5ZL9
 
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5ZDN
 | | The complex structure of FomD with CDP | | 分子名称: | CYTIDINE-5'-DIPHOSPHATE, FomD, GLYCEROL, ... | | 著者 | Sato, S, Miyanaga, A, Kudo, F, Eguchi, T. | | 登録日 | 2018-02-23 | | 公開日 | 2018-07-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Biochemical and Structural Analysis of FomD That Catalyzes the Hydrolysis of Cytidylyl ( S)-2-Hydroxypropylphosphonate in Fosfomycin Biosynthesis.
Biochemistry, 57, 2018
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5ZDR
 | | Crystal structure of cyanide-insensitive alternative oxidase from Trypanosoma brucei with ascofuranone derivative | | 分子名称: | 3-chloro-4,6-dihydroxy-5-[(2E,6E,8S)-8-hydroxy-3,7-dimethylnona-2,6-dien-1-yl]-2-methylbenzaldehyde, Alternative oxidase, mitochondrial, ... | | 著者 | Shiba, T, Inaoka, D.K, Takahashi, G, Tsuge, C, Kido, Y, Young, L, Ueda, S, Balogun, E.O, Nara, T, Honma, T, Tanaka, A, Inoue, M, Saimoto, H, Harada, S, Moore, A.L, Kita, K. | | 登録日 | 2018-02-23 | | 公開日 | 2019-02-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Insights into the ubiquinol/dioxygen binding and proton relay pathways of the alternative oxidase.
Biochim Biophys Acta Bioenerg, 1860, 2019
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8P4M
 | | CryoEM structure of a C7-symmetrical GroEL7-GroES7 cage in presence of ADP-BeFx | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chaperonin GroEL, ... | | 著者 | Wagner, J, Beck, F, Bracher, A, Caravajal, A.I, Wan, W, Bohn, S, Koerner, R, Baumeister, W, Fernandez-Busnadiego, R, Hartl, F.U. | | 登録日 | 2023-05-23 | | 公開日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Visualizing chaperonin function in situ by cryo-electron tomography
Nature, 2024
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6RW0
 | | Crystal structure of ANGEL2, a 2',3'-cyclic phosphatase | | 分子名称: | GLYCEROL, MAGNESIUM ION, POTASSIUM ION, ... | | 著者 | Kroupova, A, Jinek, M. | | 登録日 | 2019-06-03 | | 公開日 | 2020-05-20 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | ANGEL2 is a member of the CCR4 family of deadenylases with 2',3'-cyclic phosphatase activity.
Science, 369, 2020
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8OVQ
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8P4R
 | | In situ structure average of GroEL14-GroES14 complexes in Escherichia coli cytosol obtained by cryo electron tomography | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Chaperonin GroEL, Co-chaperonin GroES, ... | | 著者 | Wagner, J, Caravajal, A.I, Beck, F, Bracher, A, Wan, W, Bohn, S, Koerner, R, Baumeister, W, Fernandez-Busnadiego, R, Hartl, F.U. | | 登録日 | 2023-05-23 | | 公開日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (11.9 Å) | | 主引用文献 | Visualizing chaperonin function in situ by cryo-electron tomography
Nature, 2024
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8PAS
 | | Crystal structure of MAP4K1 with a SMOL inhibitor | | 分子名称: | 4-[2,6-bis(fluoranyl)-4-(3-morpholin-4-ylpropylcarbamoylamino)phenoxy]-~{N}-[(4-methyl-1,2,5-oxadiazol-3-yl)methyl]-1~{H}-pyrrolo[2,3-b]pyridine-3-carboxamide, Mitogen-activated protein kinase kinase kinase kinase 1 | | 著者 | Friberg, A. | | 登録日 | 2023-06-08 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Identification and optimization of Azaindole based MAP4K1 Inhibitors and the discovery of BAY-405
To Be Published
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8PAW
 | | Crystal structure of MST1 with a MAP4K1 SMOL inhibitor | | 分子名称: | 1-[3,5-bis(fluoranyl)-4-[[3-(1-propan-2-ylpyrazol-3-yl)-1~{H}-pyrrolo[2,3-b]pyridin-4-yl]oxy]phenyl]-3-(2-methoxyethyl)urea, 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, ASPARTIC ACID, ... | | 著者 | Friberg, A. | | 登録日 | 2023-06-08 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Identification and optimization of Azaindole based MAP4K1 Inhibitors and the discovery of BAY-405
To Be Published
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5ZQ7
 | | SidE-Ubi-NAD | | 分子名称: | ADENOSINE MONOPHOSPHATE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SidE, ... | | 著者 | Wang, Y, Gao, A, Gao, P. | | 登録日 | 2018-04-17 | | 公開日 | 2018-05-23 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.847 Å) | | 主引用文献 | Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE.
Cell, 173, 2018
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8PI8
 | | DNA binding domain of HNF-1A bound to P2-HNF4A promoter DNA | | 分子名称: | Chains: E, Chains: F, GLYCEROL, ... | | 著者 | Kind, L, Myllykoski, M, Raasakka, A, Kursula, P. | | 登録日 | 2023-06-21 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Molecular mechanism of HNF-1A-mediated HNF4A gene regulation and promoter-driven HNF4A-MODY diabetes.
JCI Insight, 9, 2024
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8P4N
 | | CryoEM structure of a GroEL7-GroES7 cage with encapsulated disordered substrate MetK in the presence of ADP-BeFx | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chaperonin GroEL, ... | | 著者 | Wagner, J, Beck, F, Bracher, A, Caravajal, A.I, Wan, W, Bohn, S, Koerner, R, Baumeister, W, Fernandez-Busnadiego, R, Hartl, F.U. | | 登録日 | 2023-05-23 | | 公開日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Visualizing chaperonin function in situ by cryo-electron tomography
Nature, 2024
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8PKB
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8PI7
 | | DNA binding domain of HNF-1A bound to P2-HNF4A promoter DNA variant (P2 -169C>T) | | 分子名称: | CHLORIDE ION, Chains: E, Chains: F, ... | | 著者 | Kind, L, Myllykoski, M, Raasakka, A, Kursula, P. | | 登録日 | 2023-06-21 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Molecular mechanism of HNF-1A-mediated HNF4A gene regulation and promoter-driven HNF4A-MODY diabetes.
JCI Insight, 9, 2024
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6D3V
 | | Chromosomal trehalose-6-phosphate phosphatase from P. aeruginosa | | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, NICKEL (II) ION, ... | | 著者 | Hofmann, A, Cross, M, Park, S.-Y. | | 登録日 | 2018-04-17 | | 公開日 | 2018-05-09 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Trehalose 6-phosphate phosphatases of Pseudomonas aeruginosa.
FASEB J., 32, 2018
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8PI9
 | | DNA binding domain of HNF-1A bound to P2-HNF4A promoter DNA variant (P2 -181G>A) | | 分子名称: | Chains: E, Chains: F, Hepatocyte nuclear factor 1-alpha | | 著者 | Kind, L, Myllykoski, M, Raasakka, A, Kursula, P. | | 登録日 | 2023-06-21 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Molecular mechanism of HNF-1A-mediated HNF4A gene regulation and promoter-driven HNF4A-MODY diabetes.
JCI Insight, 9, 2024
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8P4P
 | | Structure average of GroEL14 complexes found in the cytosol of Escherichia coli overexpressing GroEL obtained by cryo electron tomography | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Chaperonin GroEL, ... | | 著者 | Wagner, J, Caravajal, A.I, Beck, F, Bracher, A, Wan, W, Bohn, S, Koerner, R, Baumeister, W, Fernandez-Busnadiego, R, Hartl, F.U. | | 登録日 | 2023-05-23 | | 公開日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (9.6 Å) | | 主引用文献 | Visualizing chaperonin function in situ by cryo-electron tomography
Nature, 2024
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8P4O
 | | CryoEM structure of a GroEL7-GroES7 cage with encapsulated ordered substrate MetK in the presence of ADP-BeFx | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chaperonin GroEL, ... | | 著者 | Wagner, J, Beck, F, Bracher, A, Caravajal, A.I, Wan, W, Bohn, S, Koerner, R, Baumeister, W, Fernandez-Busnadiego, R, Hartl, F.U. | | 登録日 | 2023-05-23 | | 公開日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | | 主引用文献 | Visualizing chaperonin function in situ by cryo-electron tomography
Nature, 2024
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8OZQ
 | | In situ subtomogram average of Prototype Foamy Virus Env hexamer of trimers | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Calcraft, T, Nans, A, Rosenthal, P.B. | | 登録日 | 2023-05-09 | | 公開日 | 2024-07-10 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (10 Å) | | 主引用文献 | Integrated cryoEM structure of a spumaretrovirus reveals cross-kingdom evolutionary relationships and the molecular basis for assembly and virus entry
Cell(Cambridge,Mass.), 187, 2024
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8OZL
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8P6H
 | | Bovine naive ultralong antibody AbBLV5B8* collected at 100K | | 分子名称: | Antibody BLV5B8* heavy chain, Antibody BLV5B8* light chain | | 著者 | Clarke, J.D, Douangamath, A, Mikolajek, H, Stuart, D.I, Owens, R.J. | | 登録日 | 2023-05-26 | | 公開日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | The impact of chain-exchange on bovine ultralong immunoglobulins.
Acta Crystallographica Section F, 2023
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8OZJ
 | | In situ cryoEM structure of Prototype Foamy Virus Env dimer of trimers | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Calcraft, T, Nans, A, Rosenthal, P.B. | | 登録日 | 2023-05-09 | | 公開日 | 2024-07-10 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Integrated cryoEM structure of a spumaretrovirus reveals cross-kingdom evolutionary relationships and the molecular basis for assembly and virus entry
Cell(Cambridge,Mass.), 187, 2024
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5ZRG
 | | M. smegmatis antimutator protein MutT2 in complex with dCMP | | 分子名称: | 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, Putative mutator protein MutT2/NUDIX hydrolase | | 著者 | Singh, A, Arif, S.M, Sang, P.B, Varshney, U, Vijayan, M. | | 登録日 | 2018-04-24 | | 公開日 | 2019-04-24 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structural insights into the specificity and catalytic mechanism of mycobacterial nucleotide pool sanitizing enzyme MutT2.
J.Struct.Biol., 204, 2018
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8OZN
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8PIP
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