4USG
 
 | | Crystal structure of PC4 W89Y mutant complex with DNA | | 分子名称: | 5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP *TP*TP*TP*TP*TP*G)-3', ACTIVATED RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR P15 | | 著者 | Zhao, Y, Liu, J. | | 登録日 | 2014-07-08 | | 公開日 | 2015-03-18 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.973 Å) | | 主引用文献 | Substitution of Tryptophan 89 with Tyrosine Switches the DNA Binding Mode of Pc4.
Sci.Rep., 5, 2015
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3LL8
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8HHY
 | | SARS-CoV-2 Delta Spike in complex with IS-9A | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IS-9A Fab heavy chain, ... | | 著者 | Mohapatra, A, Wu, Y.-M. | | 登録日 | 2022-11-17 | | 公開日 | 2023-02-01 | | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | | 主引用文献 | Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2.
Nat Commun, 14, 2023
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8HIP
 | | dsRNA transporter | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Systemic RNA interference defective protein 1, ZINC ION, ... | | 著者 | Jiang, D.H, Zhang, J.T. | | 登録日 | 2022-11-21 | | 公開日 | 2023-11-29 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | | 主引用文献 | Structural insights into double-stranded RNA recognition and transport by SID-1.
Nat.Struct.Mol.Biol., 2024
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8HKE
 | | dsRNA transporter | | 分子名称: | RNA (37-MER), Systemic RNA interference defective protein 1, ZINC ION | | 著者 | Jiang, D.H, Zhang, J.T. | | 登録日 | 2022-11-25 | | 公開日 | 2023-11-29 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | | 主引用文献 | Structural insights into double-stranded RNA recognition and transport by SID-1.
Nat.Struct.Mol.Biol., 2024
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8HP3
 | | Crystal structure of meso-diaminopimelate dehydrogenase from Prevotella timonensis | | 分子名称: | 1,2-ETHANEDIOL, Meso-diaminopimelate D-dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Tan, Y, Song, W. | | 登録日 | 2022-12-11 | | 公開日 | 2023-12-13 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | | 主引用文献 | Rational Design of Meso -Diaminopimelate Dehydrogenase with Enhanced Reductive Amination Activity for Efficient Production of d- p -Hydroxyphenylglycine.
Appl.Environ.Microbiol., 89, 2023
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8HP0
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8IQY
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8IQV
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8IQW
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8IQZ
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8I99
 | | N-carbamoyl-D-amino-acid hydrolase mutant - M4Th3 | | 分子名称: | N-carbamoyl-D-amino-acid hydrolase | | 著者 | Hu, J.M, Ni, Y, Xu, G.C. | | 登録日 | 2023-02-06 | | 公開日 | 2023-03-22 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (3.17 Å) | | 主引用文献 | Engineering the Thermostability of a d-Carbamoylase Based on Ancestral Sequence Reconstruction for the Efficient Synthesis of d-Tryptophan.
J.Agric.Food Chem., 71, 2023
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8IES
 | | Cryo-EM structure of ATP13A2 in the E1P-ADP state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Polyamine-transporting ATPase 13A2, ... | | 著者 | Liu, Z.M, Mu, J.Q, Xue, C.Y. | | 登録日 | 2023-02-15 | | 公開日 | 2023-12-20 | | 実験手法 | ELECTRON MICROSCOPY (3.73 Å) | | 主引用文献 | Conformational cycle of human polyamine transporter ATP13A2.
Nat Commun, 14, 2023
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8IEM
 | | Cryo-EM structure of ATP13A2 in the E2P state | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Polyamine-transporting ATPase 13A2, ... | | 著者 | Liu, Z.M, Mu, J.Q, Xue, C.Y. | | 登録日 | 2023-02-15 | | 公開日 | 2023-12-20 | | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | | 主引用文献 | Conformational cycle of human polyamine transporter ATP13A2.
Nat Commun, 14, 2023
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8IEN
 | | Cryo-EM structure of ATP13A2 in the E2-Pi state | | 分子名称: | MAGNESIUM ION, Polyamine-transporting ATPase 13A2, SPERMINE, ... | | 著者 | Liu, Z.M, Mu, J.Q, Xue, C.Y. | | 登録日 | 2023-02-15 | | 公開日 | 2023-12-20 | | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | | 主引用文献 | Conformational cycle of human polyamine transporter ATP13A2.
Nat Commun, 14, 2023
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8IER
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8IEO
 | | Cryo-EM structure of ATP13A2 in the nominal E1P state | | 分子名称: | MAGNESIUM ION, Polyamine-transporting ATPase 13A2, SPERMINE, ... | | 著者 | Liu, Z.M, Mu, J.Q, Xue, C.Y. | | 登録日 | 2023-02-15 | | 公開日 | 2023-12-20 | | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | | 主引用文献 | Conformational cycle of human polyamine transporter ATP13A2.
Nat Commun, 14, 2023
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8IEL
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8IEK
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8IR0
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8IQX
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8J1F
 | | GSK101 bound state of mTRPV4 | | 分子名称: | N-[(2S)-1-{4-[N-(2,4-dichlorobenzene-1-sulfonyl)-L-seryl]piperazin-1-yl}-4-methyl-1-oxopentan-2-yl]-1-benzothiophene-2-carboxamide, Transient receptor potential cation channel subfamily V member 4 | | 著者 | Zhen, W.X, Yang, F. | | 登録日 | 2023-04-12 | | 公開日 | 2023-08-09 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | | 主引用文献 | Structural basis of ligand activation and inhibition in a mammalian TRPV4 ion channel.
Cell Discov, 9, 2023
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8J1H
 | | Agonist1 and Ruthenium Red bound state of mTRPV4 | | 分子名称: | 8-fluoranyl-3-[4-(4-fluoranylphenoxy)phenyl]-2-(4-methylpiperazin-1-yl)quinazolin-4-one, Transient receptor potential cation channel subfamily V member 4 | | 著者 | Zhen, W.X, Yang, F. | | 登録日 | 2023-04-12 | | 公開日 | 2023-08-09 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.88 Å) | | 主引用文献 | Structural basis of ligand activation and inhibition in a mammalian TRPV4 ion channel.
Cell Discov, 9, 2023
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8J1D
 | | Cryo-EM structure of apo state mTRPV4 | | 分子名称: | Transient receptor potential cation channel subfamily V member 4 | | 著者 | Zhen, W.X, Yang, F. | | 登録日 | 2023-04-12 | | 公開日 | 2023-08-09 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | | 主引用文献 | Structural basis of ligand activation and inhibition in a mammalian TRPV4 ion channel.
Cell Discov, 9, 2023
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8J1B
 | | GSK101 and Ruthenium Red bound state of mTRPV4 | | 分子名称: | N-[(2S)-1-{4-[N-(2,4-dichlorobenzene-1-sulfonyl)-L-seryl]piperazin-1-yl}-4-methyl-1-oxopentan-2-yl]-1-benzothiophene-2-carboxamide, Transient receptor potential cation channel subfamily V member 4, ruthenium(6+) azanide pentaamino(oxido)ruthenium (1/4/2) | | 著者 | Zhen, W.X, Yang, F. | | 登録日 | 2023-04-12 | | 公開日 | 2023-08-09 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | | 主引用文献 | Structural basis of ligand activation and inhibition in a mammalian TRPV4 ion channel.
Cell Discov, 9, 2023
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