4II9
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![BU of 4ii9 by Molmil](/molmil-images/mine/4ii9) | Crystal structure of Weissella viridescens FemXVv non-ribosomal amino acid transferase in complex with a peptidyl-RNA conjugate | 分子名称: | 5-mer peptide, FemX, GLYCEROL, ... | 著者 | Li de la Sierra-Gallay, I, Fonvielle, M, van Tilbeurgh, H, Arthur, M, Etheve-Quelquejeu, M. | 登録日 | 2012-12-20 | 公開日 | 2013-07-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | The Structure of FemXWv in Complex with a Peptidyl-RNA Conjugate: Mechanism of Aminoacyl Transfer from Ala-tRNA(Ala) to Peptidoglycan Precursors Angew.Chem.Int.Ed.Engl., 52, 2013
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3ZGP
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![BU of 3zgp by Molmil](/molmil-images/mine/3zgp) | NMR structure of the catalytic domain from E. faecium L,D- transpeptidase acylated by ertapenem | 分子名称: | (4R,5S)-3-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid, ERFK/YBIS/YCFS/YNHG | 著者 | Lecoq, L, Triboulet, S, Dubee, V, Bougault, C, Hugonnet, J.E, Arthur, M, Simorre, J.P. | 登録日 | 2012-12-18 | 公開日 | 2013-04-24 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | The Structure of Enterococcus Faecium L,D---Transpeptidase Acylated by Ertapenem Provides Insight Into the Inactivation Mechanism. Acs Chem.Biol., 8, 2013
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4YFM
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![BU of 4yfm by Molmil](/molmil-images/mine/4yfm) | Class A beta-lactamase from Mycobacterium abscessus | 分子名称: | ACETATE ION, Beta-lactamase, GLYCEROL | 著者 | Soroka, D, Li de la Sierra-Gallay, I, Dubee, V, van Tilbeurgh, H, Arthur, M. | 登録日 | 2015-02-25 | 公開日 | 2015-07-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Hydrolysis of Clavulanate by Mycobacterium tuberculosis beta-Lactamase BlaC Harboring a Canonical SDN Motif. Antimicrob.Agents Chemother., 59, 2015
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6FJ1
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![BU of 6fj1 by Molmil](/molmil-images/mine/6fj1) | Structure of the Ldtfm-avibactam carbamoyl enzyme | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, 3,6,9,12,15-PENTAOXAHEPTADECANE, CHLORIDE ION, ... | 著者 | Li de la Sierra Gallay, I, Iannazzo, L, Compain, F, Fonvielle, M, van Tilbeurgh, H, Edoo, Z, Arthur, M, Etheve-Quelquejeu, M, Hugonnet, J. | 登録日 | 2018-01-19 | 公開日 | 2019-01-30 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Synthesis of Avibactam Derivatives and Activity on beta-Lactamases and Peptidoglycan Biosynthesis Enzymes of Mycobacteria. Chemistry, 24, 2018
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2HKL
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![BU of 2hkl by Molmil](/molmil-images/mine/2hkl) | Crystal structure of Enterococcus faecium L,D-transpeptidase C442S mutant | 分子名称: | L,D-TRANSPEPTIDASE, SULFATE ION | 著者 | Delfosse, V, Hugonnet, J.-E, Magnet, S, Mainardi, J.-L, Arthur, M, Mayer, C. | 登録日 | 2006-07-05 | 公開日 | 2007-05-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of Enterococcus faecium L,D-transpeptidase C442S mutant To be Published
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1NE9
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![BU of 1ne9 by Molmil](/molmil-images/mine/1ne9) | Crystal Structure of Weissella viridescens FemX at 1.7 Ang Resolution | 分子名称: | FemX, MAGNESIUM ION | 著者 | Biarrotte-Sorin, S, Maillard, A.P, Delettre, J, Sougakoff, W, Arthur, M, Mayer, C. | 登録日 | 2002-12-11 | 公開日 | 2004-02-10 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structures of Weissella viridescens FemX and its complex with UDP-MurNAc-pentapeptide: insights into FemABX family substrates recognition. Structure, 12, 2004
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1P4N
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![BU of 1p4n by Molmil](/molmil-images/mine/1p4n) | Crystal Structure of Weissella viridescens FemX:UDP-MurNAc-pentapeptide complex | 分子名称: | FemX, GLYCEROL, MAGNESIUM ION, ... | 著者 | Biarrotte-Sorin, S, Maillard, A, Delettre, J, Sougakoff, W, Arthur, M, Mayer, C. | 登録日 | 2003-04-23 | 公開日 | 2004-02-10 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structures of Weissella viridescens FemX and its complex with UDP-MurNAc-pentapeptide: insights into FemABX family substrates recognition. Structure, 12, 2004
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1ZAT
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![BU of 1zat by Molmil](/molmil-images/mine/1zat) | Crystal Structure of an Enterococcus faecium peptidoglycan binding protein at 2.4 A resolution | 分子名称: | L,D-transpeptidase, SULFATE ION, ZINC ION | 著者 | Biarrotte-Sorin, S, Hugonnet, J.-E, Mainardi, J.-L, Gutmann, L, Rice, L, Arthur, M, Mayer, C. | 登録日 | 2005-04-07 | 公開日 | 2006-03-28 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal Structure of a Novel beta-Lactam-insensitive Peptidoglycan Transpeptidase. J.Mol.Biol., 359, 2006
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3GKR
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![BU of 3gkr by Molmil](/molmil-images/mine/3gkr) | Crystal Structure of Weissella viridescens FemX:UDP-MurNAc-hexapeptide complex | 分子名称: | ALANINE, FemX, GLYCEROL, ... | 著者 | Delfosse, V, Piton, J, Villet, R, Lecerf, M, Arthur, M, Mayer, C. | 登録日 | 2009-03-11 | 公開日 | 2010-03-23 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure of Weissella viridescens FemX with the UDP-MurNAc-hexapeptide product of the alanine transfer reaction To be Published
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1XE4
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![BU of 1xe4 by Molmil](/molmil-images/mine/1xe4) | Crystal Structure of Weissella viridescens FemX (K36M) Mutant | 分子名称: | FemX, MAGNESIUM ION | 著者 | Biarrotte-Sorin, S, Maillard, A.P, Arthur, M, Mayer, C. | 登録日 | 2004-09-09 | 公開日 | 2005-05-31 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structure-Based Site-Directed Mutagenesis of the UDP-MurNAc-Pentapeptide-Binding Cavity of the FemX Alanyl Transferase from Weissella viridescens J.Bacteriol., 187, 2005
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1XF8
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![BU of 1xf8 by Molmil](/molmil-images/mine/1xf8) | Crystal Structure of Weissella viridescens FemX (Y254F) Mutant | 分子名称: | FemX, MAGNESIUM ION | 著者 | Biarrotte-Sorin, S, Maillard, A.P, Arthur, M, Mayer, C. | 登録日 | 2004-09-14 | 公開日 | 2005-05-31 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure-Based Site-Directed Mutagenesis of the UDP-MurNAc-Pentapeptide-Binding Cavity of the FemX Alanyl Transferase from Weissella viridescens J.BACTERIOL., 187, 2005
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1XIX
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![BU of 1xix by Molmil](/molmil-images/mine/1xix) | |
3ZG4
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![BU of 3zg4 by Molmil](/molmil-images/mine/3zg4) | NMR structure of the catalytic domain from E. faecium L,D- transpeptidase | 分子名称: | ERFK/YBIS/YCFS/YNHG | 著者 | Lecoq, L, Dubee, V, Triboulet, S, Bougault, C, Hugonnet, J.E, Arthur, M, Simorre, J.P. | 登録日 | 2012-12-14 | 公開日 | 2013-04-24 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | The Structure of Enterococcus Faecium L,D---Transpeptidase Acylated by Ertapenem Provides Insight Into the Inactivation Mechanism. Acs Chem.Biol., 8, 2013
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3ZQD
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![BU of 3zqd by Molmil](/molmil-images/mine/3zqd) | B. subtilis L,D-transpeptidase | 分子名称: | L, D-TRANSPEPTIDASE YKUD | 著者 | Lecoq, L, Simorre, J.-P, Bougault, C, Arthur, M, Hugonnet, J.-E, Veckerle, C, Pessey, O. | 登録日 | 2011-06-09 | 公開日 | 2012-05-23 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Dynamics Induced by Beta-Lactam Antibiotics in the Active Site of Bacillus subtilis L,D-Transpeptidase. Structure, 20, 2012
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4A52
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![BU of 4a52 by Molmil](/molmil-images/mine/4a52) | NMR structure of the imipenem-acylated L,D-transpeptidase from Bacillus subtilis | 分子名称: | (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carboxylic acid, PUTATIVE L, D-TRANSPEPTIDASE YKUD | 著者 | Lecoq, L, Simorre, J, Bougault, C, Arthur, M, Hugonnet, J, Veckerle, C, Pessey, O. | 登録日 | 2011-10-24 | 公開日 | 2012-05-30 | 最終更新日 | 2018-01-24 | 実験手法 | SOLUTION NMR | 主引用文献 | Dynamics Induced by Beta-Lactam Antibiotics in the Active Site of Bacillus subtilis L,D-Transpeptidase. Structure, 20, 2012
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2MTZ
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![BU of 2mtz by Molmil](/molmil-images/mine/2mtz) | Haddock model of Bacillus subtilis L,D-transpeptidase in complex with a peptidoglycan hexamuropeptide | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-beta-muramic acid-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-beta-muramic acid-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-beta-muramic acid-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-beta-muramic acid-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-beta-muramic acid-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-beta-muramic acid, Putative L,D-transpeptidase YkuD, intact bacterial peptidoglycan | 著者 | Schanda, P, Triboulet, S, Laguri, C, Bougault, C, Ayala, I, Callon, M, Arthur, M, Simorre, J. | 登録日 | 2014-09-02 | 公開日 | 2015-01-14 | 最終更新日 | 2023-11-15 | 実験手法 | SOLID-STATE NMR | 主引用文献 | Atomic model of a cell-wall cross-linking enzyme in complex with an intact bacterial peptidoglycan. J.Am.Chem.Soc., 136, 2014
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6NTZ
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![BU of 6ntz by Molmil](/molmil-images/mine/6ntz) | Crystal structure of E. coli PBP5-meropenem | 分子名称: | (2S,3R,4S)-4-{[(3S,5R)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, D-alanyl-D-alanine carboxypeptidase | 著者 | Caveney, N.A, Strynadka, N.C.J, Caballero, G, Worrall, L.J. | 登録日 | 2019-01-30 | 公開日 | 2019-03-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural insight into YcbB-mediated beta-lactam resistance in Escherichia coli. Nat Commun, 10, 2019
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4G76
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![BU of 4g76 by Molmil](/molmil-images/mine/4g76) | |
6NTW
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![BU of 6ntw by Molmil](/molmil-images/mine/6ntw) | Crystal structure of E. coli YcbB | 分子名称: | (2S,3R,4S)-4-{[(3S,5R)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, Probable L,D-transpeptidase YcbB, SULFATE ION | 著者 | Caveney, N.A, Strynadka, N.C.J, Caballero, G, Worrall, L.J. | 登録日 | 2019-01-30 | 公開日 | 2019-03-20 | 最終更新日 | 2020-01-08 | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | 主引用文献 | Structural insight into YcbB-mediated beta-lactam resistance in Escherichia coli. Nat Commun, 10, 2019
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4G75
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![BU of 4g75 by Molmil](/molmil-images/mine/4g75) | Structure of PaeM, a colicin M-like bacteriocin produced by Pseudomonas aeruginosa | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, phosphodiesterase | 著者 | Touze, T, Graille, M, Mengin-Lecreulx, D. | 登録日 | 2012-07-20 | 公開日 | 2012-09-12 | 最終更新日 | 2012-11-14 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Functional and Structural Characterization of PaeM, a Colicin M-like Bacteriocin Produced by Pseudomonas aeruginosa. J.Biol.Chem., 287, 2012
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6DZ8
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![BU of 6dz8 by Molmil](/molmil-images/mine/6dz8) | |
8F3H
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![BU of 8f3h by Molmil](/molmil-images/mine/8f3h) | Crystal structure of Penicillin Binding Protein 5 (PBP5) S466 insertion variant apo form from Enterococcus faecium | 分子名称: | Penicillin binding protein 5, SULFATE ION | 著者 | D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W. | 登録日 | 2022-11-10 | 公開日 | 2023-07-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics Nat Commun, 2023
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8F3L
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![BU of 8f3l by Molmil](/molmil-images/mine/8f3l) | Crystal structure of Penicillin Binding Protein 5 (PBP5) T485A variant penicillin bound form from Enterococcus faecium | 分子名称: | OPEN FORM - PENICILLIN G, Penicillin binding protein 5, SULFATE ION | 著者 | D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W. | 登録日 | 2022-11-10 | 公開日 | 2023-07-05 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics Nat Commun, 2023
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8F3O
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![BU of 8f3o by Molmil](/molmil-images/mine/8f3o) | Crystal structure of Penicillin Binding Protein 5 (PBP5) R464A variant apo form from Enterococcus faecium | 分子名称: | Penicillin binding protein 5, SULFATE ION | 著者 | D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Peti, W, Page, R. | 登録日 | 2022-11-10 | 公開日 | 2023-07-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics Nat Commun, 2023
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8F3S
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![BU of 8f3s by Molmil](/molmil-images/mine/8f3s) | Crystal structure of Penicillin Binding Protein 5 (PBP5) T485M T499I variant penicillin bound form from Enterococcus faecium | 分子名称: | OPEN FORM - PENICILLIN G, Penicillin binding protein 5, SULFATE ION | 著者 | D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W. | 登録日 | 2022-11-10 | 公開日 | 2023-07-05 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics Nat Commun, 2023
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