5T6K
 
 | | Crystal Structure of TgCDPK1 From Toxoplasma Gondii complexed with GW780159X | | 分子名称: | 4-(3-chlorophenyl)-5-(1,5-naphthyridin-2-yl)-1,3-thiazol-2-amine, Calmodulin-domain protein kinase 1, UNKNOWN ATOM OR ION | | 著者 | Jiang, D.Q, Tempel, W, Walker, J.R, El Bakkouri, M, Loppnau, P, Graslund, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Hui, R, Lovato, D.V, Osman, K.T, Structural Genomics Consortium (SGC) | | 登録日 | 2016-09-01 | | 公開日 | 2016-11-02 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structure of CDPK1 from toxoplasma gondii complexed with SGC-1-19
to be published
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5TF2
 | | CRYSTAL STRUCTURE OF THE WD40 DOMAIN OF THE HUMAN PROLACTIN REGULATORY ELEMENT-BINDING PROTEIN | | 分子名称: | Prolactin regulatory element-binding protein, UNKNOWN ATOM OR ION | | 著者 | Walker, J.R, Zhang, Q, Dong, A, Wernimont, A, Li, Y, He, H, Tempel, W, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Chen, Z, Tong, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2016-09-23 | | 公開日 | 2016-11-23 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | CRYSTAL STRUCTURE OF THE WD40 DOMAIN OF THE HUMAN PROLACTIN REGULATORY ELEMENT-BINDING PROTEIN (CASP target)
To be published
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5TEY
 | | Human METTL3-METTL14 complex | | 分子名称: | 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, MAGNESIUM ION, ... | | 著者 | DONG, A, ZENG, H, LI, Y, TEMPEL, W, Seitova, A, Hutchinson, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, BROWN, P.J, WU, H, Structural Genomics Consortium (SGC) | | 登録日 | 2016-09-23 | | 公開日 | 2016-11-23 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Human METTL3-METTL14 complex
to be published
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4E71
 | | Crystal structure of the RHO GTPASE binding domain of Plexin B2 | | 分子名称: | Plexin-B2, SODIUM ION | | 著者 | Guan, X, Wang, H, Tempel, W, Tong, Y, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2012-03-16 | | 公開日 | 2012-03-28 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Crystal structure of the RHO GTPASE binding domain of Plexin B2
to be published
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5UBA
 | | Human RNA Pseudouridylate Synthase Domain Containing 4 | | 分子名称: | CALCIUM ION, CHLORIDE ION, RNA pseudouridylate synthase domain-containing protein 4, ... | | 著者 | DONG, A, ZENG, H, TEMPEL, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, BROWN, P.J, WU, H, Structural Genomics Consortium (SGC) | | 登録日 | 2016-12-20 | | 公開日 | 2017-02-22 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | The Crystal Structure of Human Pseudouridylate Synthase Domain Containing 4. To be published
to be published
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4E74
 | | Crystal structure of the RHO GTPASE BINDING DOMAIN of Plexin A4A | | 分子名称: | Plexin-A4, UNKNOWN ATOM OR ION | | 著者 | Guan, X, Wang, H, Tempel, W, Dong, A, Tong, Y, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2012-03-16 | | 公開日 | 2012-03-28 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Crystal structure of the RHO GTPASE BINDING DOMAIN of Plexin A4A
to be published
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5UBB
 | | Crystal structure of human alpha N-terminal protein methyltransferase 1B | | 分子名称: | Alpha N-terminal protein methyltransferase 1B, S-ADENOSYLMETHIONINE, UNKNOWN ATOM OR ION | | 著者 | Dong, C, Zhu, L, Tempel, W, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2016-12-20 | | 公開日 | 2017-03-22 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | An asparagine/glycine switch governs product specificity of human N-terminal methyltransferase NTMT2.
Commun Biol, 1, 2018
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3LLT
 | | Crystal structure of PF14_0431, kinase domain. | | 分子名称: | ACETATE ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SULFATE ION, ... | | 著者 | Wernimont, A.K, Tempel, W, Lin, Y.H, Loppnau, P, MacKenzie, F, Sullivan, H, Weadge, J, Kozieradzki, I, Cossar, D, Sinesterra, G, Vedadi, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Hui, R, Qiu, W, Hutchinson, A, Structural Genomics Consortium (SGC) | | 登録日 | 2010-01-29 | | 公開日 | 2010-08-04 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of PF14_0431, kinase domain.
TO BE PUBLISHED
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4EDU
 | | The MBT repeats of human SCML2 in a complex with histone H2A peptide | | 分子名称: | Histone H2A.J peptide, Sex comb on midleg-like protein 2 | | 著者 | Nady, N, Amaya, M.F, Tempel, W, Ravichandran, M, Arrowsmith, C.H. | | 登録日 | 2012-03-27 | | 公開日 | 2012-09-19 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | Histone recognition by human malignant brain tumor domains.
J.Mol.Biol., 423, 2012
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4EZA
 | | Crystal structure of the atypical phosphoinositide (aPI) binding domain of IQGAP2 | | 分子名称: | Ras GTPase-activating-like protein IQGAP2 | | 著者 | Van Aalten, D.M.F, Dixon, M.J, Gray, A, Schenning, M, Agacan, M, Leslie, N.R, Downes, C.P, Batty, I.H, Nedyalkova, L, Tempel, W, Tong, Y, Zhong, N, Crombet, L, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2012-05-02 | | 公開日 | 2012-05-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | IQGAP Proteins Reveal an Atypical Phosphoinositide (aPI) Binding Domain with a Pseudo C2 Domain Fold.
J.Biol.Chem., 287, 2012
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5VBD
 | | Crystal structure of a putative UBL domain of USP9X | | 分子名称: | UNKNOWN ATOM OR ION, USP9X | | 著者 | Dong, A, Chern, Y, Hou, F, Li, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2017-03-29 | | 公開日 | 2017-04-26 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal structure of a putative UBL domain of USP9X
to be published
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5UNA
 | | Fragment of 7SK snRNA methylphosphate capping enzyme | | 分子名称: | 7SK snRNA methylphosphate capping enzyme, S-ADENOSYL-L-HOMOCYSTEINE, unidentified peptide section/fragment | | 著者 | Wu, H, Tempel, W, Dombrovski, L, McCarthy, A.A, Loppnau, P, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2017-01-30 | | 公開日 | 2017-03-08 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Fragment of 7SK snRNA methylphosphate capping enzyme
To Be Published
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4F7W
 | | Crystal structure of Klebsiella pneumoniae pantothenate kinase in complex with N-pentylpantothenamide | | 分子名称: | (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-(pentylamino)propyl]butanamide, ADENOSINE-5'-DIPHOSPHATE, Pantothenate kinase, ... | | 著者 | Li, B, Tempel, W, Smil, D, Bolshan, Y, Hong, B.S, Park, H.W, Structural Genomics Consortium (SGC) | | 登録日 | 2012-05-16 | | 公開日 | 2013-04-10 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structures of Klebsiella pneumoniae pantothenate kinase in complex with N-substituted pantothenamides.
Proteins, 81, 2013
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5V9J
 | | Crystal structure of catalytic domain of GLP with MS0105 | | 分子名称: | CHLORIDE ION, DIMETHYL SULFOXIDE, Histone-lysine N-methyltransferase EHMT1, ... | | 著者 | Dong, A, Zeng, H, Liu, J, Xiong, Y, Babault, N, Jin, J, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Wu, H, Brown, P.J, Structural Genomics Consortium (SGC) | | 登録日 | 2017-03-23 | | 公開日 | 2018-03-21 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Crystal structure of catalytic domain of GLP with MS0105
to be published
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4FLA
 | | Crystal structure of human RPRD1B, carboxy-terminal domain | | 分子名称: | Regulation of nuclear pre-mRNA domain-containing protein 1B, UNKNOWN ATOM OR ION | | 著者 | Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Guo, X, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Greenblatt, J.F, Structural Genomics Consortium (SGC) | | 登録日 | 2012-06-14 | | 公開日 | 2012-08-22 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation.
Nat.Struct.Mol.Biol., 21, 2014
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4FLB
 | | CID of human RPRD2 | | 分子名称: | PRASEODYMIUM ION, Regulation of nuclear pre-mRNA domain-containing protein 2, SULFATE ION, ... | | 著者 | Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Guo, X, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Greenblatt, J.F, Structural Genomics Consortium (SGC) | | 登録日 | 2012-06-14 | | 公開日 | 2012-08-15 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | | 主引用文献 | RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation.
Nat.Struct.Mol.Biol., 21, 2014
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5UVM
 | | HIT family hydrolase from Clostridium thermocellum Cth-393 | | 分子名称: | ADENOSINE, Histidine triad (HIT) protein, UNKNOWN ATOM OR ION, ... | | 著者 | Habel, J, Tempel, W, Liu, Z.-J, Rose, J, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | | 登録日 | 2017-02-20 | | 公開日 | 2017-04-05 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | HIT family hydrolase from Clostridium thermocellum Cth-393
To Be Published
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4FL6
 | | Crystal structure of the complex of the 3-MBT repeat domain of L3MBTL3 and UNC1215 | | 分子名称: | Lethal(3)malignant brain tumor-like protein 3, UNKNOWN ATOM OR ION, [2-(phenylamino)benzene-1,4-diyl]bis{[4-(pyrrolidin-1-yl)piperidin-1-yl]methanone} | | 著者 | Zhong, N, Tempel, W, Ravichandran, M, Dong, A, Ingerman, L.A, Graslund, S, Frye, S.V, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Structural Genomics Consortium (SGC) | | 登録日 | 2012-06-14 | | 公開日 | 2012-06-27 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain.
Nat. Chem. Biol., 9, 2013
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4FO9
 | | Crystal structure of the E3 SUMO Ligase PIAS2 | | 分子名称: | E3 SUMO-protein ligase PIAS2, UNKNOWN ATOM OR ION, ZINC ION | | 著者 | Dong, A, Hu, J, Dobrovetsky, E, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2012-06-20 | | 公開日 | 2012-07-18 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Crystal structure of the E3 SUMO Ligase PIAS2
to be published
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4FK7
 | | Crystal structure of Certhrax catalytic domain | | 分子名称: | CHLORIDE ION, N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE, Putative ADP-ribosyltransferase Certhrax, ... | | 著者 | Hong, B.S, Dimov, S, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2012-06-12 | | 公開日 | 2012-09-26 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Certhrax Toxin, an Anthrax-related ADP-ribosyltransferase from Bacillus cereus.
J.Biol.Chem., 287, 2012
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4FMW
 | | Crystal structure of methyltransferase domain of human RNA (guanine-9-) methyltransferase domain containing protein 2 | | 分子名称: | 1,2-ETHANEDIOL, POTASSIUM ION, RNA (guanine-9-)-methyltransferase domain-containing protein 2, ... | | 著者 | Dong, A, Zeng, H, Loppnau, P, Tempel, W, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Wu, H, Structural Genomics Consortium (SGC) | | 登録日 | 2012-06-18 | | 公開日 | 2012-08-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of methyltransferase domain of human RNA (guanine-9-) methyltransferase domain containing protein 2
TO BE PUBLISHED
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5VEI
 | | Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2 | | 分子名称: | Sorbin and SH3 domain-containing protein 2, UNKNOWN ATOM OR ION | | 著者 | Liu, Y, Tempel, W, Huang, H, Gu, J, Liu, K, Sidhu, S.S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2017-04-04 | | 公開日 | 2017-08-02 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | | 主引用文献 | Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2
To be Published
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2F7S
 | | The crystal structure of human Rab27b bound to GDP | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-27B | | 著者 | Wang, J, Ismail, S, Shen, Y, Tempel, W, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Bochkarev, A, Park, H.W, Structural Genomics Consortium (SGC) | | 登録日 | 2005-12-01 | | 公開日 | 2005-12-20 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The crystal structure of human Rab27b
To be Published
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2FOL
 | | Crystal structure of human RAB1A in complex with GDP | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-1A, ... | | 著者 | Wang, J, Tempel, W, Shen, Y, Shen, L, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2006-01-13 | | 公開日 | 2006-01-31 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.631 Å) | | 主引用文献 | Crystal structure of human RAB1A in complex with GDP
To be Published
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2FZF
 | | Hypothetical Protein Pfu-1136390-001 From Pyrococcus furiosus | | 分子名称: | hypothetical protein | | 著者 | Fu, Z.-Q, Liu, Z.-J, Lee, D, Kelley, L, Chen, L, Tempel, W, Shah, N, Horanyi, P, Lee, H.S, Habel, J, Dillard, B.D, Nguyen, D, Chang, S.-H, Zhang, H, Chang, J, Sugar, F.J, Poole, F.L, Jenney Jr, F.E, Adams, M.W.W, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | | 登録日 | 2006-02-09 | | 公開日 | 2006-02-21 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Hypothetical Protein Pfu-1136390-001 From Pyrococcus furiosus
To be published
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