2Q6F
 
 | | Crystal structure of infectious bronchitis virus (IBV) main protease in complex with a Michael acceptor inhibitor N3 | | 分子名称: | Infectious bronchitis virus (IBV) main protease, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE | | 著者 | Xue, X.Y, Yang, H.T, Xue, F, Bartlam, M, Rao, Z.H. | | 登録日 | 2007-06-05 | | 公開日 | 2008-02-12 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structures of two coronavirus main proteases: implications for substrate binding and antiviral drug design.
J.Virol., 82, 2008
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2Q6D
 | | Crystal structure of infectious bronchitis virus (IBV) main protease | | 分子名称: | Infectious bronchitis virus (IBV) main protease | | 著者 | Xue, X.Y, Yang, H.T, Xue, F, Bartlam, M, Rao, Z.H. | | 登録日 | 2007-06-04 | | 公開日 | 2008-02-12 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structures of two coronavirus main proteases: implications for substrate binding and antiviral drug design.
J.Virol., 82, 2008
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7JPT
 | | Structure of an endocytic receptor | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte antigen 75, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Gully, B.S, Rossjohn, J, Berry, R. | | 登録日 | 2020-08-09 | | 公開日 | 2020-12-09 | | 最終更新日 | 2021-07-14 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | The cryo-EM structure of the endocytic receptor DEC-205.
J.Biol.Chem., 296, 2020
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2Q6G
 | | Crystal structure of SARS-CoV main protease H41A mutant in complex with an N-terminal substrate | | 分子名称: | Polypeptide chain, severe acute respiratory syndrome coronavirus (SARS-CoV) | | 著者 | Xue, X.Y, Yang, H.T, Xue, F, Bartlam, M, Rao, Z.H. | | 登録日 | 2007-06-05 | | 公開日 | 2008-02-12 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structures of two coronavirus main proteases: implications for substrate binding and antiviral drug design.
J.Virol., 82, 2008
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6A8N
 | | The crystal structure of muPAin-1-IG-2 in complex with muPA-SPD at pH8.5 | | 分子名称: | CYS-PRO-ALA-TYR-SER-ARG-TYR-ILE-GLY-CYS, Urokinase-type plasminogen activator B | | 著者 | Wang, D, Yang, Y.S, Jiang, L.G, Huang, M.D, Li, J.Y, Andreasen, P.A, Xu, P, Chen, Z. | | 登録日 | 2018-07-09 | | 公開日 | 2019-02-20 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.489 Å) | | 主引用文献 | Suppression of Tumor Growth and Metastases by Targeted Intervention in Urokinase Activity with Cyclic Peptides.
J.Med.Chem., 62, 2019
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6AKY
 | | The Crystal structure of Human Chemokine Receptor CCR5 in complex with compound 34 | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4,4-difluoro-N-[(1S)-3-{(3-exo)-3-[3-methyl-5-(propan-2-yl)-4H-1,2,4-triazol-4-yl]-8-azabicyclo[3.2.1]octan-8-yl}-1-(thiophen-3-yl)propyl]cyclohexane-1-carboxamide, C-C chemokine receptor type 5,Rubredoxin,C-C chemokine receptor type 5, ... | | 著者 | Zhu, Y, Zhao, Q, Wu, B. | | 登録日 | 2018-09-04 | | 公開日 | 2018-10-24 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure-Based Design of 1-Heteroaryl-1,3-propanediamine Derivatives as a Novel Series of CC-Chemokine Receptor 5 Antagonists.
J. Med. Chem., 61, 2018
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6IVU
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6IVS
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6JMU
 | | Crystal structure of GIT1/Paxillin complex | | 分子名称: | ARF GTPase-activating protein GIT1, Paxillin | | 著者 | Zhu, J, Lin, L, Xia, Y, Zhang, R, Zhang, M. | | 登録日 | 2019-03-13 | | 公開日 | 2020-05-20 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | GIT/PIX Condensates Are Modular and Ideal for Distinct Compartmentalized Cell Signaling.
Mol.Cell, 79, 2020
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1FHT
 | | RNA-BINDING DOMAIN OF THE U1A SPLICEOSOMAL PROTEIN U1A117, NMR, 43 STRUCTURES | | 分子名称: | U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A | | 著者 | Allain, F.H.-T, Gubser, C.C, Howe, P.W.A, Nagai, K, Neuhaus, D, Varani, G. | | 登録日 | 1996-02-21 | | 公開日 | 1996-07-11 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the N-terminal RNP domain of U1A protein: the role of C-terminal residues in structure stability and RNA binding.
J.Mol.Biol., 257, 1996
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5Z08
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5WWT
 | | Crystal structure of human NSun6/tRNA | | 分子名称: | Putative methyltransferase NSUN6, tRNA | | 著者 | Liu, R.J, Long, T, Wang, E.D. | | 登録日 | 2017-01-04 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.197 Å) | | 主引用文献 | Structural basis for substrate binding and catalytic mechanism of a human RNA:m5C methyltransferase NSun6
Nucleic Acids Res., 45, 2017
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5WWS
 | | Crystal structure of human NSun6/tRNA/SAM | | 分子名称: | Putative methyltransferase NSUN6, S-ADENOSYLMETHIONINE, tRNA | | 著者 | Liu, R.J, Long, T, Wang, E.D. | | 登録日 | 2017-01-04 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.247 Å) | | 主引用文献 | Structural basis for substrate binding and catalytic mechanism of a human RNA:m5C methyltransferase NSun6
Nucleic Acids Res., 45, 2017
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5Z07
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6KKT
 | | human KCC1 structure determined in KCl and lipid nanodisc | | 分子名称: | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | 著者 | Liu, S, Chang, S, Ye, S, Bai, X, Guo, J. | | 登録日 | 2019-07-27 | | 公開日 | 2019-10-23 | | 最終更新日 | 2020-08-12 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Cryo-EM structures of the human cation-chloride cotransporter KCC1.
Science, 366, 2019
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6KKR
 | | human KCC1 structure determined in KCl and detergent GDN | | 分子名称: | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | 著者 | Liu, S, Chang, S, Ye, S, Bai, X, Guo, J. | | 登録日 | 2019-07-27 | | 公開日 | 2019-10-23 | | 最終更新日 | 2020-08-12 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Cryo-EM structures of the human cation-chloride cotransporter KCC1.
Science, 366, 2019
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6HLF
 | | X-ray structure of Lactobacillus brevis alcohol dehydrogenase mutant - K32A | | 分子名称: | MAGNESIUM ION, MANGANESE (II) ION, R-specific alcohol dehydrogenase | | 著者 | Hermann, J, Nowotny, P, Schneider, S, Hekmat, D, Weuster-Botz, D. | | 登録日 | 2018-09-11 | | 公開日 | 2018-12-12 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Rational Crystal Contact Engineering of Lactobacillus brevis Alcohol Dehydrogenase To Promote Technical Protein Crystallization
Cryst.Growth Des., 2019
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6K9K
 | | Monomeric human ATM (Ataxia telangiectasia mutated) kinase | | 分子名称: | Serine-protein kinase ATM | | 著者 | Xiao, J, Liu, M, Qi, Y, Yuriy, C, Zhang, P, Xu, Y. | | 登録日 | 2019-06-16 | | 公開日 | 2019-12-25 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (7.82 Å) | | 主引用文献 | Structural insights into the activation of ATM kinase.
Cell Res., 29, 2019
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6KKU
 | | human KCC1 structure determined in NaCl and GDN | | 分子名称: | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | 著者 | Liu, S, Chang, S, Ye, S, Bai, X, Guo, J. | | 登録日 | 2019-07-27 | | 公開日 | 2019-10-23 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM structures of the human cation-chloride cotransporter KCC1.
Science, 366, 2019
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5WWQ
 | | Crystal structure of human NSun6 | | 分子名称: | Putative methyltransferase NSUN6 | | 著者 | Liu, R.J, Long, T, Wang, E.D. | | 登録日 | 2017-01-04 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.815 Å) | | 主引用文献 | Structural basis for substrate binding and catalytic mechanism of a human RNA:m5C methyltransferase NSun6
Nucleic Acids Res., 45, 2017
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7WVP
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7WVQ
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5WWR
 | | Crystal structure of human NSun6/tRNA/SFG | | 分子名称: | Putative methyltransferase NSUN6, SINEFUNGIN, tRNA | | 著者 | Liu, R.J, Long, T, Wang, E.D. | | 登録日 | 2017-01-04 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.096 Å) | | 主引用文献 | Structural basis for substrate binding and catalytic mechanism of a human RNA:m5C methyltransferase NSun6
Nucleic Acids Res., 45, 2017
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6KOR
 | | Crystal structure of the RRM domain of SYNCRIP | | 分子名称: | Heterogeneous nuclear ribonucleoprotein Q | | 著者 | Chen, Y, Chan, J, Chen, W, Jobichen, C. | | 登録日 | 2019-08-12 | | 公開日 | 2020-01-22 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.602 Å) | | 主引用文献 | SYNCRIP, a new player in pri-let-7a processing.
Rna, 26, 2020
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7VEZ
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