8QBH
| AntI in complex with 1-Naphthol | 分子名称: | 1-NAPHTHOL, Photorhabdus luminescens subsp. laumondii TTO1 complete genome segment 15/17 | 著者 | Schmalhofer, M, Vagstad, A.L, Zhou, Q, Bode, H.B, Groll, M. | 登録日 | 2023-08-24 | 公開日 | 2024-03-13 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Polyketide Trimming Shapes Dihydroxynaphthalene-Melanin and Anthraquinone Pigments. Adv Sci, 11, 2024
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7OLQ
| Dioxygenase AsqJ mutant (V72I) in complex with 2 and Tris | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-Methoxydehydrocyclopeptin, BROMIDE ION, ... | 著者 | Auman, D, Mader, S.L, Ecker, F, Dorst, K, Braeuer, A, Widmalm, G, Groll, M, Kaila, V.R.I. | 登録日 | 2021-05-20 | 公開日 | 2022-06-01 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Peroxy Intermediate Drives Carbon Bond Activation in the Dioxygenase AsqJ. J.Am.Chem.Soc., 144, 2022
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8QD3
| Ayg1p in complex with 1,3,6,8-Tetrahydroxynaphthalene | 分子名称: | 1,2-ETHANEDIOL, FLAVIOLIN, Pigment biosynthesis protein yellowish-green 1, ... | 著者 | Schmalhofer, M, Vagstad, A.L, Zhou, Q, Bode, H.B, Groll, M. | 登録日 | 2023-08-28 | 公開日 | 2024-03-13 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Polyketide Trimming Shapes Dihydroxynaphthalene-Melanin and Anthraquinone Pigments. Adv Sci, 11, 2024
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8QBI
| AntI in closed state | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Photorhabdus luminescens subsp. laumondii TTO1 complete genome segment 15/17, ... | 著者 | Schmalhofer, M, Vagstad, A.L, Zhou, Q, Bode, H.B, Groll, M. | 登録日 | 2023-08-24 | 公開日 | 2024-03-13 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Polyketide Trimming Shapes Dihydroxynaphthalene-Melanin and Anthraquinone Pigments. Adv Sci, 11, 2024
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7OLK
| Dioxygenase AsqJ in complex with 2b and Tris | 分子名称: | (3~{Z})-4-methyl-3-(phenylmethylidene)-1~{H}-1,4-benzodiazepine-2,5-dione, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BROMIDE ION, ... | 著者 | Auman, D, Mader, S.L, Ecker, F, Dorst, K, Braeuer, A, Widmalm, G, Groll, M, Kaila, V.R.I. | 登録日 | 2021-05-20 | 公開日 | 2022-06-01 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Peroxy Intermediate Drives Carbon Bond Activation in the Dioxygenase AsqJ. J.Am.Chem.Soc., 144, 2022
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7OLT
| Dioxygenase AsqJ in complex with 2 and Tris | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-Methoxydehydrocyclopeptin, BROMIDE ION, ... | 著者 | Auman, D, Mader, S.L, Ecker, F, Dorst, K, Braeuer, A, Widmalm, G, Groll, M, Kaila, V.R.I. | 登録日 | 2021-05-20 | 公開日 | 2022-06-01 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Peroxy Intermediate Drives Carbon Bond Activation in the Dioxygenase AsqJ. J.Am.Chem.Soc., 144, 2022
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8QD5
| AntI Ser245DHA (PSF) | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Photorhabdus luminescens subsp. laumondii TTO1 complete genome segment 15/17, ... | 著者 | Schmalhofer, M, Vagstad, A.L, Zhou, Q, Bode, H.B, Groll, M. | 登録日 | 2023-08-28 | 公開日 | 2024-03-13 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Polyketide Trimming Shapes Dihydroxynaphthalene-Melanin and Anthraquinone Pigments. Adv Sci, 11, 2024
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8QDA
| Wdyg1p Ser256DHA (PMSF) | 分子名称: | 1,2-ETHANEDIOL, TRIETHYLENE GLYCOL, Yellowish-green 1-like protein | 著者 | Schmalhofer, M, Vagstad, A.L, Zhou, Q, Bode, H.B, Groll, M. | 登録日 | 2023-08-28 | 公開日 | 2024-03-13 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Polyketide Trimming Shapes Dihydroxynaphthalene-Melanin and Anthraquinone Pigments. Adv Sci, 11, 2024
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8QD9
| Wdyg1p in complex with 1,3,6,8-Tetrahydroxynaphthalene | 分子名称: | 1,2-ETHANEDIOL, Yellowish-green 1-like protein, naphthalene-1,3,6,8-tetrol | 著者 | Schmalhofer, M, Vagstad, A.L, Zhou, Q, Bode, H.B, Groll, M. | 登録日 | 2023-08-28 | 公開日 | 2024-03-13 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Polyketide Trimming Shapes Dihydroxynaphthalene-Melanin and Anthraquinone Pigments. Adv Sci, 11, 2024
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5EGP
| Crystal structure of the S-methyltransferase TmtA | 分子名称: | ACETATE ION, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... | 著者 | Duell, E.R, Glaser, M, Antes, I, Groll, M, Huber, E.M. | 登録日 | 2015-10-27 | 公開日 | 2016-02-03 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Sequential Inactivation of Gliotoxin by the S-Methyltransferase TmtA. Acs Chem.Biol., 11, 2016
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8OLL
| Staphylococcus aureus ClpP in complex with the natural product beta-lactone inhibitor Cystargolide A at 2.7 A resolution | 分子名称: | ATP-dependent Clp protease proteolytic subunit, Cystargolide A (bound) | 著者 | Illigmann, A, Vielberg, M.-T, Lakemeyer, M, Wolf, F, Staudt, N, Dema, T, Stange, P, Malik, I, Grond, S, Sieber, S.A, Groll, M, Kaysser, L, Broetz-Oesterhelt, H. | 登録日 | 2023-03-30 | 公開日 | 2023-12-06 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure of Staphylococcus aureus ClpP Bound to the Covalent Active-Site Inhibitor Cystargolide A. Angew.Chem.Int.Ed.Engl., 63, 2024
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8OLR
| Structure of yeast 20S proteasome in complex with the natural product beta-lactone inhibitor Cystargolide A | 分子名称: | CHLORIDE ION, Cystargolide A (bound), MAGNESIUM ION, ... | 著者 | Illigmann, A, Vielberg, M.-T, Lakemeyer, M, Wolf, F, Staudt, N, Dema, T, Stange, P, Malik, I, Grond, S, Sieber, S.A, Groll, M, Kaysser, L, Broetz-Oesterhelt, H. | 登録日 | 2023-03-30 | 公開日 | 2023-12-06 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of Staphylococcus aureus ClpP Bound to the Covalent Active-Site Inhibitor Cystargolide A. Angew.Chem.Int.Ed.Engl., 63, 2024
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4EB3
| Crystal structure of IspH in complex with iso-HMBPP | 分子名称: | 3-(hydroxymethyl)but-3-en-1-yl trihydrogen diphosphate, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, IRON/SULFUR CLUSTER | 著者 | Wang, W, Wang, K, Span, I, Bacher, A, Groll, M, Oldfield, E. | 登録日 | 2012-03-23 | 公開日 | 2013-02-06 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Are free radicals involved in IspH catalysis? An EPR and crystallographic investigation. J.Am.Chem.Soc., 134, 2012
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4FFO
| PylC in complex with phosphorylated D-ornithine | 分子名称: | (2R)-2,5-diaminopentanoyl dihydrogen phosphate, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Quitterer, F, List, A, Beck, P, Bacher, A, Groll, M. | 登録日 | 2012-06-01 | 公開日 | 2012-09-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Biosynthesis of the 22nd genetically encoded amino acid pyrrolysine: structure and reaction mechanism of PylC at 1.5A resolution. J.Mol.Biol., 424, 2012
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4FFP
| PylC in complex with L-lysine-Ne-D-ornithine (cocrystallized with L-lysine and D-ornithine) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, N~6~-D-ornithyl-L-lysine, ... | 著者 | Quitterer, F, List, A, Beck, P, Bacher, A, Groll, M. | 登録日 | 2012-06-01 | 公開日 | 2012-09-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Biosynthesis of the 22nd genetically encoded amino acid pyrrolysine: structure and reaction mechanism of PylC at 1.5A resolution. J.Mol.Biol., 424, 2012
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4FFL
| PylC in complex with L-lysine | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, CARBONATE ION, ... | 著者 | Quitterer, F, List, A, Beck, P, Bacher, A, Groll, M. | 登録日 | 2012-06-01 | 公開日 | 2012-09-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Biosynthesis of the 22nd genetically encoded amino acid pyrrolysine: structure and reaction mechanism of PylC at 1.5A resolution. J.Mol.Biol., 424, 2012
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4FFN
| PylC in complex with D-ornithine and AMPPNP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, D-ORNITHINE, MAGNESIUM ION, ... | 著者 | Quitterer, F, List, A, Beck, P, Bacher, A, Groll, M. | 登録日 | 2012-06-01 | 公開日 | 2012-09-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Biosynthesis of the 22nd genetically encoded amino acid pyrrolysine: structure and reaction mechanism of PylC at 1.5A resolution. J.Mol.Biol., 424, 2012
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4FFM
| PylC in complex with L-lysine-Ne-D-ornithine (cocrystallized with L-lysine-Ne-D-ornithine) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Quitterer, F, List, A, Beck, P, Bacher, A, Groll, M. | 登録日 | 2012-06-01 | 公開日 | 2012-09-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Biosynthesis of the 22nd genetically encoded amino acid pyrrolysine: structure and reaction mechanism of PylC at 1.5A resolution. J.Mol.Biol., 424, 2012
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4FFR
| SeMet-labeled PylC (remote) | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PylC | 著者 | Quitterer, F, List, A, Beck, P, Bacher, A, Groll, M. | 登録日 | 2012-06-01 | 公開日 | 2012-09-19 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Biosynthesis of the 22nd genetically encoded amino acid pyrrolysine: structure and reaction mechanism of PylC at 1.5A resolution. J.Mol.Biol., 424, 2012
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6EK4
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6EL1
| YaxAB pore complex | 分子名称: | YaxA, YaxB | 著者 | Braeuning, B, Bertosin, E, Dietz, H, Groll, M. | 登録日 | 2017-09-27 | 公開日 | 2018-05-16 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (6.1 Å) | 主引用文献 | Structure and mechanism of the two-component alpha-helical pore-forming toxin YaxAB. Nat Commun, 9, 2018
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5JHR
| Yeast 20S proteasome in complex with the peptidic epoxyketone inhibitor 27 | 分子名称: | (2S)-2-azido-N-[(2S)-3-(biphenyl-4-yl)-1-{[(2S)-1-{[(2S,3S,4R)-3,5-dihydroxy-4-methylpentan-2-yl]amino}-1-oxo-3-phenylpropan-2-yl]amino}-1-oxopropan-2-yl]-3-phenylpropanamide (non-preferred name), 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... | 著者 | Huber, E.M, Groll, M. | 登録日 | 2016-04-21 | 公開日 | 2016-08-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure-Based Design of beta 5c Selective Inhibitors of Human Constitutive Proteasomes. J.Med.Chem., 59, 2016
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5FGE
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5JHS
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5FGD
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