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7NHC
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BU of 7nhc by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer - Endonuclease ordered (Class2b)
分子名称: Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-10
公開日2021-12-01
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.87 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NJ7
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BU of 7nj7 by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8200 core
分子名称: Nb8200 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-16
公開日2021-12-01
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (4.82 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NKA
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BU of 7nka by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8206
分子名称: NB8206, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-17
公開日2021-12-01
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (4.07 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NIL
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BU of 7nil by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8190 core
分子名称: Nanobody8190 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-12
公開日2021-12-01
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (5.01 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NFQ
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BU of 7nfq by Molmil
Fujian capmidlink domain in complex with Nb8193
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Nb8193, ...
著者Keown, J.R, Grimes, J.M, Fodor, E.
登録日2021-02-07
公開日2021-12-01
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NI0
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BU of 7ni0 by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer - Replicase (class 3)
分子名称: Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-11
公開日2021-12-01
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.32 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NIR
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BU of 7nir by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8191 core
分子名称: Nanobody8191 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-13
公開日2021-12-01
最終更新日2024-11-20
実験手法ELECTRON MICROSCOPY (6.7 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NK2
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BU of 7nk2 by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8202 core
分子名称: Nanobody8202, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-17
公開日2021-12-01
最終更新日2024-11-20
実験手法ELECTRON MICROSCOPY (4.84 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NJ4
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BU of 7nj4 by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8198 core
分子名称: Nb8198 Core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-16
公開日2021-12-01
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (5.84 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NK4
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BU of 7nk4 by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8203 core
分子名称: Nanobody 8203, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-17
公開日2021-12-01
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (5.32 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NJ3
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BU of 7nj3 by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8196 core
分子名称: Nanobody8196 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-15
公開日2021-12-01
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (4.48 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NK8
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BU of 7nk8 by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8205 core
分子名称: Nb8205, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-17
公開日2021-12-01
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (5.34 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
6HHD
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BU of 6hhd by Molmil
Mouse Prion Protein in complex with Nanobody 484
分子名称: CHLORIDE ION, GLYCEROL, Major prion protein, ...
著者Soror, S, Abskharon, R, Wohlkonig, A.
登録日2018-08-28
公開日2019-12-11
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.102 Å)
主引用文献Structural evidence for the critical role of the prion protein hydrophobic region in forming an infectious prion.
Plos Pathog., 15, 2019
6HHU
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BU of 6hhu by Molmil
Structure of the Bacillus anthracis Sap S-layer assembly domain
分子名称: Nanobody AF694, S-layer protein sap, nanobody AF684
著者Remaut, H, Fioravanti, A.
登録日2018-08-29
公開日2019-07-24
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of S-layer protein Sap reveals a mechanism for therapeutic intervention in anthrax.
Nat Microbiol, 4, 2019
6HER
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BU of 6her by Molmil
Mouse prion protein in complex with Nanobody 484
分子名称: GLYCEROL, Major prion protein, Nanobody 484, ...
著者Soror, S.H, Abskharon, R, Wohlkonig, A.
登録日2018-08-20
公開日2019-12-04
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.199 Å)
主引用文献Structural evidence for the critical role of the prion protein hydrophobic region in forming an infectious prion.
Plos Pathog., 15, 2019
8S5W
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BU of 8s5w by Molmil
Cryo-EM structure of fedratinib-bound human SLC19A3 in inward-open state
分子名称: N-tert-butyl-3-{[5-methyl-2-({4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}amino)pyrimidin-4-yl]amino}benzenesulfonamide, Nb3.7, Thiamine transporter 2
著者Gabriel, F, Loew, C.
登録日2024-02-26
公開日2024-10-02
最終更新日2024-12-04
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献Structural basis of thiamine transport and drug recognition by SLC19A3.
Nat Commun, 15, 2024
8S5U
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BU of 8s5u by Molmil
Cryo-EM structure of thiamine-bound human SLC19A3 in outward-open state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, Nb3.4, ...
著者Gabriel, F, Loew, C.
登録日2024-02-26
公開日2024-10-02
最終更新日2024-12-04
実験手法ELECTRON MICROSCOPY (3.28 Å)
主引用文献Structural basis of thiamine transport and drug recognition by SLC19A3.
Nat Commun, 15, 2024
8S5Z
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BU of 8s5z by Molmil
Cryo-EM structure of hydroxychloroquine-bound human SLC19A3 in inward-open state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hydroxychloroquine, Nb3.3, ...
著者Gabriel, F, Loew, C.
登録日2024-02-26
公開日2024-10-02
最終更新日2024-12-04
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of thiamine transport and drug recognition by SLC19A3.
Nat Commun, 15, 2024
8S61
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BU of 8s61 by Molmil
Cryo-EM structure of thiamine-bound human SLC19A3 in inward-open state
分子名称: 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, Nb3.7, Thiamine transporter 2
著者Gabriel, F, Loew, C.
登録日2024-02-26
公開日2024-10-02
最終更新日2024-12-04
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献Structural basis of thiamine transport and drug recognition by SLC19A3.
Nat Commun, 15, 2024
8S4U
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BU of 8s4u by Molmil
Cryo-EM structure of apo human SLC19A3 in outward-open state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody 3.4, Thiamine transporter 2
著者Gabriel, F, Loew, C.
登録日2024-02-22
公開日2024-10-02
最終更新日2024-12-04
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献Structural basis of thiamine transport and drug recognition by SLC19A3.
Nat Commun, 15, 2024
8S62
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BU of 8s62 by Molmil
Cryo-EM structure of amprolium-bound human SLC19A3 in inward-open state
分子名称: Amprolium, Nb3.7, Thiamine transporter 2
著者Gabriel, F, Loew, C.
登録日2024-02-26
公開日2024-10-02
最終更新日2024-12-04
実験手法ELECTRON MICROSCOPY (3.75 Å)
主引用文献Structural basis of thiamine transport and drug recognition by SLC19A3.
Nat Commun, 15, 2024
8RRS
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BU of 8rrs by Molmil
Structure of mouse RyR2 solubilised in detergent in open state in complex with Ca2+, ATP, caffeine and Nb9657.
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, CALCIUM ION, ...
著者Li, C, Efremov, R.G.
登録日2024-01-23
公開日2024-10-09
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Rapid small-scale nanobody-assisted purification of ryanodine receptors for cryo-EM.
J.Biol.Chem., 300, 2024
8RRW
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BU of 8rrw by Molmil
Structure of RyR1 in detergent in open state in complex with FKBP and Nb9657.
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, CALCIUM ION, ...
著者Li, C, Efremov, R.G.
登録日2024-01-23
公開日2024-10-09
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Rapid small-scale nanobody-assisted purification of ryanodine receptors for cryo-EM.
J.Biol.Chem., 300, 2024
8RRV
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BU of 8rrv by Molmil
Structure of RyR1 in detergent in close state in complex with FKBP and Nb9657.
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ZINC ION, ...
著者Li, C, Efremov, R.G.
登録日2024-01-23
公開日2024-10-09
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Rapid small-scale nanobody-assisted purification of ryanodine receptors for cryo-EM.
J.Biol.Chem., 300, 2024
8RRT
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BU of 8rrt by Molmil
Structure of rabbit RyR1 reconstituted into lipid liposomes in open state in complex with FKBP and Nb9657
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, CALCIUM ION, ...
著者Li, C, Efremov, R.G.
登録日2024-01-23
公開日2024-10-09
最終更新日2024-11-20
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Rapid small-scale nanobody-assisted purification of ryanodine receptors for cryo-EM.
J.Biol.Chem., 300, 2024

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件を2025-07-09に公開中

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