1LCL
| CHARCOT-LEYDEN CRYSTAL PROTEIN | 分子名称: | LYSOPHOSPHOLIPASE | 著者 | Acharya, K.R, Leonidas, D.D. | 登録日 | 1996-01-18 | 公開日 | 1997-01-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of human Charcot-Leyden crystal protein, an eosinophil lysophospholipase, identifies it as a new member of the carbohydrate-binding family of galectins. Structure, 3, 1995
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6UZB
| Anthrax toxin protective antigen channels bound to edema factor | 分子名称: | CALCIUM ION, Calmodulin-sensitive adenylate cyclase, Protective antigen | 著者 | Hardenbrook, N.J, Liu, S, Zhou, K, Zhou, Z.H, Krantz, B.A. | 登録日 | 2019-11-14 | 公開日 | 2020-03-04 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Atomic structures of anthrax toxin protective antigen channels bound to partially unfolded lethal and edema factors. Nat Commun, 11, 2020
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3KRJ
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6UZD
| Anthrax toxin protective antigen channels bound to edema factor | 分子名称: | CALCIUM ION, Calmodulin-sensitive adenylate cyclase, Protective antigen | 著者 | Hardenbrook, N.J, Liu, S, Zhou, K, Zhou, Z.H, Krantz, B.A. | 登録日 | 2019-11-14 | 公開日 | 2020-03-04 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Atomic structures of anthrax toxin protective antigen channels bound to partially unfolded lethal and edema factors. Nat Commun, 11, 2020
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6UZE
| Anthrax toxin protective antigen channels bound to edema factor | 分子名称: | CALCIUM ION, Calmodulin-sensitive adenylate cyclase, Protective antigen | 著者 | Hardenbrook, N.J, Liu, S, Zhou, K, Zhou, Z.H, Krantz, B.A. | 登録日 | 2019-11-15 | 公開日 | 2020-03-04 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Atomic structures of anthrax toxin protective antigen channels bound to partially unfolded lethal and edema factors. Nat Commun, 11, 2020
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3KRL
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6R1L
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4JQH
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8ZU2
| Crystal Structure of Human Myt1 Kinase domain Bounded with compound 8g | 分子名称: | 2-azanyl-5-[2-(1,4-diazepan-1-yl)pyridin-4-yl]-3-(2,6-dimethyl-3-oxidanyl-phenyl)benzamide, GLYCINE, Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase | 著者 | Zhang, Z.M, Zhou, Z.Q. | 登録日 | 2024-06-07 | 公開日 | 2024-09-11 | 最終更新日 | 2024-09-25 | 実験手法 | X-RAY DIFFRACTION (1.79888582 Å) | 主引用文献 | Structure-Based Drug Design of 2-Amino-[1,1'-biphenyl]-3-carboxamide Derivatives as Selective PKMYT1 Inhibitors for the Treatment of CCNE1 -Amplified Breast Cancer. J.Med.Chem., 67, 2024
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8ZTX
| Crystal Structure of Human Myt1 Kinase domain Bounded with compound 6b | 分子名称: | 2-azanyl-3-(2,6-dimethyl-3-oxidanyl-phenyl)-5-pyridin-4-yl-benzamide, Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase | 著者 | Zhang, Z.M, Zhou, Z.Q. | 登録日 | 2024-06-07 | 公開日 | 2024-09-11 | 最終更新日 | 2024-09-25 | 実験手法 | X-RAY DIFFRACTION (1.70033228 Å) | 主引用文献 | Structure-Based Drug Design of 2-Amino-[1,1'-biphenyl]-3-carboxamide Derivatives as Selective PKMYT1 Inhibitors for the Treatment of CCNE1 -Amplified Breast Cancer. J.Med.Chem., 67, 2024
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8ZUD
| Crystal Structure of Human Myt1 Kinase domain Bounded with compound 8f | 分子名称: | 2-azanyl-3-(2,6-dimethyl-3-oxidanyl-phenyl)-5-(2-morpholin-4-ylpyridin-4-yl)benzamide, Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase | 著者 | Zhang, Z.M, Zhou, Z.Q. | 登録日 | 2024-06-08 | 公開日 | 2024-09-11 | 最終更新日 | 2024-09-25 | 実験手法 | X-RAY DIFFRACTION (1.50510085 Å) | 主引用文献 | Structure-Based Drug Design of 2-Amino-[1,1'-biphenyl]-3-carboxamide Derivatives as Selective PKMYT1 Inhibitors for the Treatment of CCNE1 -Amplified Breast Cancer. J.Med.Chem., 67, 2024
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8ZUL
| Crystal Structure of Human Myt1 Kinase domain Bounded with compound 8m | 分子名称: | 2-azanyl-5-[2-[(3~{R})-3-azanylpyrrolidin-1-yl]pyridin-4-yl]-3-(2,6-dimethyl-3-oxidanyl-phenyl)benzamide, Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase | 著者 | Zhang, Z.M, Zhou, Z.Q. | 登録日 | 2024-06-09 | 公開日 | 2024-09-11 | 最終更新日 | 2024-09-25 | 実験手法 | X-RAY DIFFRACTION (1.80026162 Å) | 主引用文献 | Structure-Based Drug Design of 2-Amino-[1,1'-biphenyl]-3-carboxamide Derivatives as Selective PKMYT1 Inhibitors for the Treatment of CCNE1 -Amplified Breast Cancer. J.Med.Chem., 67, 2024
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6K07
| Crystal structure of REV7(R124A) in complex with a Shieldin3 fragment | 分子名称: | Mitotic spindle assembly checkpoint protein MAD2B, SULFATE ION, Shieldin complex subunit 3 | 著者 | Zhang, F, Dai, Y. | 登録日 | 2019-05-05 | 公開日 | 2019-12-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Structural basis for shieldin complex subunit 3-mediated recruitment of the checkpoint protein REV7 during DNA double-strand break repair. J.Biol.Chem., 295, 2020
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6LBM
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6LBI
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2LW6
| Solution structure of an avirulence protein AvrPiz-t from pathogen Magnaportheoryzae | 分子名称: | AvrPiz-t protein | 著者 | Zhang, Z.-M, Zhang, X, Zhou, Z, Hu, H, Liu, M, Zhou, B, Zhou, J. | 登録日 | 2012-07-23 | 公開日 | 2012-09-12 | 最終更新日 | 2024-10-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the Magnaporthe oryzae avirulence protein AvrPiz-t. J.Biomol.Nmr, 55, 2013
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6N7I
| Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (gp4(5)-DNA) | 分子名称: | DNA (25-MER), DNA primase/helicase, MAGNESIUM ION, ... | 著者 | Gao, Y, Cui, Y, Zhou, Z, Yang, W. | 登録日 | 2018-11-27 | 公開日 | 2019-03-06 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structures and operating principles of the replisome. Science, 363, 2019
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6N7T
| Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form III) | 分子名称: | DNA (25-MER), DNA primase/helicase, MAGNESIUM ION, ... | 著者 | Gao, Y, Cui, Y, Zhou, Z, Yang, W. | 登録日 | 2018-11-28 | 公開日 | 2019-03-06 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structures and operating principles of the replisome. Science, 363, 2019
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6N7S
| Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form II) | 分子名称: | DNA (25-MER), DNA primase/helicase, MAGNESIUM ION, ... | 著者 | Gao, Y, Cui, Y, Zhou, Z, Yang, W. | 登録日 | 2018-11-28 | 公開日 | 2019-03-06 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Structures and operating principles of the replisome. Science, 363, 2019
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6N9W
| Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS2) | 分子名称: | DNA primase/helicase, DNA-directed DNA polymerase, MAGNESIUM ION, ... | 著者 | Gao, Y, Cui, Y, Zhou, Z, Yang, W. | 登録日 | 2018-12-04 | 公開日 | 2019-03-06 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structures and operating principles of the replisome. Science, 363, 2019
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6N7N
| Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form I) | 分子名称: | DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA primase/helicase, MAGNESIUM ION, ... | 著者 | Gao, Y, Cui, Y, Zhou, Z, Yang, W. | 登録日 | 2018-11-27 | 公開日 | 2019-03-06 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structures and operating principles of the replisome. Science, 363, 2019
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2JNH
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2KLZ
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2LJ1
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2LJ0
| The third SH3 domain of R85FL | 分子名称: | Sorbin and SH3 domain-containing protein 1 | 著者 | Jiang, Y, Hu, H. | 登録日 | 2011-09-02 | 公開日 | 2012-09-05 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure Basis for the Recognition of Ataxin-7 PRR with R85FL SH3 Domain To be Published
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