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4AW3
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BU of 4aw3 by Molmil
Structure of the mixed-function P450 MycG F286V mutant in complex with mycinamicin V in P1 space group
分子名称: GLYCEROL, MYCINAMICIN V, P-450-LIKE PROTEIN, ...
著者Li, S, Tietz, D.R, Rutaganira, F.U, Kells, P.M, Anzai, Y, Kato, F, Pochapsky, T.C, Sherman, D.H, Podust, L.M.
登録日2012-05-30
公開日2012-09-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Substrate Recognition by the Multifunctional Cytochrome P450 Mycg in Mycinamicin Hydroxylation and Epoxidation Reactions.
J.Biol.Chem., 287, 2012
3ZSN
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BU of 3zsn by Molmil
Structure of the mixed-function P450 MycG F286A mutant in complex with mycinamicin IV
分子名称: BENZAMIDINE, GLYCEROL, MYCINAMICIN IV, ...
著者Li, S, Kells, P.M, Rutaganira, F.U, Anzai, Y, Kato, F, Sherman, D.H, Podust, L.M.
登録日2011-06-29
公開日2012-05-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Substrate Recognition by the Multifunctional Cytochrome P450 Mycg in Mycinamicin Hydroxylation and Epoxidation Reactions.
J.Biol.Chem., 287, 2012
2Y3S
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BU of 2y3s by Molmil
Structure of the tirandamycine-bound FAD-dependent tirandamycin oxidase TamL in C2 space group
分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
著者Carlson, J.C, Li, S, Gunatilleke, S.S, Anzai, Y, Burr, D.A, Podust, L.M, Sherman, D.H.
登録日2010-12-23
公開日2011-06-29
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Tirandamycin Biosynthesis is Mediated by Co-Dependent Oxidative Enzymes
Nat.Chem, 3, 2011
2Y08
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BU of 2y08 by Molmil
Structure of the substrate-free FAD-dependent tirandamycin oxidase TamL
分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
著者Carlson, J.C, Li, S, Gunatilleke, S.S, Anzai, Y, Burr, D.A, Podust, L.M, Sherman, D.H.
登録日2010-11-30
公開日2011-06-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Tirandamycin Biosynthesis is Mediated by Co-Dependent Oxidative Enzymes
Nat.Chem, 3, 2011
2Y3R
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BU of 2y3r by Molmil
Structure of the tirandamycin-bound FAD-dependent tirandamycin oxidase TamL in P21 space group
分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
著者Carlson, J.C, Li, S, Gunatilleke, S.S, Anzai, Y, Burr, D.A, Podust, L.M, Sherman, D.H.
登録日2010-12-22
公開日2011-06-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Tirandamycin Biosynthesis is Mediated by Co-Dependent Oxidative Enzymes
Nat.Chem, 3, 2011
2Y4G
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BU of 2y4g by Molmil
Structure of the Tirandamycin-bound FAD-dependent tirandamycin oxidase TamL in P212121 space group
分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
著者Carlson, J.C, Li, S, Gunatilleke, S.S, Anzai, Y, Burr, D.A, Podust, L.M, Sherman, D.H.
登録日2011-01-05
公開日2011-06-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Tirandamycin Biosynthesis is Mediated by Co-Dependent Oxidative Enzymes
Nat.Chem, 3, 2011
7A0S
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BU of 7a0s by Molmil
50S Deinococcus radiodurans ribosome bounded with mycinamicin I
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
著者Breiner, E, Eyal, Z, Matzov, D, Halfon, Y, Cimicata, G, Rozenberg, H, Zimmerman, E, Bashan, A, Yonath, A.
登録日2020-08-10
公開日2021-08-18
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献Ribosome-binding and anti-microbial studies of the mycinamicins, 16-membered macrolide antibiotics from Micromonospora griseorubida.
Nucleic Acids Res., 49, 2021
7A0R
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BU of 7a0r by Molmil
50S Deinococcus radiodurans ribosome bounded with mycinamicin I
分子名称: 50S ribosomal protein L13, 50S ribosomal protein L14, 50S ribosomal protein L15, ...
著者Breiner, E, Eyal, Z, Matzov, D, Halfon, Y, Cimicata, G, Rozenberg, H, Zimmerman, E, Bashan, A, Yonath, A.
登録日2020-08-10
公開日2021-08-18
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Ribosome-binding and anti-microbial studies of the mycinamicins, 16-membered macrolide antibiotics from Micromonospora griseorubida.
Nucleic Acids Res., 49, 2021
7A18
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BU of 7a18 by Molmil
50S Deinococcus radiodurans ribosome bounded with mycinamicin IV
分子名称: 50S ribosomal protein L13, 50S ribosomal protein L14, 50S ribosomal protein L15, ...
著者Breiner, E, Eyal, Z, Matzov, D, Halfon, Y, Cimicata, G, Rozenberg, H, Zimmerman, E, Bashan, A, Yonath, A.
登録日2020-08-12
公開日2021-10-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Ribosome-binding and anti-microbial studies of the mycinamicins, 16-membered macrolide antibiotics from Micromonospora griseorubida.
Nucleic Acids Res., 49, 2021
4X7U
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BU of 4x7u by Molmil
MycF mycinamicin III 3'-O-methyltransferase in complex with Mg, SAH and mycinamicin III (substrate)
分子名称: MAGNESIUM ION, MYCINAMICIN III, Mycinamicin III 3''-O-methyltransferase, ...
著者Bernard, S.M, Smith, J.L.
登録日2014-12-09
公開日2015-03-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural Basis of Substrate Specificity and Regiochemistry in the MycF/TylF Family of Sugar O-Methyltransferases.
Acs Chem.Biol., 10, 2015
4X81
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BU of 4x81 by Molmil
MycF mycinamicin III 3'-O-methyltransferase (E35Q, M56A, E139A variant) in complex with Mg, SAH and mycinamicin VI (MycE substrate)
分子名称: DIMETHYL SULFOXIDE, MAGNESIUM ION, Mycinamicin III 3''-O-methyltransferase, ...
著者Bernard, S.M, Smith, J.L.
登録日2014-12-09
公開日2015-03-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Structural Basis of Substrate Specificity and Regiochemistry in the MycF/TylF Family of Sugar O-Methyltransferases.
Acs Chem.Biol., 10, 2015
4X7W
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BU of 4x7w by Molmil
MycF mycinamicin III 3'-O-methyltransferase (E35Q, E139A variant) in complex with Mg, SAH and mycinamicin VI (MycE substrate)
分子名称: MAGNESIUM ION, Mycinamicin III 3''-O-methyltransferase, Mycinamicin VI, ...
著者Bernard, S.M, Smith, J.L.
登録日2014-12-09
公開日2015-03-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural Basis of Substrate Specificity and Regiochemistry in the MycF/TylF Family of Sugar O-Methyltransferases.
Acs Chem.Biol., 10, 2015
4X7Z
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BU of 4x7z by Molmil
MycF mycinamicin III 3'-O-methyltransferase (E35Q, M56A, E139A variant) in complex with Mg, SAH and mycinamicin III (substrate)
分子名称: DIMETHYL SULFOXIDE, MAGNESIUM ION, MYCINAMICIN III, ...
著者Bernard, S.M, Smith, J.L.
登録日2014-12-09
公開日2015-03-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Structural Basis of Substrate Specificity and Regiochemistry in the MycF/TylF Family of Sugar O-Methyltransferases.
Acs Chem.Biol., 10, 2015
2Y98
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BU of 2y98 by Molmil
Structure of the mixed-function P450 MycG in complex with mycinamicin IV in P21212 space group
分子名称: CHLORIDE ION, GLYCEROL, MYCINAMICIN IV, ...
著者Li, S, Kells, P.M, Sherman, D.H, Podust, L.M.
登録日2011-02-12
公開日2012-02-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Substrate Recognition by the Multifunctional Cytochrome P450 Mycg in Mycinamicin Hydroxylation and Epoxidation Reactions.
J.Biol.Chem., 287, 2012
2YCA
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BU of 2yca by Molmil
Mixed-function P450 MycG in complex with mycinamicin III in P21212 space group
分子名称: GLYCEROL, MYCINAMICIN III, P-450-LIKE PROTEIN, ...
著者Li, S, Kells, P.M, Sherman, D.H, Podust, L.M.
登録日2011-03-12
公開日2012-03-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Substrate Recognition by the Multifunctional Cytochrome P450 Mycg in Mycinamicin Hydroxylation and Epoxidation Reactions.
J.Biol.Chem., 287, 2012
3SSO
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BU of 3sso by Molmil
MycE Methyltransferase from the Mycinamycin Biosynthetic Pathway in Complex with Mg and SAH, Crystal form 2
分子名称: MAGNESIUM ION, Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
著者Akey, D.L, Smith, J.L.
登録日2011-07-08
公開日2011-08-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.895 Å)
主引用文献A new structural form in the SAM/metal-dependent o‑methyltransferase family: MycE from the mycinamicin biosynthetic pathway.
J.Mol.Biol., 413, 2011
3SSN
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BU of 3ssn by Molmil
MycE Methyltransferase from the Mycinamycin Biosynthetic Pathway in Complex with Mg, SAH, and Mycinamycin VI
分子名称: DIMETHYL SULFOXIDE, GLYCEROL, MAGNESIUM ION, ...
著者Akey, D.L, Smith, J.L.
登録日2011-07-08
公開日2011-08-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.392 Å)
主引用文献A new structural form in the SAM/metal-dependent o‑methyltransferase family: MycE from the mycinamicin biosynthetic pathway.
J.Mol.Biol., 413, 2011
3SSM
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BU of 3ssm by Molmil
MycE Methyltransferase from the Mycinamycin Biosynthetic Pathway in Complex with Mg and SAH, Crystal form 1
分子名称: MAGNESIUM ION, Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
著者Akey, D.L, Smith, J.L.
登録日2011-07-08
公開日2011-08-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.247 Å)
主引用文献A new structural form in the SAM/metal-dependent o‑methyltransferase family: MycE from the mycinamicin biosynthetic pathway.
J.Mol.Biol., 413, 2011
2Y5Z
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BU of 2y5z by Molmil
Mixed-function P450 MycG in complex with mycinamicin III in C2221 space group
分子名称: BENZAMIDINE, GLYCEROL, MYCINAMICIN III, ...
著者Li, S, Kells, P.M, Sherman, D.H, Podust, L.M.
登録日2011-01-19
公開日2012-02-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Substrate Recognition by the Multifunctional Cytochrome P450 Mycg in Mycinamicin Hydroxylation and Epoxidation Reactions.
J.Biol.Chem., 287, 2012
2Y46
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BU of 2y46 by Molmil
Structure of the mixed-function P450 MycG in complex with mycinamicin IV in C 2 2 21 space group
分子名称: BENZAMIDINE, GLYCEROL, MYCINAMICIN IV, ...
著者Li, S, Kells, P.M, Sherman, D.H, Podust, L.M.
登録日2011-01-05
公開日2012-01-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Substrate Recognition by the Multifunctional Cytochrome P450 Mycg in Mycinamicin Hydroxylation and Epoxidation Reactions.
J.Biol.Chem., 287, 2012
2Y5N
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BU of 2y5n by Molmil
Structure of the mixed-function P450 MycG in complex with mycinamicin V in P21 space group
分子名称: GLYCEROL, MAGNESIUM ION, MYCINAMICIN V, ...
著者Li, S, Kells, P.M, Sherman, D.H, Podust, L.M.
登録日2011-01-15
公開日2012-02-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Substrate Recognition by the Multifunctional Cytochrome P450 Mycg in Mycinamicin Hydroxylation and Epoxidation Reactions.
J.Biol.Chem., 287, 2012
2YGX
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BU of 2ygx by Molmil
Structure of the mixed-function P450 MycG in P21 space group
分子名称: GLYCEROL, P-450-LIKE PROTEIN, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Li, S, Kells, P.M, Rutaganira, F.U, Sherman, D.H, Podust, L.M.
登録日2011-04-22
公開日2012-02-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Substrate Recognition by the Multifunctional Cytochrome P450 Mycg in Mycinamicin Hydroxylation and Epoxidation Reactions.
J.Biol.Chem., 287, 2012
5UHU
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BU of 5uhu by Molmil
Solution conformation of cytochrome P450 MycG with mycinamicin IV bound
分子名称: MYCINAMICIN IV, Mycinamicin IV hydroxylase/epoxidase, PROTOPORPHYRIN IX CONTAINING FE
著者Pochapsky, T.C, Tietz, D.R.
登録日2017-01-12
公開日2017-08-23
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution Conformations and Dynamics of Substrate-Bound Cytochrome P450 MycG.
Biochemistry, 56, 2017
4X7V
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BU of 4x7v by Molmil
MycF mycinamicin III 3'-O-methyltransferase (E35Q, E139A variant) in complex with Mg, SAH and mycinamicin IV (product)
分子名称: MAGNESIUM ION, MYCINAMICIN IV, Mycinamicin III 3''-O-methyltransferase, ...
著者Bernard, S.M, Smith, J.L.
登録日2014-12-09
公開日2015-03-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural Basis of Substrate Specificity and Regiochemistry in the MycF/TylF Family of Sugar O-Methyltransferases.
Acs Chem.Biol., 10, 2015
4XVZ
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BU of 4xvz by Molmil
MycF mycinamicin III 3'-O-methyltransferase in complex with Mg
分子名称: CHLORIDE ION, MAGNESIUM ION, Mycinamicin III 3''-O-methyltransferase
著者Akey, D.L, Smith, J.L.
登録日2015-01-28
公開日2015-03-04
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Structural Basis of Substrate Specificity and Regiochemistry in the MycF/TylF Family of Sugar O-Methyltransferases.
Acs Chem.Biol., 10, 2015

 

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