6ZD4
| |
6ZD3
| Crystal structure of YTHDC1 M438A mutant | 分子名称: | DI(HYDROXYETHYL)ETHER, SULFATE ION, YTH domain containing 1 | 著者 | Bedi, R.K, Li, Y, Caflisch, A. | 登録日 | 2020-06-13 | 公開日 | 2021-01-13 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1. J Chem Theory Comput, 17, 2021
|
|
6ZD5
| |
6ZDA
| |
6ZD8
| |
3E5M
| Crystal structure of the HSCARG Y81A mutant | 分子名称: | NmrA-like family domain-containing protein 1 | 著者 | Li, Y, Meng, G, Dai, X, Luo, M, Zheng, X. | 登録日 | 2008-08-14 | 公開日 | 2009-05-12 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | NADPH is an allosteric regulator of HSCARG J.Mol.Biol., 387, 2009
|
|
5W2J
| |
8Y2E
| |
8Y2C
| |
8Y2F
| |
8Y2G
| |
8Y2D
| |
4WSI
| Crystal Structure of PALS1/Crb complex | 分子名称: | MAGUK p55 subfamily member 5, Protein crumbs | 著者 | Wei, Z, Li, Y, Zhang, M. | 登録日 | 2014-10-28 | 公開日 | 2014-11-26 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structure of Crumbs tail in complex with the PALS1 PDZ-SH3-GK tandem reveals a highly specific assembly mechanism for the apical Crumbs complex. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
8HZW
| The NMR structure of noursinH11W peptide | 分子名称: | noursinH11W | 著者 | Yao, H, Li, Y, Zhang, T, Gao, J, Wang, H. | 登録日 | 2023-01-09 | 公開日 | 2023-05-31 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | Discovery and biosynthesis of tricyclic copper-binding ribosomal peptides containing histidine-to-butyrine crosslinks. Nat Commun, 14, 2023
|
|
8Y37
| Cryo-EM structure of Staphylococcus aureus (15B196) 50S ribosome in complex with MCX-190. | 分子名称: | 23S ribosomal RNA, 5S ribosomal RNA, 7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid, ... | 著者 | Li, Y, Lu, G, Li, J, Pei, X, Lin, J. | 登録日 | 2024-01-28 | 公開日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.53 Å) | 主引用文献 | Synthetic macrolides overcoming MLS B K-resistant pathogens. Cell Discov, 10, 2024
|
|
8Y39
| cryo-EM structure of Staphylococcus aureus(ATCC 29213) 70S ribosome in complex with MCX-190. | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 5S ribosomal RNA, ... | 著者 | Li, Y, Lu, G, Li, J, Pei, X, Lin, J. | 登録日 | 2024-01-28 | 公開日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Synthetic macrolides overcoming MLS B K-resistant pathogens. Cell Discov, 10, 2024
|
|
8Y38
| Cryo-EM structure of Staphylococcus aureus 70S ribosome (strain 15B196) in complex with MCX-190. | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 5S ribosomal RNA, ... | 著者 | Li, Y, Lu, G, Li, J, Pei, X, Lin, J. | 登録日 | 2024-01-28 | 公開日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.58 Å) | 主引用文献 | Synthetic macrolides overcoming MLS B K-resistant pathogens. Cell Discov, 10, 2024
|
|
8Y36
| cryo-EM structure of Staphylococcus aureus(ATCC 29213) 50S ribosome in complex with MCX-190. | 分子名称: | 23S ribosomal RNA, 5S ribosomal RNA, 7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid, ... | 著者 | Li, Y, Lu, G, Li, J, Pei, X, Lin, J. | 登録日 | 2024-01-28 | 公開日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | 主引用文献 | Synthetic macrolides overcoming MLS B K-resistant pathogens. Cell Discov, 10, 2024
|
|
8I17
| |
4TMP
| Crystal structure of AF9 YEATS bound to H3K9ac peptide | 分子名称: | 1,2-ETHANEDIOL, ALA-ARG-THR-LYS-GLN-THR-ALA-ARG-ALY-SER-THR, Protein AF-9 | 著者 | Li, H, Li, Y, Wang, H, Ren, Y. | 登録日 | 2014-06-02 | 公開日 | 2014-11-05 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | AF9 YEATS Domain Links Histone Acetylation to DOT1L-Mediated H3K79 Methylation. Cell, 159, 2014
|
|
7P88
| Crystal structure of YTHDC1 with compound YLI_DC1_002 | 分子名称: | 2-chloranyl-~{N}-methyl-9~{H}-purin-6-amine, SULFATE ION, YTH domain-containing protein 1 | 著者 | Bedi, R.K, Li, Y, Dolbois, A, Caflisch, A. | 登録日 | 2021-07-21 | 公開日 | 2021-10-20 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure-based design of ligands of the m6A-RNA reader YTHDC1 Eur J Med Chem Rep, 5, 2022
|
|
7P8B
| Crystal structure of YTHDC1 with compound YLI_DC1_006 | 分子名称: | 9-cyclopropyl-~{N}-methyl-purin-6-amine, SULFATE ION, YTH domain-containing protein 1 | 著者 | Bedi, R.K, Li, Y, Dolbois, A, Caflisch, A. | 登録日 | 2021-07-21 | 公開日 | 2021-10-20 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Structure-based design of ligands of the m6A-RNA reader YTHDC1 Eur J Med Chem Rep, 5, 2022
|
|
7P8A
| Crystal structure of YTHDC1 with compound YLI_DC1_003 | 分子名称: | SULFATE ION, YTH domain-containing protein 1, ~{N},9-dimethylpurin-6-amine | 著者 | Bedi, R.K, Li, Y, Dolbois, A, Caflisch, A. | 登録日 | 2021-07-21 | 公開日 | 2021-10-20 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure-based design of ligands of the m6A-RNA reader YTHDC1 Eur J Med Chem Rep, 5, 2022
|
|
7P87
| Crystal structure of YTHDC1 with compound YLI_DC1_001 | 分子名称: | N-methyl-4,5,6,7-tetrahydro-1H-indazole-3-carboxamide, SULFATE ION, YTH domain-containing protein 1 | 著者 | Bedi, R.K, Li, Y, Dolbois, A, Caflisch, A. | 登録日 | 2021-07-21 | 公開日 | 2021-10-20 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Structure-based design of ligands of the m6A-RNA reader YTHDC1 Eur J Med Chem Rep, 5, 2022
|
|
7P8F
| Crystal structure of YTHDC1 with compound YLI_DC1_008 | 分子名称: | SULFATE ION, YTH domain-containing protein 1, ~{N},3-dimethyl-1~{H}-pyrazolo[4,3-d]pyrimidin-7-amine | 著者 | Bedi, R.K, Li, Y, Caflisch, A. | 登録日 | 2021-07-21 | 公開日 | 2021-10-20 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure-based design of ligands of the m6A-RNA reader YTHDC1 Eur J Med Chem Rep, 5, 2022
|
|