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3HJD
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BU of 3hjd by Molmil
X-ray structure of monomeric variant of HNP1
分子名称: Human neutrophil peptide 1
著者Lubkowski, J, Pazgier, M, Lu, W.
登録日2009-05-21
公開日2009-10-13
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献What Dictates the Multifaced Functions of the Human alpha-Defensin HNP?
To be Published
5XGV
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BU of 5xgv by Molmil
The structure of Diels-Alderase PyrE3 in the biosynthetic pathway of pyrroindomycins
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, PyrE3
著者Pan, L, Gong, Y, Guo, Y.
登録日2017-04-18
公開日2018-04-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.099 Å)
主引用文献Structural Insights into a Flavin-Dependent [4 + 2] Cyclase that Catalyzes trans-Decalin Formation in Pyrroindomycin Biosynthesis.
Cell Chem Biol, 25, 2018
4YO8
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BU of 4yo8 by Molmil
Crystal structure of Helicobacter pylori 5'-methylthioadenosine/S-adenosyl homocysteine nucleosidase (MTAN) complexed with (((4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl)(hexyl)amino)methanol
分子名称: Aminodeoxyfutalosine nucleosidase, ZINC ION, {[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl](hexyl)amino}methanol
著者Cameron, S.A, Wang, S, Almo, S.C, Schramm, V.L.
登録日2015-03-11
公開日2015-11-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献New Antibiotic Candidates against Helicobacter pylori.
J.Am.Chem.Soc., 137, 2015
4YNB
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BU of 4ynb by Molmil
Crystal structure of Helicobacter pylori 5'-methylthioadenosine/S-adenosyl homocysteine nucleosidase (MTAN) complexed with pyrazinylthio-DADMe-Immucillin-A
分子名称: (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[(pyrazin-2-ylsulfanyl)methyl]pyrrolidin-3-ol, Aminodeoxyfutalosine nucleosidase, DI(HYDROXYETHYL)ETHER, ...
著者Cameron, S.A, Wang, S, Almo, S.C, Schramm, V.L.
登録日2015-03-09
公開日2015-11-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献New Antibiotic Candidates against Helicobacter pylori.
J.Am.Chem.Soc., 137, 2015
8IJD
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BU of 8ijd by Molmil
Cryo-EM structure of human HCAR2-Gi complex with MK-6892
分子名称: 2-[[2,2-dimethyl-3-[3-(5-oxidanylpyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoyl]amino]cyclohexene-1-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Pan, X, Fang, Y.
登録日2023-02-27
公開日2024-01-03
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Structural insights into ligand recognition and selectivity of the human hydroxycarboxylic acid receptor HCAR2.
Cell Discov, 9, 2023
8IJ3
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BU of 8ij3 by Molmil
Cryo-EM structure of human HCAR2-Gi complex without ligand (apo state)
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Pan, X, Fang, Y.
登録日2023-02-24
公開日2024-01-03
実験手法ELECTRON MICROSCOPY (3.28 Å)
主引用文献Structural insights into ligand recognition and selectivity of the human hydroxycarboxylic acid receptor HCAR2.
Cell Discov, 9, 2023
8IJB
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BU of 8ijb by Molmil
Cryo-EM structure of human HCAR2-Gi complex with acipimox
分子名称: 5-methyl-4-oxidanyl-pyrazin-4-ium-2-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Pan, X, Fang, Y.
登録日2023-02-27
公開日2024-01-03
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Structural insights into ligand recognition and selectivity of the human hydroxycarboxylic acid receptor HCAR2.
Cell Discov, 9, 2023
8IJA
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BU of 8ija by Molmil
Cryo-EM structure of human HCAR2-Gi complex with niacin
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Pan, X, Fang, Y.
登録日2023-02-26
公開日2024-01-03
実験手法ELECTRON MICROSCOPY (2.69 Å)
主引用文献Structural insights into ligand recognition and selectivity of the human hydroxycarboxylic acid receptor HCAR2.
Cell Discov, 9, 2023
7FCQ
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BU of 7fcq by Molmil
Crystallographic structure of neutralizing antibody P14-44 in complex with SARS-CoV-2 spike receptor-binding Domain (RBD)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, P14-44 antibody Fab fragment heavy chain, ...
著者Zheng, P, Jin, T.
登録日2021-07-15
公開日2022-06-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Ultrapotent neutralizing antibodies against SARS-CoV-2 with a high degree of mutation resistance.
J.Clin.Invest., 132, 2022
7FCP
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BU of 7fcp by Molmil
Crystallographic structure of two neutralizing antibodies in complex with SARS-CoV-2 spike receptor-binding Domain (RBD)
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
著者Zheng, P, Jin, T.
登録日2021-07-15
公開日2022-06-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Ultrapotent neutralizing antibodies against SARS-CoV-2 with a high degree of mutation resistance.
J.Clin.Invest., 132, 2022
6JK8
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BU of 6jk8 by Molmil
Cryo-EM structure of the full-length human IGF-1R in complex with insulin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin, ...
著者Zhang, X, Yu, D, Wang, T.
登録日2019-02-27
公開日2020-03-04
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Visualization of Ligand-Bound Ectodomain Assembly in the Full-Length Human IGF-1 Receptor by Cryo-EM Single-Particle Analysis.
Structure, 28, 2020
6MSJ
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BU of 6msj by Molmil
Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
著者Mao, Y.D.
登録日2018-10-16
公開日2018-11-21
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome.
Nature, 565, 2019
6MSG
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BU of 6msg by Molmil
Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
著者Mao, Y.D.
登録日2018-10-16
公開日2018-11-21
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome.
Nature, 565, 2019
6MSE
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BU of 6mse by Molmil
Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
著者Mao, Y.D.
登録日2018-10-16
公開日2018-11-21
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome.
Nature, 565, 2019
6MSB
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BU of 6msb by Molmil
Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
著者Mao, Y.D.
登録日2018-10-16
公開日2018-12-05
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome.
Nature, 565, 2019
6MSK
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BU of 6msk by Molmil
Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
著者Mao, Y.D.
登録日2018-10-16
公開日2018-11-21
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome.
Nature, 565, 2019
6MSH
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BU of 6msh by Molmil
Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
著者Mao, Y.D.
登録日2018-10-16
公開日2018-11-21
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome.
Nature, 565, 2019
5EAK
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BU of 5eak by Molmil
Optimization of Microtubule Affinity Regulating Kinase (MARK) Inhibitors with Improved Physical Properties
分子名称: N-[(1S,2R)-2-aminocyclohexyl]-4-[6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-3-yl]thiophene-2-carboxamide, Serine/threonine-protein kinase MARK2
著者Su, H.P.
登録日2015-10-16
公開日2016-02-17
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Optimization of microtubule affinity regulating kinase (MARK) inhibitors with improved physical properties.
Bioorg.Med.Chem.Lett., 26, 2016
6MSD
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BU of 6msd by Molmil
Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
著者Mao, Y.D.
登録日2018-10-16
公開日2018-12-05
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome.
Nature, 565, 2019
3SLU
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BU of 3slu by Molmil
Crystal structure of NMB0315
分子名称: M23 peptidase domain protein, NICKEL (II) ION
著者Shen, Y, Wang, X, Yang, X, Xu, H.
登録日2011-06-26
公開日2012-02-01
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Crystal structure of outer membrane protein NMB0315 from Neisseria meningitidis.
Plos One, 6, 2011
3STO
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BU of 3sto by Molmil
Serpin from the trematode Schistosoma Haematobium
分子名称: Serine protease inhibitor
著者Granzin, J, Weiergraeber, O.H, Lee, X, Blanton, R.E.
登録日2011-07-11
公開日2012-05-30
最終更新日2013-01-23
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Three-dimensional structure of a schistosome serpin revealing an unusual configuration of the helical subdomain.
Acta Crystallogr.,Sect.D, 68, 2012
6AVL
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BU of 6avl by Molmil
Orthorhombic Trypsin (295 K) in the presence of 50% xylose
分子名称: BENZAMIDINE, CALCIUM ION, Cationic trypsin, ...
著者Juers, D.H.
登録日2017-09-02
公開日2017-09-20
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The impact of cryosolution thermal contraction on proteins and protein crystals: volumes, conformation and order.
Acta Crystallogr D Struct Biol, 74, 2018
6B6R
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BU of 6b6r by Molmil
Orthorhombic trypsin cryocooled to 100 K with 50% mpd as cryoprotectant
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, BENZAMIDINE, CALCIUM ION, ...
著者Juers, D.H.
登録日2017-10-03
公開日2017-11-01
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2.00005865 Å)
主引用文献The impact of cryosolution thermal contraction on proteins and protein crystals: volumes, conformation and order.
Acta Crystallogr D Struct Biol, 74, 2018
6B6Q
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BU of 6b6q by Molmil
Orthorhombic trypsin cryocooled to 100 K with 50% xylose as cryoprotectant
分子名称: BENZAMIDINE, CALCIUM ION, Cationic trypsin, ...
著者Juers, D.H.
登録日2017-10-03
公開日2017-11-01
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.000068 Å)
主引用文献The impact of cryosolution thermal contraction on proteins and protein crystals: volumes, conformation and order.
Acta Crystallogr D Struct Biol, 74, 2018
6B6N
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BU of 6b6n by Molmil
Orthorhombic trypsin (295 K) in the presence of 50% mpd
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, BENZAMIDINE, CALCIUM ION, ...
著者Juers, D.H.
登録日2017-10-03
公開日2017-11-01
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The impact of cryosolution thermal contraction on proteins and protein crystals: volumes, conformation and order.
Acta Crystallogr D Struct Biol, 74, 2018

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