分子名称: | 1,2-ETHANEDIOL, SULFATE ION, Triosephosphate isomerase | | 著者 | Samanta, M, Banerjee, M, Murthy, M.R.N, Balaram, H, Balaram, P. | | 登録日 | 2010-12-11 | | 公開日 | 2011-04-27 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Probing the role of the fully conserved Cys126 in triosephosphate isomerase by site-specific mutagenesis--distal effects on dimer stability.
Febs J., 278, 2011
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