4A52

NMR structure of the imipenem-acylated L,D-transpeptidase from Bacillus subtilis

Summary for 4A52

• Entry DOI: 10.2210/pdb4a52/pdb
• Related: 1Y7M 3ZQD 4A1I 4A1J 4A1K
• NMR Information: BMRB: 18037
• Descriptor: PUTATIVE L, D-TRANSPEPTIDASE YKUD, (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carboxylic acid (2 entities in total)
• Functional Keywords: transferase, peptidoglycan, antibiotic resistance, cysteine protease
• Biological source: BACILLUS SUBTILIS SUBSP. SUBTILIS STR. 168
• Cellular location: Spore wall : O34816
• Total number of polymer chains: 1
• Total formula weight: 19262.09

Authors

Lecoq, L.,Simorre, J.,Bougault, C.,Arthur, M.,Hugonnet, J.,Veckerle, C.,Pessey, O. (deposition date: 2011-10-24, release date: 2012-05-30, Last modification date: 2018-01-24)

• Primary citation: Lecoq, L.,Bougault, C.,Hugonnet, J.,Veckerle, C.,Pessey, O.,Arthur, M.,Simorre, J.P.; Dynamics Induced by Beta-Lactam Antibiotics in the Active Site of Bacillus subtilis L,D-Transpeptidase.; Structure, 20:850-861, 2012; PubMed: 22579252; DOI: 10.1016/J.STR.2012.03.015

Experimental method

SOLUTION NMR