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2FVV
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Human Diphosphoinositol polyphosphate phosphohydrolase 1
分子名称: CHLORIDE ION, Diphosphoinositol polyphosphate phosphohydrolase 1, INOSITOL HEXAKISPHOSPHATE, ...
著者Hallberg, B.M, Kursula, P, Ogg, D, Arrowsmith, C, Berglund, H, Edwards, A, Ehn, M, Flodin, S, Graslund, S, Hammarstrom, M, Hogbom, M, Holmberg-Schiavone, L, Kotenyova, T, Nilsson-Ehle, P, Nordlund, P, Nyman, T, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, van den Berg, S, Weigelt, J, Persson, C, Structural Genomics Consortium (SGC)
登録日2006-01-31
公開日2006-03-11
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Crystal structure of human diphosphoinositol phosphatase 1
Proteins, 77, 2009
2FW2
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Catalytic domain of CDY
分子名称: Testis-specific chromodomain protein Y 2
著者Min, J.R, Antoshenko, T, Wu, H, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2006-01-31
公開日2006-02-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Crystal Structure of catalytic domain of Human Testis-specific chromodomain protein Y.
To be Published
5C2L
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Magnesium soaked into the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
分子名称: Anthranilate phosphoribosyltransferase, IMIDAZOLE, MAGNESIUM ION
著者Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2015-06-16
公開日2016-06-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.009 Å)
主引用文献Binding and mimicking of the phosphate-rich substrate, PRPP
To Be Published
2GF9
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Crystal structure of human RAB3D in complex with GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-3D, ...
著者Hong, B, Wang, J, Shen, L, Tempel, W, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2006-03-21
公開日2006-05-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Crystal structure of human RAB3D in complex with GDP
To be Published
2FVZ
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Human Inositol Monophosphosphatase 2
分子名称: Inositol monophosphatase 2
著者Ogg, D, Hallberg, B.M, Arrowsmith, C, Berglund, H, Collins, R, Edwards, A, Ehn, M, Flodin, S, Graslund, S, Hammarstrom, M, Hogbom, M, Holmberg-Schiavone, L, Kotenyova, T, Kursula, P, Nilsson-Ehle, P, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Van Den Berg, S, Weigelt, J, Thorsell, A.G, Structural Genomics Consortium (SGC)
登録日2006-01-31
公開日2006-02-21
最終更新日2018-05-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of Human Inositol Monophosphatase 2
To be published
2IIP
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Human Nicotinamide N-methyltransferase
分子名称: Nicotinamide N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
著者Bernstein, G, Min, J, Wu, H, Tempel, W, Zeng, H, Loppnau, P, Avvakumov, G.V, Wasney, G, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2006-09-28
公開日2006-10-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献The Crystal Structure of Human Nicotinamide N-methyltransferase in complex with SAH
To be Published
2IG7
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Crystal structure of Human Choline Kinase B
分子名称: Choline/ethanolamine kinase, UNKNOWN ATOM OR ION
著者Rabeh, W.M, Tempel, W, Nedyalkova, L, Wasney, G, Landry, R, Vedadi, M, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2006-09-22
公開日2006-10-10
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of Human Choline Kinase B
To be Published
5C7S
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PRPP complexed with two Mn2+ in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Anthranilate phosphoribosyltransferase, MANGANESE (II) ION
著者Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2015-06-24
公開日2016-06-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Binding and mimicking of the phosphate-rich substrate, PRPP
To Be Published
2IJA
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BU of 2ija by Molmil
Human N-acetyltransferase 1 F125S mutant
分子名称: ACETAMIDE, Arylamine N-acetyltransferase 1, SODIUM ION, ...
著者Tempel, W, Wu, H, Dombrovski, L, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Grant, D.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2006-09-29
公開日2006-11-28
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.701 Å)
主引用文献The Crystal Structure of Human N-acetyltransferase 1 mutant, F125S
To be Published
2I4I
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Crystal Structure of human DEAD-box RNA helicase DDX3X
分子名称: ADENOSINE MONOPHOSPHATE, ATP-dependent RNA helicase DDX3X
著者Hogbom, M, Karlberg, T, Arrowsmith, C, Berglund, H, Busam, R.D, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hallberg, B.M, Hammarstrom, M, Johansson, I, Kotenyova, T, Magnusdottir, A, Nilsson-Ehle, P, Nordlund, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Uppenberg, J, Van Den Berg, S, Wallden, K, Weigelt, J, Welin, M, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC)
登録日2006-08-22
公開日2006-09-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of Conserved Domains 1 and 2 of the Human DEAD-box Helicase DDX3X in Complex with the Mononucleotide AMP
J.Mol.Biol., 372, 2007
4ZOK
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BU of 4zok by Molmil
Methylsulfonyl-containing inhibitor bound in the substrate capture site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 4-methyl-2-{[2-methyl-6-(methylsulfonyl)phenyl]amino}benzoic acid, Anthranilate phosphoribosyltransferase, ...
著者Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2015-05-06
公開日2016-05-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Inhibitor bound in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD).
To be Published
2G0N
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BU of 2g0n by Molmil
The Crystal Structure of the Human RAC3 in complex with GDP and Chloride
分子名称: CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Ugochukwu, E, Yang, X, Zao, Y, Elkins, J, Gileadi, C, Burgess, N, Colebrook, S, Gileadi, O, Fedorov, O, Bunkoczi, G, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, von Delft, F, Doyle, D, Structural Genomics Consortium (SGC)
登録日2006-02-13
公開日2006-05-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Crystal Structure of the Human RAC3 in complex with GDP and Chloride
To be Published
2G76
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BU of 2g76 by Molmil
Crystal structure of human 3-phosphoglycerate dehydrogenase
分子名称: D-3-phosphoglycerate dehydrogenase, D-MALATE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Turnbull, A.P, Salah, E, Savitsky, P, Gileadi, O, von Delft, F, Edwards, A, Arrowsmith, C, Weigelt, J, Sundstrom, M, Oppermann, U, Structural Genomics Consortium (SGC)
登録日2006-02-27
公開日2006-03-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of human 3-phosphoglycerate dehydrogenase
To be Published
2FV8
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The crystal structure of RhoB in the GDP-bound state
分子名称: GUANOSINE-5'-DIPHOSPHATE, Rho-related GTP-binding protein RhoB
著者Turnbull, A.P, Soundararajan, M, Smee, C, Johansson, C, Schoch, G, Gorrec, F, Bray, J, Papagrigoriou, E, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Doyle, D, Structural Genomics Consortium (SGC)
登録日2006-01-30
公開日2006-02-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The crystal structure of RhoB in the GDP-bound state
To be Published
2H6D
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BU of 2h6d by Molmil
Protein Kinase Domain of the Human 5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK alpha-2 chain)
分子名称: 5'-AMP-activated protein kinase catalytic subunit alpha-2
著者Littler, D.R, Walker, J.R, Wybenga-Groot, L, Newman, E.M, Butler-Cole, C, Mackenzie, F, Finerty, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2006-05-31
公開日2006-06-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A conserved mechanism of autoinhibition for the AMPK kinase domain: ATP-binding site and catalytic loop refolding as a means of regulation.
Acta Crystallogr.,Sect.F, 66, 2010
2HE3
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BU of 2he3 by Molmil
Crystal structure of the selenocysteine to cysteine mutant of human glutathionine peroxidase 2 (GPX2)
分子名称: CHLORIDE ION, Glutathione peroxidase 2
著者Johansson, C, Kavanagh, K.L, Rojkova, A, Gileadi, O, von Delft, F, Arrowsmith, C, Weigelt, J, Sundstrom, M, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC)
登録日2006-06-21
公開日2006-07-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the selenocysteine to cysteine mutant of human glutathionine peroxidase 2 (GPX2)
To be Published
2I1N
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Crystal structure of the 1st PDZ domain of Human DLG3
分子名称: Discs, large homolog 3, SODIUM ION
著者Turnbull, A.P, Phillips, C, Bunkoczi, G, Debreczeni, J, Ugochukwu, E, Pike, A.C.W, Gorrec, F, Umeano, C, Elkins, J, Berridge, G, Savitsky, P, Gileadi, O, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Doyle, D, Structural Genomics Consortium (SGC)
登録日2006-08-14
公開日2006-09-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007
2I9P
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Crystal structure of human hydroxyisobutyrate dehydrogenase complexed with NAD+
分子名称: 3-hydroxyisobutyrate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Kavanagh, K.L, Papagrigoriou, E, Salah, E, Lukacik, P, Smee, C, Burgess, N, von Delft, F, Weigelt, J, Arrowsmith, C, Sundstrom, M, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC)
登録日2006-09-06
公開日2006-09-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal structure of human hydroxyisobutyrate dehydrogenase complexed with NAD+
To be Published
2I62
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Mouse Nicotinamide N-methyltransferase
分子名称: Nicotinamide N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
著者Min, J, Wu, H, Zeng, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2006-08-27
公開日2006-09-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Crystal Structure of Mouse Nicotinamide N-methyltransferase in complex with SAH
To be Published
2B70
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T4 Lysozyme mutant L99A at ambient pressure
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme
著者Collins, M.D, Quillin, M.L, Matthews, B.W, Gruner, S.M, TB Structural Genomics Consortium (TBSGC)
登録日2005-10-03
公開日2005-11-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Cooperative water filling of a nonpolar protein cavity observed by high-pressure crystallography and simulation
Proc.Natl.Acad.Sci.Usa, 102, 2005
2FN4
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The crystal structure of human Ras-related protein, RRAS, in the GDP-bound state
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein R-Ras
著者Turnbull, A.P, Elkins, J.M, Gileadi, C, Burgess, N, Salah, E, Papagrigoriou, E, Debreczeni, J, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Doyle, D, Structural Genomics Consortium (SGC)
登録日2006-01-10
公開日2006-01-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The crystal structure of human Ras-related protein, RRAS, in the GDP-bound state
To be Published
2JRZ
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Solution structure of the Bright/ARID domain from the human JARID1C protein.
分子名称: Histone demethylase JARID1C
著者Koehler, C, Bishop, S, Dowler, E.F, Diehl, A, Schmieder, P, Leidert, M, Sundstrom, M, Arrowsmith, C.H, Wiegelt, J, Edwards, A, Oschkinat, H, Ball, L.J, Structural Genomics Consortium (SGC)
登録日2007-06-29
公開日2007-07-10
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Backbone and sidechain 1H, 13C and 15N resonance assignments of the Bright/ARID domain from the human JARID1C (SMCX) protein.
Biomol.Nmr Assign., 2, 2008
2H5G
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BU of 2h5g by Molmil
Crystal structure of human pyrroline-5-carboxylate synthetase
分子名称: Delta 1-pyrroline-5-carboxylate synthetase, SULFATE ION
著者Papagrigoriou, E, Shafqat, N, Turnbull, A.P, Berridge, G, Hozjan, V, Kavanagh, K, Gileadi, O, Smee, C, Bray, J, Gorrec, F, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC)
登録日2006-05-26
公開日2006-06-23
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structure of human pyrroline-5-carboxylate synthetase
To be published
2H63
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Crystal Structure of Human Biliverdin Reductase A
分子名称: Biliverdin reductase A, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Kavanagh, K, Elkins, J, Ugochukwu, E, Guo, K, Pilka, E, Lukacik, P, Smee, C, Papagrigoriou, E, Bunkoczi, G, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, von Delft, F, Oppermann, U, Structural Genomics Consortium (SGC)
登録日2006-05-30
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structure of Human Biliverdin Reductase A
To be Published
2GRY
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Crystal structure of the human KIF2 motor domain in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF2, MAGNESIUM ION, ...
著者Wang, J, Shen, Y, Tempel, W, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2006-04-25
公開日2006-05-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal structure of the human KIF2 motor domain in complex with ADP
to be published

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