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3RIQ
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BU of 3riq by Molmil
Siphovirus 9NA tailspike receptor binding domain
分子名称: GLYCEROL, Tailspike protein
著者Andres, D, Roske, Y, Doering, C, Heinemann, U, Seckler, R, Barbirz, S.
登録日2011-04-14
公開日2012-02-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Tail morphology controls DNA release in two Salmonella phages with one lipopolysaccharide receptor recognition system.
Mol.Microbiol., 83, 2012
3TH0
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BU of 3th0 by Molmil
P22 Tailspike complexed with S.Paratyphi O antigen octasaccharide
分子名称: Bifunctional tail protein, GLYCEROL, alpha-D-galactopyranose-(1-2)-[alpha-D-Paratopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-alpha-L-rhamnopyranose-(1-3)-alpha-D-galactopyranose-(1-2)-[alpha-D-Paratopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-alpha-L-rhamnopyranose
著者Andres, D, Gohlke, U, Heinemann, U, Seckler, R, Barbirz, S.
登録日2011-08-18
公開日2012-08-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献An essential serotype recognition pocket on phage P22 tailspike protein forces Salmonella enterica serovar Paratyphi A O-antigen fragments to bind as nonsolution conformers.
Glycobiology, 23, 2013
5IEX
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BU of 5iex by Molmil
Crystal structure of (R,S)-S-{4-[(5-Bromo-4-{[(2R,3R)-2-hydroxy-1-methylpropyl]oxy}- pyrimidin-2-yl)amino]phenyl}-S-cyclopropylsulfoximide bound to CDK2
分子名称: (2R,3R)-3-[(5-bromo-2-{[4-(S-cyclopropylsulfonimidoyl)phenyl]amino}pyrimidin-4-yl)oxy]butan-2-ol, Cyclin-dependent kinase 2
著者Ayaz, P, Andres, D, Kwiatkowski, D.A, Kolbe, C, Lienau, P, Siemeister, G, Luecking, U, Stegmann, C.M.
登録日2016-02-25
公開日2016-04-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Conformational Adaption May Explain the Slow Dissociation Kinetics of Roniciclib (BAY 1000394), a Type I CDK Inhibitor with Kinetic Selectivity for CDK2 and CDK9.
Acs Chem.Biol., 11, 2016
5IEV
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BU of 5iev by Molmil
Crystal structure of BAY 1000394 (Roniciclib) bound to CDK2
分子名称: Cyclin-dependent kinase 2, Roniciclib
著者Ayaz, P, Andres, D, Kwiatkowski, D.A, Kolbe, C, Lienau, P, Siemeister, G, Luecking, U, Stegmann, C.M.
登録日2016-02-25
公開日2016-04-27
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Conformational Adaption May Explain the Slow Dissociation Kinetics of Roniciclib (BAY 1000394), a Type I CDK Inhibitor with Kinetic Selectivity for CDK2 and CDK9.
Acs Chem.Biol., 11, 2016
5IF1
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BU of 5if1 by Molmil
Crystal structure apo CDK2/cyclin A
分子名称: Cyclin-A2, Cyclin-dependent kinase 2
著者Ayaz, P, Andres, D, Kwiatkowski, D.A, Kolbe, C, Lienau, P, Siemeister, G, Luecking, U, Stegmann, C.M.
登録日2016-02-25
公開日2016-04-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Conformational Adaption May Explain the Slow Dissociation Kinetics of Roniciclib (BAY 1000394), a Type I CDK Inhibitor with Kinetic Selectivity for CDK2 and CDK9.
Acs Chem.Biol., 11, 2016
5IEY
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BU of 5iey by Molmil
Crystal structure of a CDK inhibitor bound to CDK2
分子名称: 4-[(4-{[(2R,3R)-3-hydroxybutan-2-yl]amino}pyrimidin-2-yl)amino]benzene-1-sulfonamide, Cyclin-dependent kinase 2
著者Ayaz, P, Andres, D, Kwiatkowski, D.A, Kolbe, C, Lienau, P, Siemeister, G, Luecking, U, Stegmann, C.M.
登録日2016-02-25
公開日2016-04-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Conformational Adaption May Explain the Slow Dissociation Kinetics of Roniciclib (BAY 1000394), a Type I CDK Inhibitor with Kinetic Selectivity for CDK2 and CDK9.
Acs Chem.Biol., 11, 2016
2VNL
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BU of 2vnl by Molmil
MUTANT Y108Wdel OF THE HEADBINDING DOMAIN OF PHAGE P22 TAILSPIKE C- TERMINally fused to ISOLEUCINE ZIPPER pIIGCN4 (chimera II)
分子名称: BIFUNCTIONAL TAIL PROTEIN, PIIGCN4, GLYCEROL
著者Mueller, J.J, Seul, A, Mueller, G, Seckler, R, Heinemann, U.
登録日2008-02-05
公開日2009-02-10
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Bacteriophage P22 Tailspike: Structure of the Complete Protein and Function of the Interdomain Linker
Acta Crystallogr.,Sect.D, 70, 2014
2XC1
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BU of 2xc1 by Molmil
Full-length Tailspike Protein Mutant Y108W of Bacteriophage P22
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, BIFUNCTIONAL TAIL PROTEIN, CALCIUM ION, ...
著者Mueller, J.J, Seul, A, Seckler, R, Heinemann, U.
登録日2010-04-15
公開日2011-05-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Bacteriophage P22 Tailspike: Structure of the Complete Protein and Function of the Interdomain Linker
Acta Crystallogr.,Sect.D, 70, 2014
2VKY
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BU of 2vky by Molmil
Headbinding Domain of Phage P22 Tailspike C-Terminally Fused to Isoleucine Zipper pIIGCN4 (Chimera I)
分子名称: TAIL PROTEIN, PIIGCN4
著者Seul, A, Mueller, J.J, Mueller, G, Heinemann, U, Seckler, R.
登録日2008-01-04
公開日2009-02-10
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Bacteriophage P22 Tailspike: Structure of the Complete Protein and Function of the Interdomain Linker
Acta Crystallogr.,Sect.D, 70, 2014
6F7K
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BU of 6f7k by Molmil
Crystal structure of Dettilon tailspike protein (gp208)
分子名称: 1,2-ETHANEDIOL, Tailspike, alpha-D-galactopyranose-(1-6)-beta-D-mannopyranose-(1-4)-alpha-L-rhamnopyranose-(1-3)-alpha-D-galactopyranose, ...
著者Roske, Y, Heinemann, U.
登録日2017-12-11
公開日2018-12-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Time-resolved DNA release from an O-antigen-specificSalmonellabacteriophage with a contractile tail.
J.Biol.Chem., 294, 2019
6F7D
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BU of 6f7d by Molmil
Crystal structure of Dettilon tailspike protein (gp208)
分子名称: 1,2-ETHANEDIOL, Tailspike
著者Roske, Y, Heinemann, U.
登録日2017-12-08
公開日2018-12-19
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.634 Å)
主引用文献Time-resolved DNA release from an O-antigen-specificSalmonellabacteriophage with a contractile tail.
J.Biol.Chem., 294, 2019
4NHR
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BU of 4nhr by Molmil
Crystal structure of the outer membrane lipopolysaccharide transport protein LptE (RlpB)
分子名称: DI(HYDROXYETHYL)ETHER, LPS-assembly lipoprotein LptE
著者Malojcic, G, Kahne, D.
登録日2013-11-05
公開日2014-07-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献LptE binds to and alters the physical state of LPS to catalyze its assembly at the cell surface.
Proc.Natl.Acad.Sci.USA, 111, 2014

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件を2024-11-06に公開中

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