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Crystal structure of the haemagglutinin mutant (Gln226Leu, Gly228Ser) from an H10N7 seal influenza virus isolated in Germany
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者	Zhang, J, Xiong, X, Purkiss, A, Walker, P, Gamblin, S, Skehel, J.J.
登録日	2020-01-13
公開日	2020-10-21
最終更新日	2024-01-24
実験手法	X-RAY DIFFRACTION (2.68 Å)
主引用文献	Hemagglutinin Traits Determine Transmission of Avian A/H10N7 Influenza Virus between Mammals. Cell Host Microbe, 28, 2020

6TWS

Crystal structure of the haemagglutinin mutant (Gln226Leu, Gly228Ser) from an H10N7 seal influenza virus isolated in Germany with 2mM EDTA
分子名称:	1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者	Zhang, J, Xiong, X, Purkiss, A, Walker, P, Gamblin, S, Skehel, J.J.
登録日	2020-01-13
公開日	2020-10-21
最終更新日	2024-01-24
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Hemagglutinin Traits Determine Transmission of Avian A/H10N7 Influenza Virus between Mammals. Cell Host Microbe, 28, 2020

3BYZ

2-Amino-1,3-thiazol-4(5H)-ones as Potent and Selective 11-Hydroxysteroid Dehydrogenase Type 1 Inhibitors
分子名称:	(5S)-2-(cyclooctylamino)-5-methyl-5-propyl-1,3-thiazol-4(5H)-one, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者	Zhang, J, Jordan, S.R, Li, V.
登録日	2008-01-16
公開日	2008-02-12
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (2.69 Å)
主引用文献	2-amino-1,3-thiazol-4(5H)-ones as potent and selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: enzyme-ligand co-crystal structure and demonstration of pharmacodynamic effects in C57Bl/6 mice. J.Med.Chem., 51, 2008

8HDK

Structure of the Rat GluN1-GluN2C NMDA receptor in complex with glycine and glutamate (minor class in symmetry)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
著者	Zhang, M, Zhang, J, Guo, F, Li, Y, Zhu, S.
登録日	2022-11-04
公開日	2023-03-29
最終更新日	2023-05-31
実験手法	ELECTRON MICROSCOPY (4.3 Å)
主引用文献	Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits. Nat.Struct.Mol.Biol., 30, 2023

7UPY

An antibody from single human VH-rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者	Zhang, J, Luo, S, Kreutzberger, A, Kirchhausen, T, Chen, B, Haynes, B, Alt, F.
登録日	2022-04-18
公開日	2022-08-10
最終更新日	2024-02-21
実験手法	ELECTRON MICROSCOPY (3.1 Å)
主引用文献	An antibody from single human V H -rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion. Sci Immunol, 7, 2022

7UPX

Three RBD-down state of SARS-CoV-2 D614G spike in complex with the SP1-77 neutralizing antibody Fab fragment (local refinement of the RBD and Fab variable domains)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, SP1-77 Fab heavy chain, SP1-77 Fab light chain, ...
著者	Zhang, J, Luo, S, Kreutzberger, A, Kirchhausen, T, Chen, B, Haynes, B, Alt, F.
登録日	2022-04-18
公開日	2022-08-10
最終更新日	2023-08-23
実験手法	ELECTRON MICROSCOPY (3.2 Å)
主引用文献	An antibody from single human V H -rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion. Sci Immunol, 7, 2022

7UPW

Three RBD-down state of SARS-CoV-2 D614G spike in complex with the SP1-77 neutralizing antibody Fab fragment
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者	Zhang, J, Luo, S, Kreutzberger, A, Kirchhausen, T, Chen, B, Haynes, B, Alt, F.
登録日	2022-04-18
公開日	2022-08-10
最終更新日	2023-08-23
実験手法	ELECTRON MICROSCOPY (2.7 Å)
主引用文献	An antibody from single human V H -rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion. Sci Immunol, 7, 2022

6IRA

Structure of the human GluN1/GluN2A NMDA receptor in the glutamate/glycine-bound state at pH 7.8
分子名称:	Glutamate receptor ionotropic, NMDA 1, NMDA 2A
著者	Zhang, J, Chang, S, Zhang, X, Zhu, S.
登録日	2018-11-12
公開日	2019-01-16
最終更新日	2019-06-05
実験手法	ELECTRON MICROSCOPY (4.5 Å)
主引用文献	Structural Basis of the Proton Sensitivity of Human GluN1-GluN2A NMDA Receptors Cell Rep, 25, 2018

8FDW

Cryo-EM structure of SARS-CoV-2 postfusion spike in membrane
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2, ...
著者	Zhang, J, Shi, W, Cai, Y.F, Zhu, H.S, Peng, H.Q, Voyer, J, Volloch, S.R, Cao, H, Mayer, M.L, Song, K.K, Xu, C, Lu, J.M, Chen, B.
登録日	2022-12-05
公開日	2023-05-10
最終更新日	2023-07-26
実験手法	ELECTRON MICROSCOPY (2.9 Å)
主引用文献	Cryo-EM structure of SARS-CoV-2 postfusion spike in membrane. Nature, 619, 2023

6IRH

Structure of the human GluN1/GluN2A NMDA receptor in the glutamate/glycine-bound state at pH 6.3, Class III
分子名称:	Glutamate receptor ionotropic, NMDA 1, NMDA 2A
著者	Zhang, J, Chang, S, Zhang, X, Zhu, S.
登録日	2018-11-12
公開日	2019-01-16
最終更新日	2019-06-05
実験手法	ELECTRON MICROSCOPY (7.8 Å)
主引用文献	Structural Basis of the Proton Sensitivity of Human GluN1-GluN2A NMDA Receptors Cell Rep, 25, 2018

6IRF

Structure of the human GluN1/GluN2A NMDA receptor in the glutamate/glycine-bound state at pH 6.3, Class I
分子名称:	Glutamate receptor ionotropic, NMDA 1, NMDA 2A
著者	Zhang, J, Chang, S, Zhang, X, Zhu, S.
登録日	2018-11-12
公開日	2019-01-16
最終更新日	2019-06-05
実験手法	ELECTRON MICROSCOPY (5.1 Å)
主引用文献	Structural Basis of the Proton Sensitivity of Human GluN1-GluN2A NMDA Receptors Cell Rep, 25, 2018

8DSG

P411-PFA carbene transferase
分子名称:	1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cytochrome P450-BM3 variant P411-PFA, ...
著者	Maggiolo, A.O, Porter, N.J, Zhang, J, Arnold, F.H.
登録日	2022-07-22
公開日	2023-03-08
最終更新日	2024-05-01
実験手法	X-RAY DIFFRACTION (1.87 Å)
主引用文献	Chemodivergent C(sp 3 )-H and C(sp 2 )-H Cyanomethylation Using Engineered Carbene Transferases. Nat Catal, 6, 2023

6IRG

Structure of the human GluN1/GluN2A NMDA receptor in the glutamate/glycine-bound state at pH 6.3, Class II
分子名称:	Glutamate receptor ionotropic, NMDA 1, NMDA 2A
著者	Zhang, J, Chang, S, Zhang, X, Zhu, S.
登録日	2018-11-12
公開日	2019-01-16
最終更新日	2019-06-05
実験手法	ELECTRON MICROSCOPY (5.5 Å)
主引用文献	Structural Basis of the Proton Sensitivity of Human GluN1-GluN2A NMDA Receptors Cell Rep, 25, 2018

8HTX

Crystal structure of BANP in complex with methylated DNA
分子名称:	DNA (5'-D(CPTPCPTP(5CM)PGPCPGPAPGPAPG)-3'), Protein BANP
著者	Zhang, J, Min, J, Liu, K.
登録日	2022-12-21
公開日	2023-05-24
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Structural insights into DNA recognition by the BEN domain of the transcription factor BANP. J.Biol.Chem., 299, 2023

3H4R

Crystal structure of E. coli RecE exonuclease
分子名称:	Exodeoxyribonuclease 8
著者	Bell, C.E, Zhang, J.
登録日	2009-04-20
公開日	2009-05-26
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Crystal structure of E. coli RecE protein reveals a toroidal tetramer for processing double-stranded DNA breaks. Structure, 17, 2009

7CWE

Human Fructose-1,6-bisphosphatase 1 in APO R-state
分子名称:	Fructose-1,6-bisphosphatase 1, MAGNESIUM ION
著者	Chen, Y, Zhang, J, Li, C, Cao, Y.
登録日	2020-08-28
公開日	2021-09-08
最終更新日	2023-11-29
実験手法	X-RAY DIFFRACTION (3 Å)
主引用文献	Human Fructose-1,6-bisphosphatase 1 in APO R-state To Be Published

8IW5

Crystal structure of liprin-beta H2H3 dimer
分子名称:	CALCIUM ION, Liprin-beta-1
著者	Zhang, J, Chen, S, Wei, Z.
登録日	2023-03-29
公開日	2023-11-08
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	KANK1 shapes focal adhesions by orchestrating protein binding, mechanical force sensing, and phase separation. Cell Rep, 42, 2023

8IW0

Crystal structure of the KANK1/liprin-beta1 complex
分子名称:	Liprin-beta-1,KN motif and ankyrin repeat domain-containing protein 1
著者	Zhang, J, Chen, S, Wei, Z, Yu, C.
登録日	2023-03-29
公開日	2023-11-08
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	KANK1 shapes focal adhesions by orchestrating protein binding, mechanical force sensing, and phase separation. Cell Rep, 42, 2023

3SM4

Crystal Structure of the K131A Mutant of Lambda Exonuclease in Complex with a 5'-Phosphorylated 14-mer/12-mer Duplex and Magnesium
分子名称:	5'-D(TPCPGPGPTPAPCPAPGPTPAPG)-3', 5'-D(PAPGPCPTPAPCPTPGPTPAPCPCPGPA)-3', CHLORIDE ION, ...
著者	Bell, C.E, Zhang, J.
登録日	2011-06-27
公開日	2011-07-20
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (1.88 Å)
主引用文献	Crystal structures of {lambda} exonuclease in complex with DNA suggest an electrostatic ratchet mechanism for processivity. Proc.Natl.Acad.Sci.USA, 108, 2011

3SLP

Crystal Structure of Lambda Exonuclease in Complex with a 12 BP Symmetric DNA Duplex
分子名称:	5'-D(GPCPGPAPCPTPAPGPTPCPGPC)-3', CALCIUM ION, CHLORIDE ION, ...
著者	Bell, C.E, Zhang, J.
登録日	2011-06-24
公開日	2011-07-20
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Crystal structures of {lambda} exonuclease in complex with DNA suggest an electrostatic ratchet mechanism for processivity. Proc.Natl.Acad.Sci.USA, 108, 2011

7YFG

Structure of the Rat GluN1-GluN2C NMDA receptor in complex with glycine and glutamate (major class in asymmetry)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ...
著者	Zhang, M, Zhang, J, Guo, F, Li, Y, Zhu, S.
登録日	2022-07-08
公開日	2023-03-29
最終更新日	2023-05-31
実験手法	ELECTRON MICROSCOPY (3.6 Å)
主引用文献	Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits. Nat.Struct.Mol.Biol., 30, 2023

7YFH

Structure of the Rat GluN1-GluN2C NMDA receptor in complex with glycine, glutamate and (R)-PYD-106
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ...
著者	Zhang, M, Zhang, J, Guo, F, Li, Y, Zhu, S.
登録日	2022-07-08
公開日	2023-03-29
最終更新日	2023-05-31
実験手法	ELECTRON MICROSCOPY (3 Å)
主引用文献	Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits. Nat.Struct.Mol.Biol., 30, 2023

7YFI

Structure of the Rat tri-heteromeric GluN1-GluN2A-GluN2C NMDA receptor in complex with glycine and glutamate
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ...
著者	Zhang, M, Zhang, J, Guo, F, Li, Y, Zhu, S.
登録日	2022-07-08
公開日	2023-03-29
最終更新日	2023-07-26
実験手法	ELECTRON MICROSCOPY (3.3 Å)
主引用文献	Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits. Nat.Struct.Mol.Biol., 30, 2023

6IZ2

Crystal structure of DinB/YfiT protein DR0053 from D. radiodurans R1
分子名称:	ACETATE ION, DinB/YfiT family protein, ZINC ION
著者	Kim, M.-K, Zhang, J, Zhao, L.
登録日	2018-12-18
公開日	2019-05-15
最終更新日	2024-03-27
実験手法	X-RAY DIFFRACTION (2.069 Å)
主引用文献	Crystal structure of the highly radiation-inducible DinB/YfiT superfamily protein DR0053 from Deinococcus radiodurans R1. Biochem.Biophys.Res.Commun., 513, 2019

7X5V

NaVEh Sodium channel, and NaVEh from the coccolithophore Emiliania huxleyi
分子名称:	ion channel, ion channel,GFP-TwinStrep
著者	Jiang, D, Zhang, J.
登録日	2022-03-05
公開日	2022-06-01
最終更新日	2024-06-26
実験手法	ELECTRON MICROSCOPY (2.83 Å)
主引用文献	N-type fast inactivation of a eukaryotic voltage-gated sodium channel. Nat Commun, 13, 2022

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