1LTQ
| CRYSTAL STRUCTURE OF T4 POLYNUCLEOTIDE KINASE | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DIMETHYL SULFOXIDE, POLYNUCLEOTIDE KINASE | 著者 | Galburt, E.A, Pelletier, J, Wilson, G, Stoddard, B.L. | 登録日 | 2002-05-20 | 公開日 | 2002-10-09 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Structure of a tRNA repair enzyme and molecular biology workhorse: T4 polynucleotide kinase. Structure, 10, 2002
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1IDD
| ISOCITRATE DEHYDROGENASE Y160F MUTANT APO ENZYME | 分子名称: | ISOCITRATE DEHYDROGENASE | 著者 | Lee, M.E, Dyer, D.H, Klein, O.D, Bolduc, J.M, Stoddard, B.L, Koshland Junior, D.E. | 登録日 | 1995-01-18 | 公開日 | 1996-03-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Mutagenesis and Laue structures of enzyme intermediates: isocitrate dehydrogenase. Science, 268, 1995
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1M5X
| Crystal structure of the homing endonuclease I-MsoI bound to its DNA substrate | 分子名称: | 5'-D(*CP*GP*GP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*TP*TP*CP*TP*GP*C)-3', 5'-D(*GP*CP*AP*GP*AP*AP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*CP*CP*G)-3', CALCIUM ION, ... | 著者 | Chevalier, B, Turmel, M, Lemieux, C, Monnat, R.J, Stoddard, B.L. | 登録日 | 2002-07-10 | 公開日 | 2003-06-03 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Flexible DNA Target Site Recognition by Divergent Homing Endonuclease Isoschizomers I-CreI and I-MsoI J.Mol.Biol., 329, 2003
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1A73
| INTRON-ENCODED ENDONUCLEASE I-PPOI COMPLEXED WITH DNA | 分子名称: | DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*A)-3'), DNA (5'-D(P*GP*AP*GP*AP*GP*TP*CP*A)-3'), INTRON 3 (I-PPO) ENCODED ENDONUCLEASE, ... | 著者 | Flick, K.E, Monnat Junior, R.J, Stoddard, B.L. | 登録日 | 1998-03-19 | 公開日 | 1998-10-14 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | DNA binding and cleavage by the nuclear intron-encoded homing endonuclease I-PpoI. Nature, 394, 1998
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4OUD
| Engineered tyrosyl-tRNA synthetase with the nonstandard amino acid L-4,4-biphenylalanine | 分子名称: | TYROSINE, Tyrosyl-tRNA synthetase | 著者 | Takeuchi, R, Mandell, D.J, Lajoie, M.J, Church, G.M, Stoddard, B.L. | 登録日 | 2014-02-16 | 公開日 | 2015-01-28 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Biocontainment of genetically modified organisms by synthetic protein design. Nature, 518, 2015
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4R6J
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4R6G
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4R5D
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4R58
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4R5C
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4QQ8
| Crystal structure of the formolase FLS in space group P 43 21 2 | 分子名称: | 1,2-ETHANEDIOL, Formolase, MAGNESIUM ION, ... | 著者 | Shen, B.W, Siegel, J.B, Stoddard, B.L. | 登録日 | 2014-06-26 | 公開日 | 2015-03-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | 主引用文献 | Computational protein design enables a novel one-carbon assimilation pathway. Proc.Natl.Acad.Sci.USA, 112, 2015
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4QPZ
| Crystal structure of the formolase FLS_v2 in space group P 21 | 分子名称: | Formolase, MAGNESIUM ION, THIAMINE DIPHOSPHATE | 著者 | Shen, B.W, Siegel, J.B, Stoddard, B.L, Baker, D. | 登録日 | 2014-06-25 | 公開日 | 2015-03-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Computational protein design enables a novel one-carbon assimilation pathway. Proc.Natl.Acad.Sci.USA, 112, 2015
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4R6F
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3MIP
| I-MsoI re-designed for altered DNA cleavage specificity (-8GCG) | 分子名称: | CALCIUM ION, DNA (5'-D(*CP*GP*GP*AP*GP*CP*GP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*CP*GP*CP*CP*TP*GP*C)-3'), DNA (5'-D(*GP*CP*AP*GP*GP*CP*GP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*CP*GP*CP*TP*CP*CP*G)-3'), ... | 著者 | Taylor, G.K, Stoddard, B.L. | 登録日 | 2010-04-11 | 公開日 | 2010-05-19 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Computational reprogramming of homing endonuclease specificity at multiple adjacent base pairs. Nucleic Acids Res., 38, 2010
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3M7K
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3MIS
| I-MsoI re-designed for altered DNA cleavage specificity (-8G) | 分子名称: | CALCIUM ION, DNA (5'-D(*CP*GP*GP*AP*GP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*TP*CP*CP*TP*GP*C)-3'), DNA (5'-D(*GP*CP*AP*GP*GP*AP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*CP*TP*CP*CP*G)-3'), ... | 著者 | Taylor, G.K, Stoddard, B.L. | 登録日 | 2010-04-12 | 公開日 | 2010-05-19 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Computational reprogramming of homing endonuclease specificity at multiple adjacent base pairs. Nucleic Acids Res., 38, 2010
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3NIC
| DNA binding and cleavage by the GIY-YIG endonuclease R.Eco29kI inactive variant Y49F | 分子名称: | DNA (5'-D(P*CP*GP*GP*GP*AP*GP*GP*CP*CP*CP*GP*CP*GP*GP*GP*CP*CP*GP*CP*CP*GP*C)-3'), DNA (5'-D(P*GP*CP*GP*GP*CP*GP*GP*CP*CP*CP*GP*CP*GP*GP*GP*CP*CP*TP*CP*CP*CP*G)-3'), Eco29kIR, ... | 著者 | Mak, A.N.S, Lambert, A.R, Stoddard, B.L. | 登録日 | 2010-06-15 | 公開日 | 2010-09-08 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Folding, DNA Recognition, and Function of GIY-YIG Endonucleases: Crystal Structures of R.Eco29kI. Structure, 18, 2010
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3MX1
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3MX4
| DNA binding and cleavage by the GIY-YIG endonuclease R.Eco29KI inactive variant E142Q | 分子名称: | DNA (5'-D(P*CP*GP*GP*GP*AP*GP*GP*CP*CP*CP*GP*CP*GP*GP*GP*CP*CP*GP*CP*CP*GP*C)-3'), DNA (5'-D(P*GP*CP*GP*GP*CP*GP*GP*CP*CP*CP*GP*CP*GP*GP*GP*CP*CP*TP*CP*CP*CP*G)-3'), Eco29kIR | 著者 | Mak, A.N.S, Lambert, A.R, Stoddard, B.L. | 登録日 | 2010-05-06 | 公開日 | 2010-09-08 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Folding, DNA Recognition, and Function of GIY-YIG Endonucleases: Crystal Structures of R.Eco29kI. Structure, 18, 2010
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1U0D
| Y33H Mutant of Homing endonuclease I-CreI | 分子名称: | 5'-D(*CP*GP*GP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*TP*TP*TP*CP*GP*C)-3', 5'-D(*GP*CP*GP*AP*AP*AP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*CP*CP*G)-3', DNA endonuclease I-CreI | 著者 | Sussman, D, Chadsey, M, Fauce, S, Engel, A, Bruett, A, Monnat, R, Stoddard, B.L, Seligman, L.M. | 登録日 | 2004-07-13 | 公開日 | 2004-11-02 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Isolation and characterization of new homing endonuclease specificities at individual target site positions. J.Mol.Biol., 342, 2004
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1U3E
| DNA binding and cleavage by the HNH homing endonuclease I-HmuI | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 36-MER, ... | 著者 | Shen, B.W, Landthaler, M, Shub, D.A, Stoddard, B.L. | 登録日 | 2004-07-21 | 公開日 | 2004-08-31 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | 主引用文献 | DNA Binding and Cleavage by the HNH Homing Endonuclease I-HmuI. J.Mol.Biol., 342, 2004
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1R9X
| Bacterial cytosine deaminase D314G mutant. | 分子名称: | Cytosine deaminase, FE (III) ION, GLYCEROL, ... | 著者 | Mahan, S.D, Ireton, G.C, Stoddard, B.L, Black, M.E. | 登録日 | 2003-10-31 | 公開日 | 2004-10-05 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Random mutagenesis and selection of Escherichia coli cytosine deaminase for cancer gene therapy. Protein Eng.Des.Sel., 17, 2004
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3I1C
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1RC8
| T4 Polynucleotide Kinase bound to 5'-GTCAC-3' ssDNA | 分子名称: | 5'-D(*GP*TP*CP*AP*C)-3', ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... | 著者 | Eastberg, J.H, Pelletier, J, Stoddard, B.L. | 登録日 | 2003-11-03 | 公開日 | 2004-02-17 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Recognition of DNA substrates by T4 bacteriophage polynucleotide kinase. Nucleic Acids Res., 32, 2004
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1RA0
| Bacterial cytosine deaminase D314G mutant bound to 5-fluoro-4-(S)-hydroxy-3,4-dihydropyrimidine. | 分子名称: | (4S)-5-FLUORO-4-HYDROXY-3,4-DIHYDROPYRIMIDIN-2(1H)-ONE, Cytosine deaminase, FE (III) ION | 著者 | Mahan, S.D, Ireton, G.C, Stoddard, B.L, Black, M.E. | 登録日 | 2003-10-31 | 公開日 | 2004-10-05 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | 主引用文献 | Random mutagenesis and selection of Escherichia coli cytosine deaminase for cancer gene therapy. Protein Eng.Des.Sel., 17, 2004
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