5ZTN
| The crystal structure of human DYRK2 in complex with Curcumin | 分子名称: | (1Z,4Z,6E)-5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-one, Dual specificity tyrosine-phosphorylation-regulated kinase 2 | 著者 | Ji, C.G, Xiao, J.Y. | 登録日 | 2018-05-04 | 公開日 | 2018-07-18 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.496 Å) | 主引用文献 | Ancient drug curcumin impedes 26S proteasome activity by direct inhibition of dual-specificity tyrosine-regulated kinase 2. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5WFY
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6DRT
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6DT1
| Crystal structure of the ligase from bacteriophage T4 complexed with DNA intermediate | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ... | 著者 | Shi, K, Aihara, H. | 登録日 | 2018-06-14 | 公開日 | 2018-09-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | T4 DNA ligase structure reveals a prototypical ATP-dependent ligase with a unique mode of sliding clamp interaction. Nucleic Acids Res., 46, 2018
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9EME
| AL amyloid fibril from the FOR103 light chain | 分子名称: | lambda 3 immunoglobulin light chain fragment, residues 2-116 | 著者 | Pfeiffer, P.B, Karimi-Farsijani, S, Kupfer, N, Schmidt, M, Faendrich, M. | 登録日 | 2024-03-08 | 公開日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | Light chain mutations contribute to defining the fibril morphology in systemic AL amyloidosis. Nat Commun, 15, 2024
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6XC1
| Crystal structure of bacteriophage T4 spackle and lysozyme in orthorhombic form | 分子名称: | 1,2-ETHANEDIOL, ISOPROPYL ALCOHOL, Lysozyme, ... | 著者 | Shi, K, Oakland, J.T, Kurniawan, F, Moeller, N.H, Aihara, H. | 登録日 | 2020-06-07 | 公開日 | 2020-12-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Structural basis of superinfection exclusion by bacteriophage T4 Spackle. Commun Biol, 3, 2020
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8F0V
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8F0Y
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1KGF
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1KGE
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7SPO
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7SPP
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8DIQ
| Tubulin-RB3_SLD-TTL in complex with SB226 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-[2-(ethylamino)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-7-methoxy-3,4-dihydroquinoxalin-2(1H)-one, CALCIUM ION, ... | 著者 | White, S.W, Yun, M. | 登録日 | 2022-06-29 | 公開日 | 2023-01-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.395 Å) | 主引用文献 | SB226, an inhibitor of tubulin polymerization, inhibits paclitaxel-resistant melanoma growth and spontaneous metastasis. Cancer Lett., 555, 2022
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1DDS
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1DDR
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6JMI
| Crystal structure of M.tuberculosis Rv0081 | 分子名称: | SULFATE ION, Uncharacterized HTH-type transcriptional regulator Rv0081 | 著者 | Kumar, A, Phulera, S, Mande, C.S. | 登録日 | 2019-03-11 | 公開日 | 2019-04-10 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.896 Å) | 主引用文献 | Structural basis of hypoxic gene regulation by the Rv0081 transcription factor of Mycobacterium tuberculosis. Febs Lett., 593, 2019
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5NAY
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5NAX
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5NB2
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6XC0
| Crystal structure of bacteriophage T4 spackle and lysozyme in monoclinic form | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ... | 著者 | Shi, K, Oakland, J.T, Kurniawan, F, Moeller, N.H, Aihara, H. | 登録日 | 2020-06-07 | 公開日 | 2020-12-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Structural basis of superinfection exclusion by bacteriophage T4 Spackle. Commun Biol, 3, 2020
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5NAZ
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5NB1
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5NB0
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5K59
| Crystal structure of LukGH from Staphylococcus aureus in complex with a neutralising antibody | 分子名称: | CHLORIDE ION, Fab heavy chain, Fab light chain, ... | 著者 | Welin, M, Logan, D.T, Badarau, A, Mirkina, I, Zauner, G, Dolezilkova, I, Nagy, E. | 登録日 | 2016-05-23 | 公開日 | 2016-08-10 | 最終更新日 | 2018-01-17 | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | 主引用文献 | Context matters: The importance of dimerization-induced conformation of the LukGH leukocidin of Staphylococcus aureus for the generation of neutralizing antibodies. Mabs, 8, 2016
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6P0Y
| Cryptosporidium parvum pyruvate kinase in complex with ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Schormann, N, Chattopadhyay, D. | 登録日 | 2019-05-17 | 公開日 | 2019-08-21 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | An overview of structure, function, and regulation of pyruvate kinases. Protein Sci., 28, 2019
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