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9B2C
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BU of 9b2c by Molmil
Structure of the Porcine deltacoronavirus (PDCoV) receptor-binding domain bound to the PD33 antibody Fab fragment and the Kappa light chain nanobody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Kappa light chain nanobody, PD33 Fab heavy chain, ...
著者Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
登録日2024-03-14
公開日2024-11-13
最終更新日2024-12-18
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Isolation and escape mapping of broadly neutralizing antibodies against emerging delta-coronaviruses.
Immunity, 57, 2024
4Q12
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BU of 4q12 by Molmil
Crystal structure of a putative uncharacterized protein Rv3404c and likely sugar N-formyltransferase from Mycobacterium tuberculosis bound to uridine diphosphate
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, URIDINE-5'-DIPHOSPHATE, ...
著者Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2014-04-02
公開日2014-04-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystal structure of a putative uncharacterized protein Rv3404c and likely sugar N-formyltransferase from Mycobacterium tuberculosis
To be Published
4PY3
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BU of 4py3 by Molmil
Crystal Structure of the N-terminal FIC domain of Bep8 protein (VirB-translocated Bartonella effector protein) from Bartonella sp. 1-1C
分子名称: 1,2-ETHANEDIOL, Bartonella effector protein (Bep) substrate of VirB T4SS
著者Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2014-03-25
公開日2015-06-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Evolutionary Diversification of Host-Targeted Bartonella Effectors Proteins Derived from a Conserved FicTA Toxin-Antitoxin Module.
Microorganisms, 9, 2021
4F4F
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BU of 4f4f by Molmil
X-Ray crystal structure of PLP bound Threonine synthase from Brucella melitensis
分子名称: PYRIDOXAL-5'-PHOSPHATE, Threonine synthase
著者Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-05-10
公開日2012-06-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献X-Ray crystal structure of PLP bound Threonine synthase from Brucella melitensis
TO BE PUBLISHED
9C6O
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BU of 9c6o by Molmil
Merbecovirus MOW15-22 Spike glycoprotein RBD bound to the P. davyi ACE2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MOW15-22 RBD, ...
著者Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2024-06-07
公開日2025-03-05
最終更新日2025-04-02
実験手法ELECTRON MICROSCOPY (2.77 Å)
主引用文献Multiple independent acquisitions of ACE2 usage in MERS-related coronaviruses.
Cell, 188, 2025
9DAK
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BU of 9dak by Molmil
Merbecovirus PnNL2018B Spike glycoprotein RBD bound to the P. Nathusii ACE2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2024-08-22
公開日2025-02-19
最終更新日2025-04-02
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Multiple independent acquisitions of ACE2 usage in MERS-related coronaviruses.
Cell, 188, 2025
9E0I
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BU of 9e0i by Molmil
Structure of the HKU5-19s RBD bound to the Bos taurus ACE2 receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
著者Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
登録日2024-10-18
公開日2025-02-19
最終更新日2025-05-28
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Molecular basis of convergent evolution of ACE2 receptor utilization among HKU5 coronaviruses.
Cell, 188, 2025
2MJ3
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BU of 2mj3 by Molmil
Backbone 1H, 13C, and 15N Chemical Shift Assignments and structure of Iron-sulfur cluster binding protein from Ehrlichia chaffeensis
分子名称: Iron-sulfur cluster binding protein
著者Barnwal, R, Varani, G, Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2013-12-23
公開日2014-01-15
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Backbone 1H, 13C, and 15N Chemical Shift Assignments and structure of Iron-sulfur cluster binding protein from Ehrlichia chaffeensis
To be Published
6C0E
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BU of 6c0e by Molmil
Crystal Structure of Isocitrate Dehydrogenase from Legionella pneumophila with bound NADPH with an alpha-ketoglutarate adduct
分子名称: (3~{S})-3-[(4~{S})-3-aminocarbonyl-1-[(2~{R},3~{R},4~{S},5~{R})-5-[[[[(2~{R},3~{R},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3-oxidanyl-4-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-3,4-bis(oxidanyl)oxolan-2-yl]-4~{H}-pyridin-4-yl]-2-oxidanylidene-pentanedioic acid, CHLORIDE ION, GLYCINE, ...
著者Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2017-12-29
公開日2018-02-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of Isocitrate Dehydrogenase from Legionella pneumophila with bound NADPH with an ??-ketoglutarate adduct
to be published
8VYE
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BU of 8vye by Molmil
SARS-CoV-2 S (C.37 Lambda variant) plus S309, S2L20, and S2X303 Fabs
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, S2L20 Heavy Chain, S2L20 Light Chain, ...
著者McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2024-02-08
公開日2024-03-27
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Quantifying how single dose Ad26.COV2.S vaccine efficacy depends on Spike sequence features.
Nat Commun, 15, 2024
8VYF
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BU of 8vyf by Molmil
SARS-CoV-2 S NTD (C.37 Lambda variant) plus S2L20 and S2X303 Fabs, local refinement
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2L20 Heavy Chain, ...
著者McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2024-02-08
公開日2024-03-27
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Quantifying how single dose Ad26.COV2.S vaccine efficacy depends on Spike sequence features.
Nat Commun, 15, 2024
8W22
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BU of 8w22 by Molmil
Umb1 umbrella toxin particle (local refinement of UmbB1 bound ALF of UmbC1 and UmbA1)
分子名称: Intein C-terminal splicing domain-containing protein, Secreted esterase, Secreted protein
著者Park, Y.J, Zhao, Q, Seattle Structural Genomics Center for Infectious Disease (SSGCID), DiMaio, F, Mougous, J.D, Veesler, D.
登録日2024-02-19
公開日2024-04-17
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Streptomyces umbrella toxin particles block hyphal growth of competing species.
Nature, 629, 2024
8W20
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BU of 8w20 by Molmil
Umb1 umbrella toxin particle
分子名称: Intein C-terminal splicing domain-containing protein, Secreted esterase, Secreted protein
著者Park, Y.J, Zhao, Q, Seattle Structural Genomics Center for Infectious Disease (SSGCID), DiMaio, F, Mougous, J.D, Veesler, D.
登録日2024-02-19
公開日2024-04-17
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Streptomyces umbrella toxin particles block hyphal growth of competing species.
Nature, 629, 2024
8VWP
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BU of 8vwp by Molmil
Langya Virus attachment (G) glycoprotein with K85L/L86K mutation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Langya virus attachment (G) protein
著者Gibson, C.G, McCallum, M.M, Veesler, D.V, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2024-02-02
公開日2024-05-01
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献Structure and design of Langya virus glycoprotein antigens.
Proc.Natl.Acad.Sci.USA, 121, 2024
8VYG
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BU of 8vyg by Molmil
SARS-CoV-2 S RBD (C.37 Lambda variant) plus S309 Fab, local refinement
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, S309 Heavy Chain, S309 Light Chain, ...
著者McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2024-02-08
公開日2024-03-27
最終更新日2025-01-08
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Quantifying how single dose Ad26.COV2.S vaccine efficacy depends on Spike sequence features.
Nat Commun, 15, 2024
9DGO
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BU of 9dgo by Molmil
Designed miniproteins potently inhibit and protect against MERS-CoV. Crystal structure of MERS-CoV S RBD in complex with miniprotein cb3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Designed miniprotein cb_3, ...
著者Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2024-09-03
公開日2025-06-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Designed miniproteins potently inhibit and protect against MERS-CoV.
Cell Rep, 44, 2025
4EFI
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BU of 4efi by Molmil
Crystal Structure of 3-oxoacyl-(Acyl-carrier protein) Synthase from Burkholderia Xenovorans LB400
分子名称: 3-oxoacyl-(Acyl-carrier protein) synthase, CHLORIDE ION, FORMIC ACID, ...
著者Seattle Structural Genomics Center for Infectious Disease, Craig, T.K, Abendroth, J, Staker, B, Stewart, L, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-03-29
公開日2012-04-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Combining functional and structural genomics to sample the essential Burkholderia structome.
Plos One, 8, 2013
6E54
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BU of 6e54 by Molmil
Crystal structure of LpxC from Pseudomonas aeruginosa in complex with ligand PT802
分子名称: (2R)-4-{4-[4-(benzyloxy)-2-fluorophenyl]-2-oxopyridin-1(2H)-yl}-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide, (2S)-4-{4-[4-(benzyloxy)-2-fluorophenyl]-2-oxopyridin-1(2H)-yl}-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide, CALCIUM ION, ...
著者Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2018-07-19
公開日2019-06-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of LpxC from Pseudomonas aeruginosa in complex with ligand PT802
to be published
8U29
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BU of 8u29 by Molmil
Prefusion structure of the PRD-0038 spike glycoprotein ectodomain trimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PRD-0038 Spike glycoprotein, ...
著者Lee, J, Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2023-09-05
公開日2023-12-06
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus.
Cell Host Microbe, 31, 2023
8U0T
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BU of 8u0t by Molmil
PRD-0038 RBD bound to Rhinolophus alcyone ACE2 (local refinement)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, PRD-0038, ...
著者Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2023-08-29
公開日2023-12-06
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus.
Cell Host Microbe, 31, 2023
4PZU
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BU of 4pzu by Molmil
Crystal structure of a putative uncharacterize protein Rv3404c and likely sugar N-formyltransferase from Mycobacterium tuberculosis
分子名称: 1,2-ETHANEDIOL, Uncharacterized protein Rv3404c/MT3512
著者Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2014-03-31
公開日2014-04-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of a putative uncharacterize protein Rv3404c and likely sugar N-formyltransferase from Mycobacterium tuberculosis
TO BE PUBLISHED
4QTP
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BU of 4qtp by Molmil
Crystal Structure of an Anti-sigma Factor Antagonist from Mycobacterium paratuberculosis
分子名称: 1,2-ETHANEDIOL, Anti-sigma factor antagonist, CITRIC ACID, ...
著者Dranow, D.M, Clifton, M.C, Edwards, T.E, Lorimer, D, Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2014-07-08
公開日2014-07-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of an Anti-sigma Factor Antagonist from Mycobacterium paratuberculosis
TO BE PUBLISHED
6BLA
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BU of 6bla by Molmil
Structure of AMM01 Fab, an anti EBV gH/gL neutralizing antibody
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, AMM01 Fab Heavy chain, ...
著者Pancera, M, Weidle, C, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2017-11-09
公開日2018-04-25
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献An Antibody Targeting the Fusion Machinery Neutralizes Dual-Tropic Infection and Defines a Site of Vulnerability on Epstein-Barr Virus.
Immunity, 48, 2018
3CEZ
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BU of 3cez by Molmil
Crystal structure of methionine-R-sulfoxide reductase from Burkholderia pseudomallei
分子名称: ACETIC ACID, Methionine-R-sulfoxide reductase, ZINC ION
著者Staker, B, Napuli, A, Nakazawa, S.H, Castaneda, L, Alkafeef, S, Vanvoorhis, W, Stewart, L, Myler, P, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2008-02-29
公開日2008-03-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Methionine-R-sulfoxide reductase from Burkholderia pseudomallei.
To be Published
8SOY
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BU of 8soy by Molmil
Cryo-EM structure of Enoyl-CoA hydratase from Mycobacterium smegmatis
分子名称: Enoyl-CoA hydratase EchA21
著者Shek, R, Quispe, J, Staker, B, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2023-04-30
公開日2023-05-10
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献Cryo-EM structure of Enoyl-CoA hydratase from Mycobacterium smegmatis
To Be Published

238582

件を2025-07-09に公開中

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