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8ZKC
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BU of 8zkc by Molmil
iron-sulfur cluster transfer protein ApbC
分子名称: GLYCEROL, Iron-sulfur cluster carrier protein, MAGNESIUM ION
著者Yang, J, Liu, L.
登録日2024-05-16
公開日2024-06-12
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystal structure of the iron-sulfur cluster transfer protein ApbC from Escherichia coli.
Biochem.Biophys.Res.Commun., 722, 2024
6D6V
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BU of 6d6v by Molmil
CryoEM structure of Tetrahymena telomerase with telomeric DNA at 4.8 Angstrom resolution
分子名称: DNA (5'-D(P*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*G)-3'), RNA (159-MER), Telomerase associated protein p65, ...
著者Jiang, J, Wang, Y, Susac, L, Chan, H, Basu, R, Zhou, Z.H, Feigon, J.
登録日2018-04-22
公開日2018-05-30
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Structure of Telomerase with Telomeric DNA.
Cell, 173, 2018
4V43
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BU of 4v43 by Molmil
Structural and mechanistic basis for allostery in the bacterial chaperonin GroEL
分子名称: GROEL PROTEIN
著者Wang, J.
登録日2002-01-02
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.52 Å)
主引用文献A GroEL/GroES complex structure revisited: the structure-based mechanism of ATP hydrolysis
To be Published
7XR5
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BU of 7xr5 by Molmil
Crystal structure of imine reductase with NAPDH from Streptomyces albidoflavus
分子名称: 3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57-nonadecaoxanonapentacontane-1,59-diol, 6-phosphogluconate dehydrogenase NAD-binding, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Zhang, J, Chen, R.C, Gao, S.S.
登録日2022-05-09
公開日2022-10-19
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Actinomycetes-derived imine reductases with a preference towards bulky amine substrates.
Commun Chem, 5, 2022
1MNF
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BU of 1mnf by Molmil
Domain motions in GroEL upon binding of an oligopeptide
分子名称: 12-residue peptide substrate, groEL protein
著者Wang, J, Chen, L.
登録日2002-09-05
公開日2003-10-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Domain Motions in GroEL upon Binding of an Oligopeptide.
J.Mol.Biol., 334, 2003
1MP6
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BU of 1mp6 by Molmil
Structure of the transmembrane region of the M2 protein H+ channel by solid state NMR spectroscopy
分子名称: Matrix protein M2
著者Wang, J, Kim, S, Kovacs, F, Cross, T.A.
登録日2002-09-11
公開日2002-09-25
最終更新日2024-05-22
実験手法SOLID-STATE NMR
主引用文献Structure of the transmembrane region of the M2 protein H(+) channel.
Protein Sci., 10, 2001
5D6Q
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BU of 5d6q by Molmil
Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a ligand
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1-ethyl-3-{4-[(E)-2-(pyridin-3-yl)ethenyl]-5-(1H-pyrrol-2-yl)-1,3-thiazol-2-yl}urea, DNA gyrase subunit B, ...
著者Zhang, J, Yang, Q, Cross, J.B, Romero, J.A.C, Ryan, M.D, Lippa, B, Dolle, R.E, Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C.
登録日2015-08-12
公開日2015-11-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Discovery of Azaindole Ureas as a Novel Class of Bacterial Gyrase B Inhibitors.
J.Med.Chem., 58, 2015
5D7D
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BU of 5d7d by Molmil
Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a ligand
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 7-propyl-3-[2-(pyridin-3-yl)-1,3-thiazol-5-yl]-1,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one, CHLORIDE ION, ...
著者Zhang, J, Yang, Q, Cross, J.B, Romero, J.A.C, Ryan, M.D, Lippa, B, Dolle, R.E, Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C.
登録日2015-08-13
公開日2015-11-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Discovery of Indazole Derivatives as a Novel Class of Bacterial Gyrase B Inhibitors.
Acs Med.Chem.Lett., 6, 2015
5D7C
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BU of 5d7c by Molmil
Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a ligand
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1-ethyl-3-[1-(pyridin-2-yl)-6-(pyridin-3-yl)-1H-pyrrolo[3,2-b]pyridin-3-yl]urea, DNA gyrase subunit B, ...
著者Zhang, J, Yang, Q, Cross, J.B, Romero, J.A.C, Ryan, M.D, Lippa, B, Dolle, R.E, Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C.
登録日2015-08-13
公開日2015-11-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Discovery of Azaindole Ureas as a Novel Class of Bacterial Gyrase B Inhibitors.
J.Med.Chem., 58, 2015
5D7R
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BU of 5d7r by Molmil
Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a ligand
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 3-hydroxy-5-[5-(6-hydroxy-7-propyl-2H-indazol-3-yl)-1,3-thiazol-2-yl]pyridine-2-carboxylic acid, CHLORIDE ION, ...
著者Zhang, J, Yang, Q, Cross, J.B, Romero, J.A.C, Ryan, M.D, Lippa, B, Dolle, R.E, Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C.
登録日2015-08-14
公開日2015-11-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Discovery of Indazole Derivatives as a Novel Class of Bacterial Gyrase B Inhibitors.
Acs Med.Chem.Lett., 6, 2015
4OH4
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BU of 4oh4 by Molmil
Crystal structure of BRI1 in complex with BKI1
分子名称: BRI1 kinase inhibitor 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Protein BRASSINOSTEROID INSENSITIVE 1
著者Wang, J, Wang, J, Wu, J.W, Wang, Z.X.
登録日2014-01-17
公開日2014-10-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural insights into the negative regulation of BRI1 signaling by BRI1-interacting protein BKI1.
Cell Res., 24, 2014
5DQU
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BU of 5dqu by Molmil
Crystal Structure of Cas-DNA-10 complex
分子名称: CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (5'-D(*GP*AP*GP*TP*CP*GP*AP*TP*GP*CP*TP*TP*TP*TP*T)-3'), ...
著者Wang, J, Li, J, Zhao, H, Sheng, G, Wang, M, Yin, M, Wang, Y.
登録日2015-09-15
公開日2015-11-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献Structural and Mechanistic Basis of PAM-Dependent Spacer Acquisition in CRISPR-Cas Systems.
Cell, 163, 2015
3UIT
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BU of 3uit by Molmil
Overall structure of Patj/Pals1/Mals complex
分子名称: ACETATE ION, InaD-like protein, MAGUK p55 subfamily member 5, ...
著者Zhang, J, Yang, X, Long, J, Shen, Y.
登録日2011-11-06
公開日2012-02-22
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure of an L27 domain heterotrimer from cell polarity complex Patj/Pals1/Mals2 reveals mutually independent L27 domain assembly mode
J.Biol.Chem., 287, 2012
4O26
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BU of 4o26 by Molmil
Crystal structure of the TRBD domain of TERT and the CR4/5 of TR
分子名称: SULFATE ION, Telomerase TR, Telomerase reverse transcriptase
著者Huang, J, Wu, J, Lei, M.
登録日2013-12-16
公開日2014-05-07
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (3.001 Å)
主引用文献Structural basis for protein-RNA recognition in telomerase.
Nat.Struct.Mol.Biol., 21, 2014
6DH9
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BU of 6dh9 by Molmil
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with MSDC-0602
分子名称: (5S)-5-({4-[2-(3-methoxyphenyl)-2-oxoethoxy]phenyl}methyl)-1,3-thiazolidine-2,4-dione, Peroxisome proliferator-activated receptor gamma, nonanoic acid
著者Shang, J, Kojetin, D.J.
登録日2018-05-18
公開日2019-05-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with MSDC-0602
To Be Published
6DGO
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BU of 6dgo by Molmil
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Troglitazone
分子名称: (5S)-5-[(4-{[(2R)-6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-1-benzopyran-2-yl]methoxy}phenyl)methyl]-1,3-thiazolidine-2,4-dione, Peroxisome proliferator-activated receptor gamma
著者Shang, J, Kojetin, D.J.
登録日2018-05-17
公開日2019-05-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Quantitative structural assessment of graded receptor agonism.
Proc.Natl.Acad.Sci.USA, 116, 2019
4FAP
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BU of 4fap by Molmil
ATOMIC STRUCTURES OF THE RAPAMYCIN ANALOGS IN COMPLEX WITH BOTH HUMAN FKBP12 AND FRB DOMAIN OF FRAP
分子名称: C15-(R)-METHYLTHIENYL RAPAMYCIN, FK506-BINDING PROTEIN, FKBP12-RAPAMYCIN ASSOCIATED PROTEIN
著者Liang, J, Clardy, J.
登録日1999-05-06
公開日2000-09-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Refined structure of the FKBP12-rapamycin-FRB ternary complex at 2.2 A resolution.
Acta Crystallogr.,Sect.D, 55, 1999
7XZ9
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BU of 7xz9 by Molmil
Mutant (E236A) of the N-terminal domain of fucoidan lyase FdlA
分子名称: Fucoidan lyase
著者Wang, J, Li, M, Pan, W.
登録日2022-06-02
公開日2022-09-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Structural and Biochemical Analysis Reveals Catalytic Mechanism of Fucoidan Lyase from Flavobacterium sp. SA-0082.
Mar Drugs, 20, 2022
7XZD
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BU of 7xzd by Molmil
Mutant (F179A) of the N-terminal domain of fucoidan lyase FdlA
分子名称: Fucoidan lyase, IMIDAZOLE
著者Wang, J, Li, M, Pan, X.
登録日2022-06-02
公開日2022-09-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural and Biochemical Analysis Reveals Catalytic Mechanism of Fucoidan Lyase from Flavobacterium sp. SA-0082.
Mar Drugs, 20, 2022
7XZF
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BU of 7xzf by Molmil
Wild type of the N-terminal domain of fucoidan lyase FdlA
分子名称: Fucoidan lyase, GLYCEROL, IMIDAZOLE, ...
著者Wang, J, Li, M, Pan, X.
登録日2022-06-02
公開日2022-09-28
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structural and Biochemical Analysis Reveals Catalytic Mechanism of Fucoidan Lyase from Flavobacterium sp. SA-0082.
Mar Drugs, 20, 2022
7XZ8
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BU of 7xz8 by Molmil
Mutant (K141A) of the N-terminal domain of fucoidan lyase FdlA
分子名称: Fucoidan lyase
著者Wang, J, Li, M, Pan, X.
登録日2022-06-02
公開日2022-09-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Structural and Biochemical Analysis Reveals Catalytic Mechanism of Fucoidan Lyase from Flavobacterium sp. SA-0082.
Mar Drugs, 20, 2022
7XZB
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BU of 7xzb by Molmil
Mutant (Y242A) of the N-terminal domain of fucoidan lyase FdlA
分子名称: Fucoidan lyase, SULFATE ION
著者Wang, J, Li, M, Pan, X.
登録日2022-06-02
公開日2022-09-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural and Biochemical Analysis Reveals Catalytic Mechanism of Fucoidan Lyase from Flavobacterium sp. SA-0082.
Mar Drugs, 20, 2022
7XZA
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BU of 7xza by Molmil
Mutant (Y242F) of the N-terminal domain of fucoidan lyase FdlA
分子名称: Fucoidan lyase FdlA
著者Wang, J, Li, M, Pan, X.
登録日2022-06-02
公開日2022-09-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Structural and Biochemical Analysis Reveals Catalytic Mechanism of Fucoidan Lyase from Flavobacterium sp. SA-0082.
Mar Drugs, 20, 2022
7XZE
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BU of 7xze by Molmil
Mutant (H176A) of the N-terminal domain of fucoidan lyase FdlA
分子名称: Fucoidan lyase, IMIDAZOLE, SULFATE ION
著者Wang, J, Li, M, Pan, X.
登録日2022-06-02
公開日2022-09-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and Biochemical Analysis Reveals Catalytic Mechanism of Fucoidan Lyase from Flavobacterium sp. SA-0082.
Mar Drugs, 20, 2022
7XZ7
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BU of 7xz7 by Molmil
Mutant (D137A) of the N-terminal domain of fucoidan lyase FdlA
分子名称: Fucoidan lyase
著者Wang, J, Li, M, Pan, X.
登録日2022-06-02
公開日2022-09-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structural and Biochemical Analysis Reveals Catalytic Mechanism of Fucoidan Lyase from Flavobacterium sp. SA-0082.
Mar Drugs, 20, 2022

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