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6ZD4
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BU of 6zd4 by Molmil
Crystal structure of YTHDC1 S378A mutant
分子名称: SULFATE ION, YTH domain containing 1
著者Bedi, R.K, Li, Y, Caflisch, A.
登録日2020-06-13
公開日2021-01-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1.
J Chem Theory Comput, 17, 2021
6ZD3
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BU of 6zd3 by Molmil
Crystal structure of YTHDC1 M438A mutant
分子名称: DI(HYDROXYETHYL)ETHER, SULFATE ION, YTH domain containing 1
著者Bedi, R.K, Li, Y, Caflisch, A.
登録日2020-06-13
公開日2021-01-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1.
J Chem Theory Comput, 17, 2021
6ZD5
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BU of 6zd5 by Molmil
Crystal structure of YTHDC1 S378A mutant complex with m6A
分子名称: N-methyladenosine, SULFATE ION, YTH domain containing 1
著者Bedi, R.K, Li, Y, Caflisch, A.
登録日2020-06-13
公開日2021-01-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1.
J Chem Theory Comput, 17, 2021
6ZDA
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BU of 6zda by Molmil
Crystal structure of YTHDC1 M438A mutant complex with m6A
分子名称: N-methyladenosine, SULFATE ION, YTHDC1
著者Bedi, R.K, Li, Y, Caflisch, A.
登録日2020-06-14
公開日2021-01-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1.
J Chem Theory Comput, 17, 2021
6ZD8
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BU of 6zd8 by Molmil
Crystal structure of YTHDC1 T379V mutant
分子名称: SULFATE ION, YTHDC1
著者Bedi, R.K, Li, Y, Caflisch, A.
登録日2020-06-14
公開日2021-01-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1.
J Chem Theory Comput, 17, 2021
3E5M
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BU of 3e5m by Molmil
Crystal structure of the HSCARG Y81A mutant
分子名称: NmrA-like family domain-containing protein 1
著者Li, Y, Meng, G, Dai, X, Luo, M, Zheng, X.
登録日2008-08-14
公開日2009-05-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献NADPH is an allosteric regulator of HSCARG
J.Mol.Biol., 387, 2009
5W2J
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BU of 5w2j by Molmil
Crystal structure of dimeric form of mouse Glutaminase C
分子名称: CHLORIDE ION, Glutaminase kidney isoform, mitochondrial, ...
著者Cerione, R.A, Li, Y.
登録日2017-06-06
公開日2018-10-17
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mechanistic Basis of Glutaminase Activation: A KEY ENZYME THAT PROMOTES GLUTAMINE METABOLISM IN CANCER CELLS.
J. Biol. Chem., 291, 2016
8Y2E
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BU of 8y2e by Molmil
Cryo-EM structure of human dopamine transporter in complex with benztropine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Sodium-dependent dopamine transporter, benztropine
著者Zhao, Y, Li, Y.
登録日2024-01-25
公開日2024-08-14
最終更新日2024-08-28
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献Dopamine reuptake and inhibitory mechanisms in human dopamine transporter.
Nature, 632, 2024
8Y2C
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BU of 8y2c by Molmil
Cryo-EM structure of human dopamine transporter in apo state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Sodium-dependent dopamine transporter
著者Zhao, Y, Li, Y.
登録日2024-01-25
公開日2024-08-14
最終更新日2024-08-28
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Dopamine reuptake and inhibitory mechanisms in human dopamine transporter.
Nature, 632, 2024
8Y2F
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BU of 8y2f by Molmil
Cryo-EM structure of human dopamine transporter in complex with GBR12909
分子名称: 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Sodium-dependent dopamine transporter
著者Zhao, Y, Li, Y.
登録日2024-01-25
公開日2024-08-14
最終更新日2024-08-28
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Dopamine reuptake and inhibitory mechanisms in human dopamine transporter.
Nature, 632, 2024
8Y2G
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BU of 8y2g by Molmil
Cryo-EM structure of human dopamine transporter in complex with methylphenidate
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, SODIUM ION, ...
著者Zhao, Y, Li, Y.
登録日2024-01-25
公開日2024-08-14
最終更新日2024-08-28
実験手法ELECTRON MICROSCOPY (2.83 Å)
主引用文献Dopamine reuptake and inhibitory mechanisms in human dopamine transporter.
Nature, 632, 2024
8Y2D
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BU of 8y2d by Molmil
Cryo-EM structure of human dopamine transporter in complex with dopamine
分子名称: CHLORIDE ION, L-DOPAMINE, SODIUM ION, ...
著者Zhao, Y, Li, Y.
登録日2024-01-25
公開日2024-08-14
最終更新日2024-08-28
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Dopamine reuptake and inhibitory mechanisms in human dopamine transporter.
Nature, 632, 2024
4WSI
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BU of 4wsi by Molmil
Crystal Structure of PALS1/Crb complex
分子名称: MAGUK p55 subfamily member 5, Protein crumbs
著者Wei, Z, Li, Y, Zhang, M.
登録日2014-10-28
公開日2014-11-26
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structure of Crumbs tail in complex with the PALS1 PDZ-SH3-GK tandem reveals a highly specific assembly mechanism for the apical Crumbs complex.
Proc.Natl.Acad.Sci.USA, 111, 2014
8HZW
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BU of 8hzw by Molmil
The NMR structure of noursinH11W peptide
分子名称: noursinH11W
著者Yao, H, Li, Y, Zhang, T, Gao, J, Wang, H.
登録日2023-01-09
公開日2023-05-31
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Discovery and biosynthesis of tricyclic copper-binding ribosomal peptides containing histidine-to-butyrine crosslinks.
Nat Commun, 14, 2023
8Y37
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BU of 8y37 by Molmil
Cryo-EM structure of Staphylococcus aureus (15B196) 50S ribosome in complex with MCX-190.
分子名称: 23S ribosomal RNA, 5S ribosomal RNA, 7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid, ...
著者Li, Y, Lu, G, Li, J, Pei, X, Lin, J.
登録日2024-01-28
公開日2024-07-24
実験手法ELECTRON MICROSCOPY (2.53 Å)
主引用文献Synthetic macrolides overcoming MLS B K-resistant pathogens.
Cell Discov, 10, 2024
8Y39
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BU of 8y39 by Molmil
cryo-EM structure of Staphylococcus aureus(ATCC 29213) 70S ribosome in complex with MCX-190.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 5S ribosomal RNA, ...
著者Li, Y, Lu, G, Li, J, Pei, X, Lin, J.
登録日2024-01-28
公開日2024-07-24
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Synthetic macrolides overcoming MLS B K-resistant pathogens.
Cell Discov, 10, 2024
8Y38
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BU of 8y38 by Molmil
Cryo-EM structure of Staphylococcus aureus 70S ribosome (strain 15B196) in complex with MCX-190.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 5S ribosomal RNA, ...
著者Li, Y, Lu, G, Li, J, Pei, X, Lin, J.
登録日2024-01-28
公開日2024-07-24
実験手法ELECTRON MICROSCOPY (2.58 Å)
主引用文献Synthetic macrolides overcoming MLS B K-resistant pathogens.
Cell Discov, 10, 2024
8Y36
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BU of 8y36 by Molmil
cryo-EM structure of Staphylococcus aureus(ATCC 29213) 50S ribosome in complex with MCX-190.
分子名称: 23S ribosomal RNA, 5S ribosomal RNA, 7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid, ...
著者Li, Y, Lu, G, Li, J, Pei, X, Lin, J.
登録日2024-01-28
公開日2024-07-24
実験手法ELECTRON MICROSCOPY (2.65 Å)
主引用文献Synthetic macrolides overcoming MLS B K-resistant pathogens.
Cell Discov, 10, 2024
8I17
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BU of 8i17 by Molmil
Structural basis for H2A-H2B recognitions by human Spt16
分子名称: CHLORIDE ION, FACT complex subunit SPT16, Histone H2A type 1-B/E, ...
著者Huang, H, Li, Y.
登録日2023-01-12
公開日2023-02-22
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structural basis for H2A-H2B recognitions by human Spt16.
Biochem.Biophys.Res.Commun., 651, 2023
4TMP
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BU of 4tmp by Molmil
Crystal structure of AF9 YEATS bound to H3K9ac peptide
分子名称: 1,2-ETHANEDIOL, ALA-ARG-THR-LYS-GLN-THR-ALA-ARG-ALY-SER-THR, Protein AF-9
著者Li, H, Li, Y, Wang, H, Ren, Y.
登録日2014-06-02
公開日2014-11-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献AF9 YEATS Domain Links Histone Acetylation to DOT1L-Mediated H3K79 Methylation.
Cell, 159, 2014
7P88
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BU of 7p88 by Molmil
Crystal structure of YTHDC1 with compound YLI_DC1_002
分子名称: 2-chloranyl-~{N}-methyl-9~{H}-purin-6-amine, SULFATE ION, YTH domain-containing protein 1
著者Bedi, R.K, Li, Y, Dolbois, A, Caflisch, A.
登録日2021-07-21
公開日2021-10-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure-based design of ligands of the m6A-RNA reader YTHDC1
Eur J Med Chem Rep, 5, 2022
7P8B
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BU of 7p8b by Molmil
Crystal structure of YTHDC1 with compound YLI_DC1_006
分子名称: 9-cyclopropyl-~{N}-methyl-purin-6-amine, SULFATE ION, YTH domain-containing protein 1
著者Bedi, R.K, Li, Y, Dolbois, A, Caflisch, A.
登録日2021-07-21
公開日2021-10-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structure-based design of ligands of the m6A-RNA reader YTHDC1
Eur J Med Chem Rep, 5, 2022
7P8A
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BU of 7p8a by Molmil
Crystal structure of YTHDC1 with compound YLI_DC1_003
分子名称: SULFATE ION, YTH domain-containing protein 1, ~{N},9-dimethylpurin-6-amine
著者Bedi, R.K, Li, Y, Dolbois, A, Caflisch, A.
登録日2021-07-21
公開日2021-10-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure-based design of ligands of the m6A-RNA reader YTHDC1
Eur J Med Chem Rep, 5, 2022
7P87
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BU of 7p87 by Molmil
Crystal structure of YTHDC1 with compound YLI_DC1_001
分子名称: N-methyl-4,5,6,7-tetrahydro-1H-indazole-3-carboxamide, SULFATE ION, YTH domain-containing protein 1
著者Bedi, R.K, Li, Y, Dolbois, A, Caflisch, A.
登録日2021-07-21
公開日2021-10-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structure-based design of ligands of the m6A-RNA reader YTHDC1
Eur J Med Chem Rep, 5, 2022
7P8F
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BU of 7p8f by Molmil
Crystal structure of YTHDC1 with compound YLI_DC1_008
分子名称: SULFATE ION, YTH domain-containing protein 1, ~{N},3-dimethyl-1~{H}-pyrazolo[4,3-d]pyrimidin-7-amine
著者Bedi, R.K, Li, Y, Caflisch, A.
登録日2021-07-21
公開日2021-10-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure-based design of ligands of the m6A-RNA reader YTHDC1
Eur J Med Chem Rep, 5, 2022

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