5L1H
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![BU of 5l1h by Molmil](/molmil-images/mine/5l1h) | AMPA subtype ionotropic glutamate receptor GluA2 in complex with noncompetitive inhibitor GYKI53655 | 分子名称: | (8R)-5-(4-aminophenyl)-N,8-dimethyl-8,9-dihydro-2H,7H-[1,3]dioxolo[4,5-h][2,3]benzodiazepine-7-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2 | 著者 | Yelshanskaya, M.V, Singh, A.K, Sampson, J.M, Sobolevsky, A.I. | 登録日 | 2016-07-29 | 公開日 | 2016-10-19 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.801 Å) | 主引用文献 | Structural Bases of Noncompetitive Inhibition of AMPA-Subtype Ionotropic Glutamate Receptors by Antiepileptic Drugs. Neuron, 91, 2016
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5KO8
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![BU of 5ko8 by Molmil](/molmil-images/mine/5ko8) | Crystal structure of haliscomenobacter hydrossis iodotyrosine deiodinase (IYD) bound to FMN and mono-iodotyrosine (I-Tyr) | 分子名称: | 3-IODO-TYROSINE, FLAVIN MONONUCLEOTIDE, Nitroreductase | 著者 | Ingavat, N, Kavran, J.M, Sun, Z, Rokita, S.E. | 登録日 | 2016-06-29 | 公開日 | 2017-02-15 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Active Site Binding Is Not Sufficient for Reductive Deiodination by Iodotyrosine Deiodinase. Biochemistry, 56, 2017
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2VH9
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![BU of 2vh9 by Molmil](/molmil-images/mine/2vh9) | CRYSTAL STRUCTURE OF NXG1-DELTAYNIIG IN COMPLEX WITH XLLG, A XYLOGLUCAN DERIVED OLIGOSACCHARIDE | 分子名称: | CELLULASE, GLYCEROL, ZINC ION, ... | 著者 | Czjzek, M, Mark, P, Baumann, M.J, Eklof, J.M, Michel, G, Brumer, H. | 登録日 | 2007-11-20 | 公開日 | 2008-11-25 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Analysis of Nasturtium Tmnxg1 Complexes by Crystallography and Molecular Dynamics Provides Detailed Insight Into Substrate Recognition by Family Gh16 Xyloglucan Endo-Transglycosylases and Endo-Hydrolases. Proteins, 75, 2009
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5L1B
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![BU of 5l1b by Molmil](/molmil-images/mine/5l1b) | AMPA subtype ionotropic glutamate receptor GluA2 in Apo state | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2,Glutamate receptor 2 | 著者 | Yelshanskaya, M.V, Singh, A.K, Sampson, J.M, Sobolevsky, A.I. | 登録日 | 2016-07-28 | 公開日 | 2016-10-19 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Structural Bases of Noncompetitive Inhibition of AMPA-Subtype Ionotropic Glutamate Receptors by Antiepileptic Drugs. Neuron, 91, 2016
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2V13
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![BU of 2v13 by Molmil](/molmil-images/mine/2v13) | Crystal Structure of Renin with Inhibitor 7 | 分子名称: | N-[(2R,4S,5S,7R)-4-AMINO-8-(BUTYLAMINO)-5-HYDROXY-2,7-DIMETHYL-8-OXOOCTYL]-2-(3-METHOXYPROPOXY)BENZAMIDE, RENIN | 著者 | Rahuel, J, Rasetti, V, Maibaum, J, Rueger, H, Goschke, R, Cohen, N.C, Stutz, S, Cumin, F, Fuhrer, W, Wood, J.M, Grutter, M.G. | 登録日 | 2007-05-21 | 公開日 | 2008-07-08 | 最終更新日 | 2019-04-03 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure-Based Drug Design: The Discovery of Novel Nonpeptide Orally Active Inhibitors of Human Renin Chem.Biol., 7, 2000
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5KY0
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2V11
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![BU of 2v11 by Molmil](/molmil-images/mine/2v11) | Crystal Structure of Renin with Inhibitor 6 | 分子名称: | (2S,4S,5R,7R)-4-AMINO-8-(BUTYLAMINO)-5-HYDROXY-2,7-DIMETHYL-8-OXOOCTYL 1-BENZYL-1H-INDOLE-3-CARBOXYLATE, RENIN | 著者 | Rahuel, J, Rasetti, V, Maibaum, J, Rueger, H, Goschke, R, Cohen, N.C, Stutz, S, Cumin, F, Fuhrer, W, Wood, J.M, Grutter, M.G. | 登録日 | 2007-05-21 | 公開日 | 2007-07-03 | 最終更新日 | 2019-04-03 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structure-Based Drug Design: The Discovery of Novel Nonpeptide Orally Active Inhibitors of Human Renin Chem.Biol., 7, 2000
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5ISH
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![BU of 5ish by Molmil](/molmil-images/mine/5ish) | Crystal structure of mouse CARM1 in complex with inhibitor SA0765 | 分子名称: | 1,2-DIMETHOXYETHANE, 1,2-ETHANEDIOL, 1-METHOXY-2-(2-METHOXYETHOXY)ETHANE, ... | 著者 | Cura, V, Marechal, N, Mailliot, J, Troffer-Charlier, N, Hassenboehler, P, Wurtz, J.M, Bonnefond, L, Cavarelli, J. | 登録日 | 2016-03-15 | 公開日 | 2017-03-15 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.152 Å) | 主引用文献 | Crystal structure of mouse CARM1 in complex with inhibitor SA0765 To Be Published
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5ISE
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![BU of 5ise by Molmil](/molmil-images/mine/5ise) | Crystal structure of mouse CARM1 in complex with inhibitor SA0649 | 分子名称: | 1,2-DIMETHOXYETHANE, 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, ... | 著者 | Cura, V, Marechal, N, Mailliot, J, Troffer-Charlier, N, Hassenboehler, P, Wurtz, J.M, Bonnefond, L, Cavarelli, J. | 登録日 | 2016-03-15 | 公開日 | 2017-03-15 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of mouse CARM1 in complex with SAH at 1.8 Angstroms resolution To Be Published
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2WD1
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![BU of 2wd1 by Molmil](/molmil-images/mine/2wd1) | Human c-Met Kinase in complex with azaindole inhibitor | 分子名称: | 1-[(2-NITROPHENYL)SULFONYL]-1H-PYRROLO[3,2-B]PYRIDINE-6-CARBOXAMIDE, GAMMA-BUTYROLACTONE, HEPATOCYTE GROWTH FACTOR RECEPTOR | 著者 | Porter, J, Lumb, S, Franklin, R.J, Gascon-Simorte, J.M, Calmiano, M, Le Riche, K, Lallemand, B, Keyaerts, J, Edwards, H, Maloney, A, Delgado, J, King, L, Foley, A, Lecomte, F, Reuberson, J, Meier, C, Batchelor, M. | 登録日 | 2009-03-19 | 公開日 | 2009-04-28 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery of 4-Azaindoles as Novel Inhibitors of C- met Kinase. Bioorg.Med.Chem.Lett., 19, 2009
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5JEG
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![BU of 5jeg by Molmil](/molmil-images/mine/5jeg) | Human carbonic anhydrase II (V121I) complexed with benzo[d]thiazole-2-sulfonamide | 分子名称: | 1,3-benzothiazole-2-sulfonamide, Carbonic anhydrase 2, ZINC ION | 著者 | Fox, J.M, Kang, K, Sastry, M, Sherman, W, Sankaran, B, Zwart, P.H, Whitesides, G.M. | 登録日 | 2016-04-18 | 公開日 | 2017-01-11 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | 主引用文献 | Water-Restructuring Mutations Can Reverse the Thermodynamic Signature of Ligand Binding to Human Carbonic Anhydrase. Angew. Chem. Int. Ed. Engl., 56, 2017
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5JEP
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![BU of 5jep by Molmil](/molmil-images/mine/5jep) | Human carbonic anhydrase II (T199S) complexed with benzo[d]thiazole-2-sulfonamide | 分子名称: | 1,3-benzothiazole-2-sulfonamide, Carbonic anhydrase 2, ZINC ION | 著者 | Fox, J.M, Kang, K, Sastry, M, Sherman, W, Sankaran, B, Zwart, P.H, Whitesides, G.M. | 登録日 | 2016-04-18 | 公開日 | 2017-01-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | 主引用文献 | Water-Restructuring Mutations Can Reverse the Thermodynamic Signature of Ligand Binding to Human Carbonic Anhydrase. Angew. Chem. Int. Ed. Engl., 56, 2017
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5J4I
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5J60
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![BU of 5j60 by Molmil](/molmil-images/mine/5j60) | Structure of a thioredoxin reductase from Gloeobacter violaceus | 分子名称: | CALCIUM ION, FLAVIN-ADENINE DINUCLEOTIDE, TETRAETHYLENE GLYCOL, ... | 著者 | Buey, R.M, de Pereda, J.M, Balsera, M. | 登録日 | 2016-04-04 | 公開日 | 2016-07-27 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A New Member of the Thioredoxin Reductase Family from Early Oxygenic Photosynthetic Organisms. Mol Plant, 10, 2017
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2W3Z
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![BU of 2w3z by Molmil](/molmil-images/mine/2w3z) | Structure of a Streptococcus mutans CE4 esterase | 分子名称: | PHOSPHATE ION, PUTATIVE DEACETYLASE, ZINC ION | 著者 | Deng, D.M, Urch, J.E, ten Cate, J.M, Rao, V.A, van Aalten, D.M.F, Crielaard, W. | 登録日 | 2008-11-17 | 公開日 | 2008-12-02 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Streptococcus Mutans Smu.623C Codes for a Functional, Metal Dependent Polysaccharide Deacetylase that Modulates Interactions with Salivary Agglutinin. J.Bacteriol., 191, 2009
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2WLZ
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![BU of 2wlz by Molmil](/molmil-images/mine/2wlz) | Chitinase A from Serratia marcescens ATCC990 in complex with Chitobio- thiazoline. | 分子名称: | 1,4-DIETHYLENE DIOXIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL, ... | 著者 | Taylor, E.J, Dennis, R.J, Macdonald, J.M, Tarling, C.A, Knapp, S, Withers, S.G, Davies, G.J. | 登録日 | 2009-06-29 | 公開日 | 2010-03-16 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Chitinase Inhibition by Chitobiose and Chitotriose Thiazolines. Angew.Chem.Int.Ed.Engl., 49, 2010
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2WO8
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![BU of 2wo8 by Molmil](/molmil-images/mine/2wo8) | MMP12 complex with a beta hydroxy carboxylic acid | 分子名称: | (3S)-5-biphenyl-4-yl-3-hydroxypentanoic acid, CALCIUM ION, GLYCEROL, ... | 著者 | Holmes, I.P, Gaines, S, Watson, S.P, Lorthioir, O, Walker, A, Baddeley, S.J, Herbert, S, Egan, D, Convery, M.A, Singh, O.M.P, Gross, J.W, Strelow, J.M, Smith, R.H, Amour, A.J, Brown, D, Martin, S.L. | 登録日 | 2009-07-22 | 公開日 | 2009-09-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The Identification of Beta-Hydroxy Carboxylic Acids as Selective Mmp-12 Inhibitors. Bioorg.Med.Chem.Lett., 19, 2009
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4OIA
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![BU of 4oia by Molmil](/molmil-images/mine/4oia) | Crystal Structure of ICAM-5 D1-D4 ectodomain fragment, Space Group P4322 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Recacha, R, Jimenez, D, Tian, L, Barredo, R, Ghamberg, C, Casasnovas, J.M. | 登録日 | 2014-01-19 | 公開日 | 2014-07-16 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Crystal structures of an ICAM-5 ectodomain fragment show electrostatic-based homophilic adhesions. Acta Crystallogr.,Sect.D, 70, 2014
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5KU0
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![BU of 5ku0 by Molmil](/molmil-images/mine/5ku0) | expanded poliovirus in complex with VHH 17B | 分子名称: | VHH 17B, VP1, VP2, ... | 著者 | Strauss, M, Schotte, L, Filman, D.J, Hogle, J.M. | 登録日 | 2016-07-12 | 公開日 | 2016-11-02 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Cryo-electron Microscopy Structures of Expanded Poliovirus with VHHs Sample the Conformational Repertoire of the Expanded State. J. Virol., 91, 2017
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2XXL
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![BU of 2xxl by Molmil](/molmil-images/mine/2xxl) | Crystal structure of drosophila Grass clip serine protease of Toll pathway | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GRAM-POSITIVE SPECIFIC SERINE PROTEASE, ... | 著者 | Kellenberger, C, Leone, P, Coquet, L, Jouenne, T, Reichhart, J.M, Roussel, A. | 登録日 | 2010-11-10 | 公開日 | 2011-02-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure-Function Analysis of Grass Clip Serine Protease Involved in Drosophila Toll Pathway Activation. J.Biol.Chem., 286, 2011
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5KVL
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![BU of 5kvl by Molmil](/molmil-images/mine/5kvl) | Humanized 10G4 anti-leukotriene C4 antibody Fab fragment in complex with leukotriene C4 | 分子名称: | (5~{S},6~{R},7~{E},9~{E},11~{Z},14~{Z})-6-[(2~{R})-2-[[(4~{S})-4-azanyl-5-oxidanyl-5-oxidanylidene-pentanoyl]amino]-3-( 2-hydroxy-2-oxoethylamino)-3-oxidanylidene-propyl]sulfanyl-5-oxidanyl-icosa-7,9,11,14-tetraenoic acid, 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | 著者 | Huxford, T, King, A, Fleming, J.K, Wojciak, J.M. | 登録日 | 2016-07-14 | 公開日 | 2017-05-24 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Humanized 10G4 anti-leukotriene C4 antibody Fab fragment in complex with leukotriene C4 To Be Published
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2XXS
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![BU of 2xxs by Molmil](/molmil-images/mine/2xxs) | Solution structure of the N-terminal domain of the Shigella type III secretion protein MxiG | 分子名称: | PROTEIN MXIG | 著者 | McDowell, M.A, Johnson, S, Deane, J.E, McDonnell, J.M, Lea, S.M. | 登録日 | 2010-11-11 | 公開日 | 2011-07-06 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and Functional Studies on the N-Terminal Domain of the Shigella Type III Secretion Protein Mxig. J.Biol.Chem., 286, 2011
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5KY2
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5L03
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![BU of 5l03 by Molmil](/molmil-images/mine/5l03) | Crystal structure of 2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE Synthase from BURKHOLDERIA PSEUDOMALLEI bound to L-tryptophan hydroxamate | 分子名称: | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, N-hydroxy-L-tryptophanamide, ZINC ION | 著者 | Blain, J.M, Ghose, D, Gorman, J.L, Goshu, G.M, Ranieri, G, Zhao, L, Bode, B, Meganathan, R, Walter, R.L, Hagen, T.J, Horn, J.R. | 登録日 | 2016-07-26 | 公開日 | 2017-11-08 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.469 Å) | 主引用文献 | Synthesis and Characterization of the Burkholderia pseudomallei IspF Inhibitor L-tryptophan hydroxamate To Be Published
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5L0U
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![BU of 5l0u by Molmil](/molmil-images/mine/5l0u) | |