5GOJ
| Lys63-linked di-ubiquitin | 分子名称: | D-ubiquitin, Ubiquitin | 著者 | Gao, S, Pan, M, Zheng, Y, Liu, L. | 登録日 | 2016-07-27 | 公開日 | 2016-11-02 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.549 Å) | 主引用文献 | Monomer/Oligomer Quasi-Racemic Protein Crystallography J.Am.Chem.Soc., 138, 2016
|
|
5GOH
| Lys33-linked di-ubiquitin | 分子名称: | D-ubiquitin, Ubiquitin | 著者 | Gao, S, Pan, M, Zheng, Y, Liu, L. | 登録日 | 2016-07-27 | 公開日 | 2016-11-02 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.946 Å) | 主引用文献 | Monomer/Oligomer Quasi-Racemic Protein Crystallography J.Am.Chem.Soc., 138, 2016
|
|
5GXU
| Cystal structure of Arabidopsis ATR2 | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADPH--cytochrome P450 reductase 2 | 著者 | Niu, G, Liu, L. | 登録日 | 2016-09-20 | 公開日 | 2017-01-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of the Arabidopsis thaliana NADPH-cytochrome P450 reductase 2 (ATR2) provides insight into its function FEBS J., 284, 2017
|
|
3F3H
| Crystal structure and anti-tumor activity of LZ-8 from the fungus Ganoderma lucidium | 分子名称: | Immunomodulatory protein Ling Zhi-8 | 著者 | Zhou, C.Z, Huang, L, He, Y.X, Bao, R, Sun, F, Liang, C, Liu, L. | 登録日 | 2008-10-30 | 公開日 | 2009-09-15 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of LZ-8 from the medicinal fungus Ganoderma lucidium Proteins, 75, 2009
|
|
5GOI
| Lys48-linked di-ubiquitin | 分子名称: | D-ubiquitin, Ubiquitin | 著者 | Gao, S, Pan, M, Zheng, Y, Liu, L. | 登録日 | 2016-07-27 | 公開日 | 2016-11-02 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.594 Å) | 主引用文献 | Monomer/Oligomer Quasi-Racemic Protein Crystallography J.Am.Chem.Soc., 138, 2016
|
|
8ZKC
| iron-sulfur cluster transfer protein ApbC | 分子名称: | GLYCEROL, Iron-sulfur cluster carrier protein, MAGNESIUM ION | 著者 | Yang, J, Liu, L. | 登録日 | 2024-05-16 | 公開日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Crystal structure of the iron-sulfur cluster transfer protein ApbC from Escherichia coli. Biochem.Biophys.Res.Commun., 722, 2024
|
|
7TQ7
| Structure of MERS 3CL protease in complex with the cyclopropane based inhibitor 13c | 分子名称: | N-{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-N~2~-({[(1R,2R)-2-propylcyclopropyl]methoxy}carbonyl)-L-leucinamide, Orf1a protein, TETRAETHYLENE GLYCOL | 著者 | Lovell, S, Liu, L, Battaile, K.P, Nguyen, H.N, Chamandi, S.D, Picard, H.R, Madden, T.K, Thruman, H.A, Kim, Y, Groutas, W.C, Chang, K.O. | 登録日 | 2022-01-26 | 公開日 | 2022-02-09 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Broad-Spectrum Cyclopropane-Based Inhibitors of Coronavirus 3C-like Proteases: Biochemical, Structural, and Virological Studies. Acs Pharmacol Transl Sci, 6, 2023
|
|
7TQ5
| Structure of SARS-CoV-2 3CL protease in complex with the cyclopropane based inhibitor 10d | 分子名称: | (1R,2S)-1-hydroxy-2-{[N-({[(1R,2R)-2-(4-methoxyphenyl)cyclopropyl]methoxy}carbonyl)-L-leucyl]amino}-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, (1S,2S)-1-hydroxy-2-{[N-({[(1R,2R)-2-(4-methoxyphenyl)cyclopropyl]methoxy}carbonyl)-L-leucyl]amino}-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase, ... | 著者 | Lovell, S, Liu, L, Battaile, K.P, Nguyen, H.N, Chamandi, S.D, Picard, H.R, Madden, T.K, Thruman, H.A, Kim, Y, Groutas, W.C, Chang, K.O. | 登録日 | 2022-01-26 | 公開日 | 2022-02-09 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Broad-Spectrum Cyclopropane-Based Inhibitors of Coronavirus 3C-like Proteases: Biochemical, Structural, and Virological Studies. Acs Pharmacol Transl Sci, 6, 2023
|
|
7TQ6
| Structure of SARS-CoV-2 3CL protease in complex with the cyclopropane based inhibitor 13d | 分子名称: | (1R,2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]-2-{[N-({[(1R,2R)-2-propylcyclopropyl]methoxy}carbonyl)-L-leucyl]amino}propane-1-sulfonic acid, (1S,2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]-2-{[N-({[(1R,2R)-2-propylcyclopropyl]methoxy}carbonyl)-L-leucyl]amino}propane-1-sulfonic acid, 3C-like proteinase, ... | 著者 | Lovell, S, Liu, L, Battaile, K.P, Nguyen, H.N, Chamandi, S.D, Picard, H.R, Madden, T.K, Thruman, H.A, Kim, Y, Groutas, W.C, Chang, K.O. | 登録日 | 2022-01-26 | 公開日 | 2022-02-09 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Broad-Spectrum Cyclopropane-Based Inhibitors of Coronavirus 3C-like Proteases: Biochemical, Structural, and Virological Studies. Acs Pharmacol Transl Sci, 6, 2023
|
|
7UDZ
| Designed pentameric proton channel LQLL | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, De novo designed pentameric proton channel LQLL | 著者 | Kratochvil, H.T, Thomaston, J.L, Mravic, M, Nicoludis, J.M, Liu, L, DeGrado, W.F. | 登録日 | 2022-03-20 | 公開日 | 2022-04-06 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Transient water wires mediate selective proton transport in designed channel proteins. Nat.Chem., 15, 2023
|
|
7UDX
| Designed pentameric proton channel QLQL | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, De novo designed pentameric proton channel QLQL | 著者 | Kratochvil, H.T, Thomaston, J.L, Liu, L, DeGrado, W.F. | 登録日 | 2022-03-20 | 公開日 | 2022-04-06 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | 主引用文献 | Transient water wires mediate selective proton transport in designed channel proteins. Nat.Chem., 15, 2023
|
|
7UDY
| Designed pentameric channel QLLL | 分子名称: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Designed channel QLLL | 著者 | Kratochvil, H.T, Thomaston, J.L, Liu, L, DeGrado, W.F. | 登録日 | 2022-03-20 | 公開日 | 2022-04-06 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Transient water wires mediate selective proton transport in designed channel proteins. Nat.Chem., 15, 2023
|
|
7UDW
| Designed pentameric proton channel QQLL | 分子名称: | De novo designed pentameric proton channel QQLL | 著者 | Kratochvil, H.T, Thomaston, J.L, Mravic, M, Nicoludis, J, Liu, L, DeGrado, W.F. | 登録日 | 2022-03-20 | 公開日 | 2022-04-06 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Transient water wires mediate selective proton transport in designed channel proteins. Nat.Chem., 15, 2023
|
|
7UDV
| |
1YJX
| Crystal structure of human B type phosphoglycerate mutase | 分子名称: | CHLORIDE ION, CITRIC ACID, Phosphoglycerate mutase 1 | 著者 | Wang, Y, Wei, Z, Liu, L, Gong, W. | 登録日 | 2005-01-16 | 公開日 | 2005-05-17 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of human B-type phosphoglycerate mutase bound with citrate. Biochem.Biophys.Res.Commun., 331, 2005
|
|
6D02
| Cross-alpha Amyloid-like Structure alphaAmL, 2nd form | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CARBONATE ION, PHOSPHATE ION, ... | 著者 | Zhang, S.-Q, Liu, L, Degrado, W.F. | 登録日 | 2018-04-10 | 公開日 | 2019-02-20 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Designed peptides that assemble into cross-alpha amyloid-like structures. Nat. Chem. Biol., 14, 2018
|
|
8HR1
| Cryo-EM structure of SSX1 bound to the unmodified nucleosome at a resolution of 3.02 angstrom | 分子名称: | DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... | 著者 | Zebin, T, Ai, H.S, Ziyu, X, Man, P, Liu, L. | 登録日 | 2022-12-14 | 公開日 | 2023-09-13 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | 主引用文献 | Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes. Nat.Struct.Mol.Biol., 31, 2024
|
|
8HQY
| Cryo-EM structure of SSX1 bound to the H2AK119Ub nucleosome at a resolution of 3.05 angstrom | 分子名称: | DNA (136-MER), DNA (137-MER), Histone H2A type 1-B/E, ... | 著者 | Zebin, T, Ai, H.S, Ziyu, X, GuoChao, C, Man, P, Liu, L. | 登録日 | 2022-12-14 | 公開日 | 2023-09-27 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes. Nat.Struct.Mol.Biol., 31, 2024
|
|
6ABO
| human XRCC4 and IFFO1 complex | 分子名称: | DNA repair protein XRCC4, GLYCEROL, Intermediate filament family orphan 1, ... | 著者 | Li, J, Liu, L, Liang, H, Liu, Y, Xu, D. | 登録日 | 2018-07-23 | 公開日 | 2019-07-31 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | The nucleoskeleton protein IFFO1 immobilizes broken DNA and suppresses chromosome translocation during tumorigenesis. Nat.Cell Biol., 21, 2019
|
|
1YFK
| Crystal structure of human B type phosphoglycerate mutase | 分子名称: | CHLORIDE ION, CITRIC ACID, Phosphoglycerate mutase 1 | 著者 | Wang, Y, Wei, Z, Liu, L, Gong, W. | 登録日 | 2005-01-02 | 公開日 | 2005-05-17 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of human B-type phosphoglycerate mutase bound with citrate. Biochem.Biophys.Res.Commun., 331, 2005
|
|
4ZDS
| Crystal Structure of core DNA binding domain of Arabidopsis Thaliana Transcription Factor Ethylene-Insensitive 3 | 分子名称: | Protein ETHYLENE INSENSITIVE 3 | 著者 | Song, J, Zhu, C, Zhang, X, Wen, X, Liu, L, Peng, J, Guo, H, Yi, C. | 登録日 | 2015-04-18 | 公開日 | 2015-09-23 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Biochemical and Structural Insights into the Mechanism of DNA Recognition by Arabidopsis ETHYLENE INSENSITIVE3. Plos One, 10, 2015
|
|
4ZHJ
| |
4YVQ
| |
4YVO
| |
5B6L
| Structure of Deg protease HhoA from Synechocystis sp. PCC 6803 | 分子名称: | Putative serine protease HhoA, SODIUM ION, UNK-UNK-UNK-UNK-TRP, ... | 著者 | Dong, W, Wang, J, Liu, L. | 登録日 | 2016-05-30 | 公開日 | 2016-09-21 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.801 Å) | 主引用文献 | Crystal structure of the zinc-bound HhoA protease from Synechocystis sp. PCC 6803 Febs Lett., 590, 2016
|
|