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1TTK
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NMR solution structure of omega-conotoxin MVIIA, a N-type calcium channel blocker
分子名称: Omega-conotoxin MVIIa
著者Adams, D.J, Smith, A.B, Schroeder, C.I, Yasuda, T, Lewis, R.J.
登録日2004-06-22
公開日2004-07-06
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献omega-conotoxin CVID inhibits a pharmacologically distinct voltage-sensitive calcium channel associated with transmitter release from preganglionic nerve terminals
J.Biol.Chem., 278, 2003
1TT3
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NMR soulution structure of omega-conotoxin [K10]MVIIA
分子名称: Omega-conotoxin MVIIa
著者Adams, D.J, Smith, A.B, Schroeder, C.I, Yasuda, T, Lewis, R.J.
登録日2004-06-21
公開日2004-07-06
最終更新日2021-11-10
実験手法SOLUTION NMR
主引用文献omega-conotoxin CVID inhibits a pharmacologically distinct voltage-sensitive calcium channel associated with transmitter release from preganglionic nerve terminals
J.Biol.Chem., 278, 2003
1MXP
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BU of 1mxp by Molmil
Solution structure of the ribbon disulfide bond isomer of alpha-conotoxin AuIB
分子名称: alpha-conotoxin AuIB
著者Dutton, J.L, Bansal, P.S, Hogg, R.C, Adams, D.J, Alewood, P.F, Craik, D.J.
登録日2002-10-03
公開日2002-12-30
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献A New Level of Conotoxin Diversity, a Non-native Disulfide Bond Connectivity in alpha -Conotoxin AuIB Reduces Structural Definition but Increases Biological Activity.
J.Biol.Chem., 277, 2002
1MTQ
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THREE-DIMENSIONAL SOLUTION STRUCTURE OF ALPHA-CONOTOXIN GID BY NMR SPECTROSCOPY
分子名称: alpha-conotoxin GID
著者Nicke, A, Loughnan, M.L, Millard, E.L, Alewood, P.F, Adams, D.J, Daly, N.L, Craik, D.J, Lewis, R.J.
登録日2002-09-22
公開日2003-02-11
最終更新日2020-06-24
実験手法SOLUTION NMR
主引用文献Isolation, Structure, and Activity of GID, a Novel alpha 4/7-Conotoxin with an Extended N-terminal Sequence
J.BIOL.CHEM., 278, 2003
1MXN
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BU of 1mxn by Molmil
Solution structure of alpha-conotoxin AuIB
分子名称: alpha-conotoxin AuIB
著者Dutton, J.L, Bansal, P.S, Hogg, R.C, Adams, D.J, Alewood, P.F, Craik, D.J.
登録日2002-10-02
公開日2002-12-30
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献A New Level of Conotoxin Diversity, a Non-native Disulfide Bond Connectivity in alpha -Conotoxin AuIB Reduces Structural Definition but Increases Biological Activity.
J.Biol.Chem., 277, 2002
1W9V
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BU of 1w9v by Molmil
Specificity and affinity of natural product cyclopentapeptide argifin against Aspergillus fumigatus
分子名称: ARGIFIN, CHITINASE, SULFATE ION
著者Rao, F.V, Houston, D.R, Boot, R.G, Aerts, J.M.F.G, Hodkinson, M, Adams, D.J, Shiomi, K, Omura, S, van Aalten, D.M.F.
登録日2004-10-19
公開日2005-01-10
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Specificity and Affinity of Natural Product Cyclopentapeptide Inhibitors Against Aspergillus Fumigatus, Human and Bacterial Chitinases
Chem.Biol., 12, 2005
1W9U
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Specificity and affnity of natural product cyclopentapeptide inhibitor Argadin against Aspergillus fumigatus chitinase
分子名称: ARGADIN, CHITINASE, SULFATE ION
著者Rao, F.V, Houston, D.R, Boot, R.G, Aerts, J.M.F.G, Hodkinson, M, Adams, D.J, Shiomi, K, Omura, S, van Aalten, D.M.F.
登録日2004-10-19
公開日2004-11-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Specificity and Affinity of Natural Product Cyclopentapeptide Inhibitors Against Aspergillus Fumigatus, Human and Bacterial Chitinases
Chem.Biol., 12, 2005
1WAW
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Specificity and affinity of natural product cyclopentapeptide inhibitor Argadin against human chitinase
分子名称: ARGADIN, CHITOTRIOSIDASE 1, GLYCEROL, ...
著者Rao, F.V, Houston, D.R, Boot, R.G, Aerts, J.M.F.G, Hodkinson, M, Adams, D.J, Shiomi, K, Omura, S, van Aalten, D.M.F.
登録日2004-10-28
公開日2005-01-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Specificity and Affinity of Natural Product Cyclopentapeptide Inhibitors Against Aspergillus Fumigatus, Human and Bacterial Chitinases
Chem.Biol., 12, 2005
1W9P
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Specificity and affinity of natural product cyclopentapeptide inhibitors against Aspergillus fumigatus, human and bacterial chitinaseFra
分子名称: CHITINASE, SULFATE ION
著者Rao, F.V, Houston, D.R, Boot, R.G, Aerts, J.M.F.G, Hodkinson, M, Adams, D.J, Shiomi, K, Omura, S, Van Aalten, D.M.F.
登録日2004-10-15
公開日2004-10-29
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Specificity and Affinity of Natural Product Cyclopentapeptide Inhibitors Against Aspergillus Fumigatus, Human and Bacterial Chitinases
Chem.Biol., 12, 2005
1WB0
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specificity and affinity of natural product cyclopentapeptide inhibitor Argifin against human chitinase
分子名称: ARGIFIN, CHITOTRIOSIDASE 1, GLYCEROL, ...
著者Rao, F.V, Houston, D.R, Boot, R.G, Aerts, J.M.F.G, Hodkinson, M, Adams, D.J, Shiomi, K, Omura, S, Van Aalten, D.M.F.
登録日2004-10-29
公開日2005-01-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Specificity and Affinity of Natural Product Cyclopentapeptide Inhibitors Against Aspergillus Fumigatus, Human and Bacterial Chitinases
Chem.Biol., 12, 2005
1IEN
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SOLUTION STRUCTURE OF TIA
分子名称: PROTEIN TIA
著者Sharpe, I.A, Gehrmann, J, Loughnan, M.L, Thomas, L, Adams, D.A, Atkins, A, Palant, E, Craik, D.J, Adams, D.J, Alewood, P.F, Lewis, R.J.
登録日2001-04-10
公開日2002-04-03
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Two new classes of conopeptides inhibit the alpha1-adrenoceptor and noradrenaline transporter.
Nat.Neurosci., 4, 2001
1IEO
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BU of 1ieo by Molmil
SOLUTION STRUCTURE OF MRIB-NH2
分子名称: PROTEIN MRIB-NH2
著者Sharpe, I.A, Gehrmann, J, Loughnan, M.L, Thomas, L, Adams, D.A, Atkins, A, Palant, E, Craik, D.J, Adams, D.J, Alewood, P.F, Lewis, R.J.
登録日2001-04-10
公開日2002-04-03
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Two new classes of conopeptides inhibit the alpha1-adrenoceptor and noradrenaline transporter.
Nat.Neurosci., 4, 2001
2AJW
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BU of 2ajw by Molmil
Structure of the cyclic conotoxin MII-6
分子名称: Alpha-conotoxin MII
著者Clark, R.J, Fischer, H, Dempster, L, Daly, N.L, Rosengren, K.J, Nevin, S.T, Meunier, F.A, Adams, D.J, Craik, D.J.
登録日2005-08-02
公開日2005-09-06
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Engineering stable peptide toxins by means of backbone cyclization: Stabilization of the {alpha}-conotoxin MII.
Proc.Natl.Acad.Sci.USA, 102, 2005
2AK0
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Structure of cyclic conotoxin MII-7
分子名称: Alpha-conotoxin MII
著者Clark, R.J, Fischer, H, Dempster, L, Daly, N.L, Rosengren, K.J, Nevin, S.T, Meunier, F.A, Adams, D.J, Craik, D.J.
登録日2005-08-02
公開日2005-09-06
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Engineering stable peptide toxins by means of backbone cyclization: Stabilization of the {alpha}-conotoxin MII.
Proc.Natl.Acad.Sci.USA, 102, 2005
1R9I
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BU of 1r9i by Molmil
NMR Solution Structure of PIIIA toxin, NMR, 20 structures
分子名称: Mu-conotoxin PIIIA
著者Nielsen, K.J, Watson, M, Adams, D.J, Hammarstrom, A.K, Gage, P.W, Hill, J.M, Craik, D.J, Thomas, L, Adams, D, Alewood, P.F, Lewis, R.J.
登録日2003-10-30
公開日2003-11-18
最終更新日2019-12-25
実験手法SOLUTION NMR
主引用文献Solution structure of mu-conotoxin PIIIA, a preferential inhibitor of persistent tetrodotoxin-sensitive sodium channels
J.Biol.Chem., 277, 2002
1RMK
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BU of 1rmk by Molmil
Solution structure of conotoxin MrVIB
分子名称: Mu-O-conotoxin MrVIB
著者Daly, N.L, Ekberg, J.A, Thomas, L, Adams, D.J, Lewis, R.J, Craik, D.J.
登録日2003-11-28
公開日2004-09-07
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Structures of muO-conotoxins from Conus marmoreus. Inhibitors of tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels in mammalian sensory neurons
J.Biol.Chem., 279, 2004
1TTL
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BU of 1ttl by Molmil
Omega-conotoxin GVIA, a N-type calcium channel blocker
分子名称: Omega-conotoxin GVIA
著者Mould, J, Yasuda, T, Schroeder, C.I, Beedle, A.M, Doering, C.J, Zamponi, G.W, Adams, D.J, Lewis, R.J.
登録日2004-06-23
公開日2004-07-13
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献The alpha2delta auxiliary subunit reduces affinity of omega-conotoxins for recombinant N-type (Cav2.2) calcium channels
J.Biol.Chem., 279, 2004
1TR6
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BU of 1tr6 by Molmil
NMR solution structure of omega-conotoxin [K10]GVIA, a cyclic cysteine knot peptide
分子名称: Omega-conotoxin GVIA
著者Mould, J, Yasuda, T, Schroeder, C.I, Beedle, A.M, Doering, C.J, Zamponi, G.W, Adams, D.J, Lewis, R.J.
登録日2004-06-21
公開日2004-07-13
最終更新日2011-10-05
実験手法SOLUTION NMR
主引用文献The alpha2delta auxiliary subunit reduces affinity of omega-conotoxins for recombinant N-type (Cav2.2) calcium channels
J.Biol.Chem., 279, 2004
2MSO
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BU of 2mso by Molmil
Solution study of cGm9a
分子名称: Conotoxin Gm9.1
著者Akcan, M, Clark, R.J, Daly, N.L, Conibear, A.C, de Faoite, A.C, Heghinian, M.C, Adams, D.J, Mari, F, Craik, D.J.
登録日2014-08-05
公開日2015-07-22
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Transforming conotoxins into cyclotides: Backbone cyclization of P-superfamily conotoxins.
Biopolymers, 104, 2015
2MSQ
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BU of 2msq by Molmil
Solution study of cBru9a
分子名称: Conotoxin cBru9a
著者Akcan, M, Clark, R.J, Daly, N.L, Conibear, A.C, de Faoite, A.C, Heghinian, M.C, Adams, D.J, Mari, F, Craik, D.J.
登録日2014-08-05
公開日2015-07-22
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Transforming conotoxins into cyclotides: Backbone cyclization of P-superfamily conotoxins.
Biopolymers, 104, 2015
2NS3
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BU of 2ns3 by Molmil
Solution structure of ribbon BuIA
分子名称: Alpha-conotoxin BuIA
著者Jin, A.H, Brandstaetter, H, Nevin, S.T, Tan, C.C, Clark, R.J, Adams, D.J, Alewood, P.F, Craik, D.J, Daly, N.L.
登録日2006-11-03
公開日2007-09-25
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Structure of alpha-conotoxin BuIA: influences of disulfide connectivity on structural dynamics
Bmc Struct.Biol., 7, 2007
2H8S
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Solution structure of alpha-conotoxin Vc1.1
分子名称: Alpha-conotoxin Vc1A
著者Clark, R.J, Fischer, H, Nevin, S.T, Adams, D.J, Craik, D.J.
登録日2006-06-07
公開日2006-06-27
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献The Synthesis, Structural Characterization, and Receptor Specificity of the {alpha}-Conotoxin Vc1.1.
J.Biol.Chem., 281, 2006
1N0Z
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BU of 1n0z by Molmil
Solution structure of the first zinc-finger domain from ZNF265
分子名称: ZINC ION, ZNF265
著者Plambeck, C.A, Fairley, K, Kwan, A.H.Y, Westman, B.J, Adams, D, Morris, B, Mackay, J.P.
登録日2002-10-15
公開日2003-07-22
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The structure of the zinc finger domain from human splicing factor ZNF265 fold
J.BIOL.CHEM., 278, 2003
4X9Z
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Dimeric conotoxin alphaD-GeXXA
分子名称: alphaD-conotoxin GeXXA from the venom of Conus generalis
著者Xu, S, Zhang, T, Kompella, S, Adams, D, Ding, J, Wang, C.
登録日2014-12-12
公開日2015-12-02
最終更新日2020-02-05
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Conotoxin alpha D-GeXXA utilizes a novel strategy to antagonize nicotinic acetylcholine receptors
Sci Rep, 5, 2015
6RPX
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Cytokine receptor-like factor 3 C-terminus residues 174-442: native
分子名称: Cytokine receptor-like factor 3
著者Mifsud, R.W, Yan, Y, Bennett, C, Read, R.J.
登録日2019-05-15
公開日2020-03-25
最終更新日2022-10-05
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献CRLF3 plays a key role in the final stage of platelet genesis and is a potential therapeutic target for thrombocythemia.
Blood, 139, 2022

 

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