Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
6D8R
DownloadVisualize
BU of 6d8r by Molmil
NMR solution structure of tamapin, mutant E25K
分子名称: Potassium channel toxin alpha-KTx 5.4
著者del Rio Portilla, F, Melchor Meneses, C.M, Titaux Delgado, G.A, Mayorga Flores, M.
登録日2018-04-26
公開日2019-05-01
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells
Acs Med.Chem.Lett., 2020
6D8U
DownloadVisualize
BU of 6d8u by Molmil
NMR solution structure of tamapin, mutant K20E
分子名称: Potassium channel toxin alpha-KTx 5.4
著者del Rio Portilla, F, Melchor Meneses, C.M, Titaux Delgado, G.A, Mayorga Flores, M.
登録日2018-04-26
公開日2019-05-01
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells
Acs Med.Chem.Lett., 2020
6D9P
DownloadVisualize
BU of 6d9p by Molmil
NMR solution structure of tamapin, mutant K27A
分子名称: Potassium channel toxin alpha-KTx 5.4
著者del Rio Portilla, F, Melchor Meneses, C.M, Titaux Delgado, G.A, Mayorga Flores, M.
登録日2018-04-30
公開日2019-05-08
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells
Acs Med.Chem.Lett., 2020
6D8Y
DownloadVisualize
BU of 6d8y by Molmil
NMR solution structure of tamapin, mutant Y31H
分子名称: Potassium channel toxin alpha-KTx 5.4
著者del Rio Portilla, F, Melchor Meneses, C.M, Titaux Delgado, G.A, Mayorga Flores, M.
登録日2018-04-27
公開日2019-05-01
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells
Acs Med.Chem.Lett., 2020
6D93
DownloadVisualize
BU of 6d93 by Molmil
NMR solution structure of tamapin, mutant Y31A
分子名称: Potassium channel toxin alpha-KTx 5.4
著者del Rio Portilla, F, Melchor Meneses, C.M, Titaux Delgado, G.A, Mayorga Flores, M.
登録日2018-04-27
公開日2019-05-01
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells
Acs Med.Chem.Lett., 2020
6D3T
DownloadVisualize
BU of 6d3t by Molmil
NMR solution structure of tamapin, mutant DP30
分子名称: Potassium channel toxin alpha-KTx 5.4
著者del Rio Portilla, F, Melchor Meneses, C.M, Titaux Delgado, G, Mayorga Flores, M.
登録日2018-04-16
公開日2019-07-17
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells
Acs Med.Chem.Lett., 2020
6D8S
DownloadVisualize
BU of 6d8s by Molmil
NMR solution structure of tamapin, mutant K27E
分子名称: Potassium channel toxin alpha-KTx 5.4
著者del Rio Portilla, F, Melchor Meneses, C.M, Titaux Delgado, G.A, Mayorga Flores, M.
登録日2018-04-26
公開日2019-05-01
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells
Acs Med.Chem.Lett., 2020
1QYG
DownloadVisualize
BU of 1qyg by Molmil
ANTI-COCAINE ANTIBODY M82G2 COMPLEXED WITH BENZOYLECGONINE
分子名称: 3-(BENZOYLOXY)-8-METHYL-8-AZABICYCLO[3.2.1]OCTANE-2-CARBOXYLIC ACID, FAB M82G2, HEAVY CHAIN, ...
著者Pozharski, E, Hewagama, A, Shanafelt, A, Petsko, G, Ringe, D.
登録日2003-09-10
公開日2003-09-23
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Diversity in hapten recognition: structural study of an anti-cocaine antibody M82G2.
J.Mol.Biol., 349, 2005
5XHI
DownloadVisualize
BU of 5xhi by Molmil
Crystal structure of Frog M-ferritin D38A mutant
分子名称: CHLORIDE ION, Ferritin, middle subunit, ...
著者Jagdev, M.K, Vasudevan, D.
登録日2017-04-21
公開日2017-08-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Surface charge dependent separation of modified and hybrid ferritin in native PAGE: Impact of lysine 104
Biochim. Biophys. Acta, 1865, 2017
5XHO
DownloadVisualize
BU of 5xho by Molmil
Crystal structure of Frog M-ferritin E135K mutant
分子名称: CHLORIDE ION, Ferritin, middle subunit, ...
著者Jagdev, M.K, Vasudevan, D.
登録日2017-04-21
公開日2017-08-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Surface charge dependent separation of modified and hybrid ferritin in native PAGE: Impact of lysine 104
Biochim. Biophys. Acta, 1865, 2017
6EIA
DownloadVisualize
BU of 6eia by Molmil
PepTSt in complex with HEPES (100 mM)
分子名称: (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Martinez Molledo, M, Quistgaard, E.M, Loew, C.
登録日2017-09-18
公開日2018-02-21
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Multispecific Substrate Recognition in a Proton-Dependent Oligopeptide Transporter.
Structure, 26, 2018
5AIU
DownloadVisualize
BU of 5aiu by Molmil
A complex of RNF4-RING domain, Ubc13-Ub (isopeptide crosslink)
分子名称: 1,2-ETHANEDIOL, E3 UBIQUITIN-PROTEIN LIGASE RNF4, POLYUBIQUITIN-C, ...
著者Branigan, E, Naismith, J.H.
登録日2015-02-17
公開日2015-07-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Structural Basis for the Ring Catalyzed Synthesis of K63 Linked Ubiquitin Chains
Nat.Struct.Mol.Biol., 22, 2015
1C2X
DownloadVisualize
BU of 1c2x by Molmil
5S RRNA STRUCTURE FITTED TO A CRYO-ELECTRON MICROSCOPIC MAP AT 7.5 ANGSTROMS RESOLUTION
分子名称: 5S RIBOSOMAL RNA
著者Brimacombe, R, Mueller, F.
登録日1999-07-28
公開日2000-04-10
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (7.5 Å)
主引用文献The 3D arrangement of the 23 S and 5 S rRNA in the Escherichia coli 50 S ribosomal subunit based on a cryo-electron microscopic reconstruction at 7.5 A resolution.
J.Mol.Biol., 298, 2000
4HVI
DownloadVisualize
BU of 4hvi by Molmil
JAK3 kinase domain in complex with 2-Cyclopropyl-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid ((R)-1-methyl-2-oxo-2-piperidin-1-yl-ethyl)-amide
分子名称: 2-cyclopropyl-N-[(2R)-1-oxo-1-(piperidin-1-yl)propan-2-yl]-5H-pyrrolo[2,3-b]pyrazine-7-carboxamide, Tyrosine-protein kinase JAK3
著者Kuglstatter, A, Shao, A.
登録日2012-11-06
公開日2013-01-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献3-Amido Pyrrolopyrazine JAK Kinase Inhibitors: Development of a JAK3 vs JAK1 Selective Inhibitor and Evaluation in Cellular and in Vivo Models.
J.Med.Chem., 56, 2013
5AIT
DownloadVisualize
BU of 5ait by Molmil
A complex of of RNF4-RING domain, UbeV2, Ubc13-Ub (isopeptide crosslink)
分子名称: E3 UBIQUITIN-PROTEIN LIGASE RNF4, POLYUBIQUITIN-C, UBIQUITIN-CONJUGATING ENZYME E2 N, ...
著者Branigan, E, Naismith, J.H.
登録日2015-02-17
公開日2015-07-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural Basis for the Ring Catalyzed Synthesis of K63 Linked Ubiquitin Chains
Nat.Struct.Mol.Biol., 22, 2015
4HVG
DownloadVisualize
BU of 4hvg by Molmil
JAK3 kinase domain in complex with 2-Cyclopropyl-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid ((S)-2-hydroxy-1,2-dimethyl-propyl)-amide
分子名称: 2-cyclopropyl-N-[(2S)-3-hydroxy-3-methylbutan-2-yl]-5H-pyrrolo[2,3-b]pyrazine-7-carboxamide, Tyrosine-protein kinase JAK3
著者Kuglstatter, A, Shao, A.
登録日2012-11-06
公開日2013-01-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献3-Amido Pyrrolopyrazine JAK Kinase Inhibitors: Development of a JAK3 vs JAK1 Selective Inhibitor and Evaluation in Cellular and in Vivo Models.
J.Med.Chem., 56, 2013
5LQS
DownloadVisualize
BU of 5lqs by Molmil
Structure of quinolinate synthase Y21F mutant in complex with substrate-derived quinolinate
分子名称: CHLORIDE ION, IRON/SULFUR CLUSTER, QUINOLINIC ACID, ...
著者Volbeda, A, Fontecilla-Camps, J.C.
登録日2016-08-17
公開日2016-08-31
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structures of Quinolinate Synthase in Complex with a Substrate Analogue, the Condensation Intermediate, and Substrate-Derived Product.
J.Am.Chem.Soc., 138, 2016
4HVH
DownloadVisualize
BU of 4hvh by Molmil
JAK3 kinase domain in complex with 2-Cyclopropyl-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid ((R)-2-hydroxy-1,2-dimethyl-propyl
分子名称: 2-cyclopropyl-N-[(2R)-3-hydroxy-3-methylbutan-2-yl]-5H-pyrrolo[2,3-b]pyrazine-7-carboxamide, Tyrosine-protein kinase JAK3
著者Kuglstatter, A, Shao, A.
登録日2012-11-06
公開日2013-01-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献3-Amido Pyrrolopyrazine JAK Kinase Inhibitors: Development of a JAK3 vs JAK1 Selective Inhibitor and Evaluation in Cellular and in Vivo Models.
J.Med.Chem., 56, 2013
7U0P
DownloadVisualize
BU of 7u0p by Molmil
SARS-Cov2 S protein structure in complex with neutralizing monoclonal antibody 002-S21F2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Patel, A, Ortlund, E.
登録日2022-02-18
公開日2022-08-10
最終更新日2023-02-22
実験手法ELECTRON MICROSCOPY (3.76 Å)
主引用文献Structural insights for neutralization of Omicron variants BA.1, BA.2, BA.4, and BA.5 by a broadly neutralizing SARS-CoV-2 antibody.
Sci Adv, 8, 2022
4HVD
DownloadVisualize
BU of 4hvd by Molmil
JAK3 kinase domain in complex with 2-Cyclopropyl-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid ((S)-1,2,2-trimethyl-propyl)-amide
分子名称: 1-phenylurea, 2-cyclopropyl-N-[(2S)-3,3-dimethylbutan-2-yl]-5H-pyrrolo[2,3-b]pyrazine-7-carboxamide, Tyrosine-protein kinase JAK3
著者Kuglstatter, A, Shao, A.
登録日2012-11-06
公開日2013-01-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献3-Amido Pyrrolopyrazine JAK Kinase Inhibitors: Development of a JAK3 vs JAK1 Selective Inhibitor and Evaluation in Cellular and in Vivo Models.
J.Med.Chem., 56, 2013
7UPL
DownloadVisualize
BU of 7upl by Molmil
SARS-Cov2 Omicron varient S protein structure in complex with neutralizing monoclonal antibody 002-S21F2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Patel, A, Ortlund, E.
登録日2022-04-15
公開日2022-08-10
最終更新日2023-02-22
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural insights for neutralization of Omicron variants BA.1, BA.2, BA.4, and BA.5 by a broadly neutralizing SARS-CoV-2 antibody.
Sci Adv, 8, 2022
7UOW
DownloadVisualize
BU of 7uow by Molmil
SARS-Cov2 S protein structure in complex with neutralizing monoclonal antibody 034_32
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Monoclonal antibody 034_32 heavy chain, ...
著者Patel, A, Ortlund, E.
登録日2022-04-14
公開日2023-04-19
最終更新日2023-09-13
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response.
Structure, 31, 2023
8W00
DownloadVisualize
BU of 8w00 by Molmil
Q108K:K40L:T51V:T53S:Y19W:R58W:L117E mutant of hCRBPII bound to synthetic fluorophore TD-1V
分子名称: (2E)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}but-2-enal, ACETATE ION, Retinol-binding protein 2
著者Nossoni, Z, Bingham, C.R, Geiger, J.H.
登録日2024-02-13
公開日2024-04-03
実験手法X-RAY DIFFRACTION (1.23 Å)
主引用文献Regulation of Emission via a Protein-Bound Fluorophore
To Be Published
8VZX
DownloadVisualize
BU of 8vzx by Molmil
Q108K:K40L:T53A:R58F mutant of hCRBPII bound to synthetic fluorophore TD-1V
分子名称: (2E)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}but-2-enal, ACETATE ION, Retinol-binding protein 2
著者Nossoni, Z, Bingham, C.R, Geiger, J.H.
登録日2024-02-13
公開日2024-04-03
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Regulation of Emission via a Protein-Bound Fluorophore
To Be Published
8PKE
DownloadVisualize
BU of 8pke by Molmil
ATTRV20I amyloid fibril from hereditary ATTR amloidosis
分子名称: Transthyretin
著者Steinebrei, M, Schmidt, M, Faendrich, M.
登録日2023-06-26
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (3.39 Å)
主引用文献Common transthyretin-derived amyloid fibril structures in patients with hereditary ATTR amyloidosis.
Nat Commun, 14, 2023

222415

件を2024-07-10に公開中

PDB statisticsPDBj update infoContact PDBjnumon