3DRQ
| Crystal structure of the HIV-1 broadly neutralizing antibody 2F5 in complex with the gp41 FP-MPER Hyb3K construct 514GIGALFLGFLGAAGS528KK-Ahx-655KNEQELLELDKWASLWN671 soaked in PEG/2-propanol solution | 分子名称: | 2F5 Fab' heavy chain, 2F5 Fab' light chain, GLYCEROL, ... | 著者 | Bryson, S, Julien, J.P, Pai, E.F. | 登録日 | 2008-07-11 | 公開日 | 2008-10-07 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural details of HIV-1 recognition by the broadly neutralizing monoclonal antibody 2F5: epitope conformation, antigen-recognition loop mobility, and anion-binding site. J.Mol.Biol., 384, 2008
|
|
3DBP
| Crystal Structure of Human Orotidine 5'-Monophosphate Decarboxylase Complexed with 6-NH2-UMP | 分子名称: | 6-AMINOURIDINE 5'-MONOPHOSPHATE, Orotidine 5'-phosphate decarboxylase, SULFATE ION | 著者 | Liu, Y, To, T, Bello, A.M, Kotra, L.P, Pai, E.F. | 登録日 | 2008-06-02 | 公開日 | 2009-06-23 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal Structure of Human Orotidine 5'-Monophosphate Decarboxylase Complexed with 6-NH2-UMP To be Published
|
|
6QKU
| Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Tyr219Phe - Chloroacetate soaked 2hr | 分子名称: | CHLORIDE ION, Fluoroacetate dehalogenase, GLYCOLIC ACID, ... | 著者 | Mehrabi, P, Kim, T.H, Prosser, R.S, Pai, E.F. | 登録日 | 2019-01-30 | 公開日 | 2019-06-26 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.511 Å) | 主引用文献 | Substrate-Based Allosteric Regulation of a Homodimeric Enzyme. J.Am.Chem.Soc., 141, 2019
|
|
6OEZ
| Crystal structure of Trypanothione Reductase from Trypanosoma brucei in complex with inhibitor (+)-N-(Cyclobutylmethyl)-3-{5-[1-(pyrrolidin-1-yl)cyclohexyl]-2-(1-{[(2S)-pyrro-lidin-2-yl]methyl}-1H-indol-5-yl)-1,3-thiazol-4-yl}prop-2-yn-1-amine | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, N-(cyclobutylmethyl)-3-{5-[1-(pyrrolidin-1-yl)cyclohexyl]-2-(1-{[(2S)-pyrrolidin-2-yl]methyl}-1H-indol-5-yl)-1,3-thiazol-4-yl}prop-2-yn-1-amine, ... | 著者 | Halgas, O, De Gasparo, R, Harangozo, D, Krauth-Siegel, R.L, Diederich, F, Pai, E.F. | 登録日 | 2019-03-28 | 公開日 | 2019-07-31 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Targeting a Large Active Site: Structure-Based Design of Nanomolar Inhibitors of Trypanosoma brucei Trypanothione Reductase. Chemistry, 25, 2019
|
|
6QHZ
| Time resolved structural analysis of the full turnover of an enzyme - 6788 ms | 分子名称: | Fluoroacetate dehalogenase, fluoroacetic acid | 著者 | Schulz, E.C, Mehrabi, P, Pai, E.F, Miller, D. | 登録日 | 2019-01-17 | 公開日 | 2019-09-25 | 実験手法 | X-RAY DIFFRACTION (1.799 Å) | 主引用文献 | Time-resolved crystallography reveals allosteric communication aligned with molecular breathing. Science, 365, 2019
|
|
6QHT
| Time resolved structural analysis of the full turnover of an enzyme - 376 ms | 分子名称: | Fluoroacetate dehalogenase, fluoroacetic acid | 著者 | Schulz, E.C, Mehrabi, P, Pai, E.F, Miller, D. | 登録日 | 2019-01-17 | 公開日 | 2019-09-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Time-resolved crystallography reveals allosteric communication aligned with molecular breathing. Science, 365, 2019
|
|
6QI2
| Time resolved structural analysis of the full turnover of an enzyme - 13536 ms | 分子名称: | Fluoroacetate dehalogenase, GLYCOLIC ACID | 著者 | Schulz, E.C, Mehrabi, P, Pai, E.F, Miller, D. | 登録日 | 2019-01-17 | 公開日 | 2019-09-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Time-resolved crystallography reveals allosteric communication aligned with molecular breathing. Science, 365, 2019
|
|
6QKW
| Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Tyr219Phe - Fluoroacetate soaked 2hr | 分子名称: | CHLORIDE ION, Fluoroacetate dehalogenase, GLYCOLIC ACID, ... | 著者 | Mehrabi, P, Kim, T.H, Prosser, R.S, Pai, E.F. | 登録日 | 2019-01-30 | 公開日 | 2019-06-26 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.512 Å) | 主引用文献 | Substrate-Based Allosteric Regulation of a Homodimeric Enzyme. J.Am.Chem.Soc., 141, 2019
|
|
6QHU
| Time resolved structural analysis of the full turnover of an enzyme - 100 ms | 分子名称: | Fluoroacetate dehalogenase, fluoroacetic acid | 著者 | Schulz, E.C, Mehrabi, P, Pai, E.F, Miller, D. | 登録日 | 2019-01-17 | 公開日 | 2019-09-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Time-resolved crystallography reveals allosteric communication aligned with molecular breathing. Science, 365, 2019
|
|
6QI1
| Time resolved structural analysis of the full turnover of an enzyme - 12312 ms | 分子名称: | Fluoroacetate dehalogenase, fluoroacetic acid | 著者 | Schulz, E.C, Mehrabi, P, Pai, E.F, Miller, D. | 登録日 | 2019-01-17 | 公開日 | 2019-09-25 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Time-resolved crystallography reveals allosteric communication aligned with molecular breathing. Science, 365, 2019
|
|
6QKT
| Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Tyr219Phe - Fluoroacetate soaked 24hr - Glycolate bound | 分子名称: | Fluoroacetate dehalogenase, GLYCOLIC ACID | 著者 | Mehrabi, P, Kim, T.H, Prosser, R.S, Pai, E.F. | 登録日 | 2019-01-30 | 公開日 | 2019-06-26 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.512 Å) | 主引用文献 | Substrate-Based Allosteric Regulation of a Homodimeric Enzyme. J.Am.Chem.Soc., 141, 2019
|
|
6QHY
| Time resolved structural analysis of the full turnover of an enzyme - 100 ms | 分子名称: | Fluoroacetate dehalogenase, fluoroacetic acid | 著者 | Schulz, E.C, Mehrabi, P, Pai, E.F, Miller, D. | 登録日 | 2019-01-17 | 公開日 | 2019-09-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | 主引用文献 | Time-resolved crystallography reveals allosteric communication aligned with molecular breathing. Science, 365, 2019
|
|
6QHP
| Time resolved structural analysis of the full turnover of an enzyme - 2256 ms covalent intermediate 1 | 分子名称: | Fluoroacetate dehalogenase, fluoroacetic acid | 著者 | Schulz, E.C, Mehrabi, P, Pai, E.F, Miller, D. | 登録日 | 2019-01-17 | 公開日 | 2019-09-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Time-resolved crystallography reveals allosteric communication aligned with molecular breathing. Science, 365, 2019
|
|
6QHX
| Time resolved structural analysis of the full turnover of an enzyme - 6156 ms | 分子名称: | Fluoroacetate dehalogenase, fluoroacetic acid | 著者 | Schulz, E.C, Mehrabi, P, Pai, E.F, Miller, D. | 登録日 | 2019-01-17 | 公開日 | 2019-09-25 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Time-resolved crystallography reveals allosteric communication aligned with molecular breathing. Science, 365, 2019
|
|
6QI3
| Time resolved structural analysis of the full turnover of an enzyme - 27072 ms | 分子名称: | Fluoroacetate dehalogenase, GLYCOLIC ACID | 著者 | Schulz, E.C, Mehrabi, P, Pai, E.F, Miller, D. | 登録日 | 2019-01-17 | 公開日 | 2019-09-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.739 Å) | 主引用文献 | Time-resolved crystallography reveals allosteric communication aligned with molecular breathing. Science, 365, 2019
|
|
6QHS
| Time resolved structural analysis of the full turnover of an enzyme - 564 ms | 分子名称: | Fluoroacetate dehalogenase, fluoroacetic acid | 著者 | Schulz, E.C, Mehrabi, P, Pai, E.F, Miller, D. | 登録日 | 2019-01-17 | 公開日 | 2019-09-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.733 Å) | 主引用文献 | Time-resolved crystallography reveals allosteric communication aligned with molecular breathing. Science, 365, 2019
|
|
6QI0
| Time resolved structural analysis of the full turnover of an enzyme - 9024 ms | 分子名称: | CALCIUM ION, Fluoroacetate dehalogenase, GLYCOLIC ACID, ... | 著者 | Schulz, E.C, Mehrabi, P, Pai, E.F, Miller, D. | 登録日 | 2019-01-17 | 公開日 | 2019-09-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.733 Å) | 主引用文献 | Time-resolved crystallography reveals allosteric communication aligned with molecular breathing. Science, 365, 2019
|
|
6QHQ
| Time resolved structural analysis of the full turnover of an enzyme - 1128 ms | 分子名称: | Fluoroacetate dehalogenase, fluoroacetic acid | 著者 | Schulz, E.C, Mehrabi, P, Pai, E.F, Miller, D. | 登録日 | 2019-01-17 | 公開日 | 2019-09-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.735 Å) | 主引用文献 | Time-resolved crystallography reveals allosteric communication aligned with molecular breathing. Science, 365, 2019
|
|
6QHW
| Time resolved structural analysis of the full turnover of an enzyme - 4512 ms | 分子名称: | Fluoroacetate dehalogenase, GLYCOLIC ACID, fluoroacetic acid | 著者 | Schulz, E.C, Mehrabi, P, Pai, E.F, Miller, D. | 登録日 | 2019-01-17 | 公開日 | 2019-09-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.718 Å) | 主引用文献 | Time-resolved crystallography reveals allosteric communication aligned with molecular breathing. Science, 365, 2019
|
|
6QHV
| Time resolved structural analysis of the full turnover of an enzyme - 100 ms | 分子名称: | Fluoroacetate dehalogenase, fluoroacetic acid | 著者 | Schulz, E.C, Mehrabi, P, Pai, E.F, Miller, D. | 登録日 | 2019-01-17 | 公開日 | 2019-09-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.715 Å) | 主引用文献 | Time-resolved crystallography reveals allosteric communication aligned with molecular breathing. Science, 365, 2019
|
|
6QKS
| Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Tyr219Phe - Apo | 分子名称: | CHLORIDE ION, Fluoroacetate dehalogenase | 著者 | Mehrabi, P, Kim, T.H, Prosser, R.S, Pai, E.F. | 登録日 | 2019-01-30 | 公開日 | 2019-06-26 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Substrate-Based Allosteric Regulation of a Homodimeric Enzyme. J.Am.Chem.Soc., 141, 2019
|
|
2O4D
| Crystal Structure of a hypothetical protein from Pseudomonas aeruginosa | 分子名称: | Hypothetical protein PA0269 | 著者 | McGrath, T.E, Battaile, K, Kisselman, G, Romanov, V, Wu-Brown, J, Virag, C, Ng, I, Kimber, M, Edwards, A.M, Pai, E.F, Chirgadze, N.Y. | 登録日 | 2006-12-04 | 公開日 | 2007-01-30 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal Structure of a hypothetical protein from Pseudomonas aeruginosa To be Published
|
|
2O1B
| Structure of aminotransferase from Staphylococcus aureus | 分子名称: | Aminotransferase, class I, PYRIDOXAL-5'-PHOSPHATE | 著者 | McGrath, T.E, Dharamsi, A, Thambipillai, D, Edwards, A.M, Pai, E.F, Chirgadze, N.Y. | 登録日 | 2006-11-28 | 公開日 | 2006-12-12 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structure of aminotransferase from Staphylococcus aureus To be Published
|
|
2P1F
| |
2P8M
| Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 in complex with gp41 Peptide ELLELDKWASLWN in new crystal form | 分子名称: | gp41 peptide, nmAb 2F5, heavy chain, ... | 著者 | Julien, J.P, Bryson, S, Pai, E.F. | 登録日 | 2007-03-22 | 公開日 | 2007-05-15 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural details of HIV-1 recognition by the broadly neutralizing monoclonal antibody 2F5: epitope conformation, antigen-recognition loop mobility, and anion-binding site. J.Mol.Biol., 384, 2008
|
|