4HF2
 
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4HF0
 | | Crystal Structure of Apo IscR | | 分子名称: | HTH-type transcriptional regulator IscR, SULFATE ION | | 著者 | Rajagopalan, S.R, Phillips, K.J. | | 登録日 | 2012-10-04 | | 公開日 | 2013-05-08 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Studies of IscR reveal a unique mechanism for metal-dependent regulation of DNA binding specificity.
Nat.Struct.Mol.Biol., 20, 2013
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7RMW
 | | Crystal structure of B. subtilis PurR bound to ppGpp | | 分子名称: | GUANOSINE-5',3'-TETRAPHOSPHATE, Pur operon repressor | | 著者 | Schumacher, M.A. | | 登録日 | 2021-07-28 | | 公開日 | 2021-12-22 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | The nucleotide messenger (p)ppGpp is an anti-inducer of the purine synthesis transcription regulator PurR in Bacillus.
Nucleic Acids Res., 50, 2022
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4HF1
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3GCT
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3HZI
 | | Structure of mdt protein | | 分子名称: | 5'-D(*DAP*DCP*DTP*DAP*DTP*DCP*DCP*DCP*DCP*DTP*DTP*DAP*DAP*DGP*DGP*DGP*DGP*DAP*DTP*DAP*DG)-3', ADENOSINE-5'-TRIPHOSPHATE, HTH-type transcriptional regulator hipB, ... | | 著者 | Schumacher, M.A. | | 登録日 | 2009-06-23 | | 公開日 | 2009-07-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | | 主引用文献 | Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB.
Science, 323, 2009
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6PFJ
 | | Structure of S. venezuelae RsiG-WhiG-(ci-di-GMP) complex, P64 crystal form | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), AmfC protein, RNA polymerase sigma factor | | 著者 | Schumacher, M.A. | | 登録日 | 2019-06-21 | | 公開日 | 2019-11-13 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | c-di-GMP Arms an Anti-sigma to Control Progression of Multicellular Differentiation in Streptomyces.
Mol.Cell, 77, 2020
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6PFV
 | | Structure of S. venezuelae RisG-WhiG-c-di-GMP complex: orthorhombic crystal form | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), AmfC protein, RNA polymerase sigma factor | | 著者 | Schumacher, M.A. | | 登録日 | 2019-06-22 | | 公開日 | 2019-11-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | c-di-GMP Arms an Anti-sigma to Control Progression of Multicellular Differentiation in Streptomyces.
Mol.Cell, 77, 2020
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3PM1
 | | Structure of QacR E90Q bound to Ethidium | | 分子名称: | ETHIDIUM, HTH-type transcriptional regulator qacR, SULFATE ION | | 著者 | Schumacher, M.A. | | 登録日 | 2010-11-15 | | 公開日 | 2011-07-13 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | A single acidic residue can guide binding site selection but does not govern QacR cationic-drug affinity.
Plos One, 6, 2011
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1BIB
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4YG4
 | | HipB-O1-O1* complex | | 分子名称: | Antitoxin HipB, DNA (28-MER), DNA (5'-D(*AP*TP*AP*TP*CP*CP*CP*CP*TP*TP*AP*AP*GP*GP*GP*GP*AP*TP*AP*A)-3') | | 著者 | Schumacher, M.A. | | 登録日 | 2015-02-25 | | 公開日 | 2015-07-29 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | HipBA-promoter structures reveal the basis of heritable multidrug tolerance.
Nature, 524, 2015
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4YG7
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2HYF
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4YG1
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2GCT
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2HYG
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2G0E
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5TZF
 | | Structure of the BldD CTD(D116A)-(c-di-GMP)2 intermediate, form 1 | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DNA-binding protein | | 著者 | Schumacher, M.A. | | 登録日 | 2016-11-21 | | 公開日 | 2017-04-19 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD2-(c-di-GMP)4 complex.
Nucleic Acids Res., 45, 2017
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5TZG
 | | Structure of the BldD CTD(D116A)-(c-di-GMP)2, form 2 | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DNA-binding protein, ZINC ION | | 著者 | Schumacher, M.A. | | 登録日 | 2016-11-21 | | 公開日 | 2017-04-19 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD2-(c-di-GMP)4 complex.
Nucleic Acids Res., 45, 2017
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5TZD
 | | Structure of the WT S. venezulae BldD-(CTD-c-di-GMP)2 assembly intermediate | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DNA-binding protein | | 著者 | Schumacher, M. | | 登録日 | 2016-11-21 | | 公開日 | 2017-04-19 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.749 Å) | | 主引用文献 | The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD2-(c-di-GMP)4 complex.
Nucleic Acids Res., 45, 2017
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5CRO
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3DNU
 | | structure of MDT protein | | 分子名称: | CHLORIDE ION, PHOSPHATE ION, Protein hipA | | 著者 | schumacher, M.A. | | 登録日 | 2008-07-02 | | 公開日 | 2009-01-27 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB.
Science, 323, 2009
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3FBR
 | | structure of HipA-amppnp-peptide | | 分子名称: | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Serine/threonine-protein kinase toxin HipA, peptide of EF-Tu | | 著者 | Schumacher, M.A. | | 登録日 | 2008-11-19 | | 公開日 | 2009-02-10 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB.
Science, 323, 2009
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3DNT
 | | structures of MDT proteins | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein hipA, ... | | 著者 | Schumacher, M.A. | | 登録日 | 2008-07-02 | | 公開日 | 2009-01-27 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB.
Science, 323, 2009
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3DNV
 | | MDT Protein | | 分子名称: | DNA (5'-D(*DAP*DCP*DTP*DAP*DTP*DCP*DCP*DCP*DCP*DTP*DTP*DAP*DAP*DGP*DGP*DGP*DGP*DAP*DTP*DAP*DG)-3'), HTH-type transcriptional regulator hipB, Protein hipA, ... | | 著者 | schumacher, M.A. | | 登録日 | 2008-07-02 | | 公開日 | 2009-01-27 | | 最終更新日 | 2023-04-05 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB.
Science, 323, 2009
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